Extreme heat is an invisible but increasingly tangible climate risk. It varies by time and place and has wide-reaching but unequal impacts, particularly to women and vulnerable people. As global temperatures rise, extreme heat events (heat waves) are becoming more frequent and severe.

This report outlines the cascading environmental, social, and economic impacts of aquatic biodiversity loss in Southeast Asia and recommends ways to develop scalable projects that tackle river pollution and support sustainable development.

Blackworms are ultra-fast swimmers, and they tangle up into worm balls to protect themselves from predators – but leeches have an ingenious method of catching them called “spiral entombment”

A camera trap at an Australian nature refuge has captured a boisterous interaction between a northern hairy-nosed wombat and an echidna

A pair of ctenophores, or comb jellies, can fuse their bodies together, merging their digestive and nervous systems, without any issues with immune rejection

An urn found in a tomb in Spain contained the cremated remains of a man, a gold ring and about 5 litres of liquid, which has been identified as now-discoloured white wine

Title: New Drug Combo Helps Hard-to-Treat Hepatitis C
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Title: Read Food Labels to Combat Childhood Obesity
Category: Health News
Created: 8/22/2014 5:36:00 PM
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Mapping transcriptomic variations using either short- or long-read RNA sequencing is a staple of genomic research. Long reads are able to capture entire isoforms and overcome repetitive regions, whereas short reads still provide improved coverage and error rates. Yet, open questions remain, such as how to quantitatively compare the technologies, can we combine them, and what is the benefit of such a combined view? We tackle these questions by first creating a pipeline to assess matched long- and short-read data using a variety of transcriptome statistics. We find that across data sets, algorithms, and technologies, matched short-read data detects ~30% more splice junctions, such that ~10%–30% of the splice junctions included at ≥20% by short reads are missed by long reads. In contrast, long reads detect many more intron-retention events and can detect full isoforms, pointing to the benefit of combining the technologies. We introduce MAJIQ-L, an extension of the MAJIQ software, to enable a unified view of transcriptome variations from both technologies and demonstrate its benefits. Our software can be used to assess any future long-read technology or algorithm and can be combined with short-read data for improved transcriptome analysis.

BACKGROUND:This study sought to estimate the overall cumulative incidence and odds of Hospital-acquired venous thromboembolism (VTE) among critically ill children with and without exposure to invasive ventilation. In doing so, we also aimed to describe the temporal relationship between invasive ventilation and hospital-acquired VTE development.METHODS:We performed a retrospective cohort study using Virtual Pediatric Systems (VPS) data from 142 North American pediatric ICUs among children < 18 y of age from January 1, 2016–December 31, 2022. After exclusion criteria were applied, cohorts were identified by presence of invasive ventilation exposure. The primary outcome was cumulative incidence of hospital-acquired VTE, defined as limb/neck deep venous thrombosis or pulmonary embolism. Multivariate logistic regression was used to determine whether invasive ventilation was an independent risk factor for hospital-acquired VTE development.RESULTS:Of 691,118 children studied, 86,922 (12.4%) underwent invasive ventilation. The cumulative incidence of hospital-acquired VTE for those who received invasive ventilation was 1.9% and 0.12% for those who did not (P < .001). The median time to hospital-acquired VTE after endotracheal intubation was 6 (interquartile range 3–14) d. In multivariate models, invasive ventilation exposure and duration were each independently associated with development of hospital-acquired VTE (adjusted odds ratio 1.64 [95% CI 1.42–1.86], P < .001; and adjusted odds ratio 1.03 [95% CI 1.02–1.03], P < .001, respectively).CONCLUSIONS:In this multi-center retrospective review from the VPS registry, invasive ventilation exposure and duration were independent risk factors for hospital-acquired VTE among critically ill children. Children undergoing invasive ventilation represent an important target population for risk-stratified thromboprophylaxis trials.

