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ECOT Looms Over Ohio Gubernatorial Candidates' Education Plans

Any discussion in politics of the future of education in Ohio inevitably turns to the Electronic Classroom of Tomorrow.




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Florida Gubernatorial Candidate Vows to Stop Common Core

Republican gubernatorial nominee Ron DeSantis is renewing a political trend that had fallen dormant: calling for the end of the use of the shared standards.




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News24 Business | 200 electric Ubers coming to SA next year, starting in Joburg

Uber will bring 200 BYD electric vehicles onto its platform in South Africa, starting with a pilot in Johannesburg in 2025.




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Kubera: Nagarjuna's Intense Avatar Comes Laced With Mystery In New Poster

Directed by Sekhar Kammula, Kubera has been jointly bankrolled by Puskur Ram Mohan Rao and Suniel Narang




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DPH Observes World Tuberculosis (TB) Day on March 24

The Delaware Division of Public Health (DPH) will join health organizations and advocates around the globe to recognize World Tuberculosis (TB) Day on Sunday, March 24. This day commemorates Dr. Robert Koch’s groundbreaking discovery of Mycobacterium tuberculosis and is used to raise awareness and increase education about the threat of TB. DPH’s Tuberculosis Elimination and […]



  • Delaware Health and Social Services
  • Division of Public Health
  • News
  • Awele Maduka-Ezeh
  • Delaware Division of Public Health
  • DPH
  • Office of Infectious Disease Epidemiology
  • OIDE
  • Tara Jenkins
  • Tuberculosis Elimination and Control Branch

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High risk of tuberculosis in SA children under ten – study




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'Alarming' Rise Seen in Drug-Resistant Tuberculosis

Title: 'Alarming' Rise Seen in Drug-Resistant Tuberculosis
Category: Health News
Created: 8/30/2012 2:05:00 PM
Last Editorial Review: 8/31/2012 12:00:00 AM




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The treatment of latent tuberculosis infection in migrants in primary care versus secondary care

Extract

With a disproportionate burden of tuberculosis (TB) amongst migrants in Europe [1], Burman et al. [2] have highlighted the pressing need for alternative approaches to make TB infection (TBI) screening comprehensive and accessible. Across high-income Organisation for Economic Co-operation and development countries, a median of 52% of TB cases occur in foreign-born individuals, who are at their highest risk of developing TB disease within the first 5 years of migration [3]. Molecular epidemiological studies indicate that the majority of these cases occur as a result of TBI reactivation, often acquired overseas [4]. Within the UK, overseas-born migrants have a 14-fold higher TB incidence than UK-born individuals [5]. The World Health Organization therefore recommends that migrants from countries with a high TB burden may be prioritised for TBI screening [6, 7].




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Accuracy of CAD4TB (Computer-Aided Detection for Tuberculosis) on paediatric chest radiographs

Background

Computer-aided detection (CAD) systems hold promise for improving tuberculosis (TB) detection on digital chest radiographs. However, data on their performance in exclusively paediatric populations are scarce.

Methods

We conducted a retrospective diagnostic accuracy study evaluating the performance of CAD4TBv7 (Computer-Aided Detection for Tuberculosis version 7) using digital chest radiographs from well-characterised cohorts of Gambian children aged <15 years with presumed pulmonary TB. The children were consecutively recruited between 2012 and 2022. We measured CAD4TBv7 performance against a microbiological reference standard (MRS) of confirmed TB, and also performed Bayesian latent class analysis (LCA) to address the inherent limitations of the MRS in children. Diagnostic performance was assessed using the area under the receiver operating characteristic curve (AUROC) and point estimates of sensitivity and specificity.

Results

A total of 724 children were included in the analysis, with confirmed TB in 58 (8%), unconfirmed TB in 145 (20%) and unlikely TB in 521 (72%). Using the MRS, CAD4TBv7 showed an AUROC of 0.70 (95% CI 0.60–0.79), and demonstrated sensitivity and specificity of 19.0% (95% CI 11–31%) and 99.0% (95% CI 98.0–100.0%), respectively. Applying Bayesian LCA with the assumption of conditional independence between tests, sensitivity and specificity estimates for CAD4TBv7 were 42.7% (95% CrI 29.2–57.5%) and 97.9% (95% CrI 96.6–98.8%), respectively. When allowing for conditional dependence between culture and Xpert assay, CAD4TBv7 demonstrated a sensitivity of 50.3% (95% CrI 32.9–70.0%) and specificity of 98.0% (95% CrI 96.7–98.9%).

Conclusion

Although CAD4TBv7 demonstrated high specificity, its suboptimal sensitivity underscores the crucial need for optimisation of CAD4TBv7 for detecting TB in children.




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Treatment of latent tuberculosis infection in migrants in primary care versus secondary care

Background

Control of latent tuberculosis infection (LTBI) is a priority in the World Health Organization strategy to eliminate TB. Many high-income, low TB incidence countries have prioritised LTBI screening and treatment in recent migrants. We tested whether a novel model of care, based entirely within primary care, was effective and safe compared to secondary care.

