ALEXANDRA SHULMAN: How much are you really drinking in these lockdown days? Studies claim that one person in three is drinking less often that causal, but I can't say I've come across them.

Sabina Vankov's decision to return to her homeland with their daughter Angelina came a month after the MoS revealed she had asked Mr Opik to move out. She is pregnant with his child.

The Good Morning Britain presenter has previously accused the Duchess of Sussex of having 'ditched' her own relatives and splitting her husband Prince Harry from the Royal Family.

2. Notice issued shall indicate that reply shall be filed within two days of the receipt of notice.

List on 27th April 2020.

(RAJNESH OSWAL) (GITA MITTAL) JUDGE CHIEF JUSTICE Jammu 23.04.2020 Raj Kumar RAJ KUMAR 2020.04.23 15:38 I attest to the accuracy and integrity of this document

Issue notice of this application to the respondents. Mr. Amit Gupta, AAG accepts notice.

2 WP(C) PIL NO. 41/2019 Let a copy of this application be sent to Mr. Amit Gupta, AAG by Mrs. Deepika Mahajan, Advocate, who shall seek instructions that immediate steps are taken to ensure food and all facilities to these survival of natural calamity.

Let a copy of this application be also furnished to Mr. M. K. Sharma, Member Secretary, State Legal Services Authority, Jammu and Ms. Sandeep Kour, Secretary, District Legal Services Authority, Udhampur to ensure that these people are given immediate assistance.

Bagpipes, tartan, thistles and lochs - such things are the basis of Scotland's tourist industry. And, to some extent, Scotland's national identity too.

ALEXANDRA SHULMAN: How much are you really drinking in these lockdown days? Studies claim that one person in three is drinking less often that causal, but I can't say I've come across them.

Sabina Vankov's decision to return to her homeland with their daughter Angelina came a month after the MoS revealed she had asked Mr Opik to move out. She is pregnant with his child.

Newport defender Ryan Inniss has been hit with a five-game ban for biting. The centre-back received his punishment after being sent off following an off-the-ball clash against West Ham's under-21s.

This Tuesday, the Bitcoin is expected to undergo a 'halving'. Will it offer a new opportunity for investors to make a profit? Or as legendary investor Warren Buffett believes, is it no more than 'rat poison'?

Hudgens then served '60s in another look, sporting a sleeveless white turtleneck, a black headband and gold jewelry, writing: 'Then moved to a Brigitte Bardot vibe lol.'

Fabio Cannavaro is currently in his second spell at Chinese Super League club Guangzhou Evergrande. However the retired defender has ambitions to one day manage in England.

One of the unprepared-for aspects of the continuing lockdown was the 40-day prohibition of over-the-counter sale of alcohol. To complain about its unavailability while people are fighting for lives and livelihoods would be, at best,...

This is probably the book that twihards have been waiting for.

Fitness tracking wearables maker Fitbit recently launched its Charge 2 and Flex 2 fitness trackers in India. While the Flex 2 is priced at Rs 9,499, the more expensive Charge 2 bears a price tag of Rs 14,999. The new Fitbit Charge 2 has a heart-rate monitor, a feature previously limited to the 'HR' edition of the Charge only. It comes with a touch-sensitive OLED display, as well as a 3-axis accelerometer, an altimeter and a vibration motor. Fitbit Charge 2 syncs with its companion smartphone app over Bluetooth.

Jibit George, the young filmmaker who made his directorial debut with the recent movie Kozhipporu, passed away. The 31-year-old breathed his last due to cardiac arrest on May 9, 2020 evening. According to the reports, Jibit George was suffering from chest

Jibit George, the young filmmaker who made his directorial debut with the recent movie Kozhipporu, passed away. The 31-year-old breathed his last due to cardiac arrest on May 9, 2020 evening. According to the reports, Jibit George was suffering from chest

Daniel Ricciardo cannot wait for Formula One to get back to racing in a COVID-19 blighted season, and when it does he reckons the first grand prix could be a recipe for chaos.

Archives, Room Use Only - T960.E1 U68 1876

Archives, Room Use Only - HE7045.C46 1952

Sunita Williams chose an off-beat career and touched the skies.

Autor:
Erschienen
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URN: urn:nbn:de:bvb:12-bsb00131315-7
URL: http://daten.digitale-sammlungen.de/~db/0013/bsb00131315/images/

Fast trashion: Exhibition of garments made from street-litter opens at Imperial | Imperial News  Imperial College London

In the title compound, C27H30N4O6·H2O, the two dioxolo rings are in envelope conformations, while the pyran ring is in a twisted-boat conformation. The pyradizine ring is oriented at dihedral angles of 9.23 (6) and 12.98 (9)° with respect to the pyridine rings, while the dihedral angle between the two pyridine rings is 13.45 (10)°. In the crystal, O—Hwater⋯Opyran, O—Hwater⋯Ometh­oxy­meth­yl and O—Hwater⋯Npyridazine hydrogen bonds link the mol­ecules into chains along [010]. In addition, weak C—Hdioxolo⋯Odioxolo hydrogen bonds and a weak C—Hmeth­oxy­meth­yl⋯π inter­action complete the three-dimensional structure. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H⋯H (55.7%), H⋯C/C⋯H (14.6%), H⋯O/O⋯H (14.5%) and H⋯N/N⋯H (9.6%) inter­actions. Hydrogen-bonding and van der Waals inter­actions are the dominant inter­actions in the crystal packing. Electrochemical measurements are also reported.

