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AG Jennings Sues Amazon For Illegally Maintaining Monopoly Power

Attorney General Jennings yesterday joined the Federal Trade Commission and 16 other state attorneys general to sue Amazon.com, Inc. alleging that the online retail and technology company is a monopolist that uses a set of interlocking anticompetitive and unfair strategies to illegally maintain its monopoly power. The FTC and its state partners say Amazon’s actions […]



  • Department of Justice Press Releases
  • Fraud

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Patent Monopolies Driving High U.S. Drug Prices: Study

Title: Patent Monopolies Driving High U.S. Drug Prices: Study
Category: Health News
Created: 8/23/2016 12:00:00 AM
Last Editorial Review: 8/24/2016 12:00:00 AM




mono

More Evidence Links the 'Mono' Virus to MS Risk

Title: More Evidence Links the 'Mono' Virus to MS Risk
Category: Health News
Created: 8/30/2017 12:00:00 AM
Last Editorial Review: 8/31/2017 12:00:00 AM




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lncRNA BC200 is processed into a stable Alu monomer [ARTICLE]

The noncoding RNA BC200 is elevated in human cancers and is implicated in translation regulation as well as cell survival and proliferation. Upon BC200 overexpression, we observed correlated expression of a second, smaller RNA species. This RNA is expressed endogenously and exhibits cell-type-dependent variability relative to BC200. Aptamer-tagged expression constructs confirmed that the RNA is a truncated form of BC200, and sequencing revealed a modal length of 120 nt; thus, we refer to the RNA fragment as BC120. We present a methodology for accurate and specific detection of BC120 and establish that BC120 is expressed in several normal human tissues and is also elevated in ovarian cancer. BC120 exhibits remarkable stability relative to BC200 and is resistant to knockdown strategies that target the 3' unique sequence of BC200. Combined knockdown of BC200 and BC120 exhibits greater phenotypic impacts than knockdown of BC200 alone, and overexpression of BC120 negatively impacts translation of a GFP reporter, providing insight into a potential translational regulatory role for this RNA. The presence of a novel, truncated, and stable form of BC200 adds complexity to the investigation of this noncoding RNA that must be considered in future studies of BC200 and other related Alu RNAs.




mono

The Team Behind Heretic Talks That Ending, The Book of Mormon, and Monopoly



Writer-director partners Scott Beck and Bryan Woods dive into the biggest spoilers of their new Hugh Grant thriller.








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Are Monoclonal Antibodies Effective in Treating High Cholesterol?

Monoclonal antibodies are the antibodies produced in the laboratory which can increase, copy, or restore the immune system's response to certain antigens.




mono

Monoclonal Antibodies: Revolutionizing Drug Therapies

Monoclonal antibodies (mAbs) are special proteins used to help prevent, detect, and treat a wide range of diseases, both infectious and non-infectious.




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Raai Laxmi aka Lakshmi Rai's Hot looks in in White monokini

Raai Laxmi, who was earlier called as Lakshmi Rai, raises the temperature in white monokini.




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Monogoto, an innovator in ‘connectivity as a service,’ raises $27M

Connectivity and connected networks are part and parcel of the way many devices and services operate today, thanks to innovations and expansions in mobile networks, on-device processing, and the cloud. But behind the scenes, there remains a lot of fragmentation: Different regions, technologies, tariffs, and devices can spell a lot of work for enterprises or service […]

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mono

Revealing the effect of host–guest complementarity in supramolecular monofunctional platinum(II) drugs

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02012J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Shib Shankar Paul, Jan Novotný, Jakub Jakubec, Kateřina Petrláková, Pia Jurček, Klára Rašková, Michaela Kuchynka, Michal Masařík, Petr Kulhánek, Radek Marek
Host–guest complementarity is shown to influence the chemical activation by aquation and the biological activity of platinum(II) drugs.
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mono

Detection and Identification of Single Ribonucleotide Monophosphates using a Dual In-Plane Nanopore Sensor Made from a Thermoplastic via Replication

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC01062G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Steven A. Soper, Chathurika Rathnayaka, Indu Chandrasoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Collin J McKinney, Matthew David Verber, Sunggook Park
We report the generation of ~8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served...
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mono

Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00016A, Paper
Ethan J. Lockhart, Lisa F. Horowitz, Adán Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert Folch
A microfluidic platform was developed that hydrodynamically traps microdissected cuboids for selective drug treatments and isolates conditions with thermoplastic valves.
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mono

Capillary imbibition of confined monodisperse emulsions in microfluidic channels

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00179F, Paper
Masoud Norouzi Darabad, Sagnik Singha, Siva A. Vanapalli, Mark W. Vaughn, Jerzy Blawzdziewicz
Emulsion imbibition into flat capillaries is very complex. We show that formation of a clear-fluid or dense-emulsion region behind the meniscus, concentration and velocity fluctuations, and generation of ordered domains are confinement controlled.
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mono

Effects of Monovalent and Divalent Cations on the Rheology of Entangled DNA

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D3SM00957B, Paper
Open Access
Jennifer Harnett, Simon Weir, Davide Michieletto
In this paper we investigate the effects of varying cation valency and concentration on the rheology of entangled Lambda DNA solutions. We show that monovalent cations moderately increase the viscoelasticty...
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mono

Grind, shine and detect: mechanochemical synthesis of AIE-active polyaromatic amide and its application as molecular receptor of monovalent anions or nucleotides

RSC Adv., 2024, 14,13227-13236
DOI: 10.1039/D4RA02129K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jakub S. Cyniak, Artur Kasprzak
The mechanochemical synthesis of AIE-active amide, as well as the application of the title compound as molecular receptor of monovalent anions and nucleotides, are described.
The content of this RSS Feed (c) The Royal Society of Chemistry




mono

A multi-channel microfluidic platform based on human flavin-containing monooxygenase 3 for personalised medicine

RSC Adv., 2024, 14,13209-13217
DOI: 10.1039/D4RA01516A, Paper
Open Access
Melissa De Angelis, Silvia Schobesberger, Florian Selinger, Viktor Laurin Sedlmayr, Martin Frauenlob, Orsola Corcione, Shiman Dong, Gianfranco Gilardi, Peter Ertl, Sheila J. Sadeghi
A microfluidic platform with immobilized human flavin-containing monooxygenase for high-throughput screening of drugs with relevance to personalised medicine.
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mono

Mesoporous degradable chitosan-based monoliths: synthesis and applications toward water purification

Mol. Syst. Des. Eng., 2024, 9,399-408
DOI: 10.1039/D3ME00180F, Paper
Jyoti Devi Katiyar, Subrata Chattopadhyay
A synthetic strategy is presented for the preparation of degradable chitosan based functional porous polymer monoliths with tunable surface area, which are capable to efficiently remove multiple pollutants from water.
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mono

The CF3TMS adduct of anthraquinone as a monomer for making polymers with potential as separation membranes

Polym. Chem., 2024, 15,4312-4318
DOI: 10.1039/D4PY01002G, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kim Jiayi Wu, John M. Tobin, Anli Ji, Yang Shi, Chunchun Ye, Gary S. Nichol, Alessio Fuoco, Mariagiulia Longo, Johannes C. Jansen, Neil B. McKeown
The CF3TMS adduct of anthraquinone reacts with diphenyl ether via a superacid-catalysed step-growth polymerisation to give a polymer (BTFMA-DPE) with promise for making gas separation membranes.
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mono

A novel amine-first strategy suitable for preparing both functional and engineering bio-polyamides: furfurylamine as the sole furan source for bisfuranic diamine/diacid monomers

Polym. Chem., 2024, 15,4433-4446
DOI: 10.1039/D4PY00567H, Paper
Hong-Hui Shu, Yun Liu, Sheng-Li Han, Xiu-Qin Fang, Chang Wang, Cheng-Mei Liu
Biomass-based polyamides (bioPAs) are renewable materials that are viable alternatives to petroleum-based polyamides in the engineering field.
The content of this RSS Feed (c) The Royal Society of Chemistry




mono

Fully Bio-Based Acetal Diepoxy Monomers: High Modulus, Good Thermal Stability and Readily Degradability

