DSSP stands as a foundational tool in the domain of protein secondary structure prediction, yet it encounters notable challenges in accurately annotating irregular structures, such as β-turns and γ-turns, which constitute approximately 25%-30% and 10%-15% of protein turns, respectively. This limitation arises from DSSP's reliance on hydrogen-bond analysis, resulting in annotation gaps and reduced consensus on irregular structures. Alternatively, PROMOTIF excels at identifying these irregular structure annotations using phi-psi information. Despite their complementary strengths, previous methodologies utilised DSSP and PROMOTIF separately, leading to disparate prediction methods for protein secondary structures, hampering comprehensive structure analysis crucial for drug development. In this work, we bridge this gap using an annotation fusion approach, combining DSSP structures with beta, and gamma turns. We introduce IRNN-SS, a model employing deep inception and bidirectional gated recurrent neural networks, achieving 77.4% prediction accuracy on benchmark datasets, outpacing current models.

Personalization is one of the most expected features in the current educational systems. User modeling is supposed to be the first stage of this process, which may incorporate learning style as an important part of the model. Learning style, which is a non-stable characteristic in the case of children, differentiates students in learning preferences. This paper identifies a new hybrid method to initiate and update the information of children’s learning style in an educational system. At the start-up phase, children’s learning style information is gathered through the modified Murphy-Meisgeier Type Indicator for Children (MMTIC) questionnaire, which is based on the well-known Myers-Briggs Type Indicator (MBTI). This primary information will be tuned by tracking children’s behaviors during the learning process. Analytical data mining helped us to cluster these behaviors and find their patterns. The proposed method was applied on 81 fourth grade children in elementary school. Delivering results suggest that this method provides a good precision in recognizing children learning style and may be an appropriate solution for non-stability problems in their preferences.

Aim/Purpose: Students face many challenges improving their soft skills such as critical thinking. This paper offers one possible solution to this problem. Background: This paper considers one method of enhancing critical thinking through a problem-solving game called the Coffee Shop. Problem-solving is a key component to critical thinking, and game-playing is one method of enhancing this through an interactive teaching method. Methodology: Three classes of Vietnamese high school students engaged in the Coffee Shop game. The method seeks outcome measurements through the use of analysis of multiple surveys to assess and interpret if critical thinking may have been improved. Contribution: The study may help to understand the importance of problem-solving in the context of an entrepreneurial setting and add to the variation of methods used to deliver the lesson to students in the classroom. Findings: The findings show that practicing problem-solving scenarios with a focus on critical thinking in a time limited setting results in a measured improvement of this skill. Recommendations for Practitioners: The findings suggest that educators could use games more as tools for problem-solving to contribute to their students’ learning outcomes around developing critical thinking. Recommendation for Researchers: More research could be devoted to developing problem-solving and critical thinking skills through game-play models. Impact on Society: Improved critical thinking skills in individuals could make a greater contribution to society. Future Research A comparative study between different high school grades and genders as well as between different countries or cultures.

For advocates of universal gun rights, this debate represents a fundamental question about the nature of the Second Amendment: is it an American right or a human right?

Soaring vegetable prices undermine expectations for a dovish approach in the upcoming monetary policy meeting

In understanding and improving the CAPA system as a whole, this book reflects the importance of the investigation/root cause analysis stage as the necessary step of any effective corrective and preventive action system

In what has been a long period of relative low activity, FDA’s OPDP has taken the opportunity to remind us that low enforcement does not mean no enforcement when it comes to promotional speech by pharmaceutical companies. This past June … Continue reading →

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People ride on motorbikes amid smog on a road in Multan, Pakistan November 12, 2024. — ReutersPunjab chokes on toxic smog despite mitigation effortsMultan records AQI of 396 this morning on IQ Air's live rankings. Man killed, three injured road accident due to low...

Second quarter and first half 2018 results

England great Wayne Rooney was fired as the manager of second-tier club Birmingham on Tuesday after 15 games.

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Alexei Popyrin upset fourth-seeded Daniil Medvedev 6-4, 2-6, 7-6 (4) in the second round of the Paris Masters on Wednesday in a tense match with many ups and downs.

Donald Trump's election win is clouding the outlook for mortgage rates even before he gets back to the White House.

We visit Baltimore Clayworks, where artist Sam Wallace teaches a pottery technique he learned as a kid in Jamaica. We talk with the crew at The Mount Washington Tavern about romance, oyster shucking, and a major fire that put the place out of business for a year. And we drop in at The Village Vet, where the staff cares for ailing animals and the worried humans that come along with them.

