The Dublin rock band had one of 2019's best albums - so what does the follow-up have in store?

The DML News App offers the best in news reporting.

The post REPORT: Prominent Task Force member, CDC director to quarantine after COVID-19 exposure appeared first on Dennis Michael Lynch.

The C-type lectin receptors (CLRs) form a family of pattern recognition receptors that recognize numerous pathogens, such as bacteria and fungi, and trigger innate immune responses. The extracellular carbohydrate-recognition domain (CRD) of CLRs forms a globular structure that can coordinate a Ca2+ ion, allowing receptor interactions with sugar-containing ligands. Although well-conserved, the CRD fold can also display differences that directly affect the specificity of the receptors for their ligands. Here, we report crystal structures at 1.8–2.3 Å resolutions of the CRD of murine dendritic cell-immunoactivating receptor (DCAR, or Clec4b1), the CLR that binds phosphoglycolipids such as acylated phosphatidyl-myo-inositol mannosides (AcPIMs) of mycobacteria. Using mutagenesis analysis, we identified critical residues, Ala136 and Gln198, on the surface surrounding the ligand-binding site of DCAR, as well as an atypical Ca2+-binding motif (Glu-Pro-Ser/EPS168–170). By chemically synthesizing a water-soluble ligand analog, inositol-monophosphate dimannose (IPM2), we confirmed the direct interaction of DCAR with the polar moiety of AcPIMs by biolayer interferometry and co-crystallization approaches. We also observed a hydrophobic groove extending from the ligand-binding site that is in a suitable position to interact with the lipid portion of whole AcPIMs. These results suggest that the hydroxyl group-binding ability and hydrophobic groove of DCAR mediate its specific binding to pathogen-derived phosphoglycolipids such as mycobacterial AcPIMs.

From playing the reruns of popular shows to using video conferencing tools to create content, broadcasters are using different methods to keep the audience entertained during lockdown

NDCP 2018 is made-to-order for resolution of the challenges seen today in the environment. However, this superb policy—almost entirely—is awaiting implementation since more than a year. 

Podcasts are looking like an increasingly viable channel to engage with customers

The CEO and cofounder defines adaptive messaging and shares the number one mistake marketers make when it comes to thinking about this concept. Plus, hear how Mary Poppins inspired his company's name

This Metasploit module exploits a stack overflow in the RPCSS service, this vulnerability was originally found by the Last Stage of Delirium research group and has bee widely exploited ever since. This Metasploit module can exploit the English versions of Windows NT 4.0 SP3-6a, Windows 2000, Windows XP, and Windows 2003 all in one request :)

Enel SpA is putting the final touches on a yieldco that would hold its U.S. renewable energy assets, making it the latest power-plant owner to opt for a structure that frees up capital.

Nigeria on Saturday recorded 239 new cases of COVID-19. The Nigeria Center for Disease Control, NCDC, confirmed this in a post on its Twitter page. This brings the total number of cases in Nigeria to 4151. Lagos recorded the highest number of cases with 97 new infected persons followed by Bauchi State which recorded 44 […]

NCDC confirms 239 new cases of COVID-19 as toll rises to 4151

In a case which may change how the Premier League chooses to structure broadcasting rights packages, on 4 October, the European Court of Justice (ECJ) ruled in favour of a pub landlady from Portsmouth, who was using a Greek decoder to screen Premier...

CDC chief ‘will be teleworking for the next two weeks’ after a 'low-risk exposure’

[Zimbabwe Standard] The Supreme Court's MDC-T presidential legitimacy has brought to the fore issues on appointments of key figures to Parliament; Zimbabwe Anti-Corruption Commission; and the MDC-T national executive.

GAINESVILLE, Florida: The decision to shelve detailed advice from the nation’s top disease control experts for reopening communities during the coronavirus pandemic came from the highest levels of the White House, according to internal government emails obtained, reported international...

GAINESVILLE, Florida: The decision to shelve detailed advice from the nation's top disease control experts for reopening communities during the coronavirus pandemic came from the highest levels of the White House, according to internal government emails obtained, reported international media.The...

GAINESVILLE, Florida: The decision to shelve detailed advice from the nation's top disease control experts for reopening communities during the coronavirus pandemic came from the highest levels of the White House, according to internal government emails obtained, reported international media. The...

The B.C. Centre of Disease Control says the Calgary to Kelowna flight happened on May 5.

