mar

BCCL To Host Open House On March 14

The Bermuda Centre for Creative Learning [BCCL] will be hosting an open house on Saturday, March 14 from 9.00am to 11.00am. A spokesperson said, “BCCL is a private school for students who have a language-based learning difference, beginning at age six. Prospective parents are welcome to attend and learn more about BCCL’s personalized learning approach. […]

(Click to read the full article)




mar

Minister Rabain On Math In Primary Schools

Minister of Education Diallo Rabain spoke in the House of Assembly today [March 11] about the Mathematics Intervention Programme that has been implemented in the island’s public primary schools. Minister Rabain said, “In February 2018, I shared the Cambridge Checkpoint and IGCSE results for the 2017/2018 school year. During that press conference, I advised the […]

(Click to read the full article)




mar

The ‘Second Last Supper’ Set For Late March

With an all star cast of over 30 members, a live band, a dramatic opening and more, Dale Butler [pictured left] is set to release his third play, directed by Rotimi Martins, entitled ‘The Second Last Supper.’ The play will be staged on March 26, 27, and 28 at St. Paul A.M.E. Centennial Hall. In […]

(Click to read the full article)




mar

Coldwell Banker Mid-Summer Market Update

Coldwell Banker Bermuda Realty provided their 2019 Mid-Summer Market update, saying that “in-house analysis indicates between January and April of this year, 111 properties had price reductions island wide” and there has been an increase in the  number of cash buyers. A spokesperson said, “‘What’s the market like?’ The summer provides us with numerous opportunities to […]

(Click to read the full article)




mar

Column: Why I Never Use Airbnb’s Smart Pricing

[Column written by Ade Brown] One of the most common questions I get asked is whether or not to use Airbnb’s pricing tips. Don’t! This is a very common mistake that new hosts make, even myself. I fell victim to Airbnb’s pricing band. While using smart pricing was great in getting my calendar filled, it […]

(Click to read the full article)




mar

Coldwell Banker Real Estate Market Update

Coldwell Banker Bermuda Realty has released their annual update, saying that “the year 2019 was challenging to navigate.” A spokesperson said, “The year 2019 was challenging to navigate and certainly difficult to make predictions even after compiling and interpreting our quarterly sales transactional data. “Although the early part of 2019 suggested that market performance was […]

(Click to read the full article)




mar

Column: Market Vacation Rental On Social Media

[Column written by Ade Brown] Vacation rental owners should use social media to market their properties directly to a wide variety of potential guests. Social media can be used as a free advertising tool in reaching people all around the world. People can come across your page simply by scrolling through their feed, and every […]

(Click to read the full article)




mar

Court: Man Denies Murder Of Marcus Gibbings

[Written by Don Burgess] Cleveland Rogers denied a murder charge in Supreme Court today [Nov 1]. The defendant pleaded not guilty of the premeditated murder of Marcus Gibbings on or about October 25, 2006. Mr Gibbings, who was from Trinidad, was found stabbed to death in an apartment in Devonshire. His next court appearance is set […]

(Click to read the full article)




mar

Police Warn About Fake MarketPlace Website

The Bermuda Police Service [BPS] is warning the public about a fake website claiming to represent The MarketPlace that is “deceiving residents with an alleged $250 gift card giveaway.” A police spokesperson said, “The Bermuda Police Service is aware of a fake website claiming to represent The MarketPlace that is deceiving residents with an alleged […]

(Click to read the full article)




mar

Attempted Robbery At ScooterMart In Paget

Two men entered ScooterMart in Paget and attempted to rob the store, however they “were unsuccessful in their attempt and left riding a motorcycle west along Lover’s Lane.” A police spokesperson said, “At around 11:30am on 9th March 2020, police responded to a report of two men dressed in dark clothing, who entered the ScooterMart […]

(Click to read the full article)




mar

March 31: Deadline For BTA Tourism Programme

The Bermuda Tourism Authority [BTA] reminds local entrepreneurs that the deadline for applications to its Experience Investment Programme is on Tuesday, March 31st. A spokesperson said, “Despite Covid-19 uncertainty, the Bermuda Tourism Authority [BTA] is reminding local entrepreneurs the deadline for applications to its Experience Investment Programme closes a week today, Tuesday, March 31. “The […]

