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Speeding motorists taking advantage of deserted roads since the lockdown

Since the lockdown was enforced on 23 March there has been a 'sharp deterioration in driving behaviour, with a noticeable increase in speeding', according to telematics data.




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Ministers fear 'The Blob' - made up of political opponents - will sabotage reopening of schools

Ministers believe 'The Blob' - an army made up of political opponents and union barons - is colluding to politicise the coronavirus outbreak, The Mail on Sunday has learned.




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Ramsey and De Ligt are ready for centre stage at Juventus after an unsettled summer for new recruits

ALVISE CAGNAZZO IN ITALY: Aaron Ramsey has had his settling in period hampered by injury while Matthijs De Ligt found himself benched for their first match.




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Instagram hit: Shih tzu Paningning sleeps in unusual positions

Paningning, a shih tzu, sleeps flat on her back like a human and often drifts off in unusual places. Owner Janess Cua from the Philippines shared photos of the puppy which have since gone viral.




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Khloe Kardashian elaborately toilet papers sister Kourtney's mansion amid worldwide shortage

Amid the worldwide toilet paper shortage, Khloé Kardashian plastered her older sister Kourtney's home with the highly sought-after paper good. 




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Kaia Gerber is 'grateful to be able to stay active' in lockdown as she flaunts her abs on Instagram

Kaia Gerber was recently deemed part of fashion's 'new wave of top-tier models.'




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Iggy Azalea shows off her flat stomach on Instagram amid baby rumours

Iggy Azalea has made a surprise return to Instagram to show off her washboard abs, following unconfirmed reports she had a baby with Playboi Carti less than two weeks ago. 




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Samantha Armytage rages at 'scammers' using her name and image on fake adverts

Samantha Armytage has hit out at 'scammers' using her name on bogus adverts. 




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Atletico Madrid 'set £20m price tag on Kieran Trippier' amid Premier League interest

The 29-year-old moved to the Wanda Metropolitano last summer having fallen out of favour in north London, with the La Liga side splashing £20million on the England international.




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Manchester United 'slap astonishing £35m price tag on Paris Saint-Germain target Diogo Dalot'

The 21-year-old right-back joined the club from Porto in 2018 for around £18m.but he has had few opportunities this season due to sensational form of Aaron Wan-Bissaka.




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Why Tagore?


Despite their love for and knowledge of Tagore, the intellectuals of Bengal have sold him short. They have provincialised and parochialised Tagore; as a result, this thinker whose ideas extended well beyond Bengal has been turned into a local hero, writes Ramachandra Guha.




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Pune: Only 0.36% tested for contagion in PMC limits

Around 12,000 people have been tested for coronavirus infection in the PMC limits so far, accounting for just 0.35% of the total population of 33 lakh.




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Senior UK medic confident "R" contagion number below 1 across country

Britain's deputy chief medical officer said on Saturday he was confident the coronavirus "R" number, a measure of the rate of contagion, was below 1 across the United Kingdom.




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Pangolins may possess evolutionary advantage against coronavirus: Study

London, May 8: The anteater-like mammals, pangolins, possess an evolutionary advantage against coronavirus, according to researchers, who say that understanding the animal's immune system may help develop new treatment options for COVID-19. According to the scientists from the Medical




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Chahatt Khanna Deactivates Instagram Account After Lashing Out At Trolls; Hints She’s Depressed!

Bade Achhe Lagte Hain fame Chahatt Khanna is a single mother with two beautiful girls, Zohar and Amaira. Recently, the actress lashed out at online trolls criticising her for being a single mother. She shared a few notes on her Instagram




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Shocking! Vikas Gupta Deletes All His Instagram Posts Just A Day After His Birthday

The producer and Bigg Boss 11's mastermind, Vikas Gupta is quite active on social media. He has been sharing amazing pictures and videos on his Instagram account. The producer recently (May 7, 2020) celebrated his birthday and the next day, he




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Vinay Rajkumar On COVID-19 Lockdown: ‘As Actors, We Don't Have Work From Home Advantage’

Vinay Rajkumar recently unveiled the teaser and posters of his upcoming movies (Gramayana and 10) as birthday gifts to his fans. The actor who turned 31-years-old on May 7, also opened up about the life under lockdown in a recent interview




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గుడ్‌న్యూస్!: 29 వరకు FASTagలు ఉచితం, ఎలా తీసుకోవలంటే?

FASTagను ఇంకా కొనుగోలు చేయలేదా? అయితే మీకో గుడ్‌న్యూస్! జాతీయ రహదారులపై ఎలక్ట్రానిక్ టోల్ వసూళ్ల కోసం కేంద్ర ప్రభుత్వం FASTagను తీసుకు వచ్చిన విషయం తెలిసిందే. అయితే ఇప్పుడు ఉచితంగా పొందవచ్చు. ఈ అవకాశాన్ని కేంద్ర ప్రభుత్వం ఓ పదిహేను రోజుల పాటు కల్పిస్తోంది. ఎలక్ట్రానిక్ టోల్ విధానాన్ని మెరుగుపరచడం కోసం FASTagలను ఉచితంగా అందించాలని




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Chinmayi Sripada On Fighting Against Online Abuse: I Tag The Cyber Cell

Singer Chinmayi Sripada has always been active on social media and never forgets to raise her voice on social issues. For the past three weeks, Chinmayi is also using her singing talent in raising funds for the families of daily wage




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Cycling: Vuelta cancels stages in Portugal amid COVID-19 crisis

This year's Tour of Spain will not go through Portugal as planned because of the COVID-19 crisis, organisers said on Saturday.