Polym. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4PY01038H, Paper
Zidie Song, Li Liu, Pengbo Zhang, Kangle Xue, Zibo Hua, Tao You, Yiqi Wu, Hong Cui, Zhen Hu, Yudong Huang
Degradable epoxy resins are designed to address the environmental pollution caused by traditional epoxy resins. However, incorporating the degradability of dynamic covalent bonds in the design of degradable resins often...
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mono

Acrylate–methacrylate radical copolymerization kinetics of sparingly water-soluble monomers in polar and nonpolar solvents

Polym. Chem., 2024, 15,4542-4553
DOI: 10.1039/D4PY01015A, Paper
Noushin Rajabalinia, Fatemeh Salarhosseini, Robin A. Hutchinson
The influence of solvent on radical copolymerization kinetics is studied to provide insight to emulsion polymerization systems.
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mono

Dibenzobarrelene-Derived Pd-NHCs: Efficient Precatalysts for the Suzuki-Miyaura Polycondensations of Dichloroarenes Monomers

Polym. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4PY01026D, Paper
Yuman Guo, Hao Wu, Meng-Jiao Zhang, Feng-Shou Liu
The Pd-catalyzed Suzuki-Miyaura polycondensations (SMPs) has emerged as a powerful method for synthesizing conjugated polymers (CPs). While numerous reports have utilized dibromoarene and diiodoarene derivatives as monomers, research on the...
The content of this RSS Feed (c) The Royal Society of Chemistry




mono

Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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mono

Bioinspired programmable coacervate droplets and self-assembled fibers through pH regulation of monomers

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01550A, Paper
Satyajit Patra, Sushmitha Chandrabhas, Subi J. George
Phase separation or phase transitions pervade the biological domain, where proteins and RNA engage in liquid-liquid phase separation (LLPS), forming liquid-like membraneless organelles. The misregulation or dysfunction of these proteins...
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mono

Exploring the valleytronic, optical, and piezoelectric properties of Janus MoBXY2 (X = N, P; Y = S, Se, Te) monolayers for multifunctional applications

Phys. Chem. Chem. Phys., 2024, Advance Article
DOI: 10.1039/D4CP03793F, Paper
Luogang Xie, Lingli Wang, YanDong Ma, Hongyan Lu, Yang Yang
Unveiling novel Janus MoBXY2 monolayers with unique valleytronic, optical, and piezoelectric properties for multifunctional applications.
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mono

Insight into the potential of M–NbS2 (M = Pd, Ti and V) monolayers as anode materials for alkali ion (Li/Na/K) batteries

Phys. Chem. Chem. Phys., 2024, Advance Article
DOI: 10.1039/D4CP03744H, Paper
Meixia Xiao, Shuling Xu, Haiyang Song, Zhifei Sun, Jiaying Bi, Beibei Xiao
First-principles calculations were conducted to explore the effects of Pd, Ti and V doping on the performance of NbS2 monolayers as electrode materials for alkali ion batteries.
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mono

Ballistic transport in sub-10 nm monolayer InAs transistors for high-performance applications

Phys. Chem. Chem. Phys., 2024, Advance Article
DOI: 10.1039/D4CP03789H, Paper
Tianruo Xie, Yuliang Mao
The modelling of double gate MOSFETs of monolayer InAsH2 is shown in (a). The corresponding transfer characteristics are shown for (b) n-type and (c) p-type, in which various doping concentrations are chosen.
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mono

High Chern number quantum anomalous Hall effect in monolayer Co3X3SSe (X = Sn, Pb) kagomes

Phys. Chem. Chem. Phys., 2024, Advance Article
DOI: 10.1039/D4CP03625E, Paper
Xiang Yin, Li Deng, Fei Wang, Yanzhao Wu, Junwei Tong, Xianmin Zhang
Two-dimensional stable kagome ferromagnets Co3Sn3SSe and Co3Pb3SSe can realize the QAHE with a high Chern number of |C| = 3, and present intriguing possibilities for advancing intrinsic high Chern number QAH devices.
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mono

Uniaxial Tensile Strain Impact on 1T-NbS2 Monolayers as Cathode Material for Lithium-Sulfur Batteries

