Mruk, Christopher J

Pickover, Clifford A

Badger, Michael

Sawyer, R. Keith (Robert Keith)

Nyathi, Pathisa, 1951-

Khan, Shahnaz

Ehrlich, Walter, 1921-

Amit-Cohen, Irit

Rotenstreich, Nathan, 1914-1993

Bardin, Hillel

This cohort study compares the characteristics and management of acute heart failure in global regions comprising 44 countries.

This prespecified secondary analysis of the MOMENTUM 3 randomized clinical trial aims to determine whether clinical outcomes of patients with 2 different left ventricular assist devices differed based on preoperative categories of bridge to transplant/bridge to candidacy vs destination therapy.

This study develops and validates a quantitative method to predict the pulmonary to systemic flow ratio in patients with congenital heart disease from chest radiographs using deep learning.

This cohort study assesses whether long-term variability and rate of change of blood pressure from young adulthood to midlife are associated with cardiovascular disease and all-cause mortality by middle age.

Increased attention has focused on shared decision-making (SDM) and use of decision aids for treatment decisions in cardiology. In this issue of JAMA Cardiology, Coylewright et al report the results of a rigorously performed pilot study on the use of a decision aid to facilitate SDM for patients with symptomatic severe aortic stenosis (AS) at high or prohibitive risk for surgery considered for transcatheter aortic valve replacement vs medical therapy. Comparisons were made between encounters before clinicians were trained to use a decision aid and the first and fifth encounters after a decision aid was used. The patient-clinician interactions were audio recorded and later coded by independent reviewers using a validated measure to assess SDM. This mixed-methods study found that SDM significantly improved in a stepwise manner from the initial usual care encounter (before use of a decision aid) to the first and then fifth encounters after implementation of the decision aid. Along with this improvement in SDM, patients (n = 35) demonstrated increased knowledge about their treatment choices and reported increased satisfaction in their care with no increase in decisional conflict. In contrast, clinicians (n = 6) reported that they believed they already engaged in SDM prior to use of the decision aid and, after multiple uses of the decision aid, believed patients did not understand or benefit from this tool. The disconnect between clinician and patient perspectives was sobering and has implications for the adoption of decision aids or other tools to facilitate SDM in the clinical setting. Notable limitations of the study, which are acknowledged by the authors, include (1) small sample size (of clinicians and patients); (2) the decision aid is most useful for the relatively smaller number of patients at high or prohibitive risk for surgery for whom transcatheter aortic valve replacement and medical therapy may both be reasonable options; and (3) the lack of diversity in the clinicians (all male), which reflects the current demographics of interventional cardiology and cardiac surgery.

This mixed-methods pilot study examines whether the repeated use of a decision aid by heart teams was associated with greater shared decision-making, along with improved patient-centered outcomes and clinicians’ attitudes about decision aids.

Lowering low-density lipoprotein cholesterol (LDL-C) levels remains a mainstay of cardiovascular disease prevention, but gaps in treatment remain, even in persons with hypercholesterolemia and greatly elevated LDL-C levels. Although well-described gene variants in the apolipoprotein B (APOB), low-density lipoprotein receptor (LDLR), and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes explain small but important fractions of monogenic hypercholesterolemia, recent attention has turned to prognostication of cardiovascular disease using polygenic risk scores (PRS) that incorporate common genetic variants derived from large-scale genome-wide association studies of lipid subfractions. Earlier PRS considered only variants with genome-wide significance, and newer studies have focused on methods that better capture the variance conferred by millions of variants, suggesting an ability to identify risk equivalent to monogenic mutations. There remains a gap in evidence from prospective observational studies or treatment trials regarding the appropriate placement of PRS in risk assessment and lipid treatment decisions relative to information on rare monogenic gene variants, particularly in multiethnic populations.

This cohort study uses the UK Biobank cohort data to compare the association of monogenic vs polygenic hypercholesterolemia with the risk of atherosclerotic cardiovascular disease among individuals with comparable levels of low-density lipoprotein cholesterol.

