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Tulalip Microsoft's New Social Network ?

With all the talk about Google and their new social network Google Plus, (Or Google+) it looks like there could soon be a new player to what appears to be a rapidly growing social network feud. Recently either by accident or on purpose Microsoft unveiled a new site called Tulalip. Personally I don’t think this was by accident, rather a clever way at generating some buzz..............




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How the Republican Party’s capitulation gave us Donald Trump

Tim Alberta's new book chronicles a decade of GOP recklessness, cowardice and excuses




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CBD News: The President of the Conference of the Parties and Executive Secretary Congratulate Countries that Have Submitted on Time Their Fourth National Reports and Urge all Parties to Meet Their Reporting Obligations Under the Convention




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CBD News: First, I would like to congratulate the Arab Society for Fungal Conservation for declaring 20 February as Egyptian Fungus Day. This initiative truly demonstrates commitment towards conservation of biodiversity and promoting the objectives of the




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SNMMI Leadership Update: To the SNMMI-TS: Congratulations on 50 Years of Dedicated Service to SNMMI and Your Patients




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Du traitement des maladies du coeur par la méthode des Drs Schott, de Nauheim / par le docteur Moeller, médecin praticien à Bruxelles, membre titulaire de l'Académie royale de médecine de Belgique, etc / par la methode des drs

Bruxelles : A. Manceaux, 1893.




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Congratulations to the Winners of the SOLIDWORKS xChallenge 2019!

We are excited to announce the winners of the SOLIDWORKS xChallenge 2019! FIRST® Robotics Competition Teams in the United States were invited to become 3D Creators and 3D Sculptors for the chance to win $10,000. Using xDesign and xShape on the 3DEXPERIENCE Platform, dozens of teams collaborated on the cloud and designed their own personal flying machines. We received 26 entries and a panel of SOLIDWORKS executives and employees judged them all and decided on the top three.

Author information

Sara Zuckerman

Sara Zuckerman is a Content Marketing Specialist in Brand Offer Marketing for SOLIDWORKS and 3DEXPERIENCE Works.

The post Congratulations to the Winners of the SOLIDWORKS xChallenge 2019! appeared first on SOLIDWORKS Education Blog.




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Crisis Group Congratulates the Tunisian National Dialogue Quartet

The International Crisis Group congratulates the members of the Tunisian National Dialogue Quartet as this year’s recipient of the Nobel Peace Prize. It is an apt recognition of its achievement in allowing the spirit of inclusion and compromise to triumph over the polarisation and violence that has been all too prevalent in the region, and of the central role civil society can play at moments of crisis.




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Ankara congratulates EU on Europe Day

The president of Turkey on May 9 marked the annual Europe Day, saying the EU would come out of its current pandemic-induced crisis stronger with the right and timely steps.




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Millions of hairy tarantula skins could be used to mop up oil spills

The dense, bristly hairs on the skins shed by tarantulas when they moult are naturally efficient sponges and could be used to soak up ocean oil spills




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Ear Infections: 'Breakthrough' Ear Tube Surgery Tula Approved

Title: Ear Infections: 'Breakthrough' Ear Tube Surgery Tula Approved
Category: Health News
Created: 11/26/2019 12:00:00 AM
Last Editorial Review: 11/27/2019 12:00:00 AM




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MtSSPdb: The Medicago truncatula Small Secreted Peptide Database

A growing number of small secreted peptides (SSPs) in plants are recognized as important regulatory molecules with roles in processes such as growth, development, reproduction, stress tolerance, and pathogen defense. Recent discoveries further implicate SSPs in regulating root nodule development, which is of particular significance for legumes. SSP-coding genes are frequently overlooked, because genome annotation pipelines generally ignore small open reading frames, which are those most likely to encode SSPs. Also, SSP-coding small open reading frames are often expressed at low levels or only under specific conditions, and thus are underrepresented in non-tissue-targeted or non-condition-optimized RNA-sequencing projects. We previously identified 4,439 SSP-encoding genes in the model legume Medicago truncatula. To support systematic characterization and annotation of these putative SSP-encoding genes, we developed the M. truncatula Small Secreted Peptide Database (MtSSPdb; https://mtsspdb.noble.org/). MtSSPdb currently hosts (1) a compendium of M. truncatula SSP candidates with putative function and family annotations; (2) a large-scale M. truncatula RNA-sequencing-based gene expression atlas integrated with various analytical tools, including differential expression, coexpression, and pathway enrichment analyses; (3) an online plant SSP prediction tool capable of analyzing protein sequences at the genome scale using the same protocol as for the identification of SSP genes; and (4) information about a library of synthetic peptides and root and nodule phenotyping data from synthetic peptide screens in planta. These datasets and analytical tools make MtSSPdb a unique and valuable resource for the plant research community. MtSSPdb also has the potential to become the most complete database of SSPs in plants.