Phys. Chem. Chem. Phys., 2024, Accepted Manuscript
DOI: 10.1039/D4CP03156C, Paper
Shanling Ren, Xiaocong Tan, Xin Huang, zhihong yang, Yunhui Wang
In this work, we report our study on asymmetrical Janus TiSSe monolayers as cathode materials for lithium-sulfur batteries by first-principles calculations, encompassing adsorption, catalytic, and conductive properties. The results indicate...
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Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Chem. Soc. Rev., 2024, 53,3714-3773
DOI: 10.1039/D3CS00921A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, Helena S. Azevedo
Self-assembled monolayers (SAMs) based on peptides represent a reproducible platform for screening and studying peptide functions and facilitating their translation into multidisciplinary applications.
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mono

Sulfonated hierarchical ZSM-5 zeolite monoliths as solid acid catalyst for esterification of oleic acid

Chem. Commun., 2024, 60,13356-13359
DOI: 10.1039/D4CC05044D, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Binhang Zhao, Pan Yang, Nan Zhang, Donald R. Inns, Elena F. Kozhevnikova, Alexandros P. Katsoulidis, Ivan V. Kozhevnikov, Alexander Steiner, Haifei Zhang
Sulfonated hierarchical H-ZSM-5 monoliths were synthesized via ice-templating as solid acid catalysts for biodiesel production.
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mono

Polarizable AMOEBA force field predicts thin and dense hydration layer around monosaccharides.

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC04415K, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Luke A Newman, Mackenzie G Patton, Breyanna A Rodriguez, Ethan W Sumner, Valerie Vaissier Welborn
Polarizable force fields crucially enhance the modeling of macromolecules in polar media. Here, we present new parameters to model six common monosaccharides with the polarizable AMOEBA force field. These parameters...
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mono

Base-Promoted Cascade 5-exo-dig Annulation/Carboxylation of o-(1-Alkynyl)benzenesulfonamides with CO2: Divergent Synthesis of Mono- or Gem-dicarboxylic Esters

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC05239K, Communication
Yang Yao, Junxue Bai, Peidong Cheng, Han Yang, Jianwei Sun, Song Sun
A base-promoted cascade 5-exo-dig cyclization/carboxylation of o-alkynylsulfamides with CO2 has been accomplished, furnishing a variety of benzosultams-containing acrylates in good yields by using CO2 as the carboxylic source. Notably, in...
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mono

Regulating the type of nitrogen to improve the performance of Co–N/C with a confinement effect in peroxymonosulfate activation for the effective degradation of organic pollutants

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D4EN00145A, Paper
Yanqing Cong, Lingjie Ye, Qiuang Zheng, Yudi Wang, Yifan Shao, Xuhua Ren, Shi-Wen Lv
Three Co–N/C-based catalysts with different types of nitrogen are prepared and employed to activate peroxymonosulfate for tetracycline degradation.
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mono

Selective metal recovery by mucin: turning gold from wastewater into a peroxymonosulfate-activated catalyst

Environ. Sci.: Nano, 2024, 11,1487-1498
DOI: 10.1039/D3EN00699A, Paper
Open Access
Shira Gavriely, Shachar Richter, Ines Zucker
This study explores mucin's ability to selectively recover gold (Au) from metal wastewater. The Au, in the form of a nanoparticle, was utilized in peroxymonosulfate activation for the degradation of bisphenol A.
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mono

Functionalized molybdenum disulfide (MoS2) monolayer as an efficient nanosensor towards toxic nitrogen containing gases

Environ. Sci.: Nano, 2024, 11,1740-1754
DOI: 10.1039/D4EN00072B, Paper
Wadha Alfalasi, Tanveer Hussain, Nacir Tit
Selective detection of toxic nitrogen-containing gases (e.g. NO and NO2) is achieved when special transition metal (TM) atoms are selected in doping molybdenum disulfide (MoS2) monolayer. The change of magnetic state is the secret of that selectivity.
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mono

Sulfur-doped porous carbon sheets embedded with rich iron sites for 1O2 dominated peroxymonosulfate activation

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D3EN00971H, Paper
Yadan Song, Yalong Liu, Yangju Li, Haipeng Hu, Kexin Huang, Zhe Zhang, Zhongxian Li, Wanning Cao, Kai Jiang, Dapeng Wu
Porous carbon films co-doped with iron, nitrogen, and sulfur were synthesized via a one-step pyrolysis process, which have multiple active sites and can produce bulk 1O2 through PMS activation, which is effective in phenol degradation.
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mono

