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Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00432A, Paper
Peng-Fei Huang, Jia-Le Fu, Ying Peng, Jian-Hong Fan, Long-Jin Zhong, Kewen Tang, Yu Liu
2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent developments in the enzymatic modifications of steroid scaffolds

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00327F, Review Article
Open Access
Huibin Wang, Ikuro Abe
This review highlights the recent advancements in the enzymatic modifications of steroid scaffolds, emphasizing enzymatic hydroxylation, ketoreduction, dehydrogenation, enzymatic cascade reactions, and other modifications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Efficient synthesis of SCF3-containing 3-alkenylquinoxalinones via three-component radical cascade reaction

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00363B, Paper
Si-Yu Wang, Chu Liu, Wei Yang, Zhong-Ying Tian, Lin Yuan, Long-Yong Xie
A three-component cascade reaction of quinoxalinones, alkynes and AgSCF3 toward complete E-selective SCF3-containing 3-alkenylquinoxalinones was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tab Discarding in Chrome: a Memory-Saving Experiment




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Slots scarcity hits Indian airlines’ flight roadmap

The solution demands a comprehensive expansion of airside capacity across the country, but that has not materialised




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OpenAI builds first chip with Broadcom and TSMC, scales back foundry ambition

OpenAI is working with Broadcom and TSMC to build its first in-house chip designed to support its artificial intelligence systems, per sources




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'Scale at which this scam operates is shocking'

'There is an eminently fertile ground that perpetrators must be finding in our society.'




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Will Wim Wenders' Film Win An Oscar?

'This was a film, a story that had never been told before.'




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'Mom Was Very Scared Of...'

'When my mom saw my performance in Dhoka, she loved it.''She said, "I don't know why I stopped you for so many years. Ab jaa beta, jee le apni zindagi".'




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Shahana's Santosh Is UK's Oscar Choice!

'I'm there in every frame of this film.''The film is named after the character that I play.''It's about a feeling like you are capable of shouldering a film entirely on your own, which is a belief that I may not have in myself always.'




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Scaling Platforms Through Use Cases

New technology companies often have grand ambitions. And for good reasons - ambitious plans help recruit talent, raise capital, and set the bar high. But progress toward these high-level goals relies on identifying and excelling at much lower-level use cases.

It's very common for new technology companies to aspire being "the platform for... the Internet of things, AI analytics, mobile testing, etc." Being a platform means you capture a lot of uses cases or to put it more simply... people use your service for a lot of different things. And more use equals more value.

But vision is not the same as strategy. Vision is about the end goal. It paints a picture of the future state you're aiming for. It’s what you want to achieve. Strategy, on the other hand, is how you get there.

When you use a broad vision as a strategy, you end up having a hard time making decisions and rationalizing a never-ending set of opinions. With a strategy like “we’ll be the platform for the Internet of things”, everyone has an opinion on how things on the Internet should work -which one do we listen to?

Consider instead a specific market for the Internet of things, like home automation, and an even more specific use case for home automation like "controlling the temperature in your house". It's much easier to evaluate decisions about what a good experience for controlling the temperature in your house is than for "we’ll be the platform for the Internet of things”.

But if you focus on such a narrow use case, how will you ever build a big business? I'm not suggesting abandoning the big vision instead I'm advocating for having a strategy based on solving concrete uses cases to get there. Let's look at another example: Yelp.

Today, Yelp is used for recommendations for all kinds of services: skydiving training, auto body shops, tea parlors, and more. But it didn't start that way. Yes, Yelp likely started with the ambitious vision of being a platform for all service recommendations. But it first launched in San Francisco with restaurant reviews. A very specific market and very specific use case.

Why start with restaurants? A good starting use case is the one with the most acute pain. In the context of services, people need to eat three times a day. They get their hair cut once a month and maybe need a plumber once a year. So where should Yelp start? Probably restaurants.

When solving for a specific use case, it's important to build with the bigger vision in mind and not paint yourself into a corner of only being useful for one thing. But you definitely have to be great at solving each use case your platform supports. How else will you convince people to adopt your solution? Once you can demonstrate clear value for a specific use case, you can tackle more (likely adjacent ones).

This way of scaling ensures your solution is actually good at addressing a concrete problem people have not just an abstract vision. When you hear "What's your platform for? Well... you can use it for pretty much anything." in a sales pitch, that's a warning sign.

When you instead address specific use cases well, you learn what parts of your platform matter the most by identifying patterns and doubling down on them. It's only from solving highly specific use cases that you actually get to a platform that can be broadly used for many different things. And why Amazon started by only selling books on the Web.




