rom Glycated Hemoglobin, Prediabetes, and the Links to Cardiovascular Disease: Data From UK Biobank By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE HbA1c levels are increasingly measured in screening for diabetes; we investigated whether HbA1c may simultaneously improve cardiovascular disease (CVD) risk assessment, using QRISK3, American College of Cardiology/American Heart Association (ACC/AHA), and Systematic COronary Risk Evaluation (SCORE) scoring systems. RESEARCH DESIGN AND METHODS UK Biobank participants without baseline CVD or known diabetes (n = 357,833) were included. Associations of HbA1c with CVD was assessed using Cox models adjusting for classical risk factors. Predictive utility was determined by the C-index and net reclassification index (NRI). A separate analysis was conducted in 16,596 participants with known baseline diabetes. RESULTS Incident fatal or nonfatal CVD, as defined in the QRISK3 prediction model, occurred in 12,877 participants over 8.9 years. Of participants, 3.3% (n = 11,665) had prediabetes (42.0–47.9 mmol/mol [6.0–6.4%]) and 0.7% (n = 2,573) had undiagnosed diabetes (≥48.0 mmol/mol [≥6.5%]). In unadjusted models, compared with the reference group (<42.0 mmol/mol [<6.0%]), those with prediabetes and undiagnosed diabetes were at higher CVD risk: hazard ratio (HR) 1.83 (95% CI 1.69–1.97) and 2.26 (95% CI 1.96–2.60), respectively. After adjustment for classical risk factors, these attenuated to HR 1.11 (95% CI 1.03–1.20) and 1.20 (1.04–1.38), respectively. Adding HbA1c to the QRISK3 CVD risk prediction model (C-index 0.7392) yielded a small improvement in discrimination (C-index increase of 0.0004 [95% CI 0.0001–0.0007]). The NRI showed no improvement. Results were similar for models based on the ACC/AHA and SCORE risk models. CONCLUSIONS The near twofold higher unadjusted risk for CVD in people with prediabetes is driven mainly by abnormal levels of conventional CVD risk factors. While HbA1c adds minimally to cardiovascular risk prediction, those with prediabetes should have their conventional cardiovascular risk factors appropriately measured and managed. Full Article
rom Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE We sought to confirm a bidirectional association between severe hypoglycemic events (SHEs) and cardiovascular (CV) event risk and to characterize individuals at dual risk. RESEARCH DESIGN AND METHODS In a post hoc analysis of 14,752 Exenatide Study of Cardiovascular Event Lowering (EXSCEL) participants, we examined time-dependent associations between SHEs and subsequent major adverse cardiac events (CV death, nonfatal myocardial infarction [MI] or stroke), fatal/nonfatal MI, fatal/nonfatal stroke, hospitalization for acute coronary syndrome (hACS), hospitalization for heart failure (hHF), and all-cause mortality (ACM), as well as time-dependent associations between nonfatal CV events and subsequent SHEs. RESULTS SHEs were uncommon and not associated with once-weekly exenatide therapy (hazard ratio 1.13 [95% CI 0.94–1.36], P = 0.179). In fully adjusted models, SHEs were associated with an increased risk of subsequent ACM (1.83 [1.38–2.42], P < 0.001), CV death (1.60 [1.11–2.30], P = 0.012), and hHF (2.09 [1.37–3.17], P = 0.001), while nonfatal MI (2.02 [1.35–3.01], P = 0.001), nonfatal stroke (2.30 [1.25–4.23], P = 0.007), hACS (2.00 [1.39–2.90], P < 0.001), and hHF (3.24 [1.98–5.30], P < 0.001) were all associated with a subsequent increased risk of SHEs. The elevated bidirectional time-dependent hazards linking SHEs and a composite of all CV events were approximately constant over time, with those individuals at dual risk showing higher comorbidity scores compared with those without. CONCLUSIONS These findings, showing greater risk of SHEs after CV events as well as greater risk of CV events after SHEs, validate a bidirectional relationship between CV events and SHEs in patients with high comorbidity scores. Full Article
rom Immigrant Families and Child Welfare Systems: Emerging Needs and Promising Policies By www.migrationpolicy.org Published On :: Mon, 22 Apr 2019 10:26:23 -0400 With the children of immigrants a growing share of all U.S. children, and federal immigration enforcement and other policies undergoing significant change, some state and local child welfare agencies are developing new ways to improve how they work with immigrant families. This report examines key cultural, linguistic, and legal challenges, and how agencies are adjusting staffing, training, placement, and other policies to tackle them. Full Article
