BACKGROUND:Pulmonary function tests (PFTs) have historically used race-specific prediction equations. The recent American Thoracic Society guidelines recommend the use of a race-neutral approach in prediction equations. There are limited studies centering the opinions of practicing pulmonologists on the use of race in spirometry. Provider opinion will impact adoption of the new guideline. The aim of this study was to ascertain the beliefs of academic pulmonary and critical care providers regarding the use of race as a variable in spirometry prediction equations.METHODS:We report data from 151 open-ended responses from a voluntary, nationwide survey (distributed by the Association of Pulmonary Critical Care Medicine Program Directors) of academic pulmonary and critical care providers regarding the use of race in PFT prediction equations. Responses were coded using inductive and deductive methods, and a thematic content analysis was conducted.RESULTS:There was a balanced distribution of opinions among respondents supporting, opposing, or being unsure about the incorporation of race in spirometry prediction equations. Responses demonstrated a wide array of understanding related to the concept and definition of race and its relationship to physiology.CONCLUSIONS:There was no consensus among providers regarding the use of race in spirometry prediction equations. Concepts of race having biologic implications persist among pulmonary providers and will likely affect the uptake of the Global Lung Function Initiative per the American Thoracic Society guidelines.

Extract

As of 15 May 2024, >775 million confirmed cases of COVID-19 and >7 million deaths have been reported to the World Health Organization [1]. Although most patients with COVID-19 survive, survivors are at risk of long COVID, the sequelae of the viral infection affecting multiple organ systems [2]. Long COVID poses a substantial burden to individuals and society, even with a conservative estimate of 10% prevalence among COVID-19 survivors [3–5]. However, as the symptoms of long COVID vary substantially, ranging from respiratory symptoms, such as dyspnoea and cough, to fatigue and cognitive impairment [6], developing a standard set of investigations and management protocols for patients with long COVID is challenging.

Introduction

Exacerbation of COPD complicated by respiratory acidaemia is the commonest indication for noninvasive ventilation (NIV). The NIV outcomes (NIVO) score offers the best estimate of survival for those ventilated. Unfortunately, two-thirds of cases of COPD are unrecognised, and patients may present without COPD having been confirmed by spirometry.

Le texte complet de l’article est aussi disponible en français.

ABSTRACTIntroduction:Health risks associated with short interpregnancy intervals, coupled with women’s desires to avoid pregnancy following childbirth, underscore the need for effective postpartum family planning programs. The antenatal period provides an opportunity to intervene; however, evidence is limited on the effectiveness of interventions aimed at reaching women in the antenatal period to increase voluntary postpartum family planning in low- and middle-income countries (LMICs). This systematic review aimed to identify and describe interventions in LMICs that attempted to increase postpartum contraceptive use via contacts with pregnant women in the antenatal period.Methods:Studies published from January 2012 to July 2022 were considered if they were conducted in LMICs, evaluated an intervention delivered during the antenatal period, were designed to affect postpartum contraceptive use, were experimental or quasi-experimental, and were published in French or English. The main outcome of interest was postpartum contraceptive use within 1 year after birth, defined as the use of any method of contraception at the time of data collection. We searched EMBASE, Global Health, and Medline and manually searched the reference lists from studies included in the full-text screening.Results:We double-screened 771 records and included 34 reports on 31 unique interventions in the review. Twenty-three studies were published from 2018 on, with 21 studies conducted in sub-Saharan Africa. Approximately half of the study designs (n=16) were randomized controlled trials, and half (n=15) were quasi-experimental. Interventions were heterogeneous. Among the 24 studies that reported on the main outcome of interest, 18 reported a positive intervention effect, with intervention recipients having greater contraceptive use in the first year postpartum.Conclusion:While the studies in this systematic review were heterogeneous, the findings suggest that interventions that included a multifaceted package of initiatives appeared to be most likely to have a positive effect.