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Helsinki: The Scandinavian design capital

If you love great design and architecture, Finland’s capital is right up your alley




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Life in a Jewish family : Edith Stein : an autobiography 1891-1916 / Sister Teresa Benedicta of the Cross Discalced Carmelite ; edited by Dr. L. Gelber and Romaeus Leuven, O.C.D. ; translation by Josephine Koeppel, O.C.D.

Washington, D.C. : ICS Publications, [2016]




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How the Natural History Museum is Scanning 80 Million Dead Creatures

The Natural History Museum in London has set itself the mammoth task of digitising its specimens - all 80 million of them. The museum's collection includes everything from a blue whale skeleton to Martian meteorites, making progress understandably slow. Head of Informatics Vince Smith says it would take around 1,500 years for the team to manually digitise it all, so in 2014 they decided to write software that allows them to do it in bulk. They now use six DSLR cameras to process up to 200 items at a time. WIRED went behind the scenes to meet the researchers working on the project and learn more about how they digitise the different specimens.




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Scaling for diversity with Google's Karina Govindji | WIRED Smarter

As the director for diversity, equity & inclusion EMEA at Google, Karina Govindji enables an environment of belonging for over 18,000 Googlers in 36 countries. At WIRED Smarter, Govindji explained how the tech giant built and actions its diversity programme. ABOUT WIRED SMARTER Curated by WIRED’s award-winning editorial team, WIRED Smarter gathers the disruptive minds across business, technology, retail, finance and politics to investigate how innovation, technological advances and world events are changing the way we interact with customers.




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Building out green energy on a global scale with Dale Vince | WIRED Smarter

Dale Vince, eco-warrior and founder of Ecotricity, the world’s first green energy company is on a mission to change the face of energy provision on a global scale and is a United Nations Climate Champion, he shared how at WIRED Smarter 2020. "With technology, we can stop using fossil fuels" ABOUT WIRED SMARTER Curated by WIRED’s award-winning editorial team, WIRED Smarter gathers the disruptive minds across business, technology, retail, finance and politics to investigate how innovation, technological advances and world events are changing the way we interact with customers. CONNECT WITH WIRED Events: http://wired.uk/events Subscribe for Events Information: http://wired.uk/signup Web: http://bit.ly/VideoWired Twitter: http://bit.ly/TwitterWired Facebook: http://bit.ly/FacebookWired Instagram: http://bit.ly/InstagramWired Magazine: http://bit.ly/MagazineWired Newsletter: http://bit.ly/NewslettersWired




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VFX Artist Breaks Down Oscar-Nominated CGI

The five films nominated for an Academy Award this year for visual effects were each selected for their own unique reasons. Kevin Baillie, a VFX artist who was worked on some of Hollywood's biggest movies, breaks down the visual effects in this year's Oscar nominees.




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How a NASCAR Pit Crew Perfects a Pit Stop

The seconds saved (and lost!) during a pit stop can be the difference between a champion and a racer who doesn't place. If we playback a video of a NASCAR pit crew, we can see all the things they do precisely in an incredibly short amount of time. *This video is about the 5 lug nut pit stop that is still used on the NASCAR Xfinity Series and the NASCAR Camping World truck Series. PIT Instruction and Training has trained pit crew athletes for the sport of NASCAR since 2001. With nearly 70% of its eight hundred and sixty-five students having raced in NASCAR’s top three divisions, PIT has proven itself to be a high capacity producer of pit crew talent for the motorsports industry. Interested in taking the pit crew path? Call 704-799-3869 or email pitcrew@visitpit.com for details on how to begin your new career in the pits. Adam Merrell has been coaching pit crews within NASCAR since 2006 and has coached multiple stock car and truck teams since joining PIT Instruction & Training in 2007. He is a certified and licensed athletic trainer (ATC/L), and a certified strength & conditioning coach (CSCS) by trade, which has strengthened his knowledge in biomechanics and coaching to help place pit crew members at the highest level with championship teams.




