4

Navratri 2024: 5 fasting rules for diabetics to ensure stable blood sugar levels

Here are five essential fasting rules to help maintain stable blood sugar levels during Navratri 2024.




4

Karwa Chauth 2024: 5 fasting tips for women with diabetes

Here are five fasting tips to help them manage diabetes effectively during Karwa Chauth 2024.




4

Diwali 2024: 5 must try sugar-free recipes for diabetics this Diwali

This Diwali, try these five delectable sugar-free recipes tailored for diabetics that allow you to enjoy the festival guilt-free!




4

Diwali 2024: How to get rid of acidity, bloating, constipation post Diwali binge?

Here are some natural ways to help ease digestive discomfort post-Diwali.




4

Andhra Pradesh Chief Minister lays foundation for three renewable energy projects with a total capacity of 5,314MW

A JV pact was also signed by the State power corporation and the National Hydropower Corporation for two pumped storage hydropower projects




4

Record breaking suspension of 146 MPs: Which States and parties affected most | Data

Tamil Nadu, Kerala, and West Bengal are most impacted by the suspensions




4

‘Abki Baar, 400 Paar’ slogan coined by public, not BJP: PM 

Mr. Modi says his ambition is not simply to form the government, but to make India the world’s third largest economy during his third term; slams Congress for destroying India’s manufacturing strength




4

Wayanad landslide: More than 1,000 government employees engaged in 24x7 relief operations, says CMO

The government staff are handling the coordination of the search and rescue effort, distribution of relief materials, counselling of landslide victims with medical conditions




4

People of Srinagar remain reluctant voters as district records 29.24% turnout

Srinagar district’s poll percentage was 27.9% in the 2014 Assembly election and recorded 29.24% this time; J&K Chief Electoral Officer says Srinagar saw an increase of 5% compared to voter turnout of the recent Lok Sabha polls



  • Jammu and Kashmir Assembly

4

ISSF Junior World Championship 2024: Pistol shooter Divanshi’s second gold leads India’s clean sweep 

India’s young shooters won five more medals, including two gold on October 4, taking the tally to 21 medals to remain at the top with 13 gold, two silver and six bronze




4

This Bengaluru software professional covered 518 km in three days to win Ultraman India 2024

Bengaluru’s Jayanarayan Raja won Ultraman India 2024, conquering 518 km in three days with a grueling swim, bike, and run challenge




4

Pakistan court gives 14-page questionnaire to Imran Khan, his wife Bushra Bibi in Al-Qadir Trust case

According to the NAB officials, the PTI founder and his wife obtained land worth billions of rupees from the property tycoon, to build an educational institute, called Al-Qadir University




4

Israeli strikes set off explosions in Beirut suburbs and kill 14 Palestinians in Gaza, medics say

The strike came hours after the Israeli military announced an expansion of the zone, where it has told Palestinians evacuating from other parts of Gaza to take refuge




4

Andhra Pradesh sets ambitious goals with Drone Policy 4.0

Approved by Council of Ministers, the policy aims to secure Rs. 1,000 crore in investments, generate employment for 40,000 people and create 25,000 skilled drone pilots; vision hinges on a planned 300-acre drone city at Orvakal in Kurnool district, the first-of-its-kind in the country




4

Weak dependence [electronic resource] : with examples and applications / by Jérôme Dedecker, Paul Doukhan, Gabriel Lang, León R. José Rafael, Sana Louhichi, Clémentine Prieur

New York, NY : Springer New York, 2007




4

P3MOT-decorated metal-porphyrin-based zirconium-MOF for the efficient electrochemical detection of 4-nitrobenzaldehyde

Anal. Methods, 2024, 16,2093-2100
DOI: 10.1039/D4AY00152D, Paper
Wen-yi Chen, Xin-yu Huang, Qian Sun, En-qing Gao
Developed a novel hybrid P3MOT@PCN-222(Fe) via in situ polymerization for 4-NBA detection. Showcased broad detection range, high sensitivity, selectivity and stability, laying groundwork for environmental monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

PCB-C4D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00198B, Paper
Mingpeng Yang, Mingyi Cao, Zhixuan Zhang, Chaofan Wang
A solution conductivity detection method, using PCB-C4D coupled with paper-based microfluidic sampling, has been proposed for the rapid and in situ analysis of raw solution with particle filtration, improving detection consistency and reliability.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42−

