fitness Dynasty Fitness Unveils Their New Quick Release Barbell Collars By www.24-7pressrelease.com Published On :: Fri, 01 Sep 2017 07:00:00 GMT Weight lifting barbell clamps are easy to use and securely hold weights in place. Full Article
fitness Consumers Sit Down with Matt O'Brien from Niagara Hamilton Fitness Solutions By www.24-7pressrelease.com Published On :: Fri, 21 Sep 2018 07:00:00 GMT Niagara Hamilton Fitness Solutions is a company specialized in quality fitness equipment sales & service, servicing the Golden Horseshoe region. Niagara Hamilton Fitness Solutions wins this year its 1st Consumer Choice Award! Full Article
fitness "What the "BEEP?" fitcore5 Takes the Pain out of Fitness Testing (well, mostly): New App Makes Team Fitness Data Reporting More Reliable and Useful By www.24-7pressrelease.com Published On :: Thu, 18 Feb 2016 07:00:00 GMT An app designed for coaches to gather specific soccer fitness testing data, fitcore5 will help coaches and athletes gain a better understanding of their current fitness levels and establish clearer goals for improvement. Full Article
fitness Fighting Fibromyalgia & Fatigue with Cocolime Fitness By www.24-7pressrelease.com Published On :: Thu, 19 Apr 2018 07:00:00 GMT Developed by a fitness instructor coping with chronic pain & fatigue herself, Cocolime Fitness is bringing real relief to people around the world suffering with debilitating health issues. Full Article
fitness Residence Inn Times Square First Hotel in Manhattan to Offer PURE Fitness and Conference Space By www.24-7pressrelease.com Published On :: Thu, 28 Jun 2012 07:00:00 GMT The Residence Inn Times Square has announced that they are introducing Allergy Friendly Rooms, Fitness center and Conference Space. They're the first hotel in the Manhattan area to offer guests an Allergy Friendly Fitness center and Conference space. Full Article
fitness Fit Farm Donates $275,000.00 of Wellness & Fitness Gifts at the 2019 South Beach Wine & Food Festival By www.24-7pressrelease.com Published On :: Fri, 08 Mar 2019 07:00:00 GMT Fit Farm hosts individuals, groups, companies and fundraisers too … all are welcome. Now, with the nation's only permanent obstacle course with lodging, The Fit Farm Fury is a perfect turnkey solution for fundraising and corporate events. Full Article
fitness Fitness Vlogger, Katie, Chooses Pasture Raised Organic Eggs from Chino Valley Ranchers By www.24-7pressrelease.com Published On :: Fri, 15 Mar 2019 07:00:00 GMT Katie Yovin, a fitness and health video blogger, recently shared a video on why she only chooses Pasture-Raised Organic eggs from Chino Valley Ranchers. Full Article
fitness Fitness Coach Prefers Pasture Raised Eggs from Chino Valley Ranchers By www.24-7pressrelease.com Published On :: Fri, 29 Mar 2019 07:00:00 GMT Christopher Rocchio, a health and fitness coach from Southern California, recently shared the differences between caged eggs versus pasture raised eggs on his Instagram page. Full Article
fitness Brandon Schram Turned His Life Around Through Fitness and Wants To Help You Do the Same By www.24-7pressrelease.com Published On :: Thu, 10 Oct 2019 07:00:00 GMT Full Article
fitness Announcing RELARONE the Food Supplement that Promotes Quality of Life and Fitness By www.24-7pressrelease.com Published On :: Sun, 09 Feb 2020 07:00:00 GMT RELARONE is a dietary supplement for the purpose of helping people have a better quality of life and body care. Full Article
fitness Home-Bound Seniors Can Build Strength and Balance with Free Online Fitness Classes By www.24-7pressrelease.com Published On :: Fri, 17 Apr 2020 07:00:00 GMT Physical Therapist designed exercise program Full Article
fitness Gregory Lekhtman, Leading Inventor and Creator of Medical and Fitness Electronics & Products has been Recognized by the Top Professionals of North America - 2019-2020 Edition By www.24-7pressrelease.com Published On :: Wed, 27 Feb 2019 07:00:00 GMT Lekhtman holds degrees in Electrical Engineering (space cybernetics), Brain Research and Medical Electronics. He has received prestigious medals and diplomas from invention conventions held in USA, Geneva, Brussels, Germany, and Argentina. Full Article