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Tech Support - Scam Fighters Answer Scam Questions From Twitter

Ashton Bingham and Art Kulik of Trilogy Media answer the internet's burning questions about scams. How do you protect your parents from scams? How do scammers get our phone numbers? Check out Art and Ashton's channel here: https://www.youtube.com/trilogymedia Director: Justin Wolfson Director of Photography: Corey Eisenstein Editor: Shandor Garrison Experts: Ashton Bingham & Art Kulik Producer: Justin Wolfson Associate Producer: Paul Gulyas Production Manager: Eric Martinez Production Coordinator: Fernando Davila Casting Producer or Talent Booker: Camera Operator: Brittany Berger Sound: Brett Van Deusen Production Assistant: Patrick Sargent Post Production Supervisor: Alexa Deutsch Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Assistant Editor: Ben Harowitz




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Tech Support - Lando Norris & Oscar Piastri Answer Formula 1 Questions From Twitter

Formula 1 drivers Lando Norris and Oscar Piastri of Team McLaren answer your questions about F1 racing from Twitter. What is the hardest track in F1? Why are drivers weighed before each race? How do drivers know it's time for a pit stop? Answers to these questions and many more await—it's Formula 1 Support.




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Tech Support - Scammer Payback Answers Scam Questions

Pierogi from Scammer Payback on YouTube joins WIRED to answer the internet's burning questions about scams and scambaiting. Why do scammers ask victims to buy gift cards? What are some of the biggest scammer red flags? Do they ever get caught? How many scams are out there? Should I mess with scammers for fun if I identify one? What software and hardware does Scammer Payback use? How can those creepy sex bot internet commenters lead to a scam? Pierogi answers these questions and many more on Scambaiting Support. Director: Lisandro Perez-Rey Director of Photography: Mark Denney Editor: Richard Trammell Expert: Pierogi Line Producer: Joseph Buscemi Associate Producer: Paul Gulyas Production Manager: Peter Brunette Production Coordinator: Rhyan Lark Talent Booker: Mica Medoff Camera Operator: Franz Criscione Sound Mixer: Mark Cochran Production Assistant: Reed Vrooman Post Production Supervisor: Christian Olguin Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Additional Editor: Paul Tael; Jason Malizia Assistant Editor: Billy Ward Special Thanks: The Entire Scammer Payback Team




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Correction: New horizons on advanced nanoscale materials for Cultural Heritage conservation

Nanoscale Horiz., 2024, 9,2069-2069
DOI: 10.1039/D4NH90062F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Rosangela Mastrangelo, David Chelazzi, Piero Baglioni
The content of this RSS Feed (c) The Royal Society of Chemistry




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Polymer-confined synthesis of gram-scale high-entropy perovskite fluoride nanocubes for improved electrocatalytic reduction of nitrate to ammonia

Nanoscale Horiz., 2024, Advance Article
DOI: 10.1039/D4NH00341A, Communication
Open Access
Guohao Xue, Tianlu Wang, Hele Guo, Nan Zhang, Claire J. Carmalt, Johan Hofkens, Feili Lai, Tianxi Liu
A high-entropy perovskite fluoride with a well-defined nanocubic structure was successfully prepared via a polyvinylpyrrolidone-confined nucleation strategy, demonstrating excellent electrocatalytic activity for nitrate reduction.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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De-escalation will follow restoring trust with China at LAC, says Army Chief

A day after India’s announcement, Beijing says a resolution has been reached over “relevant matters” on China-India border




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WHO to begin large-scale testing of Ebola vaccine




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MIT researchers make stamp-size stickers that can scan the human body

MIT professor Xuanhe Zhao said the development could open a new era of wearable imaging.




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Discussion and de-escalation in social media

It is a familiar situation: a compelling discussion develops on Tw­­itter, Facebook or Instagram - it could be about any topic - but instead of working constructively towards a common solution, the tone becomes increasingly aggressive. The rift between the differing opinions grows ever larger. Often, intercultural differences and lack of understanding are the root causes of the conflict. An international research team led by the University of Göttingen now wants to develop a "moderator" using artificial intelligence (AI) that can recognise hate messages in social media and intervene to de-escalate the situation. The Volkswagen Foundation will fund the project for four years from April 2021 with a total of around 1.5 million euros.

There has been a growing change in the style of communication in social media in recent years. This is particularly noticeable when it comes to questions of cultural identity. There is increasing conflict: users become emotional and attack each other; always anxious to emphasise what divides rather than what they have in common. A constructive exchange of information, facts and arguments takes place to a very limited extent. This leads to the well-known phenomena of filter bubbles and echo chambers in social media.