Amazon is bringing back the video game adaptation for another year after one of Prime Video's biggest premieres.

The post Fallout TV Series Gets A Second Season first appeared on SciFi Stream.

Care about biodiversity protection and science-policy dialogue? The second BESAFE stakeholder workshop might be just the thing for you.

The BESAFE project invites all interested policy makers, NGO representatives, decision makers and people, who argue ('lobby') for biodiversity protection to take part in its second stakeholder workshop, focusing the results from the project case studies and the best ways to make them useful through a stakeholder focused web-based tool.

The workshop will be held on 13 and 14 May 2004 at the Park Inn Brussels Midi, Brussels, Belgium. To register and participate is easy just follow this link, which will take you to an easy to follow and use registration page.

On the afternoon of 13 May BESAFE will present the results of the project’s case studies and then their use and implications will be discussed with stakeholders. The morning of 14 May is reserved for a learning workshop on the best ways to unlock and present project results. As committed stakeholder involvement is crucial to BESAFE’s success, we hope that you will be able to join us in Brussels!

In a nutshell, BESAFE investigates the effectiveness of different types of arguments in convincing policy makers to take action for biodiversity protection in a variety of circumstances. The project has two specific focus areas: the interactions of environmental protection policies between governance scales, and the contribution that ecosystem services BESAFE is committed to produce practically usable results and to make them available and easily accessible through a web-based tool. This is a goal we can clearly only achieve through input and feedback from stakeholders. BESAFE is therefore set up as an interactive project in which we inform and consult those on a regular basis.

Deadline for registration is the 1st of April 2014, but registration will be closed earlier when our limit of 25 stakeholders is reached. Due to this limited capacity, registration is subject to approval.

The second EU BON Roundtable took place on 27 November 2014 at the Museum für Naturkunde in Berlin. The workshop was dedicated to explore ways in which EU BON can support citizen science (CS) activities. Many partners and interested stakeholders participated, coming from different European research institutions, Natural History Museums, SMEs or representatives from European Institutions like European Commission (DG Research & Innovation and the Joint Research Centre) or the European Environmental Agency and EU-funded Citizen Observatories projects. On secondment to the Earth Observation Sector at DG Research and Innovation, European Commission, Jose-Miguel Rubio-Iglesias showed the possibilities of Citizen Science as one option to improve the science-society bridge. In the following interview he gives an overview of the topic covered and his participation at the round table.

Jose-Miguel Rubio-Iglesias gave a talk on improving the science-society-policy bridge by Citizen Science

Jose-Miguel Rubio-Iglesias, Policy Officer (Spanish National Centre for Geographic Information, on secondment to the European Commission)

Q: Where do you see the place of citizen science in the future of European research and innovation efforts?

A: I see a brilliant future of Citizen Science as a driver for research and innovation activities, especially in its shape of "Citizens' Observatories". The vertiginous increase in the use of mobile technologies, with a pervasive Internet accessible to everyone and social media usage at its peak, offers a world of opportunities for research and innovation in the domain of environmental monitoring technologies where citizens have a key role to play. Citizen science can also foster advancement in social innovation as these are normally collective actions carried out by citizens, sometimes in partnership with NGOs, researchers and public organisations, which are bringing benefits for the whole society. Furthermore, the European Union's Framework Programme for Research and Innovation, Horizon 2020, is already offering a framework to mainstream public engagement in science and research, from programming to implementation and evaluation, being citizen science a one of the key instruments to realise this objective. Data and information gathering, results interpretation and co-creation are examples of activities in which citizens can be involved, leading to different kinds of innovation, including social innovation.

Q: What are the success factors for citizen science? What are the challenges for Citizen Science on a European scale?

A: In my opinion there is no magic formula to achieve success in a citizen science activity, nor any plug-and-play solution. There are many variables that have to be considered, such as the thematic, spatial or temporal scope of the activity. But a common element that seems to be an ingredient for success is to plan carefully not only the process of engagement but the feedback mechanisms, so citizens realise their actions and the outcomes of what they have done are really being useful. Working on creating a strong perception of ownership is always a success factor on a voluntary initiative.

