Understanding the evolution of chromatin conformation among species is fundamental to elucidate the architecture and plasticity of genomes. Nonrandom interactions of linearly distant loci regulate gene function in species-specific patterns, affecting genome function, evolution, and, ultimately, speciation. Yet, data from nonmodel organisms are scarce. To capture the macroevolutionary diversity of vertebrate chromatin conformation, here we generate de novo genome assemblies for two cryptodiran (hidden-neck) turtles via Illumina sequencing, chromosome conformation capture, and RNA-seq: Apalone spinifera (ZZ/ZW, 2n = 66) and Staurotypus triporcatus (XX/XY, 2n = 54). We detected differences in the three-dimensional (3D) chromatin structure in turtles compared to other amniotes beyond the fusion/fission events detected in the linear genomes. Namely, whole-genome comparisons revealed distinct trends of chromosome rearrangements in turtles: (1) a low rate of genome reshuffling in Apalone (Trionychidae) whose karyotype is highly conserved when compared to chicken (likely ancestral for turtles), and (2) a moderate rate of fusions/fissions in Staurotypus (Kinosternidae) and Trachemys scripta (Emydidae). Furthermore, we identified a chromosome folding pattern that enables "centromere–telomere interactions" previously undetected in turtles. The combined turtle pattern of "centromere–telomere interactions" (discovered here) plus "centromere clustering" (previously reported in sauropsids) is novel for amniotes and it counters previous hypotheses about amniote 3D chromatin structure. We hypothesize that the divergent pattern found in turtles originated from an amniote ancestral state defined by a nuclear configuration with extensive associations among microchromosomes that were preserved upon the reshuffling of the linear genome.

Welcome challenger. Why not sit down, and play a little game?

Jessica Simpson sparked rumors this week with a cryptic post about making new music and having put up with "everything I did not deserve."

Le corps ligoté en état de décomposition retrouvé le 30 octobre dans l’un des parcs les plus achalandés de Montréal est celui de Kevin Mirshahi.

May 24, 2024

Quantum computers are probably coming—and when they arrive, they will, most likely, be able to break our standard public-key cryptography algorithms.

As the dust settles on a post-election stock market rally, some firms have already gained.

Antônio Vinicius Gritzbach had recently agreed to hand over information about the Primeiro Comando da Capital group.

The US Senate has approved the inclusion of new provisions in the bipartisan infrastructure bill to require intermediaries involved in cryptocurrency trading to report details about transactions.

Kajol took to her social media to talk about people taking therapy and how much they needed it; this has got netizens thinking about who she could be referring to.

Threat type: Ransomware

Aliases: Trojan-Ransom.FileCrypter (IKARUS)

Platforms: Windows

Overall Risk Rating: Low

Damage Potential: Medium

Distribution Potential: Low

Reported Infection: Low

Information Exposure: Low

Overview:

This Ransomware arrives on a system as a file dropped by other malware or as a file downloaded unknowingly by users when visiting malicious sites.

It terminates itself if it detects it is being run in a virtual environment.

The U.S. Energy Information Administration (EIA) is initiating a provisional survey of electricity consumption information from identified cryptocurrency mining companies operating in the United States.

MobileCoin, the startup known for building Signal’s crypto payments feature, has appointed a new CEO as it works on expanding its encrypted money transfer service to global users in need of a more modern remittance solution. Sara Drakeley is taking the helm as MobileCoin’s new chief executive officer. Replacing her previous role as the firm’s […]

© 2024 TechCrunch. All rights reserved. For personal use only.

This year’s Super Bowl drew advertisers willing to pay up to $7 million for a 30-second spot. WSJ advertising editor Suzanne Vranica and reporter Paul Vigna break down what to watch for from both new cryptocurrency brands and old regulars like Budweiser. Photo Illustration: Alexander Hotz/WSJ

Shiba Inu Coin’s recent surge, and subsequent fall in value, is part of a growing trend of meme coins that are rivaling some of the largest digital tokens in the world. WSJ retail investing reporter Caitlin McCabe explains why investors are pouring money into this meme based cryptocurrency. Photo: Amber Bragdon/Getty Images

Do terms like “nonfungible token,” “minting,” and “gas fees” sound like a foreign language to you? To better understand it -- and explain it -- WSJ’s Joanna Stern turned her son’s art into an NFT on the Ethereum blockchain. Photo illustration: Jacob Reynolds

Rupali Ganguly shared a cryptic post after filing a defamation notice against her stepdaughter, Esha Verma, seeking Rs 50 crore in damages for false claims about their relationship.

The crypto firm added that elevated interest rates, inflationary pressures, and tightening liquidity have created a more “cautious macroeconomic environment”

Bitcoin was inching towards its March 2024 all-time-high price of $73,750.07, but those whose crypto assets are locked with the WazirX exchange after a cyberattack are anxious about missing out