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One-pot spatial engineering of multi-enzymes in metal–organic frameworks for enhanced cascade activity

J. Mater. Chem. A, 2024, 12,30318-30328
DOI: 10.1039/D4TA06211F, Paper
Wenqing Fan, Kang Liang, Jieying Liang
A one-pot strategy was developed for the first time to achieve the precise spatial arrangement of multiple enzymes in MOFs, improving multi-enzyme cascade efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Development and application of Few-shot learning methods in materials science under data scarcity

J. Mater. Chem. A, 2024, 12,30249-30268
DOI: 10.1039/D4TA06452F, Review Article
Yongxing Chen, Peng Long, Bin Liu, Yi Wang, Junlong Wang, Tian Ma, Huilin Wei, Yue Kang, Haining Ji
Machine learning, as a significant branch of artificial intelligence, shortens the cycle of material discovery and synthesis by exploring the characteristics of data.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Scalable Synthesis of N–Doped Graphene–Oxide–Supported FeCo(OH)x Nanosheets for Efficient Co–Doped Fe3O4 Nanoparticle-Based Oxygen Reduction Reaction Electrocatalysis

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA06684G, Paper
Open Access
Sunglun Kwon, Jong Hyeon Lee
Developing efficient and cost-effective materials is crucial for advancing electrochemical oxygen reduction reaction (ORR). This study presents a synthesis route for high-performance spinel Fe and Co oxide nanoparticles on N-doped...
The content of this RSS Feed (c) The Royal Society of Chemistry




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How Reliable Is Scanguard?

Despite their claims penalized able to identify threats different antivirus application can’t, Scanguard is far away from reliable. The antivirus engine is time-consuming, the program triggers a lot of false advantages (it by accident blocks secure files seeing that malware), and it doesn’t always effectively identify all kinds of malware. This is why this failed […]




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'Laapataa Ladies' picked as India's entry for Oscars 2025

The Hindi film, a light-hearted satire on patriarchy, was chosen from a list of 29 films, including Bollywood hit "Animal", Malayalam National Award winner "Aattam" and Cannes winner "All We Imagine As Light"




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From ‘Downton Abbey’ to Oscar glory: Maggie Smith’s remarkable journey ends

Smith’s remarkable career spanned several decades, during which she was celebrated as one of her generation’s most distinguished actresses, sharing the stage and screen with contemporaries like Vanessa Redgrave and Judi Dench.




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Hindi cinema dominates India’s Oscar submissions

Selected from a pool of around 29 Indian language films, Lapata Ladies will represent India on the global stage. 




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Scan, pay, repeat: Behavioural shift on payment modes drives UPI transactions of over ₹617 trillion in past 102 months

Even small amounts of ₹1 are transacted on the ‘Made-In-India’ UPI platform




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Digital vigilante takes on scams in app stores of tech giants 

“I started because I was curious enough and this issue was not being fixed by the app stores,” says Babu Lal




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And the Oscar goes to...

Paul Giamatti deserves a Best Actor Oscar for his performance in The Holdovers



  • From the Viewsroom

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Indian telecom industry landscape

The industry is poised to benefit from several favourable factors




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Landscape of gold industry in India

The middle class continues to be the primary consumer of gold in India




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Scare at Kaddam project as it gets higher flood than discharge

People in 12 villages downstream vacated, shifted to relief camps. Spillway discharge of flood waters begins at Jurala as Almatti, Narayanpur let out water




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Katra Marriott Resort & Spa: A luxurious escape near Vaishno Devi shrine

Marriott hotel’s 150th location in India comes with bunk beds in family rooms, a 24×7 wellness centre, a fully equipped spa and scrumptious local delights.




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Police warn residents of cyber scams




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One-pot and large-scale production of uniform ytterbium-doped perovskite nanocrystals with controllable optical properties

J. Mater. Chem. C, 2024, 12,17647-17657
DOI: 10.1039/D4TC03364G, Paper
Jing Chu, Linxuan Zhang, Quanjie Lv, Yijun Han, Kang Sun, Ke Tao
Monodispersed Yb3+:CsPbCl3 nanocrystals with tunable optical properties were synthesized via a scalable one-pot method. The mechanism of size evolution based on digestive ripening was proposed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rain, the response to water scarcity



  • Solutions & Co

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Why KBC Still SCARES Amitabh Bachchan

Amitabh Bachchan, surprisingly, feels a sense 'dar' as to how he will conduct himself on KBC.




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'I was scared to hit Shah Rukh'

'I thought I was the action hero, but Shah Rukh is the number one action hero of the country today.'




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Health cover: Too little, too scarce

80% not covered by any insurance, dependent on private sector for treatment.



  • Policy & Issues

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Be wary of realty scams

Exercise maximum caution to prevent fraudulent transactions, says G. Shyam Sunder




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Two arrested for alleged job scam in Salem




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Escalator installed at Salem two-tier bus stand yet to open to the public