Low-efficacy mu opioid receptor (MOR) agonists may serve as novel candidate analgesics with improved safety relative to high-efficacy opioids. This study used a recently validated assay of pain-depressed behavior in mice to evaluate a novel series of MOR-selective C9-substituted phenylmorphan opioids with graded MOR efficacies. Intraperitoneal injection of dilute lactic acid (IP acid) served as a noxious stimulus to depress locomotor activity by mice in an activity chamber composed of two compartments connected by an obstructed door. Behavioral measures included (1) crosses between compartments (vertical activity over the obstruction) and (2) movement counts quantified as photobeam breaks summed across compartments (horizontal activity). Each drug was tested alone and as a pretreatment to IP acid. A charcoal-meal test and whole-body-plethysmography assessment of breathing in 5% CO₂ were also used to assess gastrointestinal (GI) inhibition and respiratory depression, respectively. IP acid produced a concentration-dependent depression in crosses and movement that was optimally alleviated by intermediate- to low-efficacy phenylmorphans with sufficient efficacy to produce analgesia with minimal locomotor disruption. Follow-up studies with two low-efficacy phenylmorphans (JL-2-39 and DC-1-76.1) indicated that both drugs produced naltrexone-reversible antinociception with a rapid onset and a duration of ~1 h. Potency of both drugs increased when behavior was depressed by a lower IP-acid concentration, and neither drug alleviated behavioral depression by a non-pain stimulus (IP lithium chloride). Both drugs produced weaker GI inhibition and respiratory depression than fentanyl and attenuated fentanyl-induced GI inhibition and respiratory depression. Results support further consideration of selective, low-efficacy MOR agonists as candidate analgesics.

The diagnostic work-up of patients with fever of unknown origin (FUO) begins with a thorough history and physical examination, complete blood count with differential, chest x-ray, urinalysis and culture, electrolyte panel, liver enzymes, erythrocyte sedimentation rate, and C-reactive protein level. Additional imaging procedures, including nuclear medicine tests, are generally used as second-line procedures, with ¹⁸F-FDG PET and PET/CT assuming increasingly important roles in the diagnostic work-up. The Society of Nuclear Medicine and Molecular Imaging, the Infectious Diseases Society of America, and the American College of Nuclear Medicine convened an autonomous expert work group to comprehensively review the published literature for nuclear imaging in adults and children with FUO and establish appropriate use criteria (AUC). This process was performed in accordance with the Protecting Access to Medicare Act of 2014, which requires that all referring physicians consult AUC by using a clinical decision support mechanism before ordering advanced diagnostic imaging services. The complete findings and discussions of the work group were published on January 8, 2023, and are available at https://www.snmmi.org/ClinicalPractice/content.aspx?ItemNumber=15666. The AUC in the final document are intended to assist referring health care providers in appropriate use of nuclear medicine imaging procedures in patients with FUO. The work group noted limitations in the current literature on nuclear medicine imaging for FUO, with the need for well-designed prospective multicenter investigations. Consensus findings from published data and expert opinions were used to create recommendations in common clinical scenarios for adults and children. Included in the complete document is a discussion of inflammation of unknown origin (IUO), a recently described entity. In view of the fact that the criteria for FUO and IUO are similar (except for fever > 38.3°C [100.9°F]) and that the most common etiologies of these 2 entities are similar, it is the expert opinion of the work group that the recommendations for nuclear medicine imaging of FUO are also applicable to IUO. These recommendations are included in the full guidance document. This summary reviews rationale, methodology, and main findings and refers the reader to the complete AUC document.

BACKGROUND AND PURPOSE:

Low-field 64 mT portable brain MRI has recently shown diagnostic promise for MS. This study aimed to evaluate the utility of portable MRI (pMRI) in assessing dissemination in space (DIS) in patients presenting with optic neuritis and determine whether deploying pMRI in the MS clinic can shorten the time from symptom onset to MRI.

BACKGROUND AND PURPOSE:

Percutaneous cement augmentation has been reported as an effective salvage procedure for frail patients with spinal instrumentation failure, such as screw loosening, hardware breakage, cage subsidence, and fractures within or adjacent to stabilized segments. Favorable results were reported during a median follow-up period of 16 months in a retrospective analysis of 31 consecutive procedures performed in 29 patients. In the present study, the long-term effectiveness of this treatment in avoiding or postponing revision surgery is reported.