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Atorvastatin Reduces In Vivo Fibrin Deposition and Macrophage Accumulation, and Improves Primary Patency Duration and Maturation of Murine Arteriovenous Fistula

Background

Arteriovenous fistulas placed surgically for dialysis vascular access have a high primary failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis. No clinically established pharmacologic or perisurgical therapies currently address this unmet need. Statins’ induction of multiple anti-inflammatory and antithrombotic effects suggests that these drugs might reduce arteriovenous fistula failure. Yet, the in vivo physiologic and molecular effects of statins on fistula patency and maturation remain poorly understood.

Methods

We randomized 108 C57Bl/6J mice to receive daily atorvastatin 1.14 mg/kg or PBS (control) starting 7 days before end-to-side carotid artery–jugular vein fistula creation and for up to 42 days after fistula creation. We then assessed longitudinally the effects of statin therapy on primary murine fistula patency and maturation. We concomitantly analyzed the in vivo arteriovenous fistula thrombogenic and inflammatory macrophage response to statin therapy, using the fibrin-targeted, near-infrared fluorescence molecular imaging agent FTP11-CyAm7 and dextranated, macrophage-avid nanoparticles CLIO-VT680.

Results

In vivo molecular-structural imaging demonstrated that atorvastatin significantly reduced fibrin deposition at day 7 and macrophage accumulation at days 7 and 14, findings supported by histopathologic and gene-expression analyses. Structurally, atorvastatin promoted favorable venous limb outward remodeling, preserved arteriovenous fistula blood flow, and prolonged primary arteriovenous fistula patency through day 42 (P<0.05 versus control for all measures).

Conclusions

These findings provide new in vivo evidence that statins improve experimental arteriovenous fistula patency and maturation, indicating that additional clinical evaluation of statin therapy in patients on dialysis undergoing arteriovenous fistula placement is warranted.




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Facial Nerve Arterial Arcade Supply in Dural Arteriovenous Fistulas: Anatomy and Treatment Strategies [INTERVENTIONAL]

BACKGROUND AND PURPOSE:

Endovascular treatment of petrous dural AVFs may carry a risk of iatrogenic facial nerve palsy if the facial nerve arterial arcade, an anastomotic arterial arch that supplies the geniculate ganglion, is not respected or recognized. Our purpose was to demonstrate that the use of a treatment strategy algorithm incorporating detailed angiographic anatomic assessment allows identification of the facial nerve arterial arcade and therefore safe endovascular treatment.

MATERIALS AND METHODS:

This was a retrospective cohort study of consecutive petrous dural AVF cases managed at Toronto Western Hospital between 2006 and 2018. Our standard of care consists of detailed angiographic assessment followed by multidisciplinary discussion on management. Arterial supply, primary and secondary treatments undertaken, angiographic outcomes, and clinical outcomes were assessed by 2 independent fellowship-trained interventional neuroradiologists.

RESULTS:

Fifteen patients had 15 fistulas localized over the petrous temporal bone. Fistulas in all 15 patients had direct cortical venous drainage and received at least partial supply from the facial nerve arterial arcade. Following multidisciplinary evaluation, treatment was performed by endovascular embolization in 8 patients (53%) and microsurgical disconnection in 7 patients (47%). All patients had long-term angiographic cure, and none developed iatrogenic facial nerve palsy.

CONCLUSIONS:

By means of our treatment strategy based on detailed angiographic assessment and multidisciplinary discussion, approximately half of our patients with petrous AVFs were cured by endovascular treatment, half were cured by an operation, and all had preserved facial nerve function.




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Celebrities join Earl of Wessex to send &apos;virtual congratulations&apos; to Duke of Edinburgh award winners

Follow our live coronavirus updates HERE Coronavirus: The symptoms




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Keir Starmer and Matt Hancock lead congratulations to Boris Johnson and Carrie Symonds as they welcome baby boy

Labour leader Keir Starmer and Health Secretary Matt Hancock have led the messages of congratulations to Boris Johnson and Carrie Symond's for the birth of their first child.




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Queen congratulates Boris Johnson and Carrie Symonds on birth of baby boy

The Queen has congratulated Boris Johnson and Carrie Symonds on the birth of their son , Buckingham Palace has said.