(Click to read the full article)




mar

88 Visit KEMH Due To Road Accidents In March

88 people visited the Hospital’s Emergency Department or Urgent Care Centre last month due to road traffic accidents, according to the latest statistics from the Bermuda Hospitals Board [BHB]. According to the BHB, “Bermuda Hospitals Board road traffic accident statistics for the period 1 January – 31 March 2020 show the following: “88 cases were […]

(Click to read the full article)




mar

Marine Board call for nominations by June 15

The Marine Board of the National Academies of Sciences, Engineering, and Medicine (National Academies) is seeking nominations for new members to be appointed to three-year terms that would commence on November 1, 2020. There will be five (5) vacancies on the Board in 2020 and there is particular interest in candidates with expertise in the following areas: Naval Architecture and Naval Engineering Shipbuilding/Shipyard Operations Vessel Pilotage and Harbor Operations Seaport Administration, Planning, and ...




mar

TR News 326: March-April 2020 table of contents now online

The March-April 2020 issue of TR News (#326) - including a cover feature on TRB's "century of progress and foundation for the future" of transportation research - is available in hard copy and digital copy for subscribers. For those who are not subscribers, the table of contents is available. Other feature articles in the issue include ones on whether research processes can keep up, accessible rail sleeper compartments, drones and lasers for railroad bridges, implications of California wildfires, and muc...




mar

Estimating Market Value and Establishing Market Rent at Small Airports

Staff from smaller airports typically lack specialized expertise in the negotiation and development of airport property or the resources to hire consultants. The TRB Airport Cooperative Research Program's ACRP Research Report 213: Estimating Market Value and Establishing Market Rent at Small Airports provides airport management, policymakers, and staff a resource for developing and leasing airport land and improvements, methodologies for determining market value and appropriate rents, and best practices ...



  • http://www.trb.org/Resource.ashx?sn=cover_acrp_rpt_213

mar

Our Review of Stellina: a ‘Smart Telescope’ for 21st Century Astronomy

A new breed of smart telescopes is set to take users past these hurdles, and get them out under the night sky. We recently had a chance to put Vaonis’ Stellina ‘smart telescope’ through its paces, and we’re intrigued at the glimpse it provides at the future of observational astronomy.

The post Our Review of Stellina: a ‘Smart Telescope’ for 21st Century Astronomy appeared first on Universe Today.





mar

Review: Galileo and the Science Deniers by Mario Livio

So, you think you know Galileo? A new book out from Simon and Schuster publishing looks at the life and times of one of the most famous astronomers there ever was: Galileo Galilei. Galileo and the Science Deniers by Dr. Mario Livio not only looks at the life and times of the famous astronomer Galileo, but busts some of the most famous myths surrounding Galileo, and looks at his greatest discoveries and tempestuous clash with the Roman Catholic Church and its aftermath. Livio also connects the science denialism of the day, with comparisons to modern clashes between politics and science.

The post Review: Galileo and the Science Deniers by Mario Livio appeared first on Universe Today.




mar

TR News 326: March-April 2020 table of contents now online

The March-April 2020 issue of TR News (#326) - including a cover feature on TRB's "century of progress and foundation for the future" of transportation research - is available in hard copy and digital copy for subscribers. For those who are not subscribers, the table of contents is available. Other feature articles in the issue include ones on whether research processes can keep up, accessible rail sleeper compartments, drones and lasers for railroad bridges, implications of California wildfires, and muc...




mar

Mesajul Primarului Municipiului Timișoara, dl. Ncolae Robu, cu ocazia Zilei Europei

Stimați și dragi timișoreni



  • Comunicate de presa

mar

infffirmary




mar

Mark of the Funpire




mar

In summary




mar

Drug Lord's Hippos Make Their Mark on Foreign Ecosystem

Scientists published the first assessment of the impact that invasive hippos imported by drug lord Pablo Escobar are having on Colombian aquatic ecosystems. The hippos are changing the area's water quality by importing large amounts of nutrients and organic material from the surrounding landscape.




mar

Marivi Fernandez-Serra: Then and Now

Marivi Fernandez-Serra is a professor in the Department of Physics and Astronomy at Stony Brook University.




mar

Fans Port Mario 64 To PC And Make It Way Better, So Of Course Nintendo Is Trying To Nuke The Project

I'm lucky enough to own a decades old Nintendo 64 and a handful of games, including the classic Mario 64. My kids love that game. Still, the first thing they asked when I showed it to them the first time is why the screen was letterboxed, why the characters looked like they were made of lego blocks, and why I needed weird cords to plug it all into the flat screen television. The answer to these spoiled monsters' questions, of course, is that the game is super old and wasn't meant to be played on modern televisions. It's the story of a lot of older games, though many PC games at least have a healthy modding community that will take classics and get them working on present day hardware. Consoles don't have that luxury.