BACKGROUND AND PURPOSE:

Neuronal ceroid lipofuscinoses are a group of neurodegenerative disorders. Recently, enzyme replacement therapy (ERT) was approved for neuronal ceroid lipofuscinosis type 2 (CLN2), a subtype of neuronal ceroid lipofuscinoses. The aim of this study was to quantify brain volume loss in CLN2 disease in patients on ERT in comparison with a natural history cohort using MRI.

BACKGROUND AND PURPOSE:

Gadolinium-based contrast agents are widely used for meningioma imaging; however, concerns exist regarding their side effects, cost, and environmental impact. At the standard gadolinium dose, most meningiomas show avid contrast enhancement, suggesting that administering a smaller dose may be feasible. The purpose of this study was to evaluate the impact of a lower gadolinium dose on the differentiation between meningiomas and adjacent intracranial tissues.

BACKGROUND AND PURPOSE:

Prediction of aneurysm instability is crucial to guide treatment decisions and to select appropriate patients with unruptured intracranial aneurysms (IAs) for preventive treatment. High-resolution 4D MR flow imaging and 3D quantification of aneurysm morphology could offer insights and new imaging markers for aneurysm instability. In this cross-sectional study, we aim to identify 4D MR flow imaging markers for aneurysm instability by relating hemodynamics in the aneurysm sac to 3D morphologic proxy parameters for aneurysm instability.

Pilocytic astrocytomas are the most common pediatric brain tumors, typically presenting as low-grade neoplasms. We report two cases of pilocytic astrocytoma with atypical tumor progression. Case 1 involves a 12-yr-old boy with an unresectable suprasellar tumor, negative for BRAF rearrangement but harboring a BRAF p.V600E mutation. He experienced tumor size reduction and stable disease following dabrafenib treatment. Case 2 describes a 6-yr-old boy with a thalamic tumor that underwent multiple resections, with no actionable driver detected using targeted next-generation sequencing. Whole-genome and RNA-seq analysis identified an internal tandem duplication in FGFR1 and RAS pathway activation. Future management options include FGFR1 inhibitors. These cases demonstrate the importance of escalating molecular diagnostics for pediatric brain cancer, advocating for early reflexing to integrative whole-genome sequencing and transcriptomic profiling when targeted panels are uninformative. Identifying molecular drivers can significantly impact treatment decisions and improve patient outcomes.

Practicing family medicine is really hard; the emotional toll of sharing patients’ distress, vulnerability, and trauma can build up and become overwhelming. A family physician experienced such a moment during one particularly complex morning. Feeling nearly ready to walk out of patient care, she reached out to the team nurse, who helped her get through the moment and re-engage with the waiting patients. Sharing vulnerability in the moment, and later reflecting and deciding to write about it shows the power of prioritizing teamwork in practice.

Patient expectations of receiving antibiotics for common symptoms can trigger unnecessary use. We conducted a survey (n = 564) between January 2020 to June 2021 in public and private primary care clinics in Texas to study the prevalence and predictors of patients’ antibiotic expectations for common symptoms/illnesses. We surveyed Black patients (33%) and Hispanic/Latine patients (47%), and over 93% expected to receive an antibiotic for at least 1 of the 5 pre-defined symptoms/illnesses. Public clinic patients were nearly twice as likely to expect antibiotics for sore throat, diarrhea, and cold/flu than private clinic patients. Lack of knowledge of potential risks of antibiotic use was associated with increased antibiotic expectations for diarrhea (odds ratio [OR] = 1.6; 95% CI, 1.1-2.4) and cold/flu symptoms (OR = 2.9; 95% CI, 2.0-4.4). Lower education and inadequate health literacy were predictors of antibiotic expectations for diarrhea. Future antibiotic stewardship interventions should tailor patient education materials to include information on antibiotic risks and guidance on appropriate antibiotic indications.

The aim of this work is to test whether the use of a transparent capsule affects the residual capsule weight after inhalation as a surrogate of the inhaled delivered dose for patients with non-reversible chronic airway disease. Researchers conducted an observational cross-sectional study with patients using a single-dose dry powder inhaler. The weight of the capsule was measured with a precision microbalance before and after inhalation. Ninety-one patients were included, of whom 63 (69.2%) used a transparent capsule. Inhalation with a transparent capsule achieved a weight decrease of 30.1% vs 8.6% for devices with an opaque capsule (P <0.001). These data reinforce the need to provide patients with mechanisms that verify the correct inhalation technique.