rom Can a Company be pro-regulation and pro-commerce? Gregg Renfrew from Beautycounter thinks so By brandleadership.wordpress.com Published On :: Fri, 19 Feb 2016 18:59:09 +0000 It’s the middle of an election year and, according to the Pew Research Center, the country hasn’t been this polarized since the Civil War. In such a climate, it would seem to be an oxymoron for a company to push for both financial growth and tighter regulations. Gregg Renfrew, CEO & Founder of Beautycounter, wouldn’t […] Full Article *Gabriela Torres Patiño Brand Strategy Business Values Customer Experience Event Marketing
rom Thinking with AND: Insights from KIND’s story By brandleadership.wordpress.com Published On :: Fri, 24 Jun 2016 16:29:46 +0000 “I’m a confused Mexican Jew.” So says Daniel Lubetzky, Founder and CEO of KIND Snack, in his very personal interview with Columbia faculty member David Rogers at BRITE ’16. Their discussion touched on the many ideas behind KIND Snacks, from the beginnings of the company, to the strategic thinking that forces Lubetzky to stay away […] Full Article *Gabriela Torres Patiño Brand Strategy Brand Value Business Values Consumer Insights Event Leadership Marketing Video
rom 10 Examples of Heroism Arising From the COVID-19 Pandemic By blog.richmond.edu Published On :: Sat, 04 Apr 2020 20:26:56 +0000 By Scott T. Allison In any tragedy or crisis, you will see many people standing out and stepping up to save lives and make the world a better place. These heroic individuals can range from leaders of nations to ordinary citizens who rise to the occasion to help others in need. During this COVID-19 pandemic, … Continue reading 10 Examples of Heroism Arising From the COVID-19 Pandemic → Full Article Commentary and Analysis COVID19 heroes
rom No-Failure Design and Disaster Recovery: Lessons from Fukushima By decisions-and-info-gaps.blogspot.com Published On :: Tue, 09 Aug 2011 10:21:00 +0000 One of the striking aspects of the early stages of the nuclear accident at Fukushima-Daiichi last March was the nearly total absence of disaster recovery capability. For instance, while Japan is a super-power of robotic technology, the nuclear authorities had to import robots from France for probing the damaged nuclear plants. Fukushima can teach us an important lesson about technology.The failure of critical technologies can be disastrous. The crash of a civilian airliner can cause hundreds of deaths. The meltdown of a nuclear reactor can release highly toxic isotopes. Failure of flood protection systems can result in vast death and damage. Society therefore insists that critical technologies be designed, operated and maintained to extremely high levels of reliability. We benefit from technology, but we also insist that the designers and operators "do their best" to protect us from their dangers.Industries and government agencies who provide critical technologies almost invariably act in good faith for a range of reasons. Morality dictates responsible behavior, liability legislation establishes sanctions for irresponsible behavior, and economic or political self-interest makes continuous safe operation desirable.The language of performance-optimization − not only doing our best, but also achieving the best − may tend to undermine the successful management of technological danger. A probability of severe failure of one in a million per device per year is exceedingly − and very reassuringly − small. When we honestly believe that we have designed and implemented a technology to have vanishingly small probability of catastrophe, we can honestly ignore the need for disaster recovery.Or can we?Let's contrast this with an ethos that is consistent with a thorough awareness of the potential for adverse surprise. We now acknowledge that our predictions are uncertain, perhaps highly uncertain on some specific points. We attempt to achieve very demanding outcomes − for instance vanishingly small probabilities of catastrophe − but we recognize that our ability to reliably calculate such small probabilities is compromised by the deficiency of our knowledge and understanding. We robustify ourselves against those deficiencies by choosing a design which would be acceptable over a wide range of