COVID-19 antibodies have been found in blood samples as early as September, 2019. China knew about the virus' transmission to humans months before it announced such to the world. Why has the media and our government not investigated this gross negligence, if not mass murder? Continue reading →

I've kind of been ignoring this blog for a while. That's nothing new... there have been multi-year periods with no posts. I'm still writing stuff...

Exploring Europa and defending Earth.

Matteo Simoni over geschrapte naaktscènes in ‘Callboys’: “Jan Eelen pakte mijn ‘jos’ en zwierde hem weg”  Het Laatste Nieuws

September is Campus Fire Safety Month and this year the National Fire Protection Association (NFPA) and The Center for Campus Fire Safety (The Center) are working together to promote their national Campus Fire Safety for Students campaign. The campaign raises awareness about the dangers of fires among college-aged students who live in on- and off-campus college housing.

Older than easy but not yet novels. The fact of the matter is that while Easy Books are hard to write, Early Chapter Books are hard to categorize. They're also ideal bedtime books for older children, which means that with the European imports you get a lot of experimentation. American early chapter books are pretty much just written to please. Here then are the books written with 6-9 year olds in mind.

The Short Breaks Fund helping to make breaks better and brighter for unpaid carers and cared-for people in Scotland. Launched in 2010 for one year, the fund has now been running for five years and has proved to be a lifeline for many carers. During the past five years the Scottish Government, through Shared Cared Scotland has distributed 12,547,409 to 697 projects to deliver innovative, tailor made breaks to groups and individuals.

Hardcover, Kindle, Audiobook – March 3, 2020

The post Soviet Helicopters appeared first on English Russia.

Come one, come all! nycdevops does its first virtual meetup! All are invited!

• Speaker: Adarsh Shah
• Topic: "Continuous Delivery for Machine Learning"
• Time: Thursday, September 17, 2020, 5-630 PM
• Link: https://www.meetup.com/nycdevops/events/272914068/

Hope to see you there!

The evolution of planet Earth over 4.5 billion years.

Police revealed Tuesday they had infiltrated and taken down an encrypted chat app called Ghost used by criminals across the world.

This month, we’ll give AI a rest. Alex Russell has finished an excellent series of posts titled “Reckoning.” It’s a must-read for web developers. If you want to understand why our networks and laptops are much faster than they were 15 or 20 years ago, but the web is slower, it comes down to one […]

A Minnessota maker named Caleb Olson built the Poopcopter, an autonomous drone that seeks out dog-doo and retrieves it for disposal.

He describes it as the "world's first aerial bound self-guided dog poop removal system." See it in action below.

"The Poopcopter is capable of scanning areas defined by a user, your backyard for example, and as it scans it's performing real-time computer vision using the camera which is inside the drone," Olson says. — Read the rest

The post The Poopcopter is a DIY autonomous drone that finds and collects dog-doo appeared first on Boing Boing.

Instant Reaction: Mortgage Rates, September 5, 2024

Instant Reaction: Jobs, September 6, 2024

Ah, September — one of the most beautiful months of the year, and one of the best months to travel. I definitely put this month to good use. This was a busy September for me, beginning with my getaway to South Moravia in the Czech Republic, with a 12-day trip to the Basque Country and […]

The post AK Monthly Recap: September 2024 appeared first on Adventurous Kate.

Mark Fisher was co-founder of the Rhode Island chapter of BLM. He voted for Joe Biden in 2020. Does he have buyers remorse? Yeah, you could say so. His viral video is causing a stir... but there's more to that story.

The post Former BLM Chapter Co-Founder Switches To Trump In ’24 … What Changed His Mind? appeared first on Clash Daily.

Long hailed as dancehall's most controversial figure, Vybz Kartel has always commanded the spotlight with his edgy lyrics and unfiltered persona. But since his release from prison in July, Kartel has begun to show a surprising transformation that'...

