Background:

The Center to Reduce Cancer Health Disparities (CRCHD), NCI, implemented Screen to Save, NCI's Colorectal Cancer Outreach and Screening Initiative to promote awareness and knowledge of colorectal cancer in racial/ethnic and rural populations.

It is well established that African Americans exhibit higher incidence, higher mortality, and more aggressive forms of some cancers, including those of breast, prostate, colon, stomach, and cervix. Here we examine the ancestral haplotype of the TRPV6 calcium channel as a putative genomic factor in this racial divide. The minor (ancestral) allele frequency is 60% in people of African ancestry, but between 1% and 11% in all other populations. Research on TRPV6 structure/function, its association with specific cancers, and the evolutionary-ecological conditions that impacted selection of its haplotypes are synthesized to provide evidence for TRPV6 as a germline susceptibility locus in cancer. Recently elucidated mechanisms of TRPV6 channel deactivation are discussed in relation to the location of the allele favored in selection, suggesting a reduced capacity to inactivate the channel in those who have the ancestral haplotype. This could result in an excessively high cellular Ca²⁺, which has been implicated in cancer, for those in settings where calcium intake is far higher than in their ancestral environment. A recent report associating increasing calcium intake with a pattern of increase in aggressive prostate cancer in African-American but not European-American men may be related. If TRPV6 is found to be associated with cancer, further research would be warranted to improve risk assessment and examine interventions with the aim of improving cancer outcomes for people of African ancestry.

More than 20 million Americans lost their jobs in the last month, and unemployment among African-Americans has hit 16.7 percent.

Many people saw more than the last moments of Ahmaud Arbery's life when a video emerged this week of white men armed with guns confronting the black man, a struggle with punches thrown, three shots fired and Arbery collapsing dead. The Feb. 23 shooting in coastal Georgia is drawing comparisons to a much darker period of U.S. history — when extrajudicial killings of black people, almost exclusively at the hands of white male vigilantes, inflicted racial terror on African Americans. It frequently happened with law enforcement complicity or feigned ignorance.

NSW's Law Enforcement Conduct Commission recommends disciplinary action be taken against two police officers who engaged in misconduct by racially abusing two Afghan women at a traffic stop in Western Sydney.

'I want to see every community treated fairly,' NYC Mayor Bill de Blasio says

A study at Columbia University Mailman School of Public Health found that black subjects who were exposed to highly segregated neighborhoods in young adulthood exhibited worse performance in cognitive skills in mid-life. This outcome may explain black-white disparities in dementia risk at older age.

Reports of interference with aircraft radio communications at one of regional Victoria's busiest airports, where a flying school training pilots for Chinese airlines has been operating for about a year, are being investigated.

Members of the Energy and Commerce Committee’s Health and Oversight and Investigations subcommittees today held a bipartisan teleconference forum with Centers for Disease Control and Prevention (CDC) Principal Deputy Director Anne Schuchat, M.D., to discuss racial disparities in health outcomes for COVID-19 patients. Health Subcommittee Chairwoman Anna G. Eshoo (D-CA), Health Subcommittee Ranking Member Michael C. Burgess, M.D. (R-TX), Oversight and Investigations Subcommittee Chair Diana DeGette (D-CO) and Oversight and Investigations Subcommittee Ranking Member Brett Guthrie (R-KY) released a joint statement following the call: “Today, bipartisan members of our two subcommittees discussed the deeply troubling racial disparities in health outcomes for COVID-19 patients with CDC’s Principal Deputy Director Schuchat.  During the call, members received an update on CDC’s COVID-19 response, current data collection efforts, and reiterated the need for more accurate and timely demographic data.  “Congress stands ready to work with the CDC to secure comprehensive demographic data to help us direct resources and support to close this gap in these health outcomes.” ###

Three individuals were indicted today by a federal grand jury in the District of Massachusetts for conspiring to interfere with the civil rights of members of the Macedonia Church of God in Christ, a Springfield, Mass., church with a predominantly African-American congregation.

Four individuals have been arrested and charged with carrying out a racially-motivated beating and conspiring to interfere with the civil rights of an African-American man in Nampa, Idaho.

The Department today filed a lawsuit against the former owner and managers of Homestead Mobile Home Village, a mobile home park in Gulfport, Miss., for violating the Fair Housing Act by discriminating against black tenants on the basis of race or color.

