जीप इंडिया ने हाल ही में अपनी कोई भी कार भारतीय बाजार में नहीं उतारी है, लेकिन इसका मतलब यह नहीं है कि कंपनी अपनी नई कार पर काम नहीं कर रही है। आपको बता दें कि जीप इंडिया भारत में

The news of Irrfan Khan's shocking demise is yet to sink in. The actor died of neuroendocrine tumour on April 29, 2020. One of his films Piku, co-starring Amitabh Bachchan and Deepika Padukone, completes 5 years today (May 8, 2020).

Irrfan Khan lost his battle against neuroendocrine tumour, and left for his heavenly abode on April 29, 2020. However, it's hard to believe that the actor is no longer with us. Besides Irrfan's family and friends, even his co-stars continue to

Fans and cine-goers have been eagerly awaiting the release of Kiccha Sudeep’s highly anticipated next, Kotigobba 3. The Sandalwood biggie was initially scheduled to release on April 30. However, due to the COVID-19 pandemic and nationwide lockdown, the release of the

The nation woke up to the sad news of legendary Bollywood star Rishi Kapoor's demise today on April 30. The 67-year-old actor, who was suffering from cancer, was shooting for a film in Delhi when he fell ill again earlier this

Yash and Radhika Pandit recently shared the first picture of their 6-month-old son with fans on social media. For the unversed, the Sandalwood star couple became proud parents to a baby boy last year in October. And now, in an interview with TOI, Yash

Jeep launched the Compass SUV back in 2017 in the Indian market. Since its inception, the SUV has been a popular name in its segment as it comes loaded with several standard safety features. The Compass is available in a five-seater

With the COVID-19 virus causing a pandemic of an unprecedented level across the world, most countries including India have ordered a complete nationwide lockdown. This involves everyone staying at home, socially distancing themselves from everyone else. The central government of India

COVID-19 lockdown has affected the day-to-day activities of people worldwide. There's a change in the work-life system, daily routines, meal timings and the most important, sleep pattern. According to a survey carried out by Wakefit, a company based on innovative sleep

China's central bank said on Sunday it will make prudent monetary policy more flexible and step up counter-cyclical adjustments to support the real economy and fend off financial risks.

'They should know that we are still protesting as Delhi votes and will continue the agitation after the polling'

A wall is being constructed in front of a slum along the road connecting Sardar Vallabhbhai Patel International Airport to Indira Bridge.

Jagan stresses screening of all suspect cases

Goa police has decided to conduct random checks at government offices, shops and public places and act against those who do not wear masks and follow social distancing norms.

A three-year-old boy, who was sleeping next to his mother in their house near Magadi, was dragged out and killed by a leopard on Friday midnight. The child’s family had kept the door open as it was too hot when the leopard sneaked in

Case against shopkeeper for selling hookah

Leopard drags, kills boy sleeping next to mother

A cop performed the final rites of a stranger who died of a cardiac stroke. The family members of Pramod Khare (42), a bachelor, are settled in Delhi, Kolkata, Dubai and South Africa could not make it due to the lockdown. The funeral was live-streamed for them.

In transmission X-ray microscopy (TXM) systems, the rotation of a scanned sample might be restricted to a limited angular range to avoid collision with other system parts or high attenuation at certain tilting angles. Image reconstruction from such limited angle data suffers from artifacts because of missing data. In this work, deep learning is applied to limited angle reconstruction in TXMs for the first time. With the challenge to obtain sufficient real data for training, training a deep neural network from synthetic data is investigated. In particular, U-Net, the state-of-the-art neural network in biomedical imaging, is trained from synthetic ellipsoid data and multi-category data to reduce artifacts in filtered back-projection (FBP) reconstruction images. The proposed method is evaluated on synthetic data and real scanned chlorella data in 100° limited angle tomography. For synthetic test data, U-Net significantly reduces the root-mean-square error (RMSE) from 2.55 × 10−3 µm−1 in the FBP reconstruction to 1.21 × 10−3 µm−1 in the U-Net reconstruction and also improves the structural similarity (SSIM) index from 0.625 to 0.920. With penalized weighted least-square denoising of measured projections, the RMSE and SSIM are further improved to 1.16 × 10−3 µm−1 and 0.932, respectively. For real test data, the proposed method remarkably improves the 3D visualization of the subcellular structures in the chlorella cell, which indicates its important value for nanoscale imaging in biology, nanoscience and materials science.

Earth's North Magnetic Pole Keeps Drifting towards Siberia, Latest World Magnetic Model Shows | Geophysics, Geoscience  Sci-News.com

In this article, a method is presented to estimate a new local quality measure for 3D cryoEM maps that adopts the form of a `local resolution' type of information. The algorithm (DeepRes) is based on deep-learning 3D feature detection. DeepRes is fully automatic and parameter-free, and avoids the issues of most current methods, such as their insensitivity to enhancements owing to B-factor sharpening (unless the 3D mask is changed), among others, which is an issue that has been virtually neglected in the cryoEM field until now. In this way, DeepRes can be applied to any map, detecting subtle changes in local quality after applying enhancement processes such as isotropic filters or substantially more complex procedures, such as model-based local sharpening, non-model-based methods or denoising, that may be very difficult to follow using current methods. It performs as a human observer expects. The comparison with traditional local resolution indicators is also addressed.