PURPOSE

The impact of digital health on medically underserved patients is unclear. This study aimed to determine the early impact of a digital innovation to grow quality care through an interprofessional care team (DIG IT) on the blood pressure (BP) and 10-year atherosclerotic cardiovascular disease (ASCVD) risk score of medically underserved patients.

The strength of reproductive isolation (RI) between two or more lineages during the process of speciation can vary by the ecological conditions. However, most speciation research has been limited to studying how ecologically dependent RI varies among a handful of broadly categorized environments. Very few studies consider the variability of RI and its effects on speciation at finer scales—that is, within each environment due to spatial or temporal environmental heterogeneity. Such variation in RI across time and/or space may inhibit speciation through leaky reproductive barriers or promote speciation by facilitating reinforcement. To investigate this overlooked aspect of speciation research, we conducted a literature review of existing studies of variation in RI in the field and then conducted individual-based simulations to examine how variation in hybrid fitness across time and space affects the degree of gene flow. Our simulations indicate that the presence of variation in hybrid fitness across space and time often leads to an increase in gene flow compared to scenarios where hybrid fitness remains static. This observation can be attributed to the convex relationship between the degree of gene flow and the strength of selection on hybrids. Our simulations also show that the effect of variation in RI on facilitating gene flow is most pronounced when RI, on average, is relatively low. This finding suggests that it could serve as an important mechanism to explain why the completion of speciation is often challenging. While direct empirical evidence documenting variation in extrinsic RI is limited, we contend that it is a prevalent yet underexplored phenomenon. We support this argument by proposing common scenarios in which RI is likely to exhibit variability and thus influence the process of speciation.

Surprisingly little attention has been given to the impact of selfing on speciation, even though selfing reduces gene flow between populations and affects other key population genetics parameters. Here we review recent theoretical work and compile empirical data from crossing experiments and genomic and phylogenetic studies to assess the effect of mating systems on the speciation process. In accordance with theoretical predictions, we find that accumulation of hybrid incompatibilities seems to be accelerated in selfers, but there is so far limited empirical support for a predicted bias toward underdominant loci. Phylogenetic evidence is scarce and contradictory, including studies suggesting that selfing either promotes or hampers speciation rate. Further studies are therefore required, which in addition to measures of reproductive barrier strength and selfing rate should routinely include estimates of demographic history and genetic divergence as a proxy for divergence time.

Bone marrow transplantation, now often known as haematopoietic stem cell transplantation (HSCT), is a complex choreographed procedure used to treat both acquired and inherited disorders of the bone marrow. It has proven invaluable as therapy for haematological and immunological disorders, and more recently in the treatment of metabolic and enzyme disorders. As the number of performed transplants grows annually, and with patients enjoying improved survival, a knowledge of both early and late complications of HSCT is essential for respiratory trainees and physicians in practice. This article highlights the spectrum of respiratory complications, both infectious and non-infectious, the timeline of their likely occurrence, and the approaches used for diagnosis and treatment, keeping in mind that more than one entity may occur simultaneously. As respiratory issues are often a leading cause of short- and long-term morbidity, consideration of a combined haematology/respiratory clinic may prove useful in this patient population.

A nudibranch from the midnight zone has fingers on its tail, collects food with a hood, and glows.

Season six's latest episode introduced Laszlo's father—and chaos inevitably followed.

Tim Miller hopes Amazon's anthology series will help viewers appreciate the "blood, sweat, and tears" Firewalk Studios put into the scrapped game.

Trump seems to have just two options.

The current growth and consumption based economy is not sustainable. The world must move towards a circular economy and sustainability.

The post Degrowth, green energy, social equity, and circular economy appeared first on rabble.ca.

With 420,000 Quebec public sector workers on strike on Monday, and with little progress in negotiations, the Front Commun promises further strike action.

The post Hundreds of thousands of Quebec public sector workers vow further strike action appeared first on rabble.ca.

The City of Vancouver council has reneged on a previous commitment to a living wage for its employees.

