16,000 square kilometers of giant panda habitat will likely be lost by the year 2080

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In celebration of the annual spring appearance of the Easter bunny on Sunday, April 8, Smithsonian Science offers these five facts from the book "Rabbits: The Animal Answer Guide"

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To celebrate the 10th anniversary of researchers producing the first complete human genome sequence — the genetic blueprint of the human body — the Smithsonian’s National Museum of Natural History, will open a new high-tech, high-intensity exhibition in 2013.

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The discovery of the first transiting circumbinary multi-planet system: two planets orbiting around a pair of stars, is announced by astronomers.

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Frontispiece illustration of “flies” from the 1882 book American game fishes, their habits, habitat, and peculiarities; how, when, and where to angle for them, featuring […]

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Among vertebrates few animals rival poison dart frogs for their vibrant electric blue, yellow, red and orange skin colors. Some experts have long believed these […]

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In our solar system, only one planet is blessed with an ocean: Earth. Our home world is a rare, blue jewel compared to the deserts […]

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                  The Smithsonian Libraries will open its new exhibition “Whales: From Bone to Book” in the Smithsonian’s National Museum […]

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Wetlands Wetlands are one of the habitats to benefit most from conservation. The North American Wetlands Conservation Act has enabled strategic conservation projects covering a […]

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Among the bats, rats and other ferocious animals that lie within the storage drawers of the mammal collection in the Smithsonian’s National Museum of Natural […]

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Point your smartphone at the skeleton of a vampire bat mounted in a museum case, wait a minute and you will see it wiggle, jump […]

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A bite mark on a homicide victim’s skin is not an unusual discovery. A criminal’s teeth marks are also occasionally found on food at a […]

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Finding clean ways to store water is a challenge that humans have faced for millennia. In a new paper in Environmental Health, anthropologist Sabrina Sholts […]

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Two separate teams of scientists have identified major challenges for the development of life in what has recently become one of the most famous exoplanet […]

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Some of the earliest humans to inhabit America came from Europe according to a new book "Across Atlantic Ice: The Origin of America's Clovis Culture."

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For the first time in its history the Smithsonian’s National Museum of African Art opened an exhibition on the continent of Africa. “Chief S.O. Alonge: […]

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Stephen Kershaw, David J. Morgan, James Boyd, David G. Spiller, Gareth Kitchen, Egor Zindy, Mudassar Iqbal, Magnus Rattray, Chris M. Sanderson, Andrew Brass, Claus Jorgensen, Tracy Hussell, Laura C. Matthews, and David W. Ray

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR) to regulate immunity, energy metabolism, and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcription. We show GCs rapidly inhibit cell migration, in response to both GR agonist and antagonist ligand binding. The inhibitory effect on migration is prevented by GR knockdown with siRNA, confirming GR specificity, but not by actinomycin D treatment, suggesting a non-transcriptional mechanism. We identified a rapid onset increase in microtubule polymerisation following glucocorticoid treatment, identifying cytoskeletal stabilisation as the likely mechanism of action. HDAC6 overexpression, but not knockdown of αTAT1, rescued the GC effect, implicating HDAC6 as the GR effector. Consistent with this hypothesis, ligand-dependent cytoplasmic interaction between GR and HDAC6 was demonstrated by quantitative imaging. Taken together, we propose that activated GR inhibits HDAC6 function and thereby increases the stability of the microtubule network to reduce cell motility. We therefore report a novel, non-transcriptional mechanism whereby GCs impair cell motility through inhibition of HDAC6 and rapid reorganization of the cell architecture.

Admired from afar by the ancient Romans, the moon was once deified as a goddess, Luna. Today, two-thousand years later, geologists who scrutinize the moon’s […]

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Have an upset stomach? Pop a chalky, chewable antacid. Maybe you’ve got a painful cut or burn. No problem; reach for a healing ointment or […]

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The three male cheetahs that left the Zoo's D.C. campus in 2009 returned in November and are now on exhibit. The five-and-a-half-year-old brothers―Draco, Granger, and Zabini, named after characters in the Harry Potter stories―have been living at the Zoo's Smithsonian Conservation Biology Institute's Cheetah Science Facility in Front Royal, Virginia.

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The post “How Soil Savvy are You?, is featured in the exhibition “Dig It! The Secrets of Soil,” from the Smithsonian Traveling Exhibition Service appeared first on Smithsonian Insider.

This new PBS Newshour video takes a look at a new exhibit at the Air and Space Museum celebrating NASA's space art program.

The post PBS Newshour takes a look at the new National Air and Space Museum exhibition “NASA | ART: 50 Years of Exploration” appeared first on Smithsonian Insider.