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Congratulations! Tony Rock Welcomes His First Child



The beautiful baby boy is the comedian’s first child.




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Attorney General Eric Holder Speaks at Tulane University Law School

"Today, by participating in this lecture series, we have a unique and important opportunity to think about this 'sacred covenant,' to consider our responsibilities in upholding it, and – of course – to recommit ourselves to the work that distinguished the lives and legacies of George Dreyfous and Mathilde Schwab Dreyfous," said Attorney General Holder




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Kim Jong Un congratulates Xi on coronavirus handling




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Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo




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Schumacher congratulates Vettel on title

Michael Schumacher congratulated close friend Sebastian Vettel on winning his first drivers' title after an Abu Dhabi Grand Prix that saw him walk away from a frightening collision with Tonio Liuzzi that could have ended in disaster




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Pakistan’s dangerous capitulation to the religious right on the coronavirus

Perform your ablutions at home. Bring your own prayer mats, place them six feet apart. Wear masks. Use the provided hand sanitizer. No handshakes or hugs allowed. No talking in the mosque. No one over 50 years old can enter. No children allowed. These guidelines are part of a list of 20 standard operating procedures that Pakistan’s…

       




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Pakistan’s dangerous capitulation to the religious right on the coronavirus

Perform your ablutions at home. Bring your own prayer mats, place them six feet apart. Wear masks. Use the provided hand sanitizer. No handshakes or hugs allowed. No talking in the mosque. No one over 50 years old can enter. No children allowed. These guidelines are part of a list of 20 standard operating procedures that Pakistan’s…

       




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Pakistan’s dangerous capitulation to the religious right on the coronavirus

Perform your ablutions at home. Bring your own prayer mats, place them six feet apart. Wear masks. Use the provided hand sanitizer. No handshakes or hugs allowed. No talking in the mosque. No one over 50 years old can enter. No children allowed. These guidelines are part of a list of 20 standard operating procedures that Pakistan’s…

       




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Photo: Fancy tarantula shows off his frippery

Our photo of the day comes from the magical rainforest of Ecuador.




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Warm autumn weather brings out troops of amorous tarantulas

An extended mating season is bringing California's tarantulas out in droves; here's a reminder to go easy on the gentle giants.






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Rhian Brewster of England is congratulated by FIFA President, Gianni Infantino

KOLKATA, INDIA - OCTOBER 28: Rhian Brewster of England is congratulated by FIFA President, Gianni Infantino after the FIFA U-17 World Cup India 2017 Final match between England and Spain at Vivekananda Yuba Bharati Krirangan on October 28, 2017 in Kolkata, India. (Photo by Tom Dulat - FIFA/FIFA via Getty Images)




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Goalkeeper Nicolas Sarmiento #1 of Argentina is congratulated by fellow keeper Guido Mosenson

BUCARAMANGA, COLOMBIA - SEPTEMBER 12: Goalkeeper Nicolas Sarmiento #1 of Argentina is congratulated by fellow keeper Guido Mosenson after their 1-0 Group E match win against Kazakhstan in the 2016 FIFA Futsal World Cup on September 12, 2016 in Bucaramanga, Colombia. (Photo by Victor Decolongon - FIFA/FIFA via Getty Images)




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Damian Stazzone of Argentina is congratulated on scoring

CALI, COLOMBIA - SEPTEMBER 28: Damian Stazzone of Argentina is congratulated on scoring during the FIFA Futsal World Cup Semi Final match between Argentina and Portugal at the Coliseo el Pueblo Stadium on September 28, 2016 in Cali, Colombia. (Photo by Ian MacNicol - FIFA/FIFA via Getty Images)




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Dwayne Johnson congratulates his teacher on her retirement with surprise video message

Actor Dwayne Johnson just made his teacher's dream come true! The actor sent out a congratulatory message to Carol Propst, an English teacher at Virginia High School, who was retiring after working for 39 years as a teacher. One of her colleagues reached out to Johnson on Twitter and the actor obliged with a video message.

"Today I received the ultimate retirement send-off: a personalized message from Dwayne @TheRock Johnson! Thanks to all my beloved students and colleagues. BVPS, YOU ROCK! #propstrocks," Propst shared on Twitter.

Dwayne was heard saying, "Hey Carole, Dwayne Johnson here. I wanted to take a moment to say congratulations. Congratulations, Carole, for your retirement from Virginia High School after 39 amazing, incredible years. Wow!"

