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SEPTA to Restore Train Service to Claymont & Wilmington Starting May 10

Please be advised that SEPTA Train Service to Claymont and Wilmington will resume daily service effective Sunday, May 10

For more information and schedule details, please visit www.septa.org. 

 

Thanks for riding!




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Governor Carney and Five Governors Announce Multi-State Council to Get People Back to Work and Restore the Economy

Council Will Include One Health Expert, One Economic Development Expert and Respective Chiefs of Staff from Each State Council Will Develop a Fully Integrated Regional Framework to Gradually Lift the States’ Stay at Home Orders While Minimizing the Risk of Increased Spread of the Virus New Effort Builds on the States’ ongoing Regional Approach to […]




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Jammu and Kashmir: SMS restored, broadband internet back in govt hospitals

SHORT messaging services (SMS) on mobile phones will be restored in Jammu and Kashmir Tuesday midnight, the 150th day since the government suspended it in the erstwhile state.




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UAE airlines say years needed to restore demand

Top executives of Emirates and Etihad, two of the Middle East's biggest airlines, have said passenger demand may not return to pre-coronavirus crisis levels until 2023.




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How do we use the concept of Save and Restore during real developing(debugging)???/

Hi All,

I'm trying to understand checkpoint concept. When I found save and restart concept in cdnshelp, There is just describing about "$save" and "xrun -r "~~~".

and I found also the below link about save restart and it saves your time.

But I can't find any benefits from my experiment from save&restart article( I fully agree..the article)

Ok, So I'v got some experiment  Here.

1. I declared $save and got the below result as I expected within the simple UVM code.

In UVM code...

$display("TEST1");
$display("TEST2");
$save("SAVE_TEST");
$display("TEST3");
$display("TEST4");

And I restart at "SAVE_TEST" point by xrun -r "SAVE_TEST", I've got the below log

xcelium> run
TEST3
TEST4

Ok, It's Good what I expected.(The concept of Save and Restore is simple: instead of re-initializing your simulation every time you want to run a test, only initialize it once. Then you can save the simulation as a “snapshot” and re-run it from that point to avoid hours of initialization times. It used to be inconvenient. I agree..)

2. But The Problem is that I can't restart with modified code. Let's see the below example.

I just modified TEST5 instead of "TEST3"

$display("TEST1");
$display("TEST2");
$save("SAVE_TEST");
$display("TEST5"); //$display("TEST3");
$display("TEST4");

and I rerun with xrun -r "SAVE_TEST", then I've got the same log

xcelium> run
TEST3
TEST4

There is no "TEST5". Actually I expected "TEST5" in the log.From here We know $save can't support partially modified code after $save. 

Actually, through this, we can approach to our goal about saving developing time. 

So I want to know Is there any possible way that instead of re-initializing our simulation every time we want to run a test, only initialize it once and keep developing(debugging) our code ?

If we do, Could you let me know the simple example?




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Regarding Save/Restore Settings for Transient Simulation

Hello,

I am running a transient simulation on my circuit and usually my simulation time took me more than a day (The circuit is quite big). I am usually saving specific nodes to decrease the simulation time. My problem is, since it usually took me one day to finish I need to save my trans simulation just in case something bad happens. I am aware that the transient simulation have the options for save/restore. But, when I tried to use it I have some problem. Whenever I restore the save file, it starts where it ends before (expected function) but my data is incomplete. It doesn't save the previous data. Its kind of my data is incomplete. What I did is set the saveperiod and savefile. I hope someone can help me. Thank you!


Regards,

Kiel




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Verisign Will Waive Wholesale Restore Fee to Help Registrants Keep Their Domain Names During COVID-19 Crisis

Last week, we announced a number of actions we are taking to support our people and community during the global COVID-19 crisis. Today, we’re pleased to provide more detail about one of those actions, which, with the help of registrars, will make it easier for domain name registrants worldwide to keep their domain names in […]

The post Verisign Will Waive Wholesale Restore Fee to Help Registrants Keep Their Domain Names During COVID-19 Crisis appeared first on Verisign Blog.