The moon passed between the Earth and the sun on Thursday, Oct. 23. While avid stargazers in North America looked up to watch the spectacle, the […]

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How 3D technology is used at the Smithsonian to create world class exhibits!

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Get a look behind the scenes as we installed “Outside the Spacecraft: 50 Years of Extra-vehicular Activity,” a new exhibition on view at the Museum […]

The post “Outside the Spacecraft,” a new exhibition at the Air and Space Museum appeared first on Smithsonian Insider.

Yellow lady’s slippers, watercolor by Kathleen Garness, from the National Museum of Natural History exhibit “Losing Paradise? Endangered Plants Here and Around the World,” opening […]

The post Exhibition: Endangered plants here and around the world appeared first on Smithsonian Insider.

Physical quantities in arbitrary dimensional space can be classified into 41 types using three antisymmetries within the framework of Clifford algebra.

Full Text:

A new study shows that graphene sheets can block the signals mosquitoes use to identify a blood meal, potentially enabling a new chemical-free approach to mosquito bite prevention. Researchers showed that multilayer graphene can provide a twofold defense against mosquito bites. The ultra-thin yet strong material acts as a barrier that mosquitoes are unable to bite through. At the same time, experiments showed that graphene also blocks chemical signals mosquitoes use to sense that a blood meal is near, blunting their urge to bite in the first place. The findings suggest that clothing with a graphene lining could be an effective mosquito barrier.

Image credit: Hurt Lab/Brown University

Source: Streetwise Reports   05/07/2020

In a May 5 research note, analyst John Freeman reported that Raymond James increased its target price on Parsley Energy, Inc. (PE:NYSE) after it posted its Q1/20 numbers.

Raymond James' new target price on Parsley is $12 per share, up from $11. The Texas-based energy company's stock is trading now at about $9.38 per share.

Freeman reviewed and commented on Parsley's Q1/20 results. The company "delivered modest EBITDA and earnings per share beats relative to the Street" due to oil pricing," Freeman pointed out.

Production was relatively in line at 126,600,000 barrels of oil per day (126.6 MMbbl/d), which was 1% higher than consensus' forecast but 1% below Raymond James' estimate. Total production was 1% above the Street's projection but 3% below Raymond James' forecast.

"The performance on the quarter was encouraging, however, the highlight from earnings was the significant reduction in 2020 capex (down from about $1 billion to less than $700 million)," Freeman commented.

Capex, "a welcome surprise," Freeman wrote, came in 5% and 7% lower than the investment bank and the Street's estimates, respectively. Opex was 3% under Raymond James' projection

Moreover, Parsley's related maintenance capital needs were greatly below expectations as well, indicating that Parsley made capital efficiency gains during the period.

"We were pleasantly surprised that Parsley is able to maintain in line Q4/20 oil volumes (about 115 MMbbl/d) on a capital program that's about $300 million/30% below the Street," added Freeman.

Looking forward, Raymond James modeled a base case, or stable scenario for Parsley, that implies a West Texas Intermediate oil price of about $30 a barrel and Parsley having four to five rigs and one to two crews operating. In that scenario, Parsley would produce about 117 MMbbl/d in 2020 and 115 MMbbl/d in 2021.

Capex would amount to about $678 million in 2020, dropping to $598 million in 2021.

Free cash flow would be about $300 million in 2020, which coincides with Parsley's guidance of $300M plus, and increasing to $370 million in 2021.

Raymond James has an Outperform rating on Parsley Energy.

Disclosure:
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Disclosures from Raymond James, Parsley Energy Inc, May 5, 2020

ANALYST INFORMATION

Analysts Holdings and Compensation: Equity analysts and their staffs at Raymond James are compensated based on a salary and bonus system. Several factors enter into the bonus determination, including quality and performance of research product, the analyst's success in rating stocks versus an industry index, and support effectiveness to trading and the retail and institutional sales forces. Other factors may include but are not limited to: overall ratings from internal (other than investment banking) or external parties and the general productivity and revenue generated in covered stocks.

The analyst John Freeman, primarily responsible for the preparation of this research report, attests to the following: (1) that the views and opinions rendered in this research report reflect his or her personal views about the subject companies or issuers and (2) that no part of the research analyst's compensation was, is, or will be directly or indirectly related to the specific recommendations or views in this research report. In addition, said analyst(s) has not received compensation from any subject company in the last 12 months.

RAYMOND JAMES RELATIONSHIP DISCLOSURES
Certain affiliates of the RJ Group expect to receive or intend to seek compensation for investment banking services from all companies under research coverage within the next three months.

Raymond James & Associates, Inc. makes a market in the shares of Parsley Energy, Inc.

Additional Risk and Disclosure information, as well as more information on the Raymond James rating system and suitability categories, is available here.