"Carol. Congratulations! I am so happy for you, and I am so proud of you. And, being that this is teacher appreciation week, on behalf of all parents, Carole I say thank you. Thank you and thank all of your fellow teachers for your wisdom, for your love, for your care, for your discipline — which I needed a lot if you were my teacher. But thank you so much for educating and for caring for our kids," he said.

Dwayne Johnson also sent a gift package to her which included a tequila brand as he said that they would share it one day together.

Seeing her reaction, he responded on Twitter by saying, "Awww I love seeing this. Her reaction is just beautiful. Things like this are the best part of fame."

ALSO READ: Dwayne Johnson and Emily Blunt to reunite for movie adaptation of Ball and Chain




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OECD’s Gurría congratulates President Obama on his re-election victory

In a letter to President Obama, Secretary-General Angel Gurría acknowledged that Americans demonstrated their recognition of the President's many achievements during his first four years in the White House.




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OECD's Gurria congratulates President Obama on taking action to address the unsustainable situation of undocumented immigrants

On the occasion of the OECD High Level Policy Forum on Migration taking place on December 1 and 2 2014, Secretary General Angel Gurria congratulates President Obama on taking action to address the unsustainable situation of undocumented immigrants.




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Angel Gurría congratulates new Indonesian President for cutting fuel subsidies

Angel Gurría, Secretary-General of the OECD congratulated the newly elected President of Indonesia, Joko Widodo, for taking a bold first step in his economic reform agenda by substantially cutting fuel subsidies.




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Angel Gurría congratulates new Indonesian President for cutting fuel subsidies

Angel Gurría, Secretary-General of the OECD congratulated the newly elected President of Indonesia, Joko Widodo, for taking a bold first step in his economic reform agenda by substantially cutting fuel subsidies.




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Harry Maguire, Andre Ward and Ian Wright congratulate Anthony Joshua victory's over Andy Ruiz Jr

Manchester United defender Harry Maguire, former world champion Andre Ward and New Zealand rugby league star Sonny Bill Williams were among the sport stars to hail Anthony Joshua.




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Stars congratulate Anna Heinrich and Tim Robards on baby news

The original Bachelor couple surprised fans on Saturday when they announced they're expecting their first child together.




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Liam Payne congratulates Zayn Malik and Gigi Hadid on their baby news

The singer, 26, took to Instagram Live to send his well wishes to the couple, who are reportedly expecting a girl in September 2020.




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PIERS MORGAN: I congratulated David Schwimmer at an Oscars party... only to find out it wasn't him!

The Good Morning Britain host described the moment he congratulated Dylan McDermott over a reported one-off special of Friends after mistaking him for David Schwimmer.




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Ryan Seacrest congratulates ex Julianne Hough on wedding

They dated from April 2010 to March 2013 before splitting up because of their busy work schedules. The 42-year-old congratulated his ex on her nuptials on ABC's Live! With Kelly And Ryan on Monday morning.




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Cardi B leads the charge of celebrities congratulating Katy Perry on pregnancy with Orlando Bloom

After Katy Perry announced she was expecting her first child with fiance Orlando Bloom, the singer was congratulated by many celebrity fans.




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Liam Payne congratulates Harry Styles for topping the US Billboard charts

Liam Payne has congratulated Harry Styles on his amazing chart success.




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1D fans urge the band to congratulate Zayn Malik on his baby news

The wonderment comes on the back of years of rumoured fractions between Niall Horan, Liam Payne, Harry Styles and Louis Tomlinson and Zayn,




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Love Island winner Paige Turley reveals ex-boyfriend Lewis Capaldi congratulated her

Old flame Lewis, with whom she remains on good terms, was one of the first people to congratulate her on the triumph following her return from South Africa.




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Kobe Bryant congratulated Lebron James in his last tweet

The legendary basketball player took to social media hours before his death to celebrate Lebron James surpassing him to earn the No. 2 All-Time Top Scorer title.




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Barack and Michelle Obama congratulate their own production company after American Factory Oscar win

American Factory, about the decline of manufacturing jobs in the industrial Midwest, picked up the golden statue for best feature-length documentary at the Oscars on Sunday night.




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Brad Pitt's exes get friendly as Gwyneth Paltrow congratulates Jennifer Aniston on SAG Award win 

Gwyneth Paltrow congratulated Aniston on her SAG win in an Instagram comment, Monday. The former Friends actress won a SAG award for her role in The Morning Show.




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Jennifer Aniston congratulated her ex-husband Brad Pitt during another awards season run-in

The actress, 50, congratulated her ex on his win while attending Guy Oseary's annual Oscars party, though this interaction lacked the same flirty vibe as the last one.