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Back in Touch: Technology Restores Hand Sensitivity to Young Quadraplegic

Title: Back in Touch: Technology Restores Hand Sensitivity to Young Quadraplegic
Category: Health News
Created: 4/23/2020 12:00:00 AM
Last Editorial Review: 4/24/2020 12:00:00 AM




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NO-Releasing Nanoparticles Ameliorate Detrusor Overactivity in Transgenic Sickle Cell Mice via Restored NO/ROCK Signaling [Cellular and Molecular]

Sickle cell disease (SCD) is associated with overactive bladder (OAB). Detrusor overactivity, a component of OAB, is present in an SCD mouse, but the molecular mechanisms for this condition are not well-defined. We hypothesize that nitric oxide (NO)/ ras homolog gene family (Rho) A/Rho-associated kinase (ROCK) dysregulation is a mechanism for detrusor overactivity and that NO-releasing nanoparticles (NO-nps), a novel NO delivery system, may serve to treat this condition. Male adult SCD transgenic, combined endothelial NO synthases (eNOSs) and neuronal NOS (nNOS) gene-deficient (dNOS–/–), and wild-type (WT) mice were used. Empty nanoparticle or NO-np was injected into the bladder, followed by cystometric studies. The expression levels of phosphorylated eNOS (Ser-1177), protein kinase B (Akt) (Ser-473), nNOS (Ser-1412), and myosin phosphatase target subunit 1 (MYPT1) (Thr-696) were assessed in the bladder. SCD and dNOS–/– mice had a greater (P < 0.05) number of voiding and nonvoiding contractions compared with WT mice, and they were normalized by NO-np treatment. eNOS (Ser-1177) and AKT (Ser-473) phosphorylation were decreased (P < 0.05) in the bladder of SCD compared with WT mice and reversed by NO-np. Phosphorylated MYPT1, a marker of the RhoA/ROCK pathway, was increased (P < 0.05) in the bladder of SCD mice compared with WT and reversed by NO-np. nNOS phosphorylation on positive (Ser-1412) regulatory site was decreased (P < 0.05) in the bladder of SCD mice compared with WT and was not affected by NO-np. NO-nps did not affect any of the measured parameters in WT mice. In conclusion, dysregulation of NO and RhoA/ROCK pathways is associated with detrusor overactivity in SCD mice; NO-np reverses these molecular derangements in the bladder and decreases detrusor overactivity.

SIGNIFICANCE STATEMENT

Voiding abnormalities commonly affect patients with sickle cell disease (SCD) but are problematic to treat. Clarification of the science for this condition in an animal model of SCD may lead to improved interventions for it. Our findings suggest that novel topical delivery of a vasorelaxant agent nitric oxide into the bladder of these mice corrects overactive bladder by improving deranged bladder physiology regulatory signaling.




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Comparison of Treatment Outcomes between Analysis Populations in the RESTORE-IMI 1 Phase 3 Trial of Imipenem-Cilastatin-Relebactam versus Colistin plus Imipenem-Cilastatin in Patients with Imipenem-Nonsusceptible Bacterial Infections [Clinical Therapeutic

The RESTORE-IMI 1 phase 3 trial demonstrated the efficacy and safety of imipenem-cilastatin (IMI) combined with relebactam (REL) for treating imipenem-nonsusceptible infections. The objective of this analysis was to compare the outcomes among patients meeting eligibility requirements based on central laboratory susceptibility versus local laboratory susceptibility. Patients with serious infections caused by imipenem-nonsusceptible, colistin-susceptible, and imipenem-REL-susceptible pathogens were randomized 2:1 to IMI-REL plus placebo or colistin plus IMI for 5 to 21 days. The primary endpoint was a favorable overall response. Key endpoints included the clinical response and all-cause mortality. We compared outcomes between the primary microbiological modified intent-to-treat (mMITT) population, where eligibility was based on central laboratory susceptibility testing, and the supplemental mMITT (SmMITT) population, where eligibility was based on local, site-level testing. The SmMITT (n = 41) and MITT (n = 31) populations had similar baseline characteristics, including sex, age, illness severity, and renal function. In both analysis populations, favorable overall response rates in the IMI-REL treatment group were >70%. Favorable clinical response rates at day 28 were 71.4% for IMI-REL and 40.0% for colistin plus IMI in the mMITT population, whereas they were 75.0% for IMI-REL and 53.8% for colistin plus IMI in the SmMITT population. Day 28 all-cause mortality rates were 9.5% for IMI-REL and 30.0% for colistin plus IMI in the mMITT population, whereas they were 10.7% for IMI-REL and 23.1% for colistin plus IMI in the SmMITT population. The outcomes in the SmMITT population were generally consistent with those in the mMITT population, suggesting that outcomes may be applicable to the real-world use of IMI-REL for treating infections caused by imipenem-nonsusceptible Gram-negative pathogens. (This study has been registered at ClinicalTrials.gov under identifier NCT02452047.)