BACKGROUND AND PURPOSE:

Preoperative assessment of meningioma consistency is beneficial for optimizing surgical strategy and prognosis of patients. We aim to develop a noninvasive prediction model for meningioma consistency utilizing MR elastography and DTI.

BACKGROUND AND PURPOSE:

Mechanical thrombectomy is a fundamental intervention for acute ischemic stroke treatment. While conventional techniques are effective, cyclic aspiration (CyA) shows potential for better recanalization rates. We aim to investigate factors affecting CyA and compare them with static aspiration (StA).

BACKGROUND AND PURPOSE:

Reocclusion after treatment is a concern in endovascular therapy for isolated intracranial atherothrombotic stroke-related large-vessel occlusion (AT-LVO). However, the optimal endovascular therapy technique for AT-LVO has not yet been investigated. This study evaluated the optimal endovascular therapy technique for AT-LVO in a real-world setting.

At least 231 people were killed and hundreds more wounded after a massive truck bomb on Saturday struck Somalia’s capital city of Mogadishu.

The Somali government has blamed the al-Qaida-linked militant group al-Shabab for the attack, and called it the deadliest ever to hit the nation.

The blast took place outside the Safari Hotel, where rescue workers dug through the rubble of collapsed buildings overnight in search of survivors. Witnesses described a devastating scene with large-scale carnage, as doctors worked feverishly to attend to the dead and injured, many badly burned.

“The hospital is overwhelmed by both dead and wounded,” Dr. Mohamed Yusuf, the director of Medina hospital located near the blast, told the Associated Press. “We also received people whose limbs were cut away by the bomb. This is really horrendous, unlike any other time in the past.”

Photos and videos of the bombing, which took place on a busy street near a section of the city housing foreign embassies, showed collapsed walls, twisted metal, and sporadic fires spewing smoke. The Qatari government said its embassy was “severely damaged” in the strike.

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Family members searched through the wreckage and waited at local hospitals with the hopes of finding relatives who survived the bombing.

Somali President Mohamed Abdullahi Mohamed announced three days of mourning. The attacks received international condemnation, including from the United States.

The post Hundreds dead after massive truck bomb strikes Mogadishu appeared first on PBS NewsHour.

WASHINGTON — Secretary of State Rex Tillerson says diplomatic efforts aimed at resolving the North Korean crisis “will continue until the first bomb drops.”

That statement comes despite President Donald Trump’s tweets a couple of weeks ago that his chief envoy was “wasting his time” trying to negotiate with “Little Rocket Man,” a mocking nickname Trump has given the nuclear-armed nation’s leader, Kim Jong Un.

“I think he does want to be clear with Kim Jong Un and that regime in North Korea that he has military preparations ready to go and he has those military options on the table. And we have spent substantial time actually perfecting those,” Tillerson told CNN’s “State of the Union” on Sunday. “But be clear: The president has also made clear to me that he wants this solved diplomatically. He’s not seeking to go to war.”

Recent mixed messaging from the top of the U.S. government has raised concerns about the potential for miscalculation amid the increasingly bellicose exchange of words by Trump and the North Korean leader.

Trump told the U.N. General Assembly last month that if the U.S. is “forced to defend itself or its allies, we will have no choice but to totally destroy North Korea.” Trump also tweeted that Korea’s leadership “won’t be around much longer” if it continued its provocations, a declaration that led the North’s foreign minister to assert that Trump had “declared war on our country.”

Tillerson acknowledged during a recent trip to Beijing that the Trump administration was keeping open direct channels of communications with North Korea and probing the North’s willingness to talk. He provided no elaboration about those channels or the substance of any discussions.

Soon after, Trump took to Twitter, saying he had told “our wonderful Secretary of State, that he is wasting his time trying to negotiate with Little Rocket Man … Save your energy Rex, we’ll do what has to be done!” Trump offered no further explanation, but he said all military options are on the table for dealing with North Korea’s nuclear and missile programs.