Methods

This was a pragmatic cluster-randomised, parallel group, superiority trial (ClinicalTrials.gov: NCT03069807) conducted in 34 general practices in London, UK, comparing LTBI treatment in recent migrants in primary care to secondary care. The primary outcome was treatment completion, defined as taking ≥90% of antibiotic doses. Secondary outcomes included treatment acceptance, adherence, adverse effects, patient satisfaction, TB incidence and a cost-effectiveness analysis. Analyses were performed on an intention-to-treat basis.

Results

Between September 2016 and May 2019, 362 recent migrants with LTBI were offered treatment and 276 accepted. Treatment completion was similar in primary and secondary care (82.6% versus 86.0%; adjusted OR (aOR) 0.64, 95% CI 0.31–1.29). There was no difference in drug-induced liver injury between primary and secondary care (0.7% versus 2.3%; aOR 0.29, 95% CI 0.03–2.84). Treatment acceptance was lower in primary care (65.2% (146/224) versus 94.2% (130/138); aOR 0.10, 95% CI 0.03–0.30). The estimated cost per patient completing treatment was lower in primary care, with an incremental saving of GBP 315.27 (95% CI 313.47–317.07).

Conclusions

The treatment of LTBI in recent migrants within primary care does not result in higher rates of treatment completion but is safe and costs less when compared to secondary care.




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The trick to Dragon Age's lore is that the lore is lying, says original "uber-plot" writer David Gaider

Part of the fun of Dragon Age's fantasy is that it's inconsistent - or at least, inconsistent by the standards of fantasy RPGs, which often break down into a million neatly organised and interlocking codex entries. It all rides on who you speak to. The humans believe one thing about the origins and workings of Thedas, the elves another, the qunari something else entirely. These differences are the basis for many factional disagreements and thus, many core series plot developments. According to former lead writer David Gaider, however, there's an "uber-plot" behind it all that may one day be resolved and bring the series to a close, assuming BioWare continue to refer to his original (and closely guarded) narrative documents.

Read more




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Une ancienne boîte St-Hubert des années 70 retrouvée dans l’entretoit d’un chalet près de Stoneham et remise à la famille Martin en échange d'un don de 1000$

Une ancienne boîte de poulet St-Hubert, retrouvée par hasard dans l’entretoit d’un chalet, a été remise à la famille Martin en échange d'un don.




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India Nature Watch - <h1> <font color = blue> Blue mud dauber wasp <h1/p>

Thanks to Sivakumar ji for correcting the ID.

Family: Scoliidae




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New Nasal Spray Could Be a Breakthrough in Treating Brain Tuberculosis

For the first time, scientists have devised an innovative method to deliver tuberculosis (TB) (!--ref1--) medication directly to the brain through the nasal route.




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HIV Antibody Response Raised in Patients With Tuberculosis Disease

medlinkHIV/medlink patients with pulmonary tuberculosis had broader and more potent HIV antibodies compared to those without suspected or documented




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Promising Tuberculosis Therapy for HIV-positive Patients

A promising new therapy for medlinktuberculosis/medlink (TB) has been shown to be compatible with combined antiretroviral therapy (cART), stated research




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Your Favorite YouTubers Can Now Turn Their Videos into Shopping Malls

YouTube has officially launched YouTube Shopping in India, a feature designed to expand revenue opportunities for video creators by integrating e-commerce directly into their content.   Building on the success of similar launches in markets like South Korea and the U.S.,




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Kubera Poster Unveiled: Nagarjuna's Next Big Project Hits Theaters Soon

Nagarjuna's intense new look in 'Kubera' has been revealed, with the film's highly anticipated first glimpse.




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Der Zauberstab der Analogie : Untersuchungen zu den Erscheinungsweisen und Funktionen von Analogien in sprachlichen Sinnbildungsprozessen [Electronic book] / Wilhelm Köller.

Berlin ; Boston : De Gruyter, [2023]




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Nach der Diktatur : Die Aufarbeitung von Gewaltherrschaften [Electronic book] / hrsg. von Peter Hoeres, Hubertus Knabe.

München ; Wien : De Gruyter Oldenbourg, [2023]




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Johannes Rothes Elisabethleben : Aufgrund des Nachlasses von Helmut Lomnitzer [Electronic book] / hrsg. von Annegret Haase, Martin J. Schubert.

Berlin : Akademie Verlag, [2005]




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Ästhetik des Depressiven [Electronic book] / hrsg. von Till Huber, Immanuel Nover.