The Department filed a lawsuit against the owner and employees of Rolling Oaks Apartments, a 72-unit complex in Clanton, Ala., for violating the Fair Housing Act by discriminating on the basis of race or color in the rental of apartments. The lawsuit, filed in the U.S. District Court for the Middle District of Alabama, alleges that the employees, Kenneth R. Scott and Frankie L. Roberson, told white testers that a selling point of Rolling Oaks Apartments was the lack of African American tenants and that they had adopted rental policies intended to discourage African American rental applicants.

The Department filed a lawsuit against the owner and property manager of a 48-unit apartment complex in Ann Arbor, Mich., alleging that the defendants discriminated on the basis of race or color in the rental of apartments.

A federal grand jury in the District of Massachusetts has charged Michael Jacques and Thomas Gleason of Springfield, Mass., in a three-count superseding indictment in relation to the arson of a church.

The Department has reached a consent decree with the township of Green Brook, N.J., that, if approved by the U.S. District Court for the District of New Jersey, will resolve the department’s lawsuit against Green Brook alleging racial discrimination in employment in violation of Title VII of the Civil Rights Act of 1964, as amended.

The owners and operators of Ivanhoe House Apartments, an apartment complex in Ann Arbor, Mich., have agreed to pay $82,500 to settle a lawsuit filed by the Justice Department alleging that they had discriminated against African-American home-seekers, in violation of the Fair Housing Act.

The government’s lawsuit, filed on Oct. 15, 2009, alleged that former property manager Ann Wagner and former maintenance supervisor Corey Anderson created a racially hostile housing environment for one African-American family and two white families who associated with the African-American family while they were tenants at Lakeport Village.

Jason Barnwell, Gary Dodson,Jake Murphy and Dustin Hammond were indicted by a federal grand jury on civil rights charges and other federal charges stemming from their participation in an incident in January 2011 involving Molotov cocktails thrown at and into the home of a mixed-race couple living near Hardy, Ark.

Two Arkansas men pleaded guilty today in U.S. District Court in Little Rock, Ark., to charges related to their involvement in the firebombing of the house of an interracial couple.

The Justice Department announced today that Dale Mardis, 57, was sentenced today to life in prison, with no possibility of parole, for the racially-motivated killing of Shelby County, Tenn., Code Enforcement Officer Mickey Wright.

The Department of Justice today announced that it has entered into a settlement agreement with private plaintiffs and the Pickens County, Ala., Board of Education that requires the board to institute a series of educational reforms designed to eliminate the remaining vestiges of its formerly segregated school system.

Paul Beebe and Jesse Sanford of Farmington, N.M., pleaded guilty today in U.S. District Court in Albuquerque, N.M., to federal hate crime charges related to a racially-motivated assault on a 22-year-old developmentally disabled man of Navajo descent.

Zachary Beck was sentenced to 51 months in prison for civil rights crimes related to his participation in a racially-motivated attack on an African-American man in Vancouver, Wash., in January 2010.

The Department of Justice announced today the filing of a lawsuit against the Texas Department of Family and Protective Services, alleging the agency discriminated against a black male former employee on the basis of race and/or sex by subjecting him to a hostile work environment and then terminating him in violation of Title VII of the Civil Rights Act of 1964, as amended.

The Justice Department has filed a lawsuit against the owners of Yorkshire Apartments, Thackeray Ledges and Wales Ridge Apartments in Massillon, Ohio, for discriminating on the basis of race and familial status when renting their apartments in violation of the Fair Housing Act.

Today, the Departments of Justice and Education released two new guidance documents ¨C one for school districts and one for colleges and universities ¨C detailing the flexibility that the Supreme Court has provided to educational institutions to promote diversity and, in the case of elementary and secondary schools, reduce racial isolation among students within the confines of the law.

Gary Dodson, 32, of Waldron, Ark., pleaded guilty today in U.S. District Court in Little Rock, Ark., to one count of civil rights conspiracy, one count of interference with housing rights due to race and one count of possession of an unregistered firearm/destructive device for his involvement in the Jan. 14, 2011, racially motivated firebombing of the home of an interracial couple in Hardy, Ark.

Paul Beebe and Jesse Sanford of Farmington, N.M., were sentenced today in U.S. District Court in Santa Fe, N.M., on federal hate crime charges related to a racially-motivated assault on a 22-year-old developmentally disabled man of Navajo descent.