Analysts have speculated about whether the president and his top diplomat were playing “good cop, bad cop” with North Korea, and how China might interpret the confusing signals from Washington. Beijing is the North’s main trading partner, and the U.S. is counting on China to enforce U.N. sanctions.

“Rest assured that the Chinese are not confused in any way what the American policy towards North Korea (is) or what our actions and efforts are directed at,” Tillerson said.

Asked if Trump’s tweets undermined Tillerson, the secretary said: “I think what the president is doing is he’s trying to motivate action on a number of people’s part, in particular the regime in North Korea. I think he does want to be clear with Kim Jong Un and that regime in North Korea that he has military preparations ready to go and he has those military options on the table and we have spent substantial time perfecting those.”

He added that Trump “has made it clear to me to continue my diplomatic efforts, which we are, and I’ve told others those diplomatic efforts will continue until the first bomb drops.”

North Korea has launched missiles that potentially can strike the U.S. mainland and recently conducted its largest ever underground nuclear explosion. It has threatened to explode another nuclear bomb above the Pacific.

The post Rex Tillerson says continue diplomacy with North Korea ‘until first bomb drops’ appeared first on PBS NewsHour.

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JUDY WOODRUFF: And in the day’s other news: More than 300 people are now confirmed dead after Saturday’s massive truck bombing in Somalia, one of the world’s worst attacks in years.

Nearly 400 more were wounded. The government blamed the al-Qaida-linked Al-Shabaab group. Rescue crews today searched for survivors at the scene of the bombing, a crowded street in the capital, Mogadishu. With dozens still missing, officials say they expect the death toll to rise.

OSMAN LIBAH IBRAHIM, Deputy Minister for Natural Resources, Somalia (through interpreter): More bodies are gradually being found and removed from the rubble. There are other people who are under the rubble. We have heard them as they scream for help. My biggest worry is that even the wounded are succumbing to their injuries.

JUDY WOODRUFF: The attack happened two days after Somalia’s defense minister and army chief resigned for undisclosed reasons.

There’s been yet another shift to the right in European politics; 31-year-old conservative Sebastian Kurz, Austria’s foreign minister, is set to become that country’s next leader. But he’s short of a majority in Parliament and will likely form a coalition with the far-right Freedom Party. It was founded by ex-Nazis in the 1950s.

Kurz has called for the European Union to focus more on internal trade and securing borders. He celebrated in Vienna.

SEBASTIAN KURZ, Austrian People’s Party (through interpreter): I have a big request for you. Use today to celebrate. You all have earned it through hard work and dedication. At the same time, I need to tell you that tomorrow the work starts. We didn’t just run to win the elections. We did so to bring Austria back to the top. We ran in this election to achieve real change.

JUDY WOODRUFF: A final result in the election is likely to be decided on Thursday.

Wildfires that broke out over the weekend in Portugal have killed at least 35 people, including a one-month-old infant. Today, more than 5,300 firefighters with some 1,600 vehicles were battling the fires, some of which officials say were started by arsonists. Wildfires have also left at least four people dead in neighboring Spain.

Army Sergeant Bowe Bergdahl pleaded guilty today to desertion and misbehavior before the enemy. He was captured by the Taliban in 2009, after leaving his post in Afghanistan. It prompted an intense search and a prisoner swap. Bergdahl appeared before a military judge in Fort Bragg, North Carolina, today. The 31-year-old could be sentenced to life in prison. He said his actions were very inexcusable, adding he didn’t — quote — “think there’d be any reason to pull off a crucial mission to look for one guy.”

The truck driver in deadly immigrant smuggling run has pleaded guilty in court. San Antonio police found at least 39 immigrants, 10 of whom died, packed into a sweltering semi-trailer last year and died. The driver, James Matthew Bradley Jr., pleaded to conspiracy and transporting immigrants, resulting in death. He faces now up to life in prison.