deviations from our current best understanding. (This is called "robust-satisficing".) Not only does "vanishingly small probability of failure" still entail the possibility of failure, but our predictions of that probability may err.Acknowledging the need for disaster recovery capability (DRC) is awkward and uncomfortable for designers and advocates of a technology. We would much rather believe that DRC is not needed, that we have in fact made catastrophe negligible. But let's not conflate good-faith attempts to deal with complex uncertainties, with guaranteed outcomes based on full knowledge. Our best models are in part wrong, so we robustify against the designer's bounded rationality. But robustness cannot guarantee success. The design and implementation of DRC is a necessary part of the design of any critical technology, and is consistent with the strategy of robust satisficing.One final point: moral hazard and its dilemma. The design of any critical technology entails two distinct and essential elements: failure prevention and disaster recovery. What economists call a `moral hazard' exists since the failure prevention team might rely on the disaster-recovery team, and vice versa. Each team might, at least implicitly, depend on the capabilities of the other team, and thereby relinquish some of its own responsibility. Institutional provisions are needed to manage this conflict.The alleviation of this moral hazard entails a dilemma. Considerations of failure prevention and disaster recovery must be combined in the design process. The design teams must be aware of each other, and even collaborate, because a single coherent system must emerge. But we don't want either team to relinquish any responsibility. On the one hand we want the failure prevention team to work as though there is no disaster recovery, and the disaster recovery team should presume that failures will occur. On the other hand, we want these teams to collaborate on the design.This moral hazard and its dilemma do not obviate the need for both elements of the design. Fukushima has taught us an important lesson by highlighting the special challenge of high-risk critical technologies: design so failure cannot occur, and prepare to respond to the unanticipated. Full Article
rom Non-Profit Persuasion Lesson from Jay-Z By feeds.feedblitz.com Published On :: Tue, 19 Nov 2019 12:59:07 +0000 Rapper Jay-Z used a classic influence principle for non-profit persuasion. The post Non-Profit Persuasion Lesson from Jay-Z appeared first on Neuromarketing. Full Article Neuromarketing fundraising non-profit nonprofit personalization reciprocation reciprocity rolex
rom How Do You Help a Partner Who is Depressed? Advice From a Sex Therapist By feedproxy.google.com Published On :: Wed, 08 Apr 2020 14:00:00 +0000 Depression is one of the most common mental health issues in the United States. In fact, according to the National Institutes of Mental Health, 1 in 14 Americans experienced an episode of major depression in the last year alone. Given the circumstances surrounding the current COVID-19 coronavirus pandemic, many in the mental health community predict that the number will be even higher this year because these circumstances are creating a “perfect storm” of depression risks. The widespread prevalence of depression has a lot of implications for our lives, even if we don’t personally have depression ourselves. Many of us will have loved ones, such as a romantic partner, who develops depression at some point. In these situations, it’s common for people to wonder how they can help their partner most effectively. So what should they do? Full Article Videos
rom 5 Secrets to Increase Your Sexual Satisfaction: Tips From a Sex Therapist By feedproxy.google.com Published On :: Wed, 15 Apr 2020 14:00:00 +0000 As a practicing sex therapist, I often see two partners legitimately trying to bridge a satisfaction gap between each other, but they can’t seem to get the moves just right. If left unchecked, this can lead to resentment and conflict; however, couples who figure out how to speak to each other sexually (both verbally and nonverbally) have the highest success in terms of finding something that works for both of them. Making an environment conducive to this sort of positive growth requires a little bit of effort and the ability to listen. Drawing on my clinical experience, here are my top tips for increasing sexual satisfaction: Full Article Sexual Problems and Solutions