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Some NHS services paused due to coronavirus to be restored as number of Covid-19 patients in hospital falls

NHS services including cancer care and mental health support which were paused due to the coronavirus outbreak will be restored from Tuesday, Matt Hancock has announced.




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Sydney news: Evacuations after factory fire near Alexandria, bus services restored for Hills district

MORNING BRIEFING: More than 90 fire fighters work to stop a factory blaze from spreading in Sydney's inner city, while 700 weekly buses are being added to the Hills District.




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Stalwarts help restore Dragons' pride

St George Illawarra coach Paul McGregor has turned to two of the Dragons' fiercest competitors to help restore pride and passion to the club.




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Boeing to Restore Significant Habitat in Washington State Waterway to Resolve Natural Resource Damage Liability

The Boeing Company has agreed to undertake two significant habitat restoration projects in Washington state to resolve its liability for natural resource damages caused by hazardous substances released from Boeing facilities along the Duwamish Waterway.



  • OPA Press Releases

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Triad Mining Agrees to Resolve Clean Water Act Violations and Restore Affected Waterways in Indiana

Triad Mining Inc., the owner and operator of 31 surface mines in Appalachia and Indiana, has agreed to pay a penalty and to restore affected waterways for failing to obtain the required Clean Water Act (CWA) permit for stream impacts caused by its surface mining operation in Indiana.



  • OPA Press Releases

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Trans Energy Inc. to Restore Streams and Wetland Damaged by Natural Gas Extraction Activities in West Virginia

The Department of Justice, the U.S. Environmental Protection Agency (EPA) and the West Virginia Department of Environmental Protection (WVDEP) today announced a settlement with Trans Energy Inc., requiring the oil and gas company to restore portions of streams and wetlands at 15 sites in West Virginia that were polluted by the company’s unauthorized discharge of dredge or fill material. Trans Energy will pay a penalty of $3 million to be divided equally between the federal government and the WVDEP. The Clean Water Act requires a company to obtain a permit from EPA and the U.S. Army Corps of Engineers prior to discharging dredge or fill material into wetlands, rivers, streams and other waters of the United States.



  • OPA Press Releases

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Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide




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Is deterrence restored with Iran?

Just after the United States killed Iranian military leader Qassem Soleimani, Secretary of State Mike Pompeo justified the attack by claiming: “The entire strategy has been one of deterrence.” Indeed, history may judge the killing based on whether it provokes a spiral that leads to more Iranian and U.S. attacks or helps convince Iran to…

       




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How to restore U.S.-Japan relations on Okinawa


The U.S.-Japan alliance continues to struggle with the issue of reducing and relocating the U.S. Marine Corps presence on Okinawa.  In a new op-ed in the Wall Street Journal, Mike Mochizuki (of The George Washington University) and I—recognizing the potential seriousness of this problem for the alliance, as well as the fact that the current plan to reduce and/or relocate has been straitjacketed by Japanese and Okinawan politics—propose a more significant set of changes. Our proposal would scale back the peacetime presence of the Marines on Okinawa even further than now planned, but it would preserve or even improve U.S. military responsiveness throughout the Western Pacific region in times of crisis or conflict.

     
 
 




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Biggest Bucky Fuller Fly Eye Dome being restored and moved to France

Robert Rubin saves " the last, monumental prototype that Bucky was working on when he died".




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Scientists call for more trees, fewer cows, to restore climate

First we have to declare 'peak livestock', then eat less beef and more beans.