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The circle of the sciences: with an introductory discourse of the objects, pleasures, and advantages of science / by Henry, Lord Brougham ; edited by James Wylde

Archives, Room Use Only - Q160.W95 1862




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Traders found cashing in on shortage of construction materials

VACB squads to conduct checks across State




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Stranded migrant workers stage protest in Mangaluru, demand to be sent back home




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Vizag gas victims stage protest at plant with dead bodies




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French Open 2020 could be staged behind closed doors: Chief Guidicelli

The spread of the coronavirus has halted all tennis events since mid-March and will not resume until July 13 at the earliest




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Cowboys rule out rescinding Dak Prescott franchise tag

The Cowboys have giveth, but they will not be taketh-ing away. The labor deal allowed the Cowboys to use the franchise tag to keep quarterback Dak Prescott from becoming a free agent in March. The labor deal also allows the Cowboys to rescind the franchise tender at any time before he accepts it. Appearing on [more]




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Dental hostel tagged containment zone

Dental hostel tagged containment zone




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The end-tag open (ETAGO) delimiter

According to HTML4, the first occurrence of the character sequence



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TN: 800 workers stage protest at nuclear plant




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Amid Covid scare, Bengal celebrates Tagore's 159th birth anniversary




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TMC leaders hit out at Shah, say West Bengal has seven-stage programme to bring back people




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AITUC to stage demonstration

THANJAVUR The All India Trade Union Congress will be organising a demonstration on May 11 to press the Union and State governments to expedite the pro




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Patients housed in Corpn. care centres stage protests

Asymptomatic persons demand better facilities




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Senior UK medic confident "R" contagion number below 1 across country

Senior UK medic confident "R" contagion number below 1 across country




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Lockdown in Tamil Nadu: 800 guest workers stage protest at Kudankulam Nuclear Power Plant, attack cops

Lockdown in Tamil Nadu: 800 guest workers stage protest at Kudankulam Nuclear Power Plant, attack cops




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Punjab Governor visits vintage car rally in Gurugram




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Ludhiana faces medicine shortage as wholesale supply stops




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Amid labour shortage, Punjab advances paddy sowing date




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Russo Brothers to recommend and discuss movies as a part of Instagram series




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Mutagenesis facilitated crystallization of GLP-1R

The class B family of G-protein-coupled receptors (GPCRs) has long been a paradigm for peptide hormone recognition and signal transduction. One class B GPCR, the glucagon-like peptide-1 receptor (GLP-1R), has been considered as an anti-diabetes drug target and there are several peptidic drugs available for the treatment of this overwhelming disease. The previously determined structures of inactive GLP-1R in complex with two negative allosteric modulators include ten thermal-stabilizing mutations that were selected from a total of 98 designed mutations. Here we systematically summarize all 98 mutations we have tested and the results suggest that the mutagenesis strategy that strengthens inter-helical hydro­phobic interactions shows the highest success rate. We further investigate four back mutations by thermal-shift assay, crystallization and molecular dynamic simulations, and conclude that mutation I1962.66bF increases thermal stability intrinsically and that mutation S2714.47bA decreases crystal packing entropy extrinsically, while mutations S1932.63bC and M2333.36bC may be dispensable since these two cysteines are not di­sulfide-linked. Our results indicate intrinsic connections between different regions of GPCR transmembrane helices and the current data suggest a general mutagenesis principle for structural determination of GPCRs and other membrane proteins.




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Miniaturized GPS Tags Allow Tracking of Small Songbirds for first time

For the first time, researchers at the Smithsonian Conservation Biology Institute’s Migratory Bird Center have accurately tracked small migratory ovenbirds (Seiurus aurocapilla) to their tropical […]

The post Miniaturized GPS Tags Allow Tracking of Small Songbirds for first time appeared first on Smithsonian Insider.




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This simple trick helped fix a wildlife water shortage in Cambodia

It is a simple solution to a wildlife water shortage. During the annual dry season [November through April] in a protected forest in eastern Cambodia, […]

The post This simple trick helped fix a wildlife water shortage in Cambodia appeared first on Smithsonian Insider.





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Whale tagging in Southeast Pacific provides data for species protection

Whales from both poles migrate long distances to breed in tropical waters. Smithsonian scientist Hector M. Guzman and Fernando Félix at the Salinas Whale Museum […]

The post Whale tagging in Southeast Pacific provides data for species protection appeared first on Smithsonian Insider.




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Protecting Puerto Rico’s heritage from another disaster

When a natural disaster strikes, it devastates lives and homes, and can even destroy a culture’s identity and history. After a disaster, humanitarian response is […]

The post Protecting Puerto Rico’s heritage from another disaster appeared first on Smithsonian Insider.



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Polar-orbiting satellite captures amazing X-ray footage of solar eclipse

The moon passed between the Earth and the sun on Thursday, Oct. 23. While avid stargazers in North America looked up to watch the spectacle, the […]

The post Polar-orbiting satellite captures amazing X-ray footage of solar eclipse appeared first on Smithsonian Insider.




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Vista SP1 fails at Stage 3 of 3 100%.




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Messages of Condolence and Support From Representatives of Academies and Research Institutions in the Wake of Attacks on the World Trade Center and Pentagon

Representatives from academies and research organizations around the world sent messages of condolence and support to members, officials and staff of the U.S. National Academies in the wake of terrorist attacks on the World Trade Center and the Pentagon. The following are excerpts from some of these messages.




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Americans Have Worse Health Than People in Other High-Income Countries - Health Disadvantage Is Pervasive Across Age and Socio-Economic Groups

On average, Americans die sooner and experience higher rates of disease and injury than people in other high-income countries, says a new report from the National Research Council and Institute of Medicine.