rom Have You Reached Out to or Heard From an Ex During the Pandemic? You're Not Alone By feedproxy.google.com Published On :: Wed, 06 May 2020 14:00:00 +0000 Anecdotally, I’ve heard from a lot of people who have said that they reached out to (or heard from) and ex-partner since the COVID-19 coronavirus pandemic began. But just how many people have done so? And what motivated them to reconnect? Some of my colleagues and I at The Kinsey Institute are currently in the midst of researching how this pandemic is affecting people’s intimate lives (click here if you’d like to participate and learn more about the study), and our preliminary data suggest that reaching out to an ex isn’t a rare occurrence. Full Article Relationships Research
rom The weird history of the "sex chromosomes" | Molly Webster By feedproxy.google.com Published On :: Mon, 23 Mar 2020 14:48:37 +0000 The common thinking on biological sex goes like this: females have two X chromosomes in their cells, while males have one X and one Y. In this myth-busting talk, science writer and podcaster Molly Webster shows why the so-called "sex chromosomes" are more complicated than this simple definition -- and reveals why we should think about them differently. Full Article Higher Education
rom What the world can learn from China's response to the coronavirus | Gary Liu By feedproxy.google.com Published On :: Fri, 27 Mar 2020 16:55:50 +0000 From Hong Kong, South China Morning Post CEO Gary Liu tracks China's response to the coronavirus pandemic -- from the initial outbreak in Wuhan to the shutdown of Hubei province and the containment measures taken across its major cities. Sharing insights into how the culture in places like Hong Kong and South Korea contributed to fast action against the virus, Liu identifies lessons people across the world can use to stop its spread. (This virtual conversation is part of the TED Connects series, hosted by head of TED Chris Anderson and current affairs curator Whitney Pennington Rodgers. Recorded March 25, 2020) Full Article Higher Education
rom What's missing from the American immigrant narrative | Elizabeth Camarillo Gutierrez By feedproxy.google.com Published On :: Tue, 21 Apr 2020 14:55:25 +0000 Recounting her story of finding opportunity and stability in the US, Elizabeth Camarillo Gutierrez examines the flaws in narratives that simplify and idealize the immigrant experience -- and shares hard-earned wisdom on the best way to help those around us. "Our world is one that flourishes when different voices come together," she says. Full Article Higher Education
rom Coronavirus Squeezes Supply of Chromebooks, iPads, and Other Digital Learning Devices By feedproxy.google.com Published On :: Wed, 01 Apr 2020 00:00:00 +0000 School districts are competing against each other for purchases of digital devices as remote learning expands to schools across the country. Full Article Massachusetts
rom Online Charter Schools in North Carolina Petition to Go From Pilot to Permanent By feedproxy.google.com Published On :: Tue, 21 Nov 2017 00:00:00 +0000 The state's two virtual charter schools have earned poor marks from the state's accountability system in the few years they've been operating. Full Article North_Carolina
rom Staff Email Addresses Removed From District Websites to Improve Cybersecurity By feedproxy.google.com Published On :: Wed, 05 Dec 2018 00:00:00 +0000 Some district technology leaders say having staff email addresses publicly available opens the door for phishing scams and potential hacks. Full Article Virginia
rom How Schools Will Overcome the 'Coronavirus Slide:' Ideas From 5 Superintendents By feedproxy.google.com Published On :: Tue, 07 Apr 2020 00:00:00 +0000 With many school buildings closed for the rest of the academic year—and more to follow—district leaders turn their attention to making up for what may be deep learning losses. Full Article Virginia
rom How Schools Will Overcome the 'Coronavirus Slide:' Ideas From 5 Superintendents By feedproxy.google.com Published On :: Tue, 07 Apr 2020 00:00:00 +0000 With many school buildings closed for the rest of the academic year—and more to follow—district leaders turn their attention to making up for what may be deep learning losses. Full Article Oklahoma