I see a number of challenges for Citizen Science at a European scale, especially, the need for a better coordination of the local and regional activities. This can avoid duplication of initiatives, foster best practices across activities and help position better citizen science vis-à-vis the EU and national and local governments, so citizen science can be higher up on their agendas. In this sense, I think the role of associations such as ECSA (European Citizen Science  Association) is key in achieving this coordination.

Q: How can EU projects on biodiversity information like EU BON facilitate the process?

A: EU BON, like other EU projects which have biodiversity information as a focus, has an important role to make visible the knowledge treasured by citizen science groups. The European Biodiversity Portal, one of the EU BON main achievements, is a fantastic opportunity to open up the wealth of biodiversity data which has been collected by citizens throughout Europe, making it available for a better informed decision making in those areas in which biodiversity has a role.

Q: Where do you see the place of large European Earth observation projects such as EU BON in the global context?

A: The biodiversity information system resulting from EU BON is one of the main European contributions to GEO BON (GEO Biodiversity Observation Network), which is a flagship initiative of GEO (Group on Earth Observation). GEO BON is joining forces at international level to coordinate the activities relating to the Societal Benefit Area on Biodiversity of the Global Earth Observation System of Systems (GEOSS). Its main goals are to organize and improve terrestrial, freshwater and marine biodiversity observations globally and make their biodiversity data, information and forecasts more readily accessible to policymakers, managers, experts and other users. As EU BON is creating a stable and open-access platform for sharing biodiversity tools and data, taking stock of existing components such as LifeWatch or GBIF, this is clearly a step forward towards the fulfilment of the objectives of GEO BON.

At global level, EU BON and GEOBON are strategically positioned to contribute to delivery of data for the UN Convention on Biological Diversity (CBD) and the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES).

Finally, together with EU BON, other large EU Earth Observation projects, such as SIGMA or Earth2Observe, are also providing an important contribution at global level to GEO, in this case to the GEO Societal Benefit Areas of Agriculture (GEO-GLAM) and Water respectively. 

NOTE: The views expressed in this interview are only of the speaker and do not necessarily reflect the official opinion of the European Commission. 

The second WP6 and 7 workshop was organised by CNRS and took place from 16 to 18 of February in Aix-en-Provence, France. During this meeting, partners brainstormed on possible cross work package papers, products and tasks. Partner’s enthusiasm for the ongoing work and possible impact of EU BON outputs fuelled energetic discussions.

Participants at the workshop. Credit: Florian Wetzel

Topics on the agenda include:

The possibilities of visualisations like Aquamaps and Fishbase to provide information for Marine policy targets or for capacity building on marine biodiversity information. We were very happy to have Sandrine Vaz from IFREMER, Montpellier joining us as an expert on marine data and its policy context.

For the EU BON business plan, the next steps were defined for its development, part of which Pan Xingliang will explore in his masters project. One of the steps will include a strategy meeting with other initiatives and European projects that face the same challenge of ensuring life of their products and networks of knowledge after the project end date.

The objective of the third stakeholder round table was further defined based on lessons learned from previous stakeholder round tables and identifying the information needs from the data portal for EU BON from our EU BON test case study regions.

The second session of the IPBES plenary (IPBES-2) is now assigned to be held in Antalya, Turkey from 9 to 14 December 2013, following the decision of the IPBES Bureau.

As part of the current intersessional process, various draft documents prepared by the Bureau and Multidisciplinary Expert Panel will be available online for review at: www.ipbes.net/intersessional-process. These includes the draft IPBES work programme, stakeholder engagement strategy, guidance on the development of strategic partnerships, and procedures for the preparation of IPBES deliverables. In addition, various regional consultations in preparation for IPBES-2 are also under preparation. Further details can be found at www.ipbes.net/related-events.

The deadline for registration is August 19th, and it should be noted that it will not be possible for any non-government observers who were not present at IPBES-1 to register to participate in IPBES-2 after this date.

Details of the online registration process can be found at www.ipbes.net/plenary/registration-ipbes-2 

The second EU BON WP6 & 7 Workshop will take place from 16 to18 Feb 2015  in Aix-en-Provence, France.

The objective of the workshop is to further develop on cross WP and task interactions and to define outputs. 

Hernández, who hit 33 homers to earn an All-Star nod, helped the Dodgers win the World Series in 2024.

The post Red Sox reportedly interested in Teoscar Hernández for a second straight offseason appeared first on Boston.com.

"Every time you hear a piano note, that's another mass shooting." A new way to hear the stark numbers on gun violence.