fitness Famous Fitness Model and Nutritionist Rachel Scheer is Helping Thousands of Women Make Positive Lifelong Changes By www.24-7pressrelease.com Published On :: Tue, 18 Feb 2020 07:00:00 GMT Rachel quickly became a well-known successful fitness model and bikini competitor who has gained a worldwide reputation. Full Article
fitness National TV Personality and Fitness Trainer Eraldo Maglara Gets A New TV Show By www.24-7pressrelease.com Published On :: Wed, 10 Oct 2018 07:00:00 GMT New Program to Premier Oct. 13 on The CW Philly Full Article
fitness Aging Seniors Beat COVID-19 Isolation with Free Birdsong offer, Brain Fitness Games & Video Chat By www.24-7pressrelease.com Published On :: Tue, 31 Mar 2020 07:00:00 GMT Birdsong offers eight thousand unique, engaging content experiences, including video chat, music, classic tv shows, videos, travel, and fun brain fitness exercises and memory games. Full Article
fitness Belfast after-school coach running free fitness programmes for NI kids By www.belfastlive.co.uk Published On :: Thu, 7 May 2020 16:52:42 +0000 Paul has had the idea of taking his programmes online Full Article What's On
fitness Team-based fitness challenge system and method By www.freepatentsonline.com Published On :: Tue, 09 Dec 2014 08:00:00 EST A fitness challenge program designed to encourage physical activity as well as to entertain and engage participants. Individuals are organized into teams and compete individually as well as against other teams. The program incorporates the use of computer technology to record physical activity and track progress for individuals as well as their teams. The individual and team activity information is posted to a web site accessible to the participants. Each participant has an account and can access his or her activity data through the web site. Team progress can also be viewed in the form of activity level data as well as movement to various locations associated with activity levels. The program incorporates educational content that is tied to team progress in the challenge. The program may be organized and administered through the middle schools that student participants attend. Full Article
fitness CORE FITNESS SYSTEM By www.freepatentsonline.com Published On :: Thu, 15 Jun 2017 08:00:00 EDT A core fitness system for efficiently exercising the core muscles of a persons body. The system involves working a user's core muscles by rotating the user's body while holding the body at an angle. Full Article
fitness FITNESS SYSTEMS AND METHODS THEREOF By www.freepatentsonline.com Published On :: Thu, 15 Jun 2017 08:00:00 EDT Systems and methods for fitness tracking are provided. An exercise apparatus is in networked communication with a fitness tracking computing system. The configuration and location of movable components of the exercise apparatus is determined based on sensors. This information is provided to the fitness tracking computing system via networked communication. Full Article
fitness Remote Configuration and Operation of Fitness Studios from a Central Server By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A method for configuring and operating one or more fitness studios each comprising a plurality of exercise stations at which users perform associated exercise routines, each station having an associated display, the method comprising, for each fitness studio, periodically retrieving, by a server from a database, fitness information for the studio in question for a specified period, from a multi-period fitness library; communicating, by the server to a studio computer, the retrieved fitness information over a communications network; periodically receiving, by the studio computer, the retrieved fitness information; configuring the exercise stations dependent upon the received fitness information; and communicating, by the studio computer to the exercise station displays, dependent upon the received fitness information, station directions to users exercising at the stations for performing an exercise. Full Article
