Escuche el programa de este jueves 7 de noviembre. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que desde hace 31 años acompaña a sus oyentes en su regreso casa.

En Caracol Radio estuvo el secretario de Salud de Cali conversando sobre las medidas que realiza la Alcaldía ante el pico de casos de dengue

Varias denuncias demostrarían que hay presiones sobre algunos miembros del Consejo Superior Universitario, organismo que se encargará de la elección del nuevo rector.

A través de un comunicado, solicitaron su liquidación a la Superintendencia al argumentar que no son sostenibles en materia económica y financiera

En 6AM Hoy por Hoy de Caracol Radio estuvo Lady Catherine Piza, secretaria de Agricultura de Boyacá, para hablar un poco sobre la temporada de lluvias que se vive en el departamento y dio algunas recomendaciones y preparaciones para esto.

El secretario de Seguridad Bogotá, César Restrepo recomendó en 6AM a los ciudadanos tomar rutas alternas, porque las inundaciones continúan.

El secretario de Seguridad Bogotá, César Restrepo recomendó en 6AM a los ciudadanos tomar rutas alternas porque las inundaciones continúan, mientras que el concejal Samir Abisambra alertó por nuevas emergencias.

POLITICO’s California Playbook discusses the latest in state politics. How Kamala Harris’s upbringing and earlier campaigns shaped her candidacy. Finally, fashion designer Samuel Rose talks about his creative process and an upcoming exhibition.

Leading Black women in S.T.E.M. and beauty.

Hdac3 is a lysine deacetylase that removes acetyl groups from histones and additional proteins. Although Hdac3 functions within mesenchymal lineage skeletal cells are defined, little is known about Hdac3 activities in bone-resorbing osteoclasts. In this study we conditionally deleted Hdac3 within Ctsk-expressing cells and examined the effects on bone modeling and osteoclast differentiation in mice. Hdac3 deficiency reduced femur and tibia periosteal circumference and increased cortical periosteal osteoclast number. Trabecular bone was likewise reduced and was accompanied by increased osteoclast number per trabecular bone surface. We previously showed that Hdac3 deacetylates the p65 subunit of the NF-κB transcriptional complex to decrease DNA-binding and transcriptional activity. Hdac3-deficient osteoclasts demonstrate increased K310 NF-κB acetylation and NF-κB transcriptional activity. Hdac3-deficient osteoclast lineage cells were hyper-responsive to RANKL and showed elevated ex vivo osteoclast number and size and enhanced bone resorption in pit formation assays. Osteoclast-directed Hdac3 deficiency decreased cortical and trabecular bone mass parameters, suggesting that Hdac3 regulates coupling of bone resorption and bone formation. We surveyed a panel of osteoclast-derived coupling factors and found that Hdac3 suppression diminished sphingosine-1-phosphate production. Osteoclast-derived sphingosine-1-phosphate acts in paracrine to promote bone mineralization. Mineralization of WT bone marrow stromal cells cultured with conditioned medium from Hdac3-deficient osteoclasts was markedly reduced. Expression of alkaline phosphatase, type 1a1 collagen, and osteocalcin was also suppressed, but no change in Runx2 expression was observed. Our results demonstrate that Hdac3 controls bone modeling by suppressing osteoclast lineage cell responsiveness to RANKL and coupling to bone formation.

In addition to a delay, Wisconsin had to eliminate certain questions from its Smarter Balanced exam, after opting not to use the adaptive testing feature of the test.

The justices hear arguments Nov. 12 on the Trump administration's effort to end deportation relief under Deferred Action for Childhood Arrivals, in a case pitting the administration and GOP-leaning states against a host of education and advocacy groups.

The court rules that the decision to unwind deportation relief for nearly 700,000 undocumented immigrants who came to the U.S. as children was done in an “arbitrary and capricious” manner.

Title: Nasal Spray May Ease Cluster Headaches
Category: Health News
Created: 8/29/2007 12:00:00 AM
Last Editorial Review: 8/29/2007 12:00:00 AM

Title: Acupuncture Might Ease Tension Headaches
Category: Health News
Created: 6/23/2022 12:00:00 AM
Last Editorial Review: 6/23/2022 12:00:00 AM

Title: What Gets Rid of Headaches Quickly?
Category: Diseases and Conditions
Created: 4/12/2016 12:00:00 AM
Last Editorial Review: 7/17/2022 12:00:00 AM

Title: Pandemic Brought More Woes for Kids Prone to Headaches
Category: Health News
Created: 8/9/2022 12:00:00 AM
Last Editorial Review: 8/10/2022 12:00:00 AM

Family medicine physicians often see headache as the chief complaint when meeting patients within their practice. The goal is to try different treatment modalities without having to send the patient to a specialist. Headaches affect different individuals during their lifetime. Before any treatment begins, it is best that one rules out possible causes of the headache, for example, drug interactions or structural cerebrum conditions. Nonpharmacological treatment is recommended first before attempting a stepwise approach to cost-effective pharmacological treatment options. Pharmacological treatment options should include preventive and on-demand options. A family physician has all the resources to assist patients with different types of headaches.

NPR's Juana Summers talks with Cindy Nava, a Democrat, who will be joining the New Mexico state senate in Albuquerque. She is one of the millions of "Dreamers" who are protected by DACA.