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McMaster University Researchers Uncover Potential Treatment for Rare Genetic Disorders

In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases--two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord. After years of investigating the diseases' underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.




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Community Partners Key to Success of Vaccine Clinic Focused on Neurodevelopmental Conditions

Community partnerships led to a specialized clinic delivering COVID and flu shots to individuals with neurodevelopmental conditions like autism at the MIND Institute.




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Lean Hypotheses and Effectual Commitments: An Integrative Framework Delineating the Methods of Science and Entrepreneurship




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When There's No One Else to Blame: The Impact of Coworkers' Perceived Competence and Warmth on the Relations between Ostracism, Shame, and Ingratiation




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The Dismissal of New Female CEOs: A Role Congruity Perspective




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When Private Equity Acquires Firms Expecting Them to Grow

Private equity is more likely to look at public firms for acquisition when the target aggressively manages its earnings to meet analyst expectations, because those firms are often so cut to the bone there's more room to add value with investment.




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Key Executive Appointments Announced at UK HealthCare

University of Kentucky Co-Executive Vice Presidents for Health Affairs Eric N. Monday and Robert S. DiPaola sent the following message to the UK HealthCare community on Nov. 6, 2024: We are very pleased to announce that Chris DeSimone and Tim Slocum have accepted the positions of Executive Chief Medical Officer and Senior Vice President and Chief Operations Officer, respectively.




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Virtue Signaling in the Sharing Economy: The Effect of Airbnb Entrepreneurs' Virtue Language on Airbnb Price Premiums




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How Does Legal Status Inform Immigrant Agency During Encounters of Workplace Incivility?




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Stent em forma de ampulheta poderia aliviar a intensa dor toracica causada pela doenca microvascular

Um estudo da Mayo Clinic sugere que um stent em forma de ampulheta poderia melhorar o fluxo sanguineo e aliviar a dor toracica intensa e recorrente em pessoas com microangiopatia.




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Estent en forma de reloj de arena podria aliviar el intenso dolor en el pecho causado por la enfermedad microvascular

Un estudio de Mayo Clinic sugiere que un estent en forma de reloj de arena podria mejorar el flujo sanguineo y aliviar el dolor toracico intenso y recurrente en personas con microangiopatia.




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Nurses' Extraordinary Experiences During the COVID-19 Pandemic

A new book, Nurses' Extraordinary Experiences During the COVID-19 Pandemic: There was Something in the Air, offers a poignant and firsthand account of the challenges and triumphs faced by nurses during the most devastating pandemic of our generation.




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University of Central Florida's A Team with A Dream secures gold at the DOE's 10th CyberForce Competition(r)

University of Central Florida's A Team with A Dream wins the 2024 CyberForce Competition(r). The mission of the competition is to equip the next generation of cybersecurity professionals with hands-on experience defending critical infrastructure.




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Cedars-Sinai Experts Available for Interviews During American College of Rheumatology Convergence 2024




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NJ Becomes First State to Have Statewide Law Enforcement & Mental Health Alternative Response Program in Nation

ARRIVE Together of Middlesex County, NJ, run by University Behavioral Health Care (UBHC) at Rutgers Health, has expanded its partnerships to include the East Brunswick, South River and Cranbury police departments, making New Jersey the first state in the nation to have a statewide law enforcement and mental health alternative response program.




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Treatment Advances, Predictive Biomarkers Stand to Improve Bladder Cancer Care

Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a New England Journal of Medicine editorial published by Matthew Milowsky, MD, FASCO, a bladder cancer expert at UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.




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NYC's Ride-Hailing Fee Failed to Ease Manhattan Traffic, New NYU Tandon Study Reveals

New York City's 2019 ride-hailing surcharge cut overall taxi and ride-share trips by 11 percent in Manhattan but failed to reduce traffic congestion, a key goal of the policy, according to a new NYU Tandon School of Engineering study published in Transportation Research Part A."While this surcharge differs from the MTA's proposed congestion pricing plan, the study's findings can contribute to the current discourse," said Daniel Vignon, who led the research.




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Linking Data on Genetics, Traits and Environment Gives Crop Breeders a Wider Lens

The interplay between the genetic makeup of crops and the conditions in which they grow is difficult to untangle. A research team led by an Iowa State University professor aims to help breeders analyze the interactions to make crops more resilient and productive.




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Researchers Reveal Why a Key Tuberculosis Drug Works Against Resistant Strains

Rutgers Health study uncovers vulnerabilities in drug-resistant TB, offering hope for improved treatments.