New government estimate highlights stark differences between groups afflicted with HIV

Washington: Orders for vaccines against diseases such as measles have declined since a national emergency was declared in the United States because of the coronavirus pandemic, the US Centers for Disease Control and Prevention said Friday.The number of vaccine doses ordered around the country has...

Rawalpindi : Deputy Commissioner Captain Anwar ul Haq Saturday said that profiteering and hoarding would never be tolerated especially in the holy month of Ramazan and those found violating the law would be dealt strictly.In a statement issued here, he said that no one would be allowed to cheat...

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.

Here are the latest coronavirus updates from around the world.

The head of the Food and Drug Administration will also self-quarantine; all three are on the coronavirus task force.

The U.S. Centers for Disease Control and Prevention (CDC) on Saturday reported 1,274,036 cases of the new coronavirus, an increase of 25,996 cases from its previous count, and said the number of deaths had risen by 1,557 to 77,034.

IN 1993, 12-year-old Zoe Hitchman passed away after falling ill with meningitis.

The U.S. Centers for Disease Control and Prevention (CDC) on Saturday reported 1,274,036 cases of the new coronavirus, an increase of 25,996 cases from its previous count, and said the number of deaths had risen by 1,557 to 77,034.

The funding will be used by the company to expand its production capacity.

The post SG’s biodegradable plastic maker RWDC raises $133m in Series B round appeared first on DealStreetAsia.

Washington (AFP) - Orders for vaccines against diseases such as measles have declined since a national emergency was declared in the United States because of the coronavirus pandemic, the US Centers for Disease Control and Prevention said Friday.

The head of the Food and Drug Administration will also self-quarantine; all three are on the coronavirus task force.

All category MSEDCL consumers including the residential and CHS (Co-operative Housing society) consumers having bill amount 10,000 & above can now avail the facility of RTGS and NEFT along with the online bill payment options.

The MSEDCL consumers primarily pay their electricity bills through cheque even if the online facility is available. However, due to the corona virus pandemic, the lockdown has affected the banking transactions. Considering this situation, MSEDCL has given the option of RTGS and NEFT for consumers having a bill of 10,000 and above. Even the single and three phase residential consumers having a bill of 10,000 and above, can make payment through this system. Along with this, the consumers can make online payment through credit card, net banking, debit card, google pay, cash card, UPI, digital wallet etc.

MSEDCL is printing the bank details on the electricity bills of residential and CHS consumers whose bill is more than 10,000. These consumers can avail this facility by using the virtual account details of MSEDCL given on their bill in their RTGS and NEFT application they submit to their bank. Also, the consumer can make payment only in the account number given on their electricity bill.

Direct Link through SMS
To make payment remotely from their home, MSEDCL sends direct payment link via SMS to LT consumers. A direct payment link is being sent via SMS including the details of bill amount, due date, etc to the consumers who have registered their mobile number with MSEDCL. The consumer can make payment using this link. The consumers who have not yet registered their mobile number with MSEDCL can send a SMS through that number typing MREG (space) (12-digit consumer number) to 9930399303. Apart from this, the consumer can also register by logging on to MSEDCL website i.e. www.mahadiscom.in or MSEDCL's Mahavitaran Mobile app.

Catch up on all the latest Crime, National, International and Hatke news here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This seminar focused on overcoming challenges to private sector participation in infrastructure in Southern Africa.

Mexico’s 2013 telecom reform has brought tangible benefits, spurring competition that has increased access and brought down mobile Internet costs from among the highest in advanced economies to among the lowest.

Mexico’s 2013 telecom reform has brought tangible benefits, spurring competition that has increased access and brought down mobile Internet costs from among the highest in advanced economies to among the lowest.

Based on the OECD-UNODC-World Bank Anti-Corruption Ethics and Compliance Handbook, this webcast organised by KPMG offered an opportunity for attendees to learn about and understand the value of anti-corruption and ethics compliance best practices and how to use them to enhance their programmes.

Do today’s students really know how to work well together? For the first time ever, the Programme for International Student Assessment 2015 (otherwise known as PISA) examined students’ ability to collaborate to solve problems and the necessary social skills involved in that process.

The Teaching and Learning International Survey (otherwise known as TALIS) is a survey conducted every five years that asks teachers and school leaders from around the world about the working conditions and the learning environment in their schools.

Not every student’s brain works and learns in the same way. Classrooms are increasingly becoming more aware of what is known as "neurodiversity" among their students, a term used to describe neurodevelopmental disorders such as ADHD and ASD.

A new series offers a fascinating glimpse into lives lost to history

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.