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Scott's 103 year old prefab cabin in Antarctica is lovingly restored

After ten years of work, the Antarctic Heritage Trust has done an amazing job of restoring and preserving.




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100-1000 And Restore Coastal Alabama Partnership's Inaugural Massive Oyster Reef Restoration

Last weekend, January 22nd - 23rd , over 500 volunteers from Alabama and across the country came together in Mobile Bay to lay the beginnings of oyster reefs. The volunteers strapped on boots




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Eero Saarinen's TWA terminal is restored, repurposed and reborn as the TWA Hotel

Did we say we hate concrete? Just the new stuff. This kind of concrete should be buffed, polished and treasured.




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Restored church building has a growing congregation – of bees

ZGF builds interesting hives on the roof of a fascinating building.




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Elections derail display of restored tram coach

A missing platform stands between Mumbaikars and the restored tram the Brihanmumbai Municipal Corporation (BMC) had promised to set up for display at Bhatia Baug, by the first week of April. While the tram coach is nearly ready, the tender for construction of the platform, which will serve as its base, didn't receive an adequate response, and a second tender cannot be floated until after the Lok Sabha elections in the city.

The BMC floated a tender last month to appoint a contractor who will construct a 3 feet tall platform. The tram, as well as part of tracks, will be installed on top of it. The overall of cost of restoration of the tram and construction of the platform is estimated to be R28 lakh. "We received a response from a single bidder so we have to float another tender. However, since the model code of conduct is in place, we will have to wait for the elections to get over," said Kiran Dighavkar, assistant municipal commissioner of A ward. He added that they will float the tender next week and it will remain open for a period of eight days.

Also read: Elections 2019: 422 polling stations in Mumbai declared 'critical'

Based on the plan, the BMC is considering letting people enter the tram under certain conditions. Before the final setup, however, the BMC will need the approval of the heritage committee. Unlike most projects that are approved based on documents, for this project, the committee members will have to inspect the tram. On April 24, A ward officials wrote to the heritage committee asking them to inspect the tram and give their approval for the project. Dighavkar added that the tram will be brought to a godown in Cuffe Parade from Rabale sometime this week.

Over the past couple of months, the tram was restored in a workshop in Rabale using the parts of another tram that was functional in Kolkata between 1874 and 1907. Once the tram has been assembled at Bhatia Baug, the BMC is planning to set up lighting in the area to attract visitors. Civic officials are also planning to install LED screens inside the tram which will display information about the history of trams in Mumbai from the horse drawn ones till the electrical ones which were taken off the road around 50 years ago.

Also read: Elections 2019: Netas appeal to citizens to vote

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates





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New Study Helps Restore Hormonal Balance Disrupted in Metabolic Diseases

The molecular mechanisms that trigger metabolic imbalance between the two distinct but linked processes have been discovered by scientists. The new finding




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Spina Bifida Surgery Before Birth can Restore Brain Structure

Fetal surgery to correct congenital spinal cord defects is more effective at treating neurological structure than surgery after birth, reports a new study.




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Costa Rica: Restore fiscal sustainability and make growth more inclusive

Costa Rica has made impressive economic and social progress in recent years, with robust economic growth facilitating near-universal access to education, health care and pensions.




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More effort needed on government integrity to help restore public trust

Countries need to do more to identify and reduce conflicts of interest and other breaches of integrity to help win back trust in national governments, which surveys suggest remains below pre-crisis levels, according to a new OECD report.




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UK must tailor coronavirus action to restore faith

Britain has less margin for error because it is zigging to everyone else’s zag




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Trump offers U.S. support to France to help restore 'irreplaceable' Notre Dame after fire

The White House said 'we remember with grateful hearts the tolling of Notre Dame’s bells' in 2001 in 'recognition of the tragic September 11th attacks on American soil. Those bells will sound again.'




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Dillian Whyte should be restored as mandatory challenger for Deontay Wilder's WBC title: Eddie Hearn

Dillian Whyte should be immediately reinstated as mandatory challenger for the WBC heavyweight title after being cleared of doping, according to promoter Eddie Hearn. 