A New Jersey man has been convicted of planting two pressure-cooker bombs on New York City streets last year. Ahmed Khan Rahimi faces a maximum sentence of life in prison for charges including using a weapon of mass destruction. One of the bombs exploded in Manhattan’s Chelsea neighborhood, wounding 30. The second didn’t detonate. Officials said Rahimi was inspired by ISIS and al-Qaida.

JOHN MILLER, Deputy Commissioner, NYPD Intelligence & Counterterrorism: Ahmed Khan Rahimi learned a lesson which we keep reminding people of. This is the wrong place to try and carry out an act of terrorism. Witnesses will come forward, evidence will be developed, arrests will be made, prosecutions will be brought forth, and they will be successful.

JUDY WOODRUFF: Prosecutors said Rahimi also planted a pipe bomb in Seaside Heights, New Jersey, but no one was injured.

Colin Kaepernick has filed a grievance against the national football league. The former San Francisco 49ers quarterback says that he remains unsigned due to collusion by team owners over his national anthem protests. Kaepernick sparked a debate when he kneeled during the anthem last year, protesting police mistreatment of African-Americans.

On Wall Street today, the Dow Jones industrial average gained 85 points to close at 22957. The Nasdaq rose 18. And the S&P 500 added four.

It was a milestone day in the world of astronomy. For the first time, researchers say they have detected gravitational waves with a flash of light from the same cosmic event. The dual observation supports Albert Einstein’s general theory of relativity. The ripples in space and the light burst were caused by the collision of two neutron stars. They were first detected in August.

The post News Wrap: Dozens missing after deadly Mogadishu truck bombing appeared first on PBS NewsHour.

LEADING Aboriginal academic Marcia Langton has blasted Bill Shorten over his claim Labor could sign a treaty with Indigenous Australians.

Kelley hoards all the PS5s. Chris needs a build for the I'm Bad playstyle. And Josh gets treatment for his cat's demon tapeworm.

The post RPG Cast – Episode 645: “Rob Zombie’s Drag-Gula Lost” appeared first on RPGamer.

I didn’t get much further in the extremely popular beta for the haute-couture-asaurus action of Monster Hunter Wilds than perfecting the exact orange-to-white ratio of my cat. Not because I wasn’t having fun, but because I immediately started looking up GPU prices after playing for ten minutes. As such, I didn’t spend enough time with the combat to get a proper feel for it. Cultural osmosis has once again allowed me to form an uneducated take, however, and I’m getting the sense there’s been some mixed reactions re: bonk quality. According to a clip shared on X by user Blue Stigma, there's a good reason for those misgivings. It's all about frames, you see.

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Foxhole is one of my favourite games to read about, even if I don't play it. It's a massively multiplayer World War 2 game, viewed from above, where battlefield logistics matters as much as aiming and flanking. Its developers have just announced a major new update coming next summer, Foxhole: Airborne, which adds planes to the game for the first time.

Planes, in a topdown MMO? It makes a little more sense if you watch the trailer.

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‘Battle of Technologies’ sees electric vehicles and combustion cars compete at the highest level. Who will win?

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Black Ops 6 is here, and it's Black Ops 2's anniversary, so what better time than to rank the Call of Duty Black Ops titles? Here's our ranking of every mainline version.

Depending on PC config you may see up to a 30fps uplift with anti-tamper tech ditched.

EPICS in IEEE, a service learning program for university students supported by IEEE Educational Activities, offers students opportunities to engage with engineering professionals and mentors, local organizations, and technological innovation to address community-based issues.

The following two environmentally focused projects demonstrate the value of teamwork and direct involvement with project stakeholders. One uses smart biodigesters to better manage waste in Colombia’s rural areas. The other is focused on helping Turkish olive farmers protect their trees from climate change effects by providing them with a warning system that can identify growing problems.

No time to waste in rural Colombia

Proper waste management is critical to a community’s living conditions. In rural La Vega, Colombia, the lack of an effective system has led to contaminated soil and water, an especially concerning issue because the town’s economy relies heavily on agriculture.

The Smart Biodigesters for a Better Environment in Rural Areas project brought students together to devise a solution.