2. At the outset, it is deemed useful to record that besides the two agreements both dated 1.4,2012 between the parties which are covered by present petition, the petitioner and a sister concern of the respondent namely, Mi Marathi Media Ltd. also had a similar agreement with the petitioner. Some of correspondences ayailable on record support the aforesaid fact and disclose common meetings on the issue of outstanding dues.

3. Against Mi Marathi Media Utd, alryost in similar factual situation, petitioner had preferred BP No. 39 of 2018 for claiming an amount of Rs. 1.31 crores approximately. After considering ali the relevant issues, that broadcasting petition alongwith BP No. 163 of 2018 was heard ex-parte and substantially allowed by a recent judgment and order of this Tribunal dated 14.2.2020. Learned counsel for the petitioner has placed strong reliance upon that judgment more so because this petition is also against the sister concern of Ml Marathi Media having aimest identical factual background and is also being heard ex-parte. This petition has been filed for a money decree for an arnount of Rs. 2,46,20,606/- and for pendente lite and future interest @ 18% ¢.a, 4, The petitioner is Union of india in the capacity of a service provider. The respondent, who is a broadcaster Heencee, is.alse a service previder. The respandent has been shawn ta be ef a "Hcencee" within the meaning of the term under the TRA! Act, 1997. The petition is, therefore, claimed ta be covered within the ambit of Section 14 of the TRAI Act.

2. The petitioner company carries on the business of receiving signals from broadcasters of various television channels and of redistributing the same through franchisee cable network. The respondent company carries on business as a broadcaster/content provider. Both the parties are service providers and as such amenable to the jurisdiction of this Tribunal.

3. Through this petition, the petitioner is seeking recovery of Rs.1,51,88,898.26p(Rupees One Crore Fifty One lakhs Eighty Eight Thousand Ninety Eight and Paise Twenty Six Only) said to be the outstanding dues inclusive of interest as on 09.02.2016 along with interest @ 18% till the date of realization from the respondent. The dues are towards carriage fee for the services availed by 3 the respondent from the petitioner for carriage of its television channel "Live India".

2. We heard the Learned Counsel for the parties. This application was filed by the Applicant in the matter of the grant of the mining lease to the Respondent No.1 for executing the construction work of the road from the Jaora-Piplodha-Jalandharkheda & Piploda - Sailana at the instance of the Respondent No. 8/Madhya Pradesh Road Development Corporation Ltd. (MPRDC). For the aforesaid purpose the Respondent No.1 was granted temporary mining lease in July, 2013 for mining of material i.e. stone/boulder and murrum from the land in Khasra no. 308/1/1/a, village Amba, Tahsil Sailana, District Ratlam. The question raised by the Applicant was looking to the close proximity to the site of the aforesaid mining lease granted to the Respondent No.1, to the Sailana Wildlife Sanctuary famous for the Lesser Floricon bird, commonly known as Kharmour which is reported to be on the verge of near extinction and the aforesaid Sanctuary is one of the few habitats left over for the breeding purpose preferred by this bird, would be extensively disturbed as a result of the mining activity in such close proximity of the Sanctuary as also the fact, as was revealed before the Tribunal during the hearing, that the extent of the area of the Sailana Wildlife Sanctuary was limited to just about 13 sq.km.

A journalist on an English-speaking Russian radio station made the extraordinary claim earlier this week and by Thursday it was gaining some traction on social media.

Simon Mayo reveals the secret of his and Mark Kermode's podcast success

There are hundreds of thousands of podcasts to choose from. Here, we've curated the best 100 from across a wide range of interests, from gardening to true crime

Senior Biju Janata Dal (BJD) leader and Chairman of the Western Odisha Development Council (WODC), Subash Chauhan died at a private hospital here on Sunday following a prolonged illness. He was 54. Chauhan, who was undergoing treatment for liver ailment was a bachelor and breathed his last in the morning, family sources said. Closely associated with the RSS and VHP for many years, the former national Convenor of the Bajrang Dal had quit the BJP and joined the Biju Janata Dal in the run-up to the 2019 general elections. Chauhan was subsequently appointed the chairman of WODC in September last year. A host of dignitaries including Odisha Chief Minister Naveen Patnaik and Union Ministers Dharmendra Pradhan and Pratap Sarangi condoled the demise of Chauhan describing it as a big loss for the state. Expressing deep grief, Patnaik said the contributions made by Chauhan for the welfare of the people will always be remembered by all in the state. Praying for peace for the ...

New Delhi is closer to accepting a progressive radio policy, but there is still more it can do. The India Together editorial.