fitness WEIGHT LOADING SYSTEM FOR FITNESS EQUIPMENTS By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A weight loading system for fitness equipments includes a fitness equipment support, a rally rope, a motor, a motor driving and a motor control unit. The motor is a permanent magnet brushless DC motor with an external rotor structure, and the motor includes a stator mounted onto the fitness equipment support and an external rotor sheathed on the stator and rotatable with respect to the stator, and the rally rope is wound around the external rotor of the motor, and an end of the rally rope is coupled to the external rotor of the motor, and the other end of the rally rope is coupled to the power driving mechanism of the fitness equipment; the power driving mechanism is provided for driving the external rotor of the motor through the rally rope to rotate and generate a rally, and the motor control unit controls the motor to rotate in an opposite direction through the motor driving module, so as to produce a load force opposite to the rally. The weight loading system for fitness equipments structure is simple, lightweight, and achieves the effect of a stepless weight control. Full Article
fitness Spinning class fitness coaches back Daily Echo's Staying Alive campaign By www.dailyecho.co.uk Published On :: Mon, 24 Jun 2013 15:20:00 +0100 Active Nation fitness coaches at Chamberlayne Leisure Centre are supporting the Daily Echo’s Staying Alive campaign, urging Sotonians to burn off those extra calories in a bid to battle killer diseases and illnesses. Full Article
fitness Ten station fitness course will keep Southampton feeling fit By www.dailyecho.co.uk Published On :: Sat, 19 Jun 2010 10:23:53 +0100 A OUTDOOR trim trail to encourage Southampton residents to get fit has been launched at the city’s Sports Centre. Full Article
fitness Rising fitness a boost for women’s activewear sales By retail.economictimes.indiatimes.com Published On :: 2019-11-11T12:17:26+05:30 Women’s share in the activewear category has gone up for sports brands such as Nike, Reebok, Adidas and Puma because of an increase in their participation in sports and other activities such as running, yoga, pilates and Zumba. Full Article
fitness ‘Talwalkars to be Snap Fitness franchisees in 6 Asian countries outside India’ By retail.economictimes.indiatimes.com Published On :: 2017-07-11T15:16:00+05:30 The affordable gyms under Talwalkar-Snap Fitness tieup to open first in Singapore and Malaysia. Full Article
fitness New sensor could turn any clothing into fitness tracker By retail.economictimes.indiatimes.com Published On :: 2017-07-14T17:16:32+05:30 Researchers at Harvard University in the US created a highly sensitive soft capacitive sensor made of silicone and fabric that moves and flexes with the human body to unobtrusively and accurately detect movement. Full Article
fitness Fit and fine: Retail market for fitness in India likely to touch Rs 7,000cr by year-end By retail.economictimes.indiatimes.com Published On :: 2017-09-12T14:31:45+05:30 The value of the market in India is Rs 4,579 crore at present. Full Article
fitness Anytime fitness to invest Rs 10 cr for expansion By retail.economictimes.indiatimes.com Published On :: 2017-09-21T14:20:20+05:30 Anytime Fitness further eyes expansion in Tier II and III market. Full Article
fitness Fitness startup Curefit adds Rs 4.2 crore in cart By retail.economictimes.indiatimes.com Published On :: 2018-04-16T11:20:02+05:30 It secured Rs 4.18 crore in a funding round with participation from Flipkart cofounder Binny Bansal and Myntra-Jabong CEO Ananth Narayanan, according to data-intelligence platform Paper.vc. Full Article
fitness Mukesh Bansal’s Cure.fit acquires Fitness First chain By retail.economictimes.indiatimes.com Published On :: 2018-05-23T08:29:28+05:30 Full Article
fitness Mukesh Bansal's CureFit eyes 500 CultFit fitness centres by 2020 By retail.economictimes.indiatimes.com Published On :: 2018-08-27T18:08:30+05:30 Bansal said the startup has so far raised around $160 million and only less than 20% of the funds were utilised so far and the balance funds will be spent over the next few years towards developing fitness devices and technology platform, apart from expanding the footprint. Full Article