Anal. Methods, 2024, 16,2311-2321
DOI: 10.1039/D3AY01831H, Paper
Kang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei Wang
Based on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Construction of coumarin-appended calix[4]arene-based fluorescence sensor for the detection of carbofuran in cabbage

Anal. Methods, 2024, 16,2400-2411
DOI: 10.1039/D4AY00030G, Paper
Heni Soni, Nidhi Verma, Divyesh Y. Chaudhari, Sahaj A. Gandhi, Alok Pandya, Pinkesh G. Sutariya
This study presents a novel approach for the detection of carbofuran (CBF) insecticide by exploring a calix[4]arene-derived fluorescence probe, CouC4S, functionalized with two coumarin-labelled at the narrow edge of the calix[4]arene platform.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

​Healthy sign: On the voting in the 2024 J&K Assembly elections

Turnout numbers in the Assembly elections show distinct patterns in south Kashmir




4

​Regulation role: On the 2024 Medicine Nobel

The discovery of microRNA changed the understanding of gene regulation




4

Deep roots: On the 2024 Physics Nobel Prize 

Physics Nobel Prize acknowledges the diverse foundations of AI




4

​Against the odds: On the 2024 Haryana Assembly elections

The Congress could not counter the caste polarisation in Haryana 




4

​Respect the mandate: On the 2024 Jammu and Kashmir elections

With elections done and dusted, J&K now must return to statehood




4

A Korean win: On the 2024 Nobel Prize in Literature

A Nobel raises Korean prose to success levels of its drama and music 




4

​Sufferers, awarded: On the 2024 Nobel Peace Prize

The Nobel Peace for the selfless Nihon Hidankyo should help stir debates on nuclear disarmament




4

Fate of nations: On the 2024 Economics Nobel

The 2024 Nobel recognises the need for ‘inclusive’ institutions




4

Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus

RSC Med. Chem., 2024, 15,3395-3417
DOI: 10.1039/D4MD00334A, Research Article
Vu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh Thanh
D-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

RSC Med. Chem., 2024, 15,3495-3506
DOI: 10.1039/D4MD00275J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
The optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides

RSC Med. Chem., 2024, 15,3469-3476
DOI: 10.1039/D4MD00422A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hugo Kocek, Dominika Chalupská, Milan Dejmek, Alexandra Dvořáková, Michala Zgarbová, Michal Šála, Karel Chalupský, Petra Krafčíková, Tomáš Otava, Matúš Drexler, Eliška Procházková, Blanka Klepetářová, Milan Štefek, Ján Kozic, Helena Mertlíková-Kaiserová, Evzen Boura, Jan Weber, Radim Nencka
SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024)

RSC Med. Chem., 2024, 15,3371-3394
DOI: 10.1039/D4MD00384E, Review Article
Debasis Das, Lingzhi Xie, Jian Hong
Prospects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Design, synthesis, and structure–activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00537F, Research Article
Open Access
Abdelfattah Faouzi, Alexandre Arnaud, François Hallé, Jean Roussel, Mandy Aymard, Vincent Denavit, Cong Viet Do, Angélique Mularoni, Mohamed Salah, Ahmed ElHady, Thanh-Nhat Pham, Alexandre Bancet, Marc Le Borgne, Raphaël Terreux, Roland Barret, Matthias Engel, Thierry Lomberget
A series of sulfur-containing tetracycles was designed and evaluated for their ability to inhibit protein kinase DYRK1A, a target known to have several potential therapeutic applications including cancers, Down syndrome or Alzheimer's disease.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00663A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Václav Pflégr, Klára Konečná, Jiřina Stolaříková, Jan Ősterreicher, Ondřej Janďourek, Martin Krátký
Linking pyridine-4-carbohydrazide to other antimicrobial agents via oxocarboxylic acids significantly enhances efficacy against mycobacteria with promising selectivity and safety profiles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




4

3-Thio-3,4,5-Trisubstituted-1,2,4-Triazoles: High Affinity Somatostatin Receptor-4 Agonist Synthesis and Structure-Activity Relationships