Most transactions in the financial system take place behind closed doors. Not so the bitcoin network, which runs on blockchain technology – on which transactions can actually be visualised. But what's the real deal when it comes to crypto? Is its vision of decentralisation and data integrity all its cracked up to be? Cathy Mulligan is a visiting researcher at Imperial College's Centre for Cryptocurrency Research and Engineering, and she's breaking down the blockchain hype and leading the dialogue on how businesses should use this technology. ABOUT WIRED SMARTER Experts and business leaders from the worlds of Energy, Money and Retail gathered at Kings Place, London, for WIRED Smarter on October 9, 2018. Discover some of the fascinating insights from speakers here: http://wired.uk/V29vMg ABOUT WIRED EVENTS WIRED events shine a spotlight on the innovators, inventors and entrepreneurs who are changing our world for the better. Explore this channel for videos showing on-stage talks, behind-the-scenes action, exclusive interviews and performances from our roster of events. Join us as we uncover the most relevant, up-and-coming trends and meet the people building the future. ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics. CONNECT WITH WIRED Web: http://po.st/WiredVideo Twitter: http://po.st/TwitterWired Facebook: http://po.st/FacebookWired Google+: http://po.st/GoogleWired Instagram: http://po.st/InstagramWired Magazine: http://po.st/MagazineWired Newsletter: http://po.st/NewslettersWired

On June 18, 2019, Facebook announced its virtual currency Libra. In Facebook’s vision, it should become a global currency for billions of people, especially those in developing countries who have no access to banks or financial services. In other words, Digital money which you can transfer to other people or simply use to buy stuff. But is it a true cryptocurrency and how will the world respond to a currency controlled by a group of mega-corporations? #facebook #libra #crypto

Ashley Tyson, spends her time aligning diverse teams, working on decentralized systems and supporting blockchain ecosystem initiatives like Ethereum Community Fund and ETHPrize. She is the Co-founder, Web3 Foundation and in this session from WIRED Smarter 2020, she shares a new way of thinking about the web exploring what a return to the original principles of the web looks like and how cryptocurrency can enable that. ABOUT WIRED SMARTER Curated by WIRED’s award-winning editorial team, WIRED Smarter gathers the disruptive minds across business, technology, retail, finance and politics to investigate how innovation, technological advances and world events are changing the way we interact with customers. CONNECT WITH WIRED Events: http://wired.uk/events Subscribe for Events Information: http://wired.uk/signup Web: http://bit.ly/VideoWired Twitter: http://bit.ly/TwitterWired Facebook: http://bit.ly/FacebookWired Instagram: http://bit.ly/InstagramWired Magazine: http://bit.ly/MagazineWired Newsletter: http://bit.ly/NewslettersWired

Produced by WIRED Brand Lab with AWS | Data security is top priority when building a product in its early stages, but not all software developers have expertise in it. The team at Evervault sought a solution and used AWS' Nitro Enclaves to create it. The result of this collaboration is Evervault Encryption Engine - or E3 - which provides highly constrained compute environments where sensitive data can be securely decrypted and processed. Since AWS and Nitro Enclaves are globally available on demand, Evervault easily provides affordable and secure encryption tools to developers everywhere, allowing for all software developers to ensure data security. 

National Bureau of Economic Research

National Bureau of Economic Research

IEEE / Institute of Electrical and Electronics Engineers Incorporated

IEEE / Institute of Electrical and Electronics Engineers Incorporated

The cryptocurrency climbed as much as 4.3 per cent to an unprecedented $79,771 on Sunday

A report by Chainalysis says India leads the world on global adoption index for crypto this year

The largest token climbed as much as 6.1 per cent on Sunday and extended gains to hit an unprecedented $82,300 on November 11

As money continues to pour into crypto following Donald Trump’s election victory, bitcoin has climbed to yet another record high

Bitcoin lags behind bonds, stocks and gold, signaling a possible slowdown in the crypto market

The European Union is working on new rules and controls that crypto companies will have to comply with

Celsius hopes that Bitcoin mining will help it repair its damaged relationship with customers, whose funds were frozen

Indian cryptocurrency exchanges will have to report suspicious activity to the Financial Intelligence Unit India

M2 crypto exchange said there had been a “cybersecurity incident involving $13.7 million, which was swiftly responded to”

WazirX proposed launching a decentralised exchange as well as a recovery token for outstanding debt settlement, as users are unable to access their existing crypto

Cryptocurrency investor Michael Terpin sued AT&T over a SIM card attack in 2018 that lost him control over $23 million. Now Bloomberg reports that he's suing the "15-year-old hacker and his crew of 'evil computer geniuses'" behind the attack. (Alternate source) Terpin, the founder and chief executive officer of blockchain advisory firm Transform Group, is suing Ellis Pinsky, now 18, for $71 million under a federal racketeering law that allows for triple damages. "Pinsky and his other cohorts are in fact evil computer geniuses with sociopathic traits who heartlessly ruin their innocent victims' lives and gleefully boast of their multi-million-dollar heists," Terpin said in his complaint filed Thursday in federal court in Manhattan. Pinsky, of Irvington, New York, couldn't be reached for comment.... According to Terpin. Pinsky's ring identifies people with large cryptocurrency holdings and gains control of their phones by bribing or fooling employees of their wireless carriers. The hackers are then able to intercept authentication messages, gain information and drain the victims' cryptocurrency accounts. Pinsky has boasted to friends that, starting at age 13, he stole more than $100 million worth of cryptocurrency, hundreds of thousands of dollars of which has been converted into cash stored in his bedroom, the lawsuit alleges. Terpin also claims that, after confronting Pinsky about his alleged role in the theft, the teenager sent him cryptocurrency, cash and a watch with a combined value of $2 million. He claims this was an admission by Pinsky that he had stolen from Terpin.

Read more of this story at Slashdot.

While this makes China the first country formalising digital currency—Bitcoin alternatives have existed for long now—it also sounds the bugle for other central banks to join the race.