Radiolabeled small-molecule DOTA-haptens can be combined with antitumor/anti-DOTA bispecific antibodies (BsAbs) for pretargeted radioimmunotherapy (PRIT). For optimized delivery of the theranostic - and β-emitting isotope ¹⁷⁷Lu with DOTA-based PRIT (DOTA-PRIT), bivalent Gemini (DOTA-Bn-thiourea-PEG4-thiourea-Bn-DOTA, aka (3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(DOTA-benzyl thiourea)) was developed. Methods: Gemini was synthesized by linking 2 S-2-(4-isothiocyanatobenzyl)-DOTA molecules together via a 1,14-diamino-PEG4 linker. [¹⁷⁷Lu]Lu-Gemini was prepared with no-carrier-added ¹⁷⁷LuCl₃ to a molar-specific activity of 123 GBq/μmol and radiochemical purity of more than 99%. The specificity of BsAb-¹⁷⁷Lu-Gemini was verified in vitro. Subsequently, we evaluated biodistribution and whole-body clearance for [¹⁷⁷Lu]Lu-Gemini and, for comparison, our gold-standard monovalent [¹⁷⁷Lu]Lu-S-2-(4-aminobenzyl)-DOTA ([¹⁷⁷Lu]Lu-DOTA-Bn) in naïve (tumor-free) athymic nude mice. For our proof-of-concept system, a 3-step pretargeting approach was performed with an established DOTA-PRIT regimen (anti-GPA33/anti-DOTA IgG-scFv BsAb, a clearing agent, and [¹⁷⁷Lu]Lu-Gemini) in mouse models. Results: Initial in vivo studies showed that [¹⁷⁷Lu]Lu-Gemini behaved similarly to [¹⁷⁷Lu]Lu-DOTA-Bn, with almost identical blood and whole-body clearance kinetics, as well as biodistribution and mouse kidney dosimetry. Pretargeting [¹⁷⁷Lu]Lu-Gemini to GPA33-expressing SW1222 human colorectal xenografts was highly effective, leading to absorbed doses of [¹⁷⁷Lu]Lu-Gemini for blood, tumor, liver, spleen, and kidneys of 3.99, 455, 6.93, 5.36, and 14.0 cGy/MBq, respectively. Tumor–to–normal tissue absorbed-dose ratios (i.e., therapeutic indices [TIs]) for the blood and kidneys were 114 and 33, respectively. In addition, we demonstrate that the use of bivalent [¹⁷⁷Lu]Lu-Gemini in DOTA-PRIT leads to improved TIs and augmented [¹⁷⁷Lu]Lu-Gemini tumor uptake and retention in comparison to monovalent [¹⁷⁷Lu]Lu-DOTA-Bn. Finally, we established efficacy in SW1222 tumor-bearing mice, demonstrating that a single injection of anti-GPA33 DOTA-PRIT with 44 MBq (1.2 mCi) of [¹⁷⁷Lu]Lu-Gemini (estimated tumor-absorbed dose, 200 Gy) induced complete responses in 5 of 5 animals and a histologic cure in 2 of 5 (40%) animals. Moreover, a significant increase in survival compared with nontreated controls was noted (maximum tolerated dose not reached). Conclusion: We have developed a bivalent DOTA-radiohapten, [¹⁷⁷Lu]Lu-Gemini, that showed improved radiopharmacology for DOTA-PRIT application. The use of bivalent [¹⁷⁷Lu]Lu-Gemini in DOTA-PRIT, as opposed to monovalent [¹⁷⁷Lu]Lu-DOTA-Bn, allows curative treatments with considerably less administered ¹⁷⁷Lu activity while still achieving high TIs for both the blood (>100) and the kidneys (>30).

The U.S. Navy began its deep-sea search this week for the remains of an MH-60S Sea Hawk helicopter and the remains of five sailors who died after the aircraft crashed into waters off the San Diego coast on Aug. 31.

Find out how and why your brain divides your day into meaningful chapters.