Study on Raman scattering spectroscopy of Mn-doped GaN grown by the ammonothermal method

CrystEngComm, 2024, 26,2166-2171
DOI: 10.1039/D4CE00093E, Paper
Wenhao Lu, Tengkun Li, Guoqiang Ren, Zhenghui Xia, Kaihe Xie, Shaozhe Li, Liangkun Shen, Ke Xu
Mn-doped GaN crystals of a-plane and (11−22) plane were grown by the ammonothermal method.
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mono

On the mechanism of carboxylate elimination from carbohydrate monoester-derived radicals

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00241E, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Julia A. Turner, Hendrik Zipse, Mark S. Taylor
Computational analysis of the HAT-induced expulsion of carboxylic acids from monoacylated pyranosides implicates concerted elimination through a hydrogen-bonded transition state.
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mono

An efficient synthesis of mono-, di-, and tri-substituted 1,3-thiazoles employing functionalized thioamides as thiocarbonyl precursors

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00229F, Paper
Kalleshappa Sheela, Chikkappaiahnayaka Santhosh, Krishna Ravi Singh, Kalleshappa Sharath, Maralinganadoddi P. Sadashiva
Herein, we report an efficient strategy to synthesize functionalized 1,3-thiazoles using alkyl 2-amino-2-thioxoacetates.
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mono

Discovery of selective monosaccharide receptors via dynamic combinatorial chemistry

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00015C, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Miguel Alena-Rodriguez, Marcos Fernandez-Villamarin, Ignacio Alfonso, Paula M. Mendes
An effective workflow to discover selective saccharide receptors by combining dynamic combinatorial chemistry with isothermal titration calorimetry and NMR.
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mono

Stop abuse of patent monopolies in rare diseases, say patient representatives and treatment activists 

They seek urgent intervention by government, courts, and lawmakers into the issue  




mono

Intercluster charge ordering in monoclinic and triclinic Ba–Mo-based hollandite phases

Mater. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QM00622D, Research Article
Eslam M. Elbakry, Jared M. Allred
Reproducible synthesis of the three distinct crystal types of Mo-based hollandites. Metal–metal bond orders correlate to electron count per metal.
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mono

Instantaneous growth of single monolayers as the origin of spontaneous core–shell InxGa1−xN nanowires with bright red photoluminescence

Nanoscale Horiz., 2024, Advance Article
DOI: 10.1039/D4NH00412D, Communication
Vladimir G. Dubrovskii, George E. Cirlin, Demid A. Kirilenko, Konstantin P. Kotlyar, Ivan S. Makhov, Rodion R. Reznik, Vladislav O. Gridchin
We demonstrate spontaneous core–shell InxGa1−xN nanowires exhibiting bright photoluminescence at 650 nm. The surprising effect of material separation is attributed to the periodically changing environment for single monolayer growth.
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mono

A new concept for correction of instrumental isotopic fractionation in MC-ICP-MS using a pair of monoisotopic elements: a critical evaluation

J. Anal. At. Spectrom., 2024, Advance Article
DOI: 10.1039/D4JA00117F, Paper
Open Access
Andrii Tupys, Klaudia Tetfejer, Ludwik Halicz, Ewa Bulska, Jakub Karasiński
In this research work, we investigated the possibility of using mixtures of monoisotopic elements (93Nb/89Y, 165Ho/159Tb and 209Bi/197Au) as calibrators for accurate determination of isotope ratios by multicollector mass spectrometry (MC-ICP-MS).
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mono

A review on instability factors of mono- and divalent metal ion batteries: from fundamentals to approaches

J. Mater. Chem. A, 2024, 12,30190-30248
DOI: 10.1039/D4TA05386A, Review Article
Elmira Kohan, Roushan Khoshnavazi, Mir Ghasem Hosseini, Abdollah Salimi, Mehdi Salami-Kalajahi
Degradation phenomena in different components (cathode, anode, current collectors (CCs)) of mono- and divalent metal-based batteries affect their performance.
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