fitness Fitness fad boosts desi athleisure business By retail.economictimes.indiatimes.com Published On :: 2018-12-22T08:17:48+05:30 Some see it as fashion that is effortless and comfortable. While gym or performance wear is made mainly of polyester to ensure it dries quickly, athleisure wear is a combination of polyester and cotton. Full Article
fitness So finden Sie die richtige Fitness-Smartwatch By www.welt.de Published On :: Mon, 04 May 2020 09:23:00 GMT Eine Fitness-Smartwatch kann im Alltag sowie beim Sport nützlich sein – Features wie Herzfrequenz- und Schlafrhythmus-Messung, aber auch das Tracken von Schritten und verbrannten Kalorien können dabei helfen, gesünder zu leben. Full Article Webwelt & Technik
fitness Coronavirus pushed spin, barre, yoga and other fitness classes online. Here’s how Seattle-area fitness studios have adapted By www.seattletimes.com Published On :: Tue, 14 Apr 2020 06:00:32 -0700 In these coronavirus pandemic times, online yoga has become as ubiquitous as online dating. But for some other kinds of fitness classes, the switch to virtual instruction has been more challenging. Full Article Fitness Life Wellness
fitness Coronavirus pushed spin, barre, yoga and other fitness classes online. Here’s how Seattle-area fitness studios have adapted By www.seattletimes.com Published On :: Tue, 14 Apr 2020 06:00:32 -0700 In these coronavirus pandemic times, online yoga has become as ubiquitous as online dating. But for some other kinds of fitness classes, the switch to virtual instruction has been more challenging. Full Article Fitness Life Wellness
fitness What do zombies, puppies and hills have in common? They can all be part of your coronavirus-era fitness routine By www.seattletimes.com Published On :: Mon, 20 Apr 2020 06:00:02 -0700 So what if your gym is closed? There are lots of different ways to keep your fitness level up. Just look around your neighborhood and incorporate some of these fun little "games" into your workout routine. Full Article Fitness Life Lifestyle Outdoors
fitness Rowing machines the answer for grounded teens to maintain fitness, mental health By www.abc.net.au Published On :: Thu, 07 May 2020 18:59:12 +1000 Rowing machines and online coaching are keeping these teenage rowers motivated amid the coronavirus shutdown, and their coaches say many are even achieving personal best times. Full Article Rowing Sport - Leisure Youth Anxiety Regional
fitness Fitness and community helping mothers of Indigenous children to bridge cultural gap By www.abc.net.au Published On :: Sun, 22 Sep 2019 12:52:00 +1000 A group of mothers of Indigenous children is coming together in regional SA to create a cultural safe space and improve mental health in their community. Full Article ABC Riverland riverland Community and Society:All:All Community and Society:Family and Children:All Community and Society:Indigenous (Aboriginal and Torres Strait Islander):All Community and Society:Indigenous (Aboriginal and Torres Strait Islander):Indigenous Culture Health:Exercise and Fitness:All Health:Mental Health:All Australia:SA:Barmera 5345 Australia:SA:Berri 5343
fitness Could functional fitness trends like CrossFit and F45 become an Olympic sport? By www.abc.net.au Published On :: Sat, 03 Aug 2019 08:54:00 +1000 Paying money to see other people work out might not sound like everyone's idea of fun, but it is fast becoming a part of the international sporting calendar, and there's hope it will become part of a future Olympic Games. Full Article ABC Capricornia sydney capricornia southeastsa Arts and Entertainment:Kids Games and Links:Extreme Sports Health:Exercise and Fitness:All Health:Women's Health:All Lifestyle and Leisure:Clubs and Associations:All Sport:All:All Sport:Olympics (Summer):All Sport:Other Sports:All Sport:Sports Organisations:All Australia:All:All Australia:NSW:All Australia:NSW:Sydney 2000 Australia:QLD:All Australia:QLD:Gladstone 4680 Australia:SA:All Australia:SA:Mount Gambier 5290 Sweden:All:All United States:All:All
fitness Usain Bolt struggling with football fitness in bid to keep up with Central Coast Mariners By www.abc.net.au Published On :: Tue, 28 Aug 2018 21:19:00 +1000 It was plain to see Usain Bolt's second training session with the Central Coast Mariners was gruelling and that he was giving it his all but believe it or not, coach Mike Mulvey is asking him for more speed. Full Article ABC Radio Central Coast centralcoast Sport:All:All Sport:Soccer:All Australia:NSW:All Australia:NSW:Gosford 2250