Vivian Estefanía Beltrán, a Ph.D. student at the Universidad del Rosario in Bogotá, addressed the problem by building a low-cost anaerobic digester that uses an instrumentation system to break down microorganisms into biodegradable material. It reduces the amount of solid waste, and the digesters can produce biogas, which can be used to generate electricity.

“Anaerobic digestion is a natural biological process that converts organic matter into two valuable products: biogas and nutrient-rich soil amendments in the form of digestate,” Beltrán says. “As a by-product of our digester’s operation, digestate is organic matter that can’t be transferred into biogas but can be used as a soil amendment for our farmers’ crops, such as coffee.

“While it may sound easy, the process is influenced by a lot of variables. The support we’ve received from EPICS in IEEE is important because it enables us to measure these variables, such as pH levels, temperature of the reactor, and biogas composition [methane and hydrogen sulfide]. The system allows us to make informed decisions that enhance the safety, quality, and efficiency of the process for the benefit of the community.”

The project was a collaborative effort among Universidad del Rosario students, a team of engineering students from Escuela Tecnológica Instituto Técnico Central, Professor Carlos Felipe Vergara, and members of Junta de Acción Comunal (Vereda La Granja), which aims to help residents improve their community.

“It’s been a great experience to see how individuals pursuing different fields of study—from engineering to electronics and computer science—can all work and learn together on a project that will have a direct positive impact on a community.” —Vivian Estefanía Beltrán

Beltrán worked closely with eight undergraduate students and three instructors—Maria Fernanda Gómez, Andrés Pérez Gordillo (the instrumentation group leader), and Carlos Felipe Vergara-Ramirez—as well as IEEE Graduate Student Member Nicolás Castiblanco (the instrumentation group coordinator).

The team constructed and installed their anaerobic digester system in an experimental station in La Vega, a town located roughly 53 kilometers northwest of Bogotá.

“This digester is an important innovation for the residents of La Vega, as it will hopefully offer a productive way to utilize the residual biomass they produce to improve quality of life and boost the economy,” Beltrán says. Soon, she adds, the system will be expanded to incorporate high-tech sensors that automatically monitor biogas production and the digestion process.

“For our students and team members, it’s been a great experience to see how individuals pursuing different fields of study—from engineering to electronics and computer science—can all work and learn together on a project that will have a direct positive impact on a community. It enables all of us to apply our classroom skills to reality,” she says. “The funding we’ve received from EPICS in IEEE has been crucial to designing, proving, and installing the system.”

The project also aims to support the development of a circular economy, which reuses materials to enhance the community’s sustainability and self-sufficiency.

Protecting olive groves in Türkiye

Türkiye is one of the world’s leading producers of olives, but the industry has been challenged in recent years by unprecedented floods, droughts, and other destructive forces of nature resulting from climate change. To help farmers in the western part of the country monitor the health of their olive trees, a team of students from Istanbul Technical University developed an early-warning system to identify irregularities including abnormal growth.

“Almost no olives were produced last year using traditional methods, due to climate conditions and unusual weather patterns,” says Tayfun Akgül, project leader of the Smart Monitoring of Fruit Trees in Western Türkiye initiative.

“Our system will give farmers feedback from each tree so that actions can be taken in advance to improve the yield,” says Akgül, an IEEE senior member and a professor in the university’s electronics and communication engineering department.

“We’re developing deep-learning techniques to detect changes in olive trees and their fruit so that farmers and landowners can take all necessary measures to avoid a low or damaged harvest,” says project coordinator Melike Girgin, a Ph.D. student at the university and an IEEE graduate student member.

Using drones outfitted with 360-degree optical and thermal cameras, the team collects optical, thermal, and hyperspectral imaging data through aerial methods. The information is fed into a cloud-based, open-source database system.

Akgül leads the project and teaches the team skills including signal and image processing and data collection. He says regular communication with community-based stakeholders has been critical to the project’s success.