Well, usually, that is. It turns out that enough folks were interested in modernizing Mario 64 that a group of fans managed to pull off porting it to PC. And, because this is a port and not emulation, they managed to update it to run in 4k graphics and added a ton of modern visual effects.

Last year, Super Mario 64's N64 code was reverse-engineered by fans, allowing for all kinds of new and exciting things to be done with Nintendo’s 1996 classic. Like building a completely new PC port of the game, which can run in 4K and ultra-wide resolutions.

This is a very new and cool thing! Previously, if you were playing Super Mario 64 on PC, you were playing via emulation, as your PC ran code pretending to be an N64. This game is made specifically for the PC, built from the ground up, meaning it not only runs like a dream, but even supports mod stuff like ReShade, allowing for graphical tweaks (like the distance blur seen here).

As you'll see, the video the Kotaku post is referencing can't be embedded here because Nintendo already took it down. Instead, I'll use another video that hasn't been taken down at the time of this writing, so you can see just how great this looks.

In addition to videos of the project, Nintendo has also been busy firing off legal salvos to get download links for the PC port of the game taken down from wherever it can find them. Now, while Nintendo's reputation for IP protectionism is such that it would almost certainly take this fan project down under virtually any circumstances, it is also worth noting that the company has a planned re-release of Mario 64 for its latest Nintendo console. That likely only supercharged the speed with which it is trying to disappear this labor of love from fans of an antiquated game that have since moved on to gaming on their PCs.

But why should the company do this? Nintendo consoles are known for many things, including user-friendly gaming and colorful games geared generally towards younger audiences. You know, exactly not the people who would take it on themselves to get an old Mario game working on their PC instead of a Nintendo console. What threat does this PC port from fans represent to Nintendo revenue? It's hard to imagine that threat is anything substantial.

And, yet, here we are anyway. Nintendo, after all, doesn't seem to be able to help itself.




mar

No, Congress Can't Fix The Broken US Broadband Market In A Mad Dash During A Pandemic

COVID-19 has shone a very bright light on the importance of widely available, affordable broadband. Nearly 42 million Americans lack access to any broadband whatsoever--double FCC estimates. And millions more can't afford service thanks to a lack of competition among very powerful, government pampered telecom monopolies.

As usual, with political pressure mounting to "do something," DC's solution is going to be to throw more money at the problem:

"The plan unveiled Thursday would inject $80 billion over five years into expansion of broadband infrastructure into neglected rural, suburban and urban areas, with an emphasis on communities with high levels of poverty. It includes measures to promote rapid building of internet systems, such as low-interest financing for infrastructure projects."

To be clear, subsidies often do help shore up broadband availability at coverage. The problem is that the United States government, largely captured by telecom giants with a vested interest in protecting regional monopolies, utterly sucks at it.

Despite ample pretense to the contrary, nobody in the US government actually knows where broadband is currently available. Data supplied by ISPs has never been rigorously fact-checked by a government fearful of upsetting deep-pocketed campaign contributors (and valued NSA partners). As a result, our very expensive ($350 million at last count) FCC broadband coverage map creates a picture of availability and speed that's complete fantasy. It's theater designed to disguise the fact that US broadband is mediocre on every broadband metric that matters. Especially cost.

While there has been some effort to fix the mapping problem via recent legislation, the FCC still needs several years (and more money) to do so. And while you'd think this would be more obvious, you can't fix a problem you can't even effectively measure. There's also not much indication that the $80 billion, while potentially well intentioned, would actually get where it needs to go. Especially right now, when federal oversight is effectively nonexistent.