fitness Lululemon Had the Nerve to Come for Beyoncé's Fitness Line By feeds.bet.com Published On :: Fri, 1 Apr 2016 15:00:00 EDT The BeyHive was having none of this. Full Article Beyhive Fashion and Beauty Beyonce
fitness Zeiko Lewis Featured In Club’s ‘Fitness Friday’ By bernews.com Published On :: Sun, 26 Apr 2020 11:46:37 +0000 Bermudian footballer Zeiko Lewis was recently featured on an episode of Charleston Battery’s ‘Fitness Friday,’ a series of videos showing some of the fitness routines undertaken by the club’s players. In the video, Lewis, along with teammate Robbie Crawford, execute several bodyweight holding exercises, including the high plank, side plank, bridge position, and the wall […](Click to read the full article) Full Article All Sports Videos #BermudaFootball #Fitness #SportsVideos #ZeikoLewis
fitness Photos: Caribbean Grand Prix Pro Fitness Show By bernews.com Published On :: Sun, 08 Dec 2019 16:32:27 +0000 The Caribbean Grand Prix Pro fitness show, with the IFFB Pro qualifier was held in the Ruth Seaton James Auditorium on Saturday [Dec 7] at CedarBridge Academy. Prejudging started at 10.00am and the main event competition got underway at 5.00pm. There was a Fitness Expo held throughout the day and night with multiple vendors on […](Click to read the full article) Full Article All News Photos Sports #BermudaBodybuilding #Fitness #GoodNews #SportsPhotos
fitness The Fitness Guru? By imeanwhat.com Published On :: Tue, 07 Apr 2020 13:48:47 +0000 The Fitness Guru? CHAPTER 6 – PART 1 THE FITNESS GURU? Losing a human being can be an exhilarating experience. Not an actual person such as a lover, friend or family member; that tends to be a sad affair, though not always. Losing enough excess fat that amounts to the weight of an entire human being, now that’s exhilarating. Such a loss—a person’s worth of blubber—referenced here, was something Abe Gurko was fortunate enough to experience. He attributed the unwanted amount of fat that he’d gained throughout his childhood to having been stuffed to the gills by an overly Jewish mother who survived I Mean…What?!? Full Article Breaking Newzzz Last Five Minutes of Fame fitness guru Los Angeles richard simmons Sharon Stone
fitness Bradley Simmonds' 20 minute workout will maintain your football fitness By www.bbc.co.uk Published On :: Thu, 07 May 2020 06:56:36 GMT Former footballer turned personal trainer Bradley Simmonds has designed 10 exercises that will help players of all levels keep in shape during lockdown. Full Article
fitness 10 of the best fitness trackers for monitoring heart rate By feedproxy.google.com Published On :: Sat, 27 Oct 2018 09:00:00 +0000 BEST FITNESS TRACKER DEALS: Fitbit - Charge 3 Activity Tracker + Heart Rate — $99.95 (save $30) Garmin - Forerunner 645 Music GPS Heart Rate Monitor Running Watch — $449.99 3Plus - HR Activity Tracker + Heart Rate — $49.99 Wellness is a buzzy word lately. Over the past few years, we’ve seen a surge in all things health, wellness, and spirituality. Juice bars are popping up, boutique studios are becoming more accessible, and essential oils are chilling us out. Self-care is becoming more of the norm too, but amidst all this hype, it can be challenging to find the right routine that promotes good exercise, sleep, vitals, and mindset. Read more...More about Apple Watch, Fitness Trackers, Smart Watch, Heart Rate Monitor, and Mashable Shopping IMAGE: Amazon BEST OVERALL Apple Watch Series 4 Take heart monitoring to the next level with the Apple Watch Series 4's amazing EKG feature and FDA-cleared precision. Warranty: 90 days with Apple Care+ Smartphone compatibility: Yes Battery life: 22 hours Weight: 1.06 oz What you'll get: A case, band, 1m magnetic charging cable, and 5W USB Power Adapter $236.98 from Amazon IMAGE: Amazon BEST BANG FOR YOUR BUCK Polar A370 Fitness Tracker Smartphone compatibility and a variety of wellness features makes Polar’s A370 Fitness Tracker our top choice for health