“There are several farmers in the village who have helped us direct our drone activities to the right locations,” he says. “Their involvement in the project has been instrumental in helping us refine our process for greater effectiveness.

“For students, classroom instruction is straightforward, then they take an exam at the end. But through our EPICS project, students are continuously interacting with farmers in a hands-on, practical way and can see the results of their efforts in real time.”

Looking ahead, the team is excited about expanding the project to encompass other fruits besides olives. The team also intends to apply for a travel grant from IEEE in hopes of presenting its work at a conference.

“We’re so grateful to EPICS in IEEE for this opportunity,” Girgin says. “Our project and some of the technology we required wouldn’t have been possible without the funding we received.”

A purpose-driven partnership

The IEEE Standards Association sponsored both of the proactive environmental projects.

“Technical projects play a crucial role in advancing innovation and ensuring interoperability across various industries,” says Munir Mohammed, IEEE SA senior manager of product development and market engagement. “These projects not only align with our technical standards but also drive technological progress, enhance global collaboration, and ultimately improve the quality of life for communities worldwide.”

For more information on the program or to participate in service-learning projects, visit EPICS in IEEE.

On 7 November, this article was updated from an earlier version.

Growing research indicates a pregnant woman’s stress level and overall mental well-being can affect fetal and child development, yet access to prenatal mental health care remains inadequate

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The blackest of Fridays is nearly upon us and companies have already begun rolling out the deals to separate consumers from their bank accounts. Here’s one for a well-regarded and budget-friendly robovac. The iRobot Roomba Essential Vac is on sale for just $140, which is a discount of 44 percent. The regular price is $250.

The Essential Vac features a similar design to the iRobot Roomba 694, which topped our list of the best budget robot vacuums. This one includes a three-stage cleaning system that works on both carpet and hard floors. It features the same smart navigation system as other iRoomba vacuums, so it’ll avoid stairs and work its way around items of furniture.

Despite being a budget-friendly robovac, there are some modern flourishes. The vacuum will automatically return to the charging station when the battery runs low, which is always nice. It also integrates with the Roomba app for setting cleaning schedules and for building a custom map of the home.

The battery life sits at around two hours, which is a decent metric for the price. That should be more than enough time to thoroughly clean a medium-sized home. The major caveat here is that this is a budget robovac, so it doesn’t mop and it doesn’t ship with a large debris canister. Still, the price is right for those curious about eliminating sweeping from that to-do list.

Check out all of the latest Black Friday and Cyber Monday deals here.

Amoureux du sport, Sylvain Croteau a décidé de consacrer sa carrière, depuis 10 ans, à prévenir et à contrer la violence et les abus dans ce monde.

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India's capital unveiled plans Friday to fly special drones to clear pollution from its smog-choked skies - a plan derided by experts as another "band-aid" solution to a public health crisis. New Delhi and the surrounding metropolitan area, home to more than 30 million people, consistently tops world rankings for air pollution in winter. The smog is blamed for thousands of premature de

L’ex-premier ministre de la Colombie-Britannique John Horgan est décédé à l’âge de 65 ans après une bataille contre le cancer.

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This book is intended to advance the next phase of the U.S.-Colombia relationship. In a rapidly changing world, the following chapters present a roadmap for a new type of engagement that challenges our ambitions and extends the ties that bind our countries. 

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As Israel continues to block lifesaving humanitarian aid from entering northern Gaza, humanitarian organizations are describing its siege as “apocalyptic” and warning of mass Palestinian starvation and death. “The situation is absolutely desperate,” says Rachael Cummings of the aid group Save the Children International. Cummings joins us from Deir al-Balah in central Gaza, where aid organizations have been halted from entering the north. She responds to news of Israel’s bombing of a polio vaccination center in an area that had been marked for an official humanitarian pause, and the Knesset’s vote to ban the U.N. relief agency UNRWA.

Comet 12P/Pons-Brooks will make its closest approach to the sun this April—right after North America is treated to a total solar eclipse

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