You may or may not have noticed this, but US telecom is a corrupt, monopolized mess. Giants like AT&T and Comcast all but own state and federal legislatures and, in many instances, literally write the law. Feckless regulators bend over backward to avoid upsetting deep-pocketed campaign contributors. So when subsidies are doled out, they very often don't end up where regulators and lawmakers intended. There's an endless ocean of examples where these giants took billions in taxpayer subsidies to deploy fiber networks that are never fully delivered.

If you were to do meaningful audit (which we've never done because again we're not willing to adequately track the problem or stand up to dominant incumbent corporations) you'd very likely find that American taxpayers already paid for fiber to every home several times over.

That's not to say is that there aren't things Congress could do to help the disconnected during COVID-19. Libraries for example have been begging the FCC for the ability to offer expanded WiFi hotspot access (via mobile school buses) to disconnected communities without running afoul of FCC ERate rules. But while the FCC said libraries can leave existing WiFi on without penalty, it has been mute about whether they can extend coverage outside of library property. Why? As a captured agency, the FCC doesn't like anything that could potentially result in Comcast or AT&T making less money.

None of this is to say that we shouldn't subsidize broadband deployment once we get a handle on the mapping problem. But it's a fantasy to think we're going to immediately fix a 30 year old problem with an additional $80 billion in a mad dash during a pandemic. US broadband dysfunction was built up over decades. It's the product of corruption and rot that COVID-19 is exposing at every level of the US government. The only way to fix it is to stand up to industry, initiate meaningful reform, adopt policies that drive competition to market, and jettison feckless lawmakers and regulators whose dominant motivation is in protecting AT&T, Verizon, Comcast, and Spectrum revenues.

Maybe the pandemic finally provides the incentive to actually do that, but until the US does, these subsidization efforts are largely theater.




mar

COVID-19 Is Exposing A Virulent Strain Of Broadband Market Failure Denialism

A few weeks ago, the US telecom industry began pushing a bullshit narrative through its usual allies. In short, the claim revolves around the argument that the only reason the US internet still works during a pandemic was because the Trump FCC ignored the public, ignored most objective experts, and gutted itself at the behest of telecom industry lobbyists. The argument first popped up over at AEI, then the Trump FCC, then the pages of the Wall Street Journal, and has since been seen in numerous op-eds nationwide. I'd wager that's not a coincidence, and I'd also wager we'll be seeing a lot more of them.

All of the pieces try to argue that the only reason the US internet works during a pandemic is because the FCC gutted its authority over telecom as part of its "restoring internet freedom" net neutrality repeal. This repeal, the story goes, drove significant investment in US broadband networks (not remotely true), resulting in telecom Utopia (also not true). The argument also posits that in Europe, where regulators have generally taken a more active role in policing things like industry consolidation and telecom monopolies, the internet all but fell apart (guess what: not true).

Usually, like in this op-ed, there's ample insistence that the US broadband sector is largely wonderful while the EU has gone to hell:

"Unlike here, European networks are more heavily regulated. This has led to less investment and worse performance for consumers for years. American consumers are being generally well served by the private sector."

Anybody who has spent five minutes talking to Comcast customer support -- or tried to get scandal-plagued ISP like Frontier Communications to upgrade rotten DSL lines -- knows this is bullshit. Still, we penned a lengthy post exploring just how full of shit this argument is, and how there's absolutely zero supporting evidence for the claims. The entire house of cards is built on fluff and nonsense, and it's just ethically grotesque to use a disaster to help justify regulatory capture and market failure.

While it's true that the US internet, in general, has held up relatively well during a pandemic, the same can't be said of the so called "last mile," or the link from your ISP's network to your home. Yes, the core internet and most primary transit routes, designed to handle massive capacity spikes during events like the Superbowl, has handled the load relatively well. The problem, as Sascha Meinrath correctly notes here, is sluggish speeds on consumer and business lines that, for many, haven't been upgraded in years:

"Right now, an international consortium of network scientists is collecting 750,000 U.S. broadband speed tests from internet service provider (ISP) customers each day, and we’ve been tracking a stunning loss of connectivity speeds to people’s homes. According to most ISPs, the core network is handling the extra load. But our data show that the last-mile network infrastructure appears to be falling down on the job."