Secondary mitral regurgitation (MR) has long been recognized as prognostically important. Even mild MR is associated with adverse outcomes. Yet, surgical trials have not shown improved survival with invasive therapy whereas medical therapy and cardiac resynchronization therapy are associated with improved outcomes. The 2018 publication of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) and Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR) trials and their apparently discordant results have focused attention on the differences in trial design as well as patient populations.

This Special Communication proposes a classification of patients with left-ventricular disease according to the severity of mitral regurgitation that is proportionate vs disproportionate to left-ventricular end-diastolic volume.

With a date span of 1779 through 1955, the McManus-Young Collection provides a rich survey of the literature of "illusion practices," which includes works on conjuring, ventriloquism, fortune-telling, spiritualism, witchcraft, gambling, hypnotism, automata, and mind reading comprised of a gathering of thousands of pamphlets and offprints. This ephemeral literature is the backbone of modern...

Latin jazz musician and band leader Machito (circa 1908-1984) was active on the New York City jazz scene with his innovative band the Afro-Cubans from 1940 to the early 1980s, forming an influential legacy that includes salsa music and Afro-Cuban jazz. The collection contains approximately 150 manuscript and published compositions and arrangements performed by the ensemble, as well as clippings,...

Lawyer, educator, and judge. Personal and official correspondence, lectures, legal briefs and opinions, legal case files, memoranda, speeches, writings, research notes, and other papers documenting Bork's career as a lawyer, legal scholar, professor of law, and federal appellate court judge. Also included is material relating to his unsuccessful nomination to the Supreme Court.

Economist, government official, and director of the Congressional Budget Office. Correspondence, memoranda, reports, speeches and other writings, congressional testimony, printed materials, newspaper clippings, and photographs pertaining to Rivlin's career as an economist and government official.

Associate justice of the United States Supreme Court. Correspondence and telegrams, some written while Lurton was attending the University of Chicago (1857-1886) and while he was a prisoner in Camp Chase, Ohio, and at Johnson Island Prison during the Civil War.

Sculptor and artist. Correspondence, writings, financial records, scrapbooks, newspaper clippings, photographs, and other papers of French, his daughter, Margaret French Cresson, and other members of the French family relating primarily to French's career as a sculptor and artist and to the French family.

Lawyer, army officer, United States representative from California, United States commissioner of Indian affairs, and governor of Kansas. Letterpress books containing correspondence relating to Denver's law practice in Washington, D.C., which was concerned with Choctaw Indian claims and land disputes in California and elsewhere in the West; his campaign for the Democratic presidential...

Novelist and author. Correspondence, diaries, drafts and galleys of playscripts, poems, songs, and fiction and nonfiction books, tearsheets, dictation and interview transcripts, notes, research materials, descriptive inventories of personal papers, legal and financial documents, clippings, printed material, scrapbooks, publicity and promotional records, maps, book illustrations, photographs, and...

Barker Library - PQ7298.422.U37 L67 2019

Dewey Library - PQ6653.E62 M6613 2020

Hayden Library - PQ7296.J6 Z8928 2018

Dewey Library - PQ7390.G773 D6613 2018

Dewey Library - PQ7070.C65 2018

The Congress manifesto is the polar opposite of policies pursued by UPA-II. It promises to undo measures that clogged the economy and make economic growth the "overriding priority".

Lacking a cohesive national campaign, Kejriwal has yet again taken recourse to insurgent tactics – projecting himself as Modi’s only rival when Congress is yet to declare its nominee for Varanasi.

The disappearance of inflammatory communal slogans from political speeches suggests development is the agenda for 2014.

As polls come closer arrows are flying thicker, faster, sharper. Some are of time-honoured design, others quite modern. Included in the first category is flaming a party leader as communal or dissing her for being in the Italians’ pocket.

By fielding one of its vice-presidents – former television soap star Smriti Irani – against Congress’s Rahul Gandhi in Amethi Lok Sabha constituency, BJP has shown it is inclined to take the electoral battle to one of two Gandhi pocket boroughs in Uttar Pradesh.

On the face of it the Fifa World Cup is all about quality football, generally recognised as the greatest sporting showpiece on earth.

Going by a letter written by Nawaz Sharif to Narendra Modi, that he was 'much satisfied' with their meeting in New Delhi, the two prime ministers have succeeded in striking up a working relationship.