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Vaccine Shows Promise Against Aggressive Breast Cancer

A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine -- known as a neoantigen DNA vaccine -- for breast cancer patients.




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McMaster University Researchers Uncover Potential Treatment for Rare Genetic Disorders

In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases--two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord. After years of investigating the diseases' underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.




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Community Partners Key to Success of Vaccine Clinic Focused on Neurodevelopmental Conditions

Community partnerships led to a specialized clinic delivering COVID and flu shots to individuals with neurodevelopmental conditions like autism at the MIND Institute.




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KRICT Sets New World Record for Large-Area Perovskite Solar Cells, Accelerating Commercialization

KRICT sets a new world record for large-area perovskite solar module efficiency and accelerates commercialization




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Virtue Signaling in the Sharing Economy: The Effect of Airbnb Entrepreneurs' Virtue Language on Airbnb Price Premiums




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How Does Legal Status Inform Immigrant Agency During Encounters of Workplace Incivility?




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Expert Shares Advice on How to Talk Politics with Family, Friends at the Thanksgiving Table

The election is over, but conversations surrounding the outcome are sure to continue for weeks to come. With Thanksgiving right around the corner, knowing how to engage with friends and family members with differing political views may help keep tempers at bay - and relationships intact. Virginia Tech expert Todd Schenk shared his advice for how to keep the peace.




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Expert Available: What to Expect on the Regulatory Front of a Second Trump Presidency

U.S. President-elect Donald Trump has tapped Elon Musk and Vivek Ramaswamy to lead a new commission on cutting government spending and regulation. ...




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Expert Available: Online Hate Intensified Immediately Following U.S. Presidential Election

According to the Global Project Against Hate and Extremism, hateful and violent rhetoric in support of president-elect Donald Trump appeared online on fringe platforms within moments of Trump's... ...




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NJ Becomes First State to Have Statewide Law Enforcement & Mental Health Alternative Response Program in Nation

ARRIVE Together of Middlesex County, NJ, run by University Behavioral Health Care (UBHC) at Rutgers Health, has expanded its partnerships to include the East Brunswick, South River and Cranbury police departments, making New Jersey the first state in the nation to have a statewide law enforcement and mental health alternative response program.




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NYC's Ride-Hailing Fee Failed to Ease Manhattan Traffic, New NYU Tandon Study Reveals

New York City's 2019 ride-hailing surcharge cut overall taxi and ride-share trips by 11 percent in Manhattan but failed to reduce traffic congestion, a key goal of the policy, according to a new NYU Tandon School of Engineering study published in Transportation Research Part A."While this surcharge differs from the MTA's proposed congestion pricing plan, the study's findings can contribute to the current discourse," said Daniel Vignon, who led the research.




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How Taurus and Aquarius Compatibility Can Thrive Despite Differences

Discover Taurus and Aquarius compatibility in love, friendship, and more. Uncover their unique strengths, challenges, and potential for a balanced relationship




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Korean American Dave Min Wins Congressional Seat

[International] :
California State Sen. Dave Min has won a seat in the U.S. House of Representatives, adding one more Korean American voice to the country’s legislature. According to CNN and other media on Wednesday, Min, a Democrat, defeated Republican Scott Baugh and was poised to win the seat for California’s 47th ...

[more...]




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Top Court Upholds Suspended Sentence for Ex-Lawmaker Who Embezzled Donations Meant for Victims of Sex Slavery

[Politics] :
The Supreme Court has upheld a suspended prison term for former Rep. Youn Mee-hyang, who was convicted of embezzling donations to an advocacy group for South Korean victims of sexual slavery during World War II. On Thursday the top court upheld the 18-month sentence, suspended for three years, after ...

[more...]




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China Picks Deputy UN Representative as Ambassador to S. Korea

[International] :
China has named Dai Bing, deputy chief of its permanent mission to the United Nations, as the new ambassador to South Korea. According to diplomatic sources on Thursday, Beijing nominated the UN mission deputy to succeed former Ambassador Xing Haiming, who left the post vacant in July.  Dai’s career ...

[more...]




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Court Begins Review of Pretrial Detention Warrants for Key Figures in Election-Meddling Scandal

[Politics] :
A court review is underway for pretrial detention warrants for four people suspected of involvement in election nomination meddling involving first lady Kim Keon-hee, as well as illegal polling. The Changwon District Court started the warrant hearings Thursday afternoon for power broker Myung Tae-kyun, ...

[more...]