The post City of Vancouver to lowest paid workers: Let them eat cuts! appeared first on rabble.ca.

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JUDY WOODRUFF: Longstanding rivalries were re-ignited in Iraq today between vital American allies.

Iraqi military forces and militia moved to push Kurdish forces out of the disputed city of Kirkuk in the country’s north.

Lisa Desjardins begins our coverage.

MAN (through interpreter): The commander in chief of the armed forces, Dr. Haider al-Abadi, gave orders to protect the people of Kirkuk and to impose security in the city.

LISA DESJARDINS: After months of simmering tensions, Iraqi federal troops moved to retake the disputed city of Kirkuk from Kurdish forces.

The effort launched before dawn. By midday, Iraqi soldiers, along with state-backed militias, quickly took control of several massive oil fields north of the city. Iraqis also captured Kirkuk’s military airport and various government buildings. They lowered what had been a symbolic Kurdish flag at the governor’s compound.

Journalist Rebecca Collard in Irbil was in Kirkuk this morning.

REBECCA COLLARD, Journalist: You could hear some clashes, some gunfire in the distance, but for the most part, the city seemed more or less abandoned. Now, the Iraqi army, by the end of today, was essentially in control of the whole city and many of the outskirts of Kirkuk.

LISA DESJARDINS: The spokesman for an Iraqi Shiite militia said they achieved all their goals with little resistance.

AHMED AL-ASSADI,  Spokesman for al-Hashed al-Shaabi (through translator): As the troops approached the area, they were confronted by some rebels, who tried to hinder the progress of the advancing units. Our troops returned fire and silenced its source.

LISA DESJARDINS: This comes three weeks after the Kurds held a nonbinding independence referendum that included the disputed province of Kirkuk.

More than 90 percent of the Kurdish region’s residents voted to split from Iraq. The Iraqi federal government, Turkey, Iran and the U.S. all rejected the independence drive.

The multiethnic region of Kirkuk lies just outside of the autonomous Kurdish region in Iraq’s north. Called the country’s oil capital, Kirkuk produces around 500,000 barrels a day.

In 2014, amid the ISIS onslaught across Northern Iraq, the Kurds took control of Kirkuk, as the Iraqi military fled the city. In the three years since, the Kurds, led by their president, Massoud Barzani, sought to cement their hold, despite tensions with the central government.

Today, Kurdish officials accused Iraq of carrying out a major multipronged attack.

MAJ. GEN. AYOUB YUSUF SAID, Peshmerga Commander (through interpreter): I don’t know what is happening exactly, because we have been in this fight since 4:00 in the morning. We have suffered casualties, including martyrs, and now we have withdrawn to this position. Some of the other Kurdish forces have pulled out. They didn’t fire a single shot.

LISA DESJARDINS: While Kurdish forces withdrew from posts south of the city, some residents vowed to die fighting. Thousands of others fled north.

REBECCA COLLARD: For the last few years, the Iraqi forces, these primarily Shia militia, the Hashed Shaabi, and the Kurdish forces have been focused on fighting ISIS. Now that fight is coming to an end, and what the fear is that now these internal division in Iraq are going to become more apparent and possibly more violent.

LISA DESJARDINS: These clashes pit one substantially American-armed military force against another. Both the Kurdish forces and Iraqi government troops are part of the coalition fighting ISIS. The U.S. sought to downplay the fighting, labeling the exchange of gunfire a misunderstanding.

And, in the Rose Garden, President Trump tried to stay neutral.

PRESIDENT DONALD TRUMP: We don’t like the fact that they’re clashing. We’re not taking sides. But we don’t like the fact that they’re clashing.

LISA DESJARDINS: For the PBS NewsHour, I’m Lisa Desjardins.

JUDY WOODRUFF: For more, I’m joined now by Emma Sky. She served as an adviser to General David Petraeus while he was commander of U.S. forces in Iraq from 2007 to 2010, and by Feisal Istrabadi. He’s a former Iraqi ambassador to the United Nations and he helped write Iraq’s interim constitution.

Welcome to both of you.

Let me start with you, Emma Sky.

This has happened so quickly. What exactly has the Iraqi government done?

EMMA SKY, Yale University: The Iraqi government has deployed its forces back up north into Kirkuk.