Barnwell, 37, of Evening Shade, Ark., was sentenced in Little Rock, Ark., for his involvement in firebombing the residence of an interracial couple.

The Justice Department announced today that Ross Hack, 40, Leland Jones, 31, and Melissa Hack, 37, have been charged with first degree murder and firearms offenses in relation to the 1998 deaths of Lin Newborn and Daniel Shersty.

The Justice Department announced today that Charles Wilhelm, 23, of Independence, Mo., pleaded guilty in U.S. District Court in Kansas City, Mo., to federal hate crime charges in connection with the vandalism and arson of a bi-racial man’s home in 2006.

Deryl Paul Dedmon, John Aaron Rice and Dylan Wade Butler, all from Brandon, Miss., pleaded guilty today in U.S. District Court in Jackson to federal hate crime charges in connection with an assault culminating in the death of James Craig Anderson.

The Department of Justice announced today that Gary Dodson, 33, of Waldron, Ark., was sentenced in Little Rock for his involvement in firebombing the residence of an interracial couple. On Dec. 7, 2011, Dodson pleaded guilty to conspiring to violate the civil rights, criminal interference with housing rights due to race and possession of an unregistered firearm/destructive device. District Judge Billy Roy Wilson sentenced Dodson to 15 years in prison and 3 years of supervised release for the three counts of conviction.

A Missouri woman was sentenced today to 63 months in prison for her role in the vandalism and arson of a biracial man’s home in Independence, Mo., the Department of Justice announced.

Charles Wilhelm, 23, of Independence, was sentenced in the Western District of Missouri by U.S. District Judge Dean Whipple.

A Missouri man was sentenced today to 30 months in prison for his role in the vandalism and arson of a biracial man’s home in Independence, Mo., the Department of Justice announced.

The Justice Department announced that it has entered into a settlement agreement with the Northeastern Local School District in Springfield and South Vienna, Ohio, to resolve allegations of racial harassment of African-American students in the district. The district serves approximately 3,700 students, less than two percent of whom are African-American.

The Justice Department announced that, jointly with the Meridian Public School District in Meridian, Miss., and private plaintiffs, it has filed a landmark consent decree to prevent and address racial discrimination in student discipline in district schools.

The Department of Justice today announced that a federal grand jury sitting in Seattle has indicted Jamie Larson, 49, on a federal hate crime charge relating to a racially-motivated assault of a 50-year-old Sikh man.

The U.S. District Court for the Southern District of Mississippi today approved a landmark consent decree filed by the Justice Department, together with private plaintiffs and the Meridian Public School District in Meridian, Miss., to prevent and address racial discrimination in student discipline

Jonathan Caine, 20, of Nashville, Tenn., pleaded guilty today to a federal hate crime for making racially motivated threats to an African-American assistant football coach at a local high school in, the Justice Department announced.

Thomas Windell Smith, 24, of Dothan, Ala., turned himself in and pleaded guilty in federal court on Friday, Dec. 6, 2013, to one count of conspiring to violate housing rights, the Justice Department announced today.

Acting Assistant Attorney General Jocelyn Samuels for the Civil Rights Division and U.S. Attorney Tammy Dickinson for the Western District of Missouri announced that a man and a woman, both from Independence, Mo., were sentenced in federal court today for violating the civil rights of an African-American family by setting fire to their residence.

Anthony Merrell Tyler, 33, pleaded guilty in federal court today to violating the Matthew Shepard and James Byrd Jr. Hate Crimes Prevention Act for his role in a 2011 racially motivated attack on a white man and an African-American woman in Marysville, Calif.

Billy James Hammett, 30, of Marysville, Calif., was sentenced today by U.S. District Judge John A. Mendez to serve 87 months in prison for violating the Matthew Shepard and James Byrd Jr. Hate Crimes Prevention Act in a 2011 racially motivated attack against a white man and an African-American woman in Marysville.

An information was filed charging Robert Keller, 70, with interfering with the housing rights of three members of an interracial family because of the family members’ races and because the family members were living in Hurricane, Utah.

Noting that African-American and Hispanic males are arrested at disproportionately high rates, U.S. Attorney General Eric Holder said Monday that the Justice Department will seek to collect data about stops, searches and arrests as part of a larger effort to analyze and reduce the possible effect of bias within the criminal justice system.