Again, your 5 Mbps DSL line might be ok during normal times, but it's not going to serve you well during a pandemic when your entire family is streaming 4K videos, gaming, and Zooming. And your DSL line isn't upgraded because there's (1) very little competition forcing your ISP to do so, and (2) the US government is filled to the brim with sycophants who prioritize campaign contributions and ISP revenues over the health of the market and consumer welfare. And while there's a contingency of industry-linked folks who try very hard to pretend otherwise, this is a policy failure that's directly tied to mindless deregulation, a lack of competition, and, more importantly, corruption. In short, the complete opposite of the industry's latest talking point.

For years we've been noting how US telcos have refused to repair or upgrade aging DSL lines because it's not profitable enough, quickly enough for Wall Street's liking. Facing no competition and no regulatory oversight, there's zero incentive for a giant US broadband provider to try very hard. Similarly, because our lawmakers and regulators are largely of the captured, revolving door variety, they rubber stamp shitty mergers, turn a blind eye to very obvious industry problems, routinely throwing billions in taxpayer money at monopolies in exchange for fiber networks that are usually only partially deployed -- if they're deployed at all.

Meanwhile, US telcos that have all but given up on upgrading aging DSL lines have helped cement an even bigger Comcast monopoly across vast swaths of America. It's a problem that the telecom sector, Trump FCC, and various industry apologists will ignore to almost comical effect. Also ignored is the fact that this results in US broadband subscribers paying some of the highest prices for broadband in the developed world:

"Numerous studies, including those conducted by the FCC itself, show that broadband pricing is the second-largest barrier to broadband adoption (availability is the first). It’s obvious that if people are being charged a lot for a service, they’re less likely to purchase it. And independent researchers have already documented that poor areas often pay more than rich communities for connectivity. Redlining of minority and rural areas appears to be widespread, and we need accurate pricing data from the FCC to meaningfully address these disparities."

Try to find any instance where Ajit Pai, or anybody in this chorus of telecom monopoly apologists, actually admits that the US broadband market isn't competitive and, as a result, is hugely expensive for businesses and consumers alike. You simply won't find it. What you will find are a lot of excuses and straw men arguments like this latest one, designed to distract the press, public, and policymakers from very obvious market failure. Market failure that was a major problem in normal times, and exponentially more so during a pandemic where broadband is an essential lifeline.




mar

FYI: Your browser can pick up ultrasonic signals you can't hear, and that sounds like a privacy nightmare to some

High-frequency audio could be used to stealthily track netizens

Technical folks looking to improve web privacy haven't been able to decide whether sound beyond the range of human hearing poses enough of a privacy risk to merit restriction.…




mar

Backup and restore on AWS is a nightmare – is there a way to speed it up?

Apparently. But we’re so incredulous, we’re gonna test those claims on live internet TV…

Webcast “The journey to cloud” echoes through all organisations. It’s a Bildungsroman – a story of empowerment and betterment. A shiny, towering cityscape of gleaming edifices and elegant spires. It’s like an ascension into the actual clouds. Like dying and waking up in heaven.…




mar

One malicious MMS is all it takes to pwn a Samsung smartphone: Bug squashed amid Android patch batch

Zero-click remote-code exec hole found by Googler, updates emitted

Samsung has patched a serious security hole in its smartphones that can be exploited by maliciously crafted text messages to hijack devices.…




mar

DXOMARK: фронтальная камера iPhone 11 хуже, чем у топовых Android-смартфонов

И хуже, чем фронталка iPhone 11 Pro Max.




mar

Huawei представила в Европе смартфон P Smart 2020: с сервисами Google и ценником €200

Благодаря чипу Kirin 710F смартфон получил предустановленные чипы Google.




mar

Recognizing energy efficient ceiling fans on the market

Power reliable ceiling followers are a wonderful method to make your home much more inviting, visually pleasing and also, as an added bonus offer, reduced your overall house power air conditioning bill if you currently have a home cooling system.… Continue Reading




mar

Life's a Biotech - Marketing Dictionary for Newbies

As more and more of my academic scientist friends become disillusioned with their prospects for a balanced life or financial freedom, moving to industry seems the logical choice. If you really want to make the big dollars, you'll want to move out of the lab and try out marketing or sales. Now, you won't be able to go directly to a marketing position from the lab without some marketing experience o; (read more)