And since 2003, the Kurds have made it clear that they want to include Kirkuk within their territory in order to proceed with gaining independence, which has always been their goal. But Kirkuk is important to Iraq itself, and no Iraqi prime minister can afford to lose Kirkuk.

So you can see this reaction that has taken place following the referendum on independence, which happened September the 25th, and also included the disputed territories and the city of Kirkuk.

JUDY WOODRUFF: Feisal Istrabadi, what can you add to why the Iraqi government is so set on taking over the city?

FEISAL ISTRABADI, Former Deputy UN Ambassador, Iraq: Well, a couple of reasons.

First, as Emma just said, it is a part of the disputed territories, which are legally and constitutionally under the jurisdiction of the federal government in Baghdad. The KRG expanded into these disputed territories at the time when ISIL was expanding its territory, and then began to take steps to unilaterally declare that these areas were now incorporated into the Kurdistan region, including when it held the referendum that Emma talked about.

It included holding the referendum in these disputed territories. Now, so long as Iraq — so long as we’re talking about a single country, it matters a little less who controls Kirkuk, but once the referendum was held, this gave rise then to the second reason for Baghdad choosing to act now.

As Emma said, Kirkuk is an important oil-producing zone in Iraq. And it is vital for the economic viability of an independent Kurdish state and an important part of the economic viability of the Iraqi state. So there was never going to be a scenario, I think, in which Baghdad would allow a unilateral exercise of control by Kurds to occur over Kirkuk, so long as independence is on the table.

JUDY WOODRUFF: Emma Sky, we heard President Trump say today the U.S. is not taking sides in this.

Is that accurate, that the U.S. isn’t taking sides? What is the U.S. role here?

EMMA SKY: Well, the U.S. has stipulated over and over again that its policy is to support a united Iraq.

So you can see the U.S. has given support to Iraqi security forces, but also to the Kurdish Peshmerga, to fight against ISIS. The U.S. policy for the last few years has really been focused on ISIS and not on the day after ISIS.

But what we’re witnessing at the moment is that different groups are already moving to the day after, which is the power struggle for control of different territories in Iraq.

And Barzani believed that during the fight against ISIS, he became stronger because he got weapons directly from the international community. And, as Feisal said, he was able to extend his control over the disputed territories.

He’s also facing domestic problems within Kurdistan. There are tensions between the different Kurdish groups, and some believe that Barzani has overstayed his term as president.

JUDY WOODRUFF: Which reminds us just how complicated this is, Feisal Istrabadi.

What does the Iraqi central government want here? They’re not going to get rid of the Kurds. What is it that they want?

FEISAL ISTRABADI: Oh, well, I mean, the Kurds of course are a vital part of Iraq. They’re a vital part of the political process, and they have been represented in Baghdad. The president of Iraq is a Kurd and has been since 2005.

I think what needs to occur and I hope what the government of Iraq wants is a negotiated settlement, in which no party dictates terms to the other, but a negotiated settlement.

Look, Irbil has some legitimate agreements with respect to Baghdad. Baghdad has some legitimate agreements with respect to Irbil. I think we need a mediator perhaps or somebody to convene a roundtable — the United States is who I’m thinking of, of course — to address some of those issues.

Most of the issues are, from the Irbil side, economic issues of payments, and from Baghdad’s side, transparency of how much oil Irbil is producing and exporting, which Irbil has never accounted for to Baghdad.

I think if those issues are resolved, perhaps hopefully some of these other issues can at least be delayed for another day. But at the end of the day, neither government — neither the regional government nor the federal government in Baghdad can really tolerate dictation of terms to it by the other side. My hope is that a negotiated settlement obtains.

JUDY WOODRUFF: Emma Sky, where do you see this going from here? Do you see the peace that different sides have worked to hard to create in Iraq unraveling as a result of this?

EMMA SKY: I think there is an opportunity for a deal, and I think the sort of deal that could be negotiated is one that looks at a special status for the city of Kirkuk and negotiated terms for Kurdistan’s separate, whether that be towards confederation or towards independence.

But there needs to be negotiation. There needs to be a look at where should the border between Iraqi Kurdistan and the rest of Iraq actually be, and that requires mediation district by district through those territories.