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00597J, Research Article
Albert Michael Crider, Audrey Hospital, Karin Sandoval, William Neumann, Stephen Kukielski, Lejla Garic, Kristen Ingold, Matthew Dunahoo, Khush Srabony, Rafael Frare, Olivia Slater, Nathan Peel, Maria Kontoyianni, Ken Witt
Somatostatin receptor-4 (SST4) is a therapeutic target for several conditions, including Alzheimer’s disease, seizures, neuropsychiatric disorders, and pain. Our previous work on 1,2,4-triazole derivatives led to enhanced SST4 binding affinity,...
The content of this RSS Feed (c) The Royal Society of Chemistry




4

Water level in Mettur Dam stands at 107.04 feet




4

Tiruchi Today (November 7, 2024)




4

542: Breaking Up with CSS-in-JS, Mastodon, and Stories on the Web

We're talking CSS-in-JS, Token CSS, Matuzo being suspended from Twitter, trying out Mastodon, testing out stable diffusion, stories on the web, and Jake Albaugh's new social network.




4

543: Zach Leatherman on Eleventy, Mastodon, Twitter, and is-land

Zach Leatherman talks with us about what's new with Eleventy, setting up on Mastodon, what's happened with Twitter, and is-land.




4

544: Feedback, RSS Talk, Arc Brower, and Product Talk

Getting feedback for what you're building or writing, RSS feed reminiscing, Arc browser thoughts, products that didn't make that should have.




4

545: Arc Browser with Nate Parrott

Nate Parrott from The Browser Company of New York stops by to talk about Arc - including the history of Arc, how boosts work, building out dev features, how they deciding on what features to build, and feedback from Dave and Chris on Arc.




4

546: Ryan Dahl and Deno

Ryan Dahl stops by to talk about Node, Deno, JavaScript, testing, V8, and thoughts around getting started with Deno.




4

547: WordPress and GraphQL with Jason Bahl

Jason Bahl joins the show to talk about the GraphQL and WordPress connection, his work on WP GraphQL plugin, Faust and Atlas from WP Engine, Jamstack and Wordpress, and more.




4

548: Infinite Canvas, Luro + Figma, and Scraping or Crawling

What's going to happen to homework with AI? Thoughts on infinite canvas which leads into Luro and Sigma integration, and Chris gets nerdsniped and tries to scrap (or should he crawl?) websites for data.




4

549: Ben Ubois of Feedbin

Ben Ubois is the founder of Feedbin, the RSS reader of choice for Dave and Chris. What influenced the creation of Feedbin, the state of RSS in 2023, curating your RSS feed, and subscribing to newsletters in Feedbin.




4

554: Jamstack Thoughts with Brian Rinaldi

Brian Rinaldi joins us to talk about the state of Jamstack in 2023, acronym confusion, SPA confusion, developing common tools of understanding, why Netlify bought Gatsby, and the state of developer conferences.




4

564: Render ATL, New Colors Available, Gradients, HDR, and More

Chris previews a bit of his Render ATL 2023 talk, and then we mouth blog some color ideas, thoughts, and shame you for your non-HD websites.




4

574: Estelle & Eric on CSS The Definitive Guide, 5th Edition

Estelle Weyl and Eric Meyer join us to talk about the 5th edition of their book, CSS: The Definitive Guide. We talk about some of CSS' biggest blunders, custom scroll bars, single line comments, shorthand in CSS, useless CSS trivia, and how to get started learning CSS in 2023.




4

584: Community, Partnerships, Images, and Astro with Fred K. Schott

Fred K. Schott stops by to talk about building community, open source and sponsorship, building on partnerships in the dev community, WordPress + Astro, view transitions, using Discord for support, and leaking secret Astro Studio details.




4

594: Wiping Your Laptop, UX of Password Codes, and :Has Tips and Tricks

In this episode we're discussing making tech videos, website tinkering, :has tricks, SVG path commands, and the complexities of CSS & JavaScript logic.




4

597: How Many VS Code Plugins, Poor Charlie’s Almanack, and Where to Start in 2024?

We're closing in on episode 600 and need your help to celebrate! Listen in to learn how to contribute to the episode. We're also talking GitHub desktop apps and code editors, how many VS Code plugins are needed, reading long form like Poor Charlie's Almanack, InVision shutting down, and answering our first Q of the year: how would you approach learning web development in 2024?