Two compounds, 1,3-diethyl-5-{(2E,4E)-6-[(E)-1,3,3-tri­methyl­indolin-2-yl­idene]hexa-2,4-dien-1-yl­idene}pyrimidine-2,4,6(1H,3H,5H)-trione or TMI, C25H29N3O3, and 1,3-diethyl-2-sulfanyl­idene-5-[2-(1,3,3-tri­methyl­indolin-2-yl­idene)ethyl­idene]di­hydro­pyrimidine-4,6(1H,5H)-dione or DTB, C21H25N3O2S, have been crystallized and studied. These compounds contain the same indole derivative donor group and differ in their acceptor groups (in TMI it contains oxygen in the para position, and in DTB sulfur) and the length of the π-bridge. In both materials, mol­ecules are packed in a herringbone manner with differences in the twist and fold angles. In both structures, the mol­ecules are connected by weak C—H⋯O and/or C—H⋯S bonds.

The title compound, C15H22N4O5S, was prepared via alkyl­ation of 3-(chloro­meth­yl)-5-(pentan-3-yl)-1,2,4-oxa­diazole in anhydrous dioxane in the presence of tri­ethyl­amine. The thia­diazine ring has an envelope conformation with the S atom displaced by 0.4883 (6) Å from the mean plane through the other five atoms. The planar 1,2,4-oxa­diazole ring is inclined to the mean plane of the thia­diazine ring by 77.45 (11)°. In the crystal, mol­ecules are linked by C—H⋯N hydrogen bonds, forming chains propagating along the b-axis direction. Hirshfeld surface analysis and two-dimensional fingerprint plots have been used to analyse the inter­molecular contacts present in the crystal. Mol­ecular docking studies were use to evaluate the title compound as a potential system that inter­acts effectively with the capsid of the Hepatitis B virus (HBV), supported by an experimental in vitro HBV replication model.

The title compound, C24H18FNO3, crystallizes in the monoclinic centrosymmetric space group P21/n and its mol­ecular conformation is stabilized via C—H⋯O intra­molecular inter­actions. The supra­molecular network mainly comprises C—H⋯O, C—H⋯F and C—H⋯π inter­actions, which contribute towards the formation of the crystal structure. The different inter­molecular inter­actions have been further analysed via Hirshfeld surface analysis and fingerprint plots.

In the fused ring system of the title compound, C32H37NO4, the central di­hydro­pyridine ring adopts a flattened boat conformation, the mean and maximum deviations of the di­hydro­pyridine ring being 0.1429 (2) and 0.2621 (2) Å, respectively. The two cyclo­hexenone rings adopt envelope conformations with the tetra­substituted C atoms as flap atoms. The benzene and phenyl rings form dihedral angles of 85.81 (2) and 88.90 (2)°, respectively, with the mean plane of the di­hydro­pyridine ring. In the crystal, mol­ecules are linked via an O—H⋯O hydrogen bond, forming a helical chain along the b-axis direction. A Hirshfeld surface analysis indicates that the most important contributions to the crystal packing are from H⋯H (65.2%), O⋯H/H⋯O (18.8%) and C⋯H/H⋯C (13.9%) contacts. Quantum chemical calculations for the frontier mol­ecular orbitals were undertake to determine the chemical reactivity of the title compound.

The present work reports on the charge and spin density modelling of YTiO3 in its ferromagnetic state (TC = 27 K). Accurate polarized neutron diffraction and high-resolution X-ray diffraction (XRD) experiments were carried out on a single crystal at the ORPHÉE reactor (LLB) and SPRING8 synchrotron source. The experimental data are modelled by the spin resolved pseudo-atomic multipolar model (Deutsch et al., 2012). The refinement strategy is discussed and the result of this electron density modelling is compared with that from XRD measured at 100 K and with density functional theory calculations. The results show that the spin and charge densities around the Ti atom have lobes directed away from the O atoms, confirming the filling of the t2g orbitals of the Ti atom. The dxy orbital is less populated than dxz and dyz, which is a sign of a partial lift of degeneracy of the t2g orbitals. This study confirms the orbital ordering at low temperature (20 K), which is already present in the paramagnetic state above the ferromagnetic transition (100 K).

The X-chromosome-linked inhibitor of apoptosis protein (XIAP) is a multidomain protein whose main function is to block apoptosis by caspase inhibition. XIAP is also involved in other signalling pathways, including NF-κB activation and copper homeostasis. XIAP is overexpressed in tumours, potentiating cell survival and resistance to chemotherapeutics, and has therefore become an important target for the treatment of malignancy. Despite the fact that the structure of each single domain is known, the conformation of the full-length protein has never been determined. Here, the first structural model of the full-length XIAP dimer, determined by an integrated approach using nuclear magnetic resonance, small-angle X-ray scattering and electron paramagnetic resonance data, is presented. It is shown that XIAP adopts a compact and relatively rigid conformation, implying that the spatial arrangement of its domains must be taken into account when studying the interactions with its physiological partners and in developing effective inhibitors.