Source: Suzy - Discipline: BioTech




mar

Life's a Biotech - The Marketing of Science

I am a scientist for profit. This means, as you are well aware, I have to work with marketing people to generate pretty pictures showing perfect results with any product that we sell. You know those flyers and brochures and ads in BioTechniques where a tiny picture of a gel or a qPCR assay with photoshop perfect curves or bands is plopped on the page next to some meaningless picture and supposed t; (read more)

Source: Suzy - Discipline: BioTech




mar

Featured - The Science of Marketing: How Products are Born Part III

Picking up our discussion on the new product development life cycle, we last talked about R&D and before that feasibility. The next department to work on the new product is marketing. The person who will announce to the world the arrival of this new kit is the Product Manager or Marketing Manager.(If you do not recognize some terms used here, please ask or check the Marketing Dictionary.)Today; (read more)

Source: Suzy - Discipline: BioTech




mar

Smart, Helpful, FUNNY Flow Chart for Kid Independence

This flow chart, created by University of Virginia Psychology Professors Jim Coan and Daniel Willingham, is just plain terrific. “Could a child do this alone?” asks the chart. Then let ’em! “Could a child do this with some instruction?” Then let ’em. Etc. etc. Check it out — print it out! — by clicking here. […]




mar

Elon Musk, Trips To Mars, And A Mars Colony

I've previously argued that going to Mars and trying to live there is a dumb idea for the foreseeable future. Notwithstanding assorted recent comments by Elon Musk this is still true. The best treatment of Musk's proposal for a big trip to Mars comes from The Martian science fiction author Andy Weir in his comments to Ars Technica. I think Weir went too easy the obviously ridiculous low cost estimates made by Musk and didn't address many of the problems with a Mars colony. But he makes excellent points. Read the article if you are interested. I like Weir's point that solar panels weigh too much to cart all the way to Mars. Better to take a nuclear reactor. I've...




mar

World of Art Magazine, Londres, R-U a accordé Asbjorn Lonvig, Danemark "World of Art Award 2006"

On accorde "The World of Art Award" (WAA) aux artistes, aux galeries et aux musées qui poursuivent les "meilleures pratiques" dans l'art et la culture. Cette concurrence cherche à attirer dies artistes, galeries, les musées qui redéfinissent des normes de l'excellence d'art. Ceux qui défie des trends et des tendances existantes dans l'art et la culture.




mar

Getting Married in Heaven

A young couple was on their way to get married when they were involved in a fatal car accident. It was really bad, like something from a Quentin Tarantino movie. At any rate, they soon found themselves standing in front of the pearly gates of heaven staring at St. Peter himself. Upset, but wanting to […]

The post Getting Married in Heaven appeared first on Funny & Jokes.





mar

Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

Facioscapulohumeral muscular dystrophy (FSHD) is caused by loss of repression of the DUX4 gene; however, the DUX4 protein is rare and difficult to detect in human muscle biopsies, and pathological mechanisms are obscure. FSHD is also a chronic disease that progresses slowly over decades. We used the sporadic, low-level, muscle-specific expression of DUX4 enabled by the iDUX4pA-HSA mouse to develop a chronic long-term muscle disease model. After 6 months of extremely low sporadic DUX4 expression, dystrophic muscle presented hallmarks of FSHD histopathology, including muscle degeneration, capillary loss, fibrosis, and atrophy. We investigated the transcriptional profile of whole muscle as well as endothelial cells and fibroadiopogenic progenitors (FAPs). Strikingly, differential gene expression profiles of both whole muscle and, to a lesser extent, FAPs, showed significant overlap with transcriptional profiles of MRI-guided human FSHD muscle biopsies. These results demonstrate a pathophysiological similarity between disease in muscles of iDUX4pA-HSA mice and humans with FSHD, solidifying the value of chronic rare DUX4 expression in mice for modeling pathological mechanisms in FSHD and highlighting the importance FAPs in this disease.