Mitochondrial calcium uptake proteins 1 and 2 (MICU1 and MICU2) mediate mitochondrial Ca2+ influx via the mitochondrial calcium uniporter (MCU). Its molecular action for Ca2+ uptake is tightly controlled by the MICU1–MICU2 heterodimer, which comprises Ca2+ sensing proteins which act as gatekeepers at low [Ca2+] or facilitators at high [Ca2+]. However, the mechanism underlying the regulation of the Ca2+ gatekeeping threshold for mitochondrial Ca2+ uptake through the MCU by the MICU1–MICU2 heterodimer remains unclear. In this study, we determined the crystal structure of the apo form of the human MICU1–MICU2 heterodimer that functions as the MCU gatekeeper. MICU1 and MICU2 assemble in the face-to-face heterodimer with salt bridges and me­thio­nine knobs stabilizing the heterodimer in an apo state. Structural analysis suggests how the heterodimer sets a higher Ca2+ threshold than the MICU1 homodimer. The structure of the heterodimer in the apo state provides a framework for understanding the gatekeeping role of the MICU1–MICU2 heterodimer.

The most puzzling characteristic of deep-sea dragonfishes (stromiids) is found where their backbone (or vertebral column) approaches the back of their skull. In the anterior region of the backbone, these […]

The post Deep-sea dragonfish research appeared first on Smithsonian Insider.

The National Zoo has received a breeding pair of Asian small-clawed otters at Asia Trail for the first time. Mac, a three-year-old male from the Point Defiance Zoo in Tacoma, Wash., and Smidge, a five-year-old female from the Columbus Zoo in Ohio, arrived in April and are now in their exhibit.

The post Keepers are optimistic about Zoo’s new breeding pair of Asian small-clawed otters appeared first on Smithsonian Insider.

Any adventurer, hiker or backyard naturalist with a camera can help scientists survey and hopefully save the world’s amphibians thanks to a new social networking site that links “citizen scientists” with researchers tracking the decline of amphibians around the globe.

The post Scientists turn to social networking and citizen scientists to help keep track of amphibians appeared first on Smithsonian Insider.

Astronomers have probed into the distant universe and discovered that galaxies display one of two distinct behaviors: they are either awake or asleep, actively forming stars or are not forming any new stars at all.

The post Astronomers find that galaxies are either asleep or awake appeared first on Smithsonian Insider.

The nature of dark matter is a mystery -- a mystery that a new study has only deepened.

The post Dark matter mystery deepens appeared first on Smithsonian Insider.

Smithsonian scientists and collaborators have determined the evolutionary family tree for one of the most strikingly diverse and endangered bird families in the world, the Hawaiian honeycreepers.

The post Complete evolutionary tree of the Hawaiian honeycreepers traced by Smithsonian scientists, collaborators appeared first on Smithsonian Insider.

DNA analysis has established that creatures captured during a voyage to the mid-Atlantic are members of the Torquaratoridae; a recently discovered family of acorn worms.

The post Strange deep sea creatures confirmed as three new species appeared first on Smithsonian Insider.

This image shows one of three newly discovered North Atlantic deep sea acorn worms–Purple species–recently captured by scientists from deep in the mid-Atlantic Ocean. These […]

The post North Atlantic deep sea acorn worm – Purple species appeared first on Smithsonian Insider.

Scientists conducting deep-sea research in the Galapagos have described a new species of catshark. The new shark is approximately a foot long and has a chocolate-brown coloration with pale, irregularly distributed spots on its body. The spotted patterns appear to be unique to each individual.

The post New species of deep-sea catshark described from the Galapagos appeared first on Smithsonian Insider.

Clearly visible connecting the dark-purple cephalopods was the white “terminal organ” or penis of the male, extending out through the male’s funnel.

The post First detailed sex video of deep-sea squid resolves long-standing mysteries as to how these animals mate appeared first on Smithsonian Insider.

According to legend St. Patrick (circa 387–460 or 492 AD) banished all snakes from Ireland, chasing them into the sea after they attacked him during […]

The post Note to St. Patrick: Pls. keep the snakes appeared first on Smithsonian Insider.

In 2009, during an expedition by a Russian research ship, a small length of yellow flesh about 5 centimeters long was dredged up from the […]

The post Last seen 140 years ago, deep sea worm resurfaces, delighting scientists appeared first on Smithsonian Insider.

Mention coral reefs and images like snorkeling, tropical fish and sunny island getaways pop to mind. Vacation packages are not being offered, however, for many […]

The post Cold, dark and lonely: Deep-water corals thrive where the sun never shines appeared first on Smithsonian Insider.

What crunchy food did Americans spend $5.5 billion on last year—with sales that spiked before snow and ice storms? If you guessed birdseed then you […]

The post Simple tips to keep your backyard birds healthy this winter appeared first on Smithsonian Insider.

You watch the weather forecast, gear up with hat, coat, scarf and gloves, but you still get cold after just a short time in the […]

The post Keeping Warm in Winter is for the Birds appeared first on Smithsonian Insider.

Like other kids at summer camp, a group of youngsters in the cities of Miami, Okla. and Fort Wayne, Ind. play games, work on crafts […]

The post Digitized, Searchable Archives Help Revive ‘Sleeping’ Languages appeared first on Smithsonian Insider.

Surplus mustard gas canisters and unexploded bombs dumped in the Pacific Ocean near Hawaii after WWII, have become, scientists say, a potential reef that is […]

The post Old bombs, chemical weapons now home for deep-sea starfish appeared first on Smithsonian Insider.

Recently crowned the “astronomy photo of the year” by Slate’s Bad Astronomy blog, a new image of a region of Orion’s belt reveals the deepest […]

The post Stunning deep space photo reveals new details of Orion nebulae appeared first on Smithsonian Insider.

Bei Bei, Bao Bao, Tian Tian. Many people recognize the names of the giant pandas that reside at the Smithsonian’s National Zoo. Yet Juan Rodriguez […]

The post Meet Juan Rodriguez, panda keeper at the National Zoo appeared first on Smithsonian Insider.