Co-crystallization is a phenomenon widely employed to enhance the physio-chemical and biological properties of active pharmaceutical ingredients (APIs). Exemestane, or 6-methyl­ideneandrosta-1,4-diene-3,17-dione, is an anabolic steroid used as an irreversible steroidal aromatase inhibitor, which is in clinical use to treat breast cancer. The present study deals with the synthesis of co-crystals of exemestane with thio­urea by liquid-assisted grinding. The purity and homogeneity of the exemestane–thio­urea (1:1) co-crystal were confirmed by single-crystal X-ray diffraction followed by thermal stability analysis on the basis of differential scanning calorimetry and thermogravimetric analysis. Detailed geometric analysis of the co-crystal demonstrated that a 1:1 co-crystal stoichiometry is sustained by N—H⋯O hydrogen bonding between the amine (NH2) groups of thio­urea and the carbonyl group of exemestane. The synthesized co-crystal exhibited potent urease inhibition activity in vitro (IC50 = 3.86 ± 0.31 µg ml−1) compared with the API (exemestane), which was found to be inactive, and the co-former (thio­urea) (IC50 = 21.0 ± 1.25 µg ml−1), which is also an established tested standard for urease inhibition assays in vitro. The promising results of the present study highlight the significance of co-crystallization as a crystal engineering tool to improve the efficacy of pharmaceutical ingredients. Furthermore, the role of various hydrogen bonds in the crystal stability is successfully analysed quantitatively using Hirshfeld surface analysis.

Invasive species, contaminants, excessive nutrient's and sediment are just some of the many factors threatening sensitive wetlands and seagrass beds.

The post Smithsonian to lead study on degradation of nearshore coastal habitats of the Chesapeake appeared first on Smithsonian Insider.

The stars move quickly because they are very close to each other, separated by only about one-fourth the distance from the Earth to the Moon. As a result, they share strong gravitational forces. They were once farther apart but have spiraled closer together over time. Billions of years from now, they will crash together and merge.

The post At 1,500,000 mph, twin stars in the constellation Cancer win speediest orbit award appeared first on Smithsonian Insider.

The Smithsonian’s National Zoo celebrated the completion of Phase I of Elephant Trails, an innovative and expanded home for Asian elephants, on Sept. 2. Phase […]

The post Elephant Trails exhibition opens at National Zoological Park appeared first on Smithsonian Insider.

This circa 1910 Yup'ik mask from Good News Bay, Alaska--made of driftwood, baleen, feathers, paint and cotton twine--is part of "Infinity of Nations: Art and History in the Collections of the National Museum of the American Indian," an exhibition at the National Museum of the American Indian, opening Saturday, Oct. 23.

The post Yup’ik mask in “Infinity of Nations” exhibition at the American Indian Museum appeared first on Smithsonian Insider.

Subjects watched demonstrators for varying amounts of time. When given the pipe, each of the subjects in both groups opened the door on their first attempt using the method they had seen demonstrated.

The post Lemurs exhibit ability for social learning in zoo experiment appeared first on Smithsonian Insider.

Last week, the Kepler team and CfA astronomers announced the discovery of a system of six transiting planets around one Sun-like star. The previous record holder for the number of transiting planets was three.

The post Six orbiting planets sets record for Sun-like stars say Kepler, Smithsonian astronmers appeared first on Smithsonian Insider.

The April 5 exhibits, “In the Mummy’s Tomb,” “Making a Mummy” and “What’s in a Face,” focus on Egyptian burial rites.

The post Mummies featured in new Smithsonian exhibition appeared first on Smithsonian Insider.

The National Aeronautics and Space Administration has made available to the public a new online collection of images that capture the excitement of planetary exploration and the journey to understand the origin and evolution of the solar system.

The post Stunning high-resolution NASA images available online for public exhibits appeared first on Smithsonian Insider.

Depending on where the fish disperse from, the use of ‘stepping stones', flotsam or simply being an adult can help in the journey to find a new home.

The post Ability to raft with flotsam and use non-reef habitats helps tropical fish journey to new places, study finds appeared first on Smithsonian Insider.

Astronomers using NASA's Kepler mission have detected two Earth-sized planets orbiting a distant star. This discovery marks a milestone in the hunt for alien worlds, since it brings scientists one step closer to their ultimate goal of finding a twin Earth.

The post Two Earth-sized planets discovered orbiting a distant Sun-like star appeared first on Smithsonian Insider.

"X-Ray Vision: Fish Inside Out," is a new exhibition of striking x-rays that reveal the complex bone structure of fishes in the collections of the Smithsonian's National Museum of Natural History.

The post New exhibition looks at fishes from the “Inside Out” appeared first on Smithsonian Insider.