Ahead of the Food Systems Summit, join the Publications team to find out more about where to find FAO publications, the different formats available, how you can re-use the [...]

Ahead of the Food Systems Summit, join the Publications team to find out more about where to find FAO publications, the different formats available, how you can re-use the [...]

For the first time ever, the Food and Agriculture Organization of the United Nations (FAO) will be hosting two back-to-back conferences looking at the challenges and solutions for sustainable livestock [...]

In this episode, FAO calls for urgent funding to prevent further starvation and suffering in Haiti; FAO’s Director-General underscores that the world should step up efforts and cooperation to tackle [...]

In this episode, FAO welcomed the 'Pact for the Future' in New York, International Food Loss and Waste Day, and an atlas to combat livestock disease.

Your feedback on the First Continental Congress, Douglas MacArthur and England's tangled history

Have you ever wondered why Yellowstone is full of hot springs, bubbling mudpots and geysers like Old Faithful? In this one-minute video, Ask Smithsonian host Eric Schulze explains the supervolcano that lies beneath this national park and answers the life-or-death question: Will it erupt in a fiery inferno anytime soon?

An 18-year-old man charged with attempted murder in a small northern Ontario community made a brief court appearance today by video, and remains in custody. Meanwhile, community members gathered outside the courthouse for a rally.

3D CAD software fuels cool aircraft design innovation, while halving design time and cutting costs

Relies on SolidWorks Simulation Software to Ensure Flight Worthiness, Safety

The world’s largest floating book fair welcomes its five millionth visitor as the tour of Asia comes to a conclusion.

Penn State Schuylkill’s Alpha Epsilon Lambda chapter of Lambda Pi Eta, the national communication honor society, inducted eight new members in a ceremony held at the Michael C. Fryer Conference Center on Oct. 16. Lambda Pi Eta, founded in 1985, recognizes academic excellence in communication students and promotes professional development.

Leaders at DREAM's REAL Kid's New York summer academic and baseball program decided early on to move the program online. To do that, they relied on their core principle: the value of being on a team.

Penn State Fayette, The Eberly Campus is dedicating September to raising awareness about suicide prevention through a series of events and activities. This initiative follows the official proclamation by the Fayette County Commissioners, recognizing September as Suicide Prevention and Awareness Month.

Proptech refers to the use of technology and software to assist the real estate market with its needs.

In response to recent federal U.S. Treasury policy changes, the Delaware State Housing Authority (DSHA) will temporarily pause accepting new applications for the Delaware Housing Assistance Program (DEHAP) at 4:00 p.m. on Friday, September 9. 

Activities include, among others, a wetland walk and campfire, and a program on Colonial Delaware crime and punishment

Events include lectures, tours and Delaware’s 24th Chautauqua tent show.

Wilmington, Del. (September 1, 2023) – The Delaware Division of the Arts’ Mezzanine Gallery presents Bryant “Tee” Bell’s exhibition, “Enlightenment,” running September 1-29, 2023.  Bell is an Emerging 2023 Individual Artist Fellow in the field of visual arts: painting. Guests are invited to attend a Meet-the-Artist Reception on Friday, September 8 from 5:00-7:00 p.m. (Art […]

Literacy Month is intended to recognize the extensive efforts of literacy partners to promote reading as an essential skill and a lifelong pleasure.

Attorney General Jennings joined a multistate coalition of attorneys general announcing a $10 million settlement with payment processor ACI Worldwide over a 2021 testing error that led to the attempted unauthorized withdrawal of $2.3 billion from the accounts of mortgage-holders. This case was investigated and negotiated with the state financial regulators. The state regulators have entered […]

Two men have been found guilty of all charges relating to a January 2022 violent crime spree, marking the final conviction in a massive four-defendant indictment. Walike Parham, 24, and Kyair Keys, 20, could face life in prison for their roles in an eight-day violent crime spree involving four shootings, including one that shattered the […]