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Gov’t to Take ‘Effective, Phased’ Steps on N. Korean Troop Activity in Russia

[Inter-Korea] :
The government reiterated that it will take “effective and phased” steps, in line with the principles of composure and restraint, in response to the battlefield deployment of North Korean troops in support of Russia in its war against Ukraine. Speaking to local reporters on Thursday, an official at ...

[more...]




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Victims of N. Korean Trash Balloons to Be Eligible for Gov’t Compensation

[Inter-Korea] :
People who suffer damages as a result of North Korea’s trash balloon campaign will eventually be eligible for government compensation. The National Assembly passed an amendment to the Framework Act on Civil Defense during a plenary session Thursday, allowing the government to provide compensation for ...

[more...]




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Finance Minister Vows Active Measures to Curb FX Market Volatility if Necessary

[Economy] :
Finance Minister Choi Sang-mok said Thursday that the government will take “active measures” in the event of excessive volatility in the foreign exchange market, as the South Korean won weakened past the psychological threshold of 14-hundred won against the U.S. dollar. The minister made the “verbal ...

[more...]





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Bonding properties and crystal packing in β-(SeCl4)4 derived from Hirshfeld Atom Refinement

Binary chalcogen halogen EX4 species represent intriguing systems in terms of chemical bonding theories, such as hypervalency and stereoactivity of lone electron pairs. Instead of a simple molecular EX4 structure, selenium tetrachloride forms an ionic pair, Cl3Se+Cl−, that assembles into a tetrameric (SeCl4)4 structure, namely, tetra-μ3-chlorido-dodecachloridotetraselenium. This article describes the charge–density analysis of the tetrameric molecule of β-SeCl4 based on the aspherical model obtained from Hirshfeld Atom Refinement of the tetrameric molecule and of an explicit cluster of 15 tetramers that simulates the crystal packing. Deformation density, electron localization function (ELF) and Quantum Theory of Atoms in Molecules (QTAIM) were used to evaluate the bonding situation, the electron-density distribution around the Se atom and the interaction energy of the tetramer.




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Crystal structure of 1,10-phenanthrolinium violurate violuric acid pentahydrate

The title compound [systematic name: 1,10-phenanthrolinium 6-hydroxy-5-(oxidoimino)-1,3-diazinane-2,4-dione–6-hydroxy-5-(hydroxyimino)-1,3-diazinane-2,4-dione–water (1/1/5)], C12H9N2+·C4H2N3O4−·C4H3N3O4·5H2O, is a co-crystal salt hydrate comprising 1,10-phenanthrolinium cations, violurate anions, free violuric acid as co-former and five water molecules of crystallization per formula unit. The violurate and the violuric acid residues each form distinct N—H...O hydrogen-bonded tapes with a common R22(8) hydrogen-bond motif extending parallel to (103). Solvent water molecules connect the tapes to form a tri-periodic hydrogen-bonded network with channels extending parallel to the a-axis direction, which accommodate the N—H...Owater hydrogen-bonded 1,10-phenanthrolinium cations. Direct N—H...O hydrogen bonds between the 1,10-phenanthrolinium and violurate ions are not encountered.




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4 awesome discoveries you probably didn't hear about this week -- Episode 31

4 awesome discoveries you probably didn't hear about this week -- Episode 31




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Direct Lithium Extraction Co. Sees Big Capacity, Time Improvements

Volt Lithium Corp. (VLT:TSV; VLTLF:US; I2D:FSE) says it has significantly improved the operating capacity of its next-generation Direct Lithium Extraction (DLE) technology for processing oilfield brines in Texas' Delaware Basin. Read why one analyst predicts more steady increases.




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Lithium Exploration Initiative Expands Across Western Greenland

Brunswick Exploration Inc. (BRW:TSX.V) announced an extensive expansion of its lithium exploration holdings in Greenland. Read more about the strategic land acquisitions set to drive future lithium exploration and development across the region.




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Target Price Raised 69% on SMR Developer

This New York-based company has made large strides in building out its nuclear reactor program, noted a Benchmark Co. report.




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Viamericas improves money transfer with domestic cash-to-account options

Viamericas, a licensed money transmitter, has launched its...




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Klarna files for US IPO for a valuation between USD 15 and 20 bln

AI-enabled global payment network Klarna has announced that it...




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Visa Flexible Credential expands to the US and UAE

Multinational payment card services corporation



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NovoPayment obtains USD 20 million investment from Morgan Stanley

Investment funds managed by Morgan Stanley Expansion...




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Physicists demonstrate silicon's energy-harvesting power in study