Also: Adam Lankford, a criminology professor, turns to data to explain why the US has more mass shootings than any other country; Susan Cruz, a Salvadoran-American, remembers holding a gun at the age of six; two sisters with different opinions on guns go to a shooting range; we learn about the origins of the Second Amendment; plus we hear from faith leaders all over the US.

(Image: Visitors view gun displays at a National Rifle Association outdoor sports trade show on February 10, 2017 in Harrisburg, Pennsylvania. Credit: Dominick Reuter/Getty Images)

Approximately every 30 seconds, a United States citizen of Latin American descent, reaches the voting age of 18. This year, 32 million Latinos are projected to be eligible to vote. Latinos are one of the largest demographic groups in the US. We’ll learn about the history of the ‘Latino vote’ in the US, we’ll meet young Latino voters, and we’ll look into how both major US political parties are trying to gain young Latino support in the lead-up to the election.

(From left, Kathleen Hilibish, 68, and Judi Longacre, 79, volunteer at the voter registration booth at the Perry Township Oktoberfest at Hartwick Park in Canton, Ohio. Credit: Dustin Franz/Getty Images)

Standup comic and actor Bill Burr will host for the second time with Mk.gee as musical guest.

The post ‘Saturday Night Live’ to take on a second Trump term after focusing on Harris appeared first on Boston.com.

Here are the top five MLB second basemen set to become free agents this winter.

A team of Cal Poly architectural engineering (ARCE) students placed second in the Earthquake Engineering Research Institute (EERI) Seismic Design Competition (SDC) in early March in San Diego.

The youth cancer charity's report drew praise from around the sector last year, but it left it with a challenge: how to make it even better

The Prime Minister and the Labour Party leader all got involved in the volunteering event over the weekend

Washington – The Environmental Protection Agency once again has extended the comment period for a proposed rule that would create stronger standards for workers who handle “restricted use” pesticides.

Washington – The second of two public meetings to discuss how OSHA can “reshape” its Voluntary Protection Programs is scheduled for Aug. 28 in New Orleans.

Boston – Despite an overall drop in secondhand smoke exposure in the workplace, workers in industries such as installation and repair, construction, and transportation remain at high risk, concludes a study from the Massachusetts Department of Public Health.

Washington — The Environmental Protection Agency is seeking comment on a draft of Part 2 of a final risk evaluation that concludes asbestos – a known human carcinogen – presents an unreasonable health risk to workers under certain conditions.

Washington — The Environmental Protection Agency has announced the availability of the final scope of Part 2 of the final risk evaluation to be conducted for asbestos.

Washington — New commercial passenger aircraft must have a secondary flight deck barrier to protect the cockpit from “unauthorized intrusion” under a Federal Aviation Administration final rule announced June 14.

State College, PA — The threats of high heat and wildfires are expected to persist well into autumn, AccuWeather says – meaning workers could be at risk.

Washington — The U.S. Department of Agriculture says it’s extending a trial of faster line speeds at select pork-processing facilities so it can design a study to assess worker safety.

Children's Geographies; 06/01/2021
(AN 151284196); ISSN: 14733285
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Children's Geographies; 08/01/2021
(AN 152310089); ISSN: 14733285
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Children's Geographies; 08/01/2023
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January 25, 2013

President Obama officially began his second term of office on January 20th. In his inaugural address to the nation the following day, his focus was on the strengths and promises of America. In this Basic Black conversation, we explore the challenges, the goals, and the demands for the second Obama administration.

Our panel this week:
- Callie Crossley, host and moderator, Boston Public Radio, WGBH
- Kim McLarin, assistant professor of writing, literature and publishing, Emerson College
- Phillip Martin, senior reporter, 89.7 WGBH Radio
- Peniel Joseph, professor of history, Tufts University
- Robert Fortes, Republican strategist and political consultant




Photo: Supreme Court Chief Justice John Roberts administers the oath of office to President Barack Obama during the inaugural swearing-in ceremony at the U.S. Capitol in Washington, D.C., Jan. 21, 2013. (Official White House Photo by Sonya N. Hebert)

Tickets for the May 3 show go on sale at 10 a.m. Thursday.

Ohio State prepares for its second game this week against Tulsa.

[Domestic] :
Memorial events are taking place across the country to honor the victims of the Itaewon crowd crush on Tuesday, the second anniversary of the tragedy.  Earlier in the day, a memorial event at the National Assembly brought together survivors, members of the bereaved families, the National Assembly ...

[more...]