management. Warranty: 2 years Smartphone Compatibility: Yes Battery life: 4 days Weight: 13.8 ounces What you’ll get: A Polar A370 Fitness Tracker, a band, a charging cable, and a manual $114.99 from Amazon IMAGE: Amazon EASIEST TO USE Fitbit Charge 3 Fitness Activity Tracker The new Charge 3 provides no-fuss wellness features to take your daily sleep, workouts, and vitals to the next level. Warranty: 45-day guarantee and 1 year warranty Smartphone compatibility: Yes Battery life: 7 days Weight: 4.8 ounces What you’ll get: A Fitbit Charge 3, classic wristbands (both small & large), and a charging cable $119.03 from Amazon IMAGE: Best Buy BEST FOR ATHLETES Garmin Forerunner 735XT Smartwatch With sport-specific settings, advanced training feedback, and a connected app, Garmin’s Forerunner 735XT Smartwatch is the perfect fitness companion for athletes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 1 day Weight: 1.4 ounces What you’ll get: A Garmin Forerunner 735XT Smartwatch, a charging/data clip, and a manual $349.99 from Best Buy IMAGE: Amazon BEST FOR TECH ENTHUSIASTS Nokia Steel HR Hybrid Smartwatch Add some tech to your exercise regimen with the Nokia’s Steel HR Hybrid with Alexa integration and three different heart monitor modes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 25 days Weight: 8.2 ounces What you’ll get: A Nokia Steel HR Hybrid Smartwatch and a CR2 battery $199.95 from Amazon IMAGE: Amazon BEST FOR WATER SPORTS Garmin vívoactive 3 Warranty: 1 year Smartphone compatibility: Yes Battery life: 10 days Weight: 1.44 ounces What you'll get: A vívoactive 3 Fitness Tracker, a charging/data cable, and manuals $319.99 from Amazon IMAGE: Amazon BEST FOR STYLE Motiv Ring Warranty: 45-day guarantee and 1-year warranty Smartphone compatibility: Yes Battery life: 3 days Weight: 1.6 ounces What you'll get: A Motiv Ring, sizing set, and two slim charging docks $199.99 from Amazon IMAGE: Amazon BUDGET PICK Microtella Fitness Tracker Microtella’s Fitness Tracker is affordable, monitors your heart rate, and comes with 14 different fitness settings for personalized workout stats. Warranty: None Smartphone Compatibility: Yes Battery life: 7 days Weight: 4 ounces What you’ll get: A Microtella Fitness Tracker, a band, and a USB charger $39.99 from Amazon IMAGE: Amazon BEST OF BOTH WORLDS Samsung Galaxy Fit The perfect midpoint between the Fitbit and Apple Watch, the Samsung Galaxy Fit is great for tracking your high-intensity activities and for managing your daily life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 7 days Weight: 3.2 ounces What you'll get: Samsung Galaxy Fit, charging cable, manuals $79 from Amazon IMAGE: Amazon BEST ON-SCREEN WORKOUTS Fitbit Versa The Fitbit Versa is best for those who need some extra guidance in the gym, and thanks to its comprehensive array of on-screen workouts, you'll get exactly that. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 4 days Weight: 5.12 ounces What you'll get: Fitbit Versa, charging cable, manuals $199.95 from Amazon IMAGE: Amazon BEST BATTERY LIFE Wahoo TICKR Won't take up precious real estate on your wrists and will provide personalized heart rate training, as well as an unbeatable 12-month battery life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 1 year Weight: 2.4 ounces What you'll get: Wahoo TICKR, battery, manuals $45.94 from Amazon Full Article Apple Watch Fitness Trackers Smart Watch Heart Rate Monitor Mashable Shopping
fitness On Beat Fitness is a dance party disguised as a workout for any quarantine mood By feedproxy.google.com Published On :: Sat, 09 May 2020 15:00:00 +0000 Work(out) From Home is a weekly column where we review smart fitness machines and apps in the wake of the coronavirus outbreak. Thanks to technology, there are still plenty of ways to exercise if your gym is closed. Read more... On Beat Fitness $120 (annual) View Product The Good Super fun workouts • Classes grouped by mood • Equipment-free workout options • Growing library of classes The Bad Lack of workout history • Expensive subscription • Inability to filter search The Bottom Line On Beat Fitness offers a variety of classes that cater to both your taste in music and your mood for the day. Not only are the workouts fun and effective, but exercising to the beat of the music makes it a lot easier to follow along. ⚡ Mashable Score 4.75 😎 Cool Factor 4.5 📘Learning Curve 5.0 💪Performance 5.0 💵Bang for the Buck 4.0 More about Apps, Fitness, Beauty, Fitness App, and Workout From Home Full Article Apps Fitness Beauty Fitness App Workout From Home