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Arsene Wenger hopes Mikel Arteta can restore Arsenal's 'culture in the way to play football' 

Arsene Wenger hopes that Mikel Arteta will be able to get Arsenal playing free-flowing football again. During the best parts of Wenger's tenure Arsenal were renowned for their attractive style of play.




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Boris Johnson restores the Tory whip to 10 Brexit rebels

Boris Johnson has restored the Tory whip to 10 of the 21 former Conservative rebels who were expelled after backing a bid to block a No Deal Brexit.




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Digital wizardry restores some of Europe's most stunning castles to their former glory

Seven of Europe's most impressive ruined castles have been given an extreme makeover. They have been 'rebuilt' by a team of designers and architects.




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Norton Motorcycles 'will be restored to former glory', says new owner

India's TVS Motor, which bought the British brand out of administration for £16m earlier this month, is reportedly set to invest tens of millions of pounds in the luxury motorbike maker.




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MIDAS SHARE TIPS: Restore could earn a you a bomb!

In the 1936, the War Office turned a disused mine into an underground weapons store. In 2008 it was acquired by Restore, which is now the second largest data storage firm in Britain.




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Pvt mobile phones restored in Kashmir; situation remains calm

Private cell phone operators resumed their services but mobile Internet continued to remain suspended on Saturday in the Kashmir valley, a move taken as a precautionary step after the killing of self-styled local chief of banned Hizbul Mujahdieen, Reyaz Naikoo, earlier this week. The situation in the valley, which has been witnessing lockdown since the third week of March due to COVID-19 pandemic, was generally calm barring a few local protests in some villages of Pulwama in south Kashmir. Seeing an improvement of the situation after Naikoo was killed in an encounter with security forces on Wednesday, the authorities allowed private telecom operators to resume their services from Friday night but asked them to keep Internet connection barred. Restrictions had been imposed in the valley after the death of Naikoo and additional paramilitary forces were deployed at vulnerable points to prevent any mischief or stone pelting. SMS services have been snapped across all telecom operators till




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Founders would have wanted inheritance tax restored


Given our Constitutional mandate to "endeavour to eliminate inequalities in status, facilities and opportunities," Shankar Jaganathan explains why reintroduction of the Inheritance Tax may be a step worthy of serious consideration.




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Restored from the ruins


A South Marathwada village reconstructs itself after the devastating earthquake, with help from Jnana Prabodhini. Sayli Udas reports.




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MSMEs demand big-ticket package to restore biz




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Barring Pulwama, Mobile Phone Services Restored After 3 Days in Kashmir

Subscribers of BSNL postpaid services complained that SMS facility which was suspended on May 6, has still not been restored.




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Private Mobile Phone Services Restored in Kashmir, Situation Remains Calm

Seeing an improvement of the situation, the authorities allowed private telecom operators to resume their services from Friday night but asked them to keep Internet connection barred.




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Mobile phone services restored in Kashmir

The mobile phone services have been restored across the Kashmir valley, they said, adding the decision was taken in view of the improving situation.




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The free-market family : how the market crushed the American dream (and how it can be restored) [Electronic book] / Maxine Eichner.

New York, NY : Oxford University Press, 2020.




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Predatory value extraction: how the looting of the business corporation became the U.S. norm and how sustainable prosperity can be restored / William Lazonick and Jang-Sup Shin

Dewey Library - HB201.L39 2020




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Livemarks restores Live Bookmarks support in Firefox

Live Bookmarks combines Firefoxs bookmarking functionality with the dynamic nature of RSS feeds to create auto-updating bookmark folders that list all recent entries from RSS feeds.

The removal causes quite the issues for users who make use of the feature. Mozilla announced that it plans to export the list of feeds to an OPML file which the majority of RSS readers support.

While there are some alternatives that might work for some users, there was not a real solution to regain the functionality once it is removed.

complete article




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An Organized Piano Restored

A new blog launching March 3 follows the restorative conservation of a rare survival: an organized piano. A piano combined with a pipe organ, this unique instrument towered at nine feet tall and seven feet wide. Its restoration raises questions at every step. Repairing a broken element could mean erasing a piece of the object’s […]