mar

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

Hypoxia-inducible factor (HIF) is strikingly upregulated in many types of cancer, and there is great interest in applying inhibitors of HIF as anticancer therapeutics. The most advanced of these are small molecules that target the HIF-2 isoform through binding the PAS-B domain of HIF-2α. These molecules are undergoing clinical trials with promising results in renal and other cancers where HIF-2 is considered to be driving growth. Nevertheless, a central question remains as to whether such inhibitors affect physiological responses to hypoxia at relevant doses. Here, we show that pharmacological HIF-2α inhibition with PT2385, at doses similar to those reported to inhibit tumor growth, rapidly impaired ventilatory responses to hypoxia, abrogating both ventilatory acclimatization and carotid body cell proliferative responses to sustained hypoxia. Mice carrying a HIF-2α PAS-B S305M mutation that disrupts PT2385 binding, but not dimerization with HIF-1β, did not respond to PT2385, indicating that these effects are on-target. Furthermore, the finding of a hypomorphic ventilatory phenotype in untreated HIF-2α S305M mutant mice suggests a function for the HIF-2α PAS-B domain beyond heterodimerization with HIF-1β. Although PT2385 was well tolerated, the findings indicate the need for caution in patients who are dependent on hypoxic ventilatory drive.





mar

iPhone 11 Pro Max уступил Xiaomi в тесте DxOMark

Эксперты из DxOMark протестировали камеры новых смартфонов iPhone 11 Pro и 11 Pro Max, и в результате испытаний новинки от компании Apple оказались недостаточно хороши, чтобы возглавить рейтинг. В общ...




mar

New NFC Specification Will Let Smartphones Charge Small Devices

A new NFC specification announced this week by the NFC Froum will allow future NFC enabled devices to offer wireless charging capabilities, which means a smartphone could be used to charge a small accessory like headphones.


According to the NFC Forum, the Wireless Charging Specification (WLC) will allow smartphones or other NFC charging devices to wirelessly charge small, battery-powered consumer and IoT devices at a power transfer rate of up to one watt.

The 1W rating is much slower than the Qi-based standard used by iPhones and other smartphones. Qi-based wireless charging on the iPhone maxes out at 7.5W, but is even faster on some Android devices.

Charging over NFC would require new hardware, and it's not a feature that can be added to existing devices. The NFC Forum believes the WLC specification could be used to complement Qi-based wireless charging.

It works using a single antenna to manage communications and charging, which is convenient for low-power devices like smart watches, fitness trackers, and earbuds that already use NFC for connectivity because there's no need to build in Qi support.

"The NFC Forum's Wireless Charging Technical Specification allows for wireless charging of small battery-powered devices like those found in many of the estimated 36 billion IoT devices in use today," said Koichi Tagawa, chair, NFC Forum. "NFC wireless charging is truly transformative because it changes the way we design and interact with small, battery-powered devices as the elimination of plugs and cords enables the creation of smaller, hermetically-sealed devices."
Apple in 2015 joined the NFC Forum and participates in the approval of new NFC specifications and developments.

Rumors in 2019 suggested that Apple was working on bilateral wireless charging that would allow its iPhones to charge the AirPods and the Apple Watch, but the feature was ultimately nixed. At the time, Apple analyst Ming-Chi Kuo said that the two-way wireless charging feature Apple was exploring did not meet Apple's requirements.

Samsung has implemented bilateral wireless charging in its smartphones, but the Wireless PowerShare option does not use NFC and is powered by the Qi-based charging coils in the device. Samsung's smartphones can charge other smartphones or accessories like headphones that support Qi wireless chargers.
Tag: NFC

This article, "New NFC Specification Will Let Smartphones Charge Small Devices" first appeared on MacRumors.com

Discuss this article in our forums





mar

Summary of Staff Discussion Draft: International Business Tax Reform

Senator Max Baucus, Chairman of the U.S. Senate Committee on Finance, releases a staff discussion draft on international business tax reform. Continue reading



  • Accountants CPA Hartford
  • Articles
  • Chairman Max Baucus U.S. Senate Committee on Finance
  • International Tax Reform
  • international tax system
  • November 19 2013
  • Proposals for tax reform
  • Senator Max Baucus
  • U.S. Senate Committee on Finance

mar

Bernie Sanders does not have to win the Iowa Primary to set up his race

Bernie Sanders does not have to win the Iowa primary; however, if the gets 35%, 40%, or 45% of the vote, that would set him up nicely for the New Hampshire primary, next door to his state of Vermont. Continue reading