Berlin ; Boston : De Gruyter, [2023]





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Amidst tubers, roots in a rural set up



  • A J Vinayak

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Ultrasound-assisted ionic liquid-mediated green method for synthesis of 1,3-diphenylpyrazole-based spirooxindolopyrrolizidines, their anti-tubercular activity, molecular docking study and ADME predictions

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4NJ00563E, Paper
Sravanthi Baddepuri, G. Rama Krishna, Jyothi Kumari, Sriram Dharmarajan, Srinivas Basavoju
The aim of the study is to develop the synthesis of a novel series of potent anti-tubercular (anti-TB) activity of 1,3-diphenylpyrazole-based spirooxindolopyrrolizidine derivatives via an efficient green approach achieved by...
The content of this RSS Feed (c) The Royal Society of Chemistry




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After Youtuber's arrest, Kerala govt warns stern legal action against misleading social media content

Kerala Police arrested controversial Youtuber 'Thoppi' who had been accused of making allegedly objectionable remarks and creating a traffic block in Malappuram district





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Should men be allowed into operation theatres when their wives are having a baby? Doctors weigh in after YouTuber’s video sparks controversy

YouTuber Irfan recently posted a video on social media that showed him cutting the umbilical cord of his newborn, in the operation theatre of a private hospital in Chennai; consent of the medical personnel involved to being videoed was another aspect doctors say needs discussion




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AIIMS-Bibinagar to boost tuberculosis care in Telangana with aerial aid

Inaugurated virtually by Prime Minister Narendra Modi, the drone service is part of a series of health projects designed to enhance access to essential services in remote and underserved areas




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Tuberculosis infected 8 million people last year, the most WHO has ever tracked

The World Health Organization says more than 8 million people were diagnosed with tuberculosis last year




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NSA Director of Cybersecurity Anne Neuberger in Conversation with Garrett Graff

Anne Neuberger, Director of Cybersecurity at the National Security Agency, speaks with WIRED's Garrett Graff as part of WIRED25, WIRED's second annual conference in San Francisco.




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IISc Ph.D. student wins award in Berlin for a device that detects drug-resistant tuberculosis

Entire infrastructure could fit into a small briefcase, and it is expected to provide the much-needed breakthrough in the field of TB diagnostics




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Quitting the ‘ola-uber game’

Driving for cab aggregators isn’t appealing any longer to drivers




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Disease Control and Inequality Reduction: Evidence from a Tuberculosis Testing and Vaccination Program [electronic journal].




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Uber liable for GST as e-commerce operator, rules Karnataka AAR

This applies even when Uber only connects drivers and passengers via its app, with drivers receiving payment directly




uber

Armed forces move to scrap mobility contract, Uber says “ready to discuss our data-security practices”

Concerns about data security practices prompt the move




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Boxing competition disrupted by man claiming to be YouTuber in Kerala




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Mid-tier exuberance: Range Rover Velar

Land Rover’s straightforward segmentation puts its mid-tier Velar in the spotlight




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Ceiling prices of 8 common drugs raised by 50%, these medicines treat asthma, tuberculosis, others...

The National Pharmaceutical Pricing Authority (NPPA) has sanctioned the ceiling price hike for 11 formulations by 50 per cent in response to representations from drug makers.




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Rewriting, computation and proof [electronic resource] : essays dedicated to Jean-Pierre Jouannaud on the occasion of his 60th birthday / Hubert Comon-Lundh, Claude Kirchner, Hélène Kirchner (eds.)

Berlin ; New York : Springer, 2007




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Assessing India’s tuberculosis burden: Data

India accounted for 26% of global TB cases and 26% of global TB deaths in 2023




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It’s Maharashtra’s youthful exuberance vs Tamil Nadu’s tactical brilliance




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Mechanistic insights into EGCG's preventive effects on obesity-induced precocious puberty through multi-omics analyses

Food Funct., 2024, 15,11169-11185
DOI: 10.1039/D4FO03844D, Paper
Qiuyun Gu, Qiujv Du, Lina Xia, Xiaoting Lu, Xiaoqing Wan, Ying Shao, Jieyi He, Peiying Wu
Epigallocatechin gallate (EGCG) has demonstrated potential effects on obesity-induced precocious puberty, but the underlying mechanisms remain unclear.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Meet the EduTubers

Teaching and learning have now taken on a new dimension. Talented educators are reaching out to thousands of students through their YouTube channels.




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Meet Former Teacher Who Began Cooking Channel At 52 Years To Fight Loneliness And Is Now India’s Richest YouTuber

With a net worth of Rs 43 crore and 14.5 million subscribers on YouTube, Nisha has built an online empire around her love for home-style Indian cuisine.   




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Ola and Uber: Time for transparency?




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Youtuber murder: Pistols, phones seized from Dalla men

The official said Sukhvinder's brother Satpal possibly transferred Rs 2.50 lakh from Canada to his cousin Jitu Singh alias Jita in Gwalior to facilitate the November 7 killing.




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Data-based methods for materials design and discovery: basic ideas and general methods / Ghanshyam Pilania, Prasanna V. Balachandran, James E. Gubernatis, Turab Lookman

Online Resource




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President Eisgruber issues statement on federal immigration executive order

Princeton President Christopher L. Eisgruber issued a statement to the University community Sunday, Jan. 29, 2017, on the federal immigration executive order.




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Eisgruber, other university presidents ask President Trump to 'rectify or rescind' immigration order

Princeton President Christopher L. Eisgruber and 47 other American college and university presidents today sent a letter to President Trump urging him to "rectify or rescind the recent executive order closing our country's borders to immigrants and others from seven majority-Muslim countries and to refugees from throughout the world." "If left in place," the letters says, "the order threatens both American higher education and the defining principles of our country."