JUDY WOODRUFF: Well, we know there are other players who are playing an important role here in Iran and Turkey, and this is all very much playing out as we watch, watch it happen in Iraq.

Emma Sky, Feisal Istrabadi, thank you very much.

FEISAL ISTRABADI: Thank you.

EMMA SKY: Thank you.

The post Why a power struggle has broken out over Kirkuk appeared first on PBS NewsHour.

More than 500,000 Rohingya Muslims have fled their homes since August to escape systematic violence at the hands of government soldiers in Myanmar. The U.N. has called the actions taken by Myanmar forces against the group “a textbook example of ethnic cleansing.”

A report released by Amnesty International on Wednesday documents widespread rape, killings and burnings of Rohingya across the Rakhine State in Myanmar. The report includes extensive interviews of Rohingya refugees who tell stories of live burnings, sexual violence and mass shootings at the hands of soldiers.

To escape persecution, Rohingya refugees are fleeing in droves to neighboring Bangladesh, a country described by some as a reluctant host for the thousands of refugees behind its borders. Conditions within Bangladesh show refugee camps beyond capacity, as organizations struggle to keep up with humanitarian aid.

Find out more: Rohingya Muslims have been denied citizenship in Myanmar since 1982, though they’ve lived in the area since the 12th century. They are not considered one of the country’s official ethnic groups. As such, their lack of official identity bars them from government services and travel.

Officials from Myanmar, a majority Buddhist state, claim Rohingya are actually immigrants from Bangladesh to justify their exclusion of the group. This most recent burst of violence comes from Myanmar’s crackdown following clashes with the Arakan Rohingya Salvation Army (ARSA). After the government declared ARSA a terrorist organization, the retaliation escalated into hundreds of Rohingya villages.

Where to give: BRAC, a top-ranked NGO based out of Bangladesh, is scaling up humanitarian efforts for clean water, health, sanitation and child care for refugees from Myanmar. You can learn more about their efforts here.

An emergency appeal was made by the Disasters Emergency Committee for immediate crisis relief funds. DEC distributes funds to 13 member aid organizations.
UNHCR, UNICEF and Save the Children have donation pages dedicated to the crisis, as does the International Rescue Committee. CNN’s Public Good page provides a user-friendly resource to find NGOs that match your giving goals.

To give to starvation relief, try Action Against Hunger or the World Food Programme.

Be sure to research organizations receiving your financial contributions, not only to find the best organization aligned with your goals, but also to avoid potential scams. For the latest information on aid organizations and charities, visit GuideStar or Charity Navigator to ensure your donations are going in the right direction.

The post As Rohingya refugees continue to flee from persecution, here’s how you can help appeared first on PBS NewsHour.

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HARI SREENIVASAN: President Xi Jinping opened China’s twice-per-decade Communist Party Congress today with a lengthy list of his achievements during his first five-year term, and his vision of where he hopes to take his nation.

But beyond the words, Xi is asserting power like no Chinese leader in decades.

William Brangham reports.

WILLIAM BRANGHAM: The applause, the music, it was a reception befitting the commanding role that Xi Jinping has taken since being named party leader five years ago.

He opened today’s proceedings by hailing reforms he’s put in place, and proclaiming a — quote — “new era for China.”

PRESIDENT XI JINPING, China (through interpreter): The Chinese nation has realized a great leap, from declining in modern history to twisting its fate fundamentally and continuously moving to prosperity.

WILLIAM BRANGHAM: Over 3.5 hours, Xi laid out his vision to shape the nation of 1.4 billion people into what he called a — quote — “great modern socialist country” over the next three decades.

PRESIDENT XI JINPING (through interpreter): Achieving the great rejuvenation of the Chinese nation will be no walk in the park, and it will take more than drumbeating and gong-clanging to get there. The whole party must be prepared to make more arduous, strenuous efforts.

WILLIAM BRANGHAM: Susan Shirk is chair of the 21st Century China Center at the University of California, San Diego.

SUSAN SHIRK, University of California, San Diego: Xi Jinping has a vision of China’s role in the world that is much more ambitious than anything we have seen before, talking about China kind of moving toward the center of the world and having a lot more influence than it did before.