rom Gay teacher ousted from Catholic school after 23 years By feedproxy.google.com Published On :: 2020-05-04T22:56:59-04:00 Full Article Education
rom A New Worry From the COVID-19 Crisis: Paying for College By feedproxy.google.com Published On :: 2020-05-05T16:50:00-04:00 Fewer students are filing financial aid applications this year, as the pandemic continues to disrupt college plans for high school seniors nationwide. Full Article Education
rom Judge blocks Tennessee from implementing voucher program By feedproxy.google.com Published On :: 2020-05-07T22:46:34-04:00 Full Article Education
rom North Dakota, Wyoming Move Away From Smarter Balanced Tests By feedproxy.google.com Published On :: Tue, 03 May 2016 00:00:00 +0000 North Dakota and Wyoming state superintendents said this week that they will soon hire new testing vendors. Full Article North_Dakota
rom DeVos Visits Kentucky School Recovering From Shooting By feedproxy.google.com Published On :: Wed, 17 Apr 2019 00:00:00 +0000 U.S. Secretary of Education Betsy DeVos on Wednesday visited a Kentucky high school that is recovering from a 2018 shooting to award additional grant money meant to aid its recovery efforts. Full Article Kentucky
rom Teacher Activism Played Prominent Role in Southern Governors' Races By feedproxy.google.com Published On :: Wed, 06 Nov 2019 00:00:00 +0000 Governors' races in Kentucky and Mississippi took center stage, testing the political muscle of teacher activists and yielding possible policy implications for everything from public employee pensions to teacher pay. Full Article Kentucky
rom How Schools Will Overcome the 'Coronavirus Slide:' Ideas From 5 Superintendents By feedproxy.google.com Published On :: Tue, 07 Apr 2020 00:00:00 +0000 With many school buildings closed for the rest of the academic year—and more to follow—district leaders turn their attention to making up for what may be deep learning losses. Full Article Kentucky
rom Lessons From a 'Hidden Gem' in Alabama By feedproxy.google.com Published On :: Tue, 27 Sep 2016 00:00:00 +0000 A rural Southern school with a predominantly Native American population engages the whole community in its continued quest for improvement. Full Article Alabama
rom Rapid Deployment of Remote Learning: Lessons From 4 Districts By feedproxy.google.com Published On :: Thu, 19 Mar 2020 00:00:00 +0000 Chief technology officers are facing an unprecedented test of digital preparedness due to the coronavirus pandemic, struggling with shortfalls of available learning devices and huge Wi-Fi access challenges. Full Article Maryland
rom New York Takes Final Step to Separate State Test Scores From Teacher Evaluations By feedproxy.google.com Published On :: Thu, 24 Jan 2019 00:00:00 +0000 The New York state legislature passed a bill that would make the use of state test scores in these evaluations optional, leaving the decision up to districts and making it subject to collective bargaining. Full Article New_York
rom Prominent Literacy Expert Denies Dyslexia Exists; Says to 'Shoot' Whoever Wrote Law on It By feedproxy.google.com Published On :: Wed, 11 Dec 2019 00:00:00 +0000 A group of teachers and literacy advocates are pushing back after Richard Allington, one of the country's most prominent experts on early literacy, made inflammatory claims about dyslexia at a Tennessee literacy conference this week. Full Article Tennessee
rom Court Bars Tennessee From Starting School Voucher Program By feedproxy.google.com Published On :: Tue, 05 May 2020 00:00:00 +0000 A court said legislators violated the state's constitution when they passed a law that targeted specific areas to be included in the program without local consent. Full Article Tennessee
rom Judge blocks Tennessee from implementing voucher program By feedproxy.google.com Published On :: Fri, 08 May 2020 00:00:00 +0000 Full Article Tennessee
rom Gay teacher ousted from Catholic school after 23 years By feedproxy.google.com Published On :: 2020-05-05T08:38:08-04:00 Full Article Education
rom A New Worry From the COVID-19 Crisis: Paying for College By feedproxy.google.com Published On :: 2020-05-05T16:46:55-04:00 Fewer students are filing financial aid applications this year, as the pandemic continues to disrupt college plans for high school seniors nationwide. Full Article Education
rom Judge blocks Tennessee from implementing voucher program By feedproxy.google.com Published On :: 2020-05-08T08:50:39-04:00 Full Article Education