fitness Fitness freak promotes sperm smoothie By jamaica-star.com Published On :: Fri, 08 May 2020 05:01:30 -0500 Eyes popped and mouths dropped wide open this week when it was reported in this newspaper that a British woman is using sperm smoothies to build her immune system. Tracy Kiss, 32, said she takes the sperm straight from the source - her boyfriend... Full Article
fitness Coregulator Sin3a Promotes Postnatal Murine {beta}-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response By diabetes.diabetesjournals.org Published On :: 2020-04-21T12:16:29-07:00 Swi-independent 3a and 3b (Sin3a and Sin3b) are paralogous transcriptional coregulators that direct cellular differentiation, survival, and function. Here, we report that mouse Sin3a and Sin3b are co-produced in most pancreatic cells during embryogenesis but become much more enriched in endocrine cells in adults, implying continued essential roles in mature endocrine-cell function. Mice with loss of Sin3a in endocrine progenitors were normal during early postnatal stages but gradually developed diabetes before weaning. These physiological defects were preceded by the compromised survival, insulin-vesicle packaging, insulin secretion, and nutrient-induced Ca2+ influx of Sin3a-deficient β-cells. RNA-seq coupled with candidate chromatin-immunoprecipitation assays revealed several genes that could be directly regulated by Sin3a in β-cells, which modulate Ca2+/ion transport, cell survival, vesicle/membrane trafficking, glucose metabolism, and stress responses. Lastly, mice with loss of both Sin3a and Sin3b in multipotent embryonic pancreatic progenitors had significantly reduced islet-cell mass at birth, caused by decreased endocrine-progenitor production and increased β-cell death. These findings highlight the stage-specific requirements for the presumed "general" coregulators Sin3a and Sin3b in islet β-cells, with Sin3a being dispensable for differentiation but required for postnatal function and survival. Full Article
fitness Association of BMI, Fitness, and Mortality in Patients With Diabetes: Evaluating the Obesity Paradox in the Henry Ford Exercise Testing Project (FIT Project) Cohort By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE To determine the effect of fitness on the association between BMI and mortality among patients with diabetes. RESEARCH DESIGN AND METHODS We identified 8,528 patients with diabetes (self-report, medication use, or electronic medical record diagnosis) from the Henry Ford Exercise Testing Project (FIT Project). Patients with a BMI <18.5 kg/m2 or cancer were excluded. Fitness was measured as the METs achieved during a physician-referred treadmill stress test and categorized as low (<6), moderate (6–9.9), or high (≥10). Adjusted hazard ratios for mortality were calculated using standard BMI (kilograms per meter squared) cutoffs of normal (18.5–24.9), overweight (25–29.9), and obese (≥30). Adjusted splines centered at 22.5 kg/m2 were used to examine BMI as a continuous variable. RESULTS Patients had a mean age of 58 ± 11 years (49% women) with 1,319 deaths over a mean follow-up of 10.0 ± 4.1 years. Overall, obese patients had a 30% lower mortality hazard (P < 0.001) compared with normal-weight patients. In adjusted spline modeling, higher BMI as a continuous variable was predominantly associated with a lower mortality risk in the lowest fitness group and among patients with moderate fitness and BMI ≥30 kg/m2. Compared with the lowest fitness group, patients with higher fitness had an ~50% (6–9.9 METs) and 70% (≥10 METs) lower mortality hazard regardless of BMI (P < 0.001). CONCLUSIONS Among patients with diabetes, the obesity paradox was less pronounced for patients with the highest fitness level, and these patients also had the lowest risk of mortality. Full Article