WILLIAM BRANGHAM: In his address, Xi largely ignored the question of political reforms in China, and he didn’t mention President Trump or North Korea’s nuclear weapons program.

But in a rare move, he did acknowledge that with global demand weakening, there were challenges facing China’s export-driven economy.

PRESIDENT XI JINPING (through interpreter):  While China’s overall productive forces have significantly improved and in many areas our production capacity leads the world, the more prominent problem is that our development is unbalanced and inadequate.

WILLIAM BRANGHAM: Xi was one of the first foreign leaders to meet with President Trump.

PRESIDENT DONALD TRUMP: The relationship developed by President Xi and myself, I think, is outstanding.

WILLIAM BRANGHAM: That was decidedly warmer than Mr. Trump’s past criticism of China and its economic and trade policies.

But other U.S. officials are more critical of Beijing’s actions.

REX TILLERSON, Secretary of State: China, while rising alongside India, has done so less responsibly.

WILLIAM BRANGHAM: Secretary of State Rex Tillerson today criticized China’s aggressive displays of economic and military power, particularly its expansion on man-made islands in the South China Sea.

REX TILLERSON: We will not shrink from China’s challenges to the rules-based order, and where China subverts the sovereignty of neighboring countries and disadvantages the U.S. and our friends.

SUSAN SHIRK: I think there are things to worry about in Chinese foreign policy that are mostly related to these maritime sovereignty issues and to a kind of bullying in Asia, but the global ambition could turn out to be positive.

WILLIAM BRANGHAM: Susan Shirk says China has filled a vacuum left by the United States’ withdrawal from global agreements like the Trans-Pacific Partnership and the Paris climate accords.

Perhaps the most important thing to watch for in the next few days is who Xi establishes as his likely successor.

SUSAN SHIRK: That is why there is a lot of speculation now that he may be trying, much like Putin, to stay on beyond his normal term or to rule behind the scenes even after he retires.

WILLIAM BRANGHAM: President Trump will be traveling to Beijing to meet Xi next month.

For the PBS NewsHour, I’m William Brangham.

The post Xi Jinping celebrates China’s rising power — and his own appeared first on PBS NewsHour.

RADIO shock jock fan Alan Jones unleashed on both sides of politics on Q&A last night — and came out in defence of Brexit.

"Kate Forbes still has her own leadership ambitions, setting them aside this Spring in the interest of party unity to accept Mr Swinney's offer to become Deputy First Minister."

Ministers must follow the UK Government and extend rates relief for businesses in Scotland, Anas Sarwar has said.

AS the nights draw in, and we wake up and it’s still dark out, it just feels that little harder to get out of bed. For some, however, kicking off those warm, cosy covers is far harder than for others.

The flats are described as the first new homes on the Scottish town's High Street 'in living memory'

A "renowned" restructuring advisory business has been acquired by a major player.

The accountancy firm has opened a new office in the Scottish town

Emergency services were called to the Glebe Place area of the town

A Scottish distillery has hailed the opening of a new 'dining destination' amid an expansion push.

Sir Andy Murray will swap Centre Court for the stage next summer as he embarks on a tour discussing his illustrious tennis career.

Jonathan Stringer joins this week and helps Major Tomcat recruit Kelley and Chris for a PC RPG. Chris will likely just hack the planet instead. Kelley, meanwhile, will tend to her cat's bad habits.

The post RPG Cast – Episode 554: “Cat Smoker Meow” appeared first on RPGamer.

Chris does an Xbox 180 while Josh steals Anna Marie's needle. Robert gets the snotty kleenex award because he can't figure out how to stream Suikoden. And Kelley is too busy fawning over Revali to notice.

The post RPG Cast – Episode 570: “Kmart Cowboy Bebop” appeared first on RPGamer.

It's just the core trio this week, as Chris tosses a coin to his hunting horn partner Kelley, and Anna Marie rolls her eyes as Chris cracks terrible jokes about what the Vita really means. We all consider MiHoYo's bottom line, as well as whether we're classified as normies.

The post RPG Cast – Episode 580: “Marshmallow Is Canon” appeared first on RPGamer.