rom What This Superintendent Learns From Teaching a High School Course By feedproxy.google.com Published On :: Tue, 25 Feb 2020 00:00:00 +0000 The leader of a Montana school district spends up to two hours each day grading assignments from students in an online English credit recovery program. Full Article Montana
rom In Response to Federal Feedback, N.J. Seeks Testing Waiver From ESSA By feedproxy.google.com Published On :: Mon, 31 Jul 2017 00:00:00 +0000 The state wants to test its middle school students in the mathematics courses in which they're enrolled, rather than with the state tests created for that each student's particular grade. Full Article New_Jersey
rom How Schools Will Overcome the 'Coronavirus Slide:' Ideas From 5 Superintendents By feedproxy.google.com Published On :: Tue, 07 Apr 2020 00:00:00 +0000 With many school buildings closed for the rest of the academic year—and more to follow—district leaders turn their attention to making up for what may be deep learning losses. Full Article New_Jersey
rom Utah Will Ask for Test Participation Waiver From ESSA By feedproxy.google.com Published On :: Fri, 09 Feb 2018 00:00:00 +0000 Utah's state board members said last week that they support its state's test participation law which conflicts with the Every Student Succeeds Act. Full Article Utah
rom Hacked and Cut Off From the Public: This Is School Board Business in the Coronavirus Crisis By feedproxy.google.com Published On :: Wed, 08 Apr 2020 00:00:00 +0000 Social distancing is forcing school business to be conducted virtually, putting school boards in the difficult spot of making crucial decisions on spending and other issues without the same level of public input. Full Article Pennsylvania
rom Rhode Island to Promote Blended Learning Through Nonprofit Partnership By feedproxy.google.com Published On :: Fri, 08 Aug 2014 00:00:00 +0000 The Rhode Island Department of Education and the nonprofit Learning Accelerator are teaming to develop a strategic plan and a communications strategy aimed at expanding blended learning. Full Article Rhode_Island
rom Rapid Deployment of Remote Learning: Lessons From 4 Districts By feedproxy.google.com Published On :: Thu, 19 Mar 2020 00:00:00 +0000 Chief technology officers are facing an unprecedented test of digital preparedness due to the coronavirus pandemic, struggling with shortfalls of available learning devices and huge Wi-Fi access challenges. Full Article Oregon
rom Oregon State lands big commitment from 4-star ILB Easton Mascarenas By sports.yahoo.com Published On :: Wed, 06 May 2020 00:53:38 GMT Coach Smith is doing a fine job Building the Dam Full Article article Sports
rom Jets sign Lamar Jackson (the undrafted DB from Nebraska) By sports.yahoo.com Published On :: Wed, 06 May 2020 21:40:59 GMT The Jets announced on Wednesday that they have signed Lamar Jackson, but no one start frantically wondering what they missed regarding the 2019 NFL MVP. The Lamar Jackson that the Jets signed is an undrafted defensive back from Nebraska rather than the Ravens quarterback. The Jets' Jackson was second-team All-Big Ten last season after recording [more] Full Article article Sports
rom Why Oregon Football is one year away from winning a College Football Playoff By sports.yahoo.com Published On :: Thu, 07 May 2020 22:42:01 GMT Geoff Schwartz joins the latest Talkin' Ducks Podcast with host Jordan Kent Full Article article Sports
rom Seeking Their Due From Court Ruling, Washington State Teachers Strike By feedproxy.google.com Published On :: Tue, 04 Sep 2018 00:00:00 +0000 Classrooms across Washington state sat empty last week, as teachers in seven districts went on strike when negotiations over salaries and benefits failed to result in contracts by the first day of school. Full Article Washington
rom Just a girl from Crewe / Janice Madden. By www.catalog.slsa.sa.gov.au Published On :: Full Article
rom To make terms of compromise a rule of Court or not? That is the question : an analysis of the options available to settle estate matters / presended by Christina Flourentzou, Supreme Court of South Australia.. By www.catalog.slsa.sa.gov.au Published On :: Full Article
rom Inferring Express Trusts from Inexplicit Contracts. By www.catalog.slsa.sa.gov.au Published On :: Full Article
rom Social Media and Promoting Your Law Practice. By www.catalog.slsa.sa.gov.au Published On :: Full Article