gen QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism By feeds.nature.com Published On :: 2020-05-07 Full Article
gen NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
gen Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs By feeds.nature.com Published On :: 2014-12-18 miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors. Full Article
gen Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4 By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines. Full Article
gen Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
gen Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
gen Genocea's mark on malaria By feeds.nature.com Published On :: 2014-12-18 Genocea has identified an immunological imprint in patients with malaria and is using a $1.2 million grant from the Gates Foundation to turn the findings into a vaccine. Full Article
gen FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome By feeds.nature.com Published On :: 2020-05-04 Full Article
gen MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
gen Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
gen Machine intelligence lights up imaging By feeds.nature.com Published On :: 2020-04-28 Full Article
gen Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy By feeds.nature.com Published On :: 2020-04-21 Full Article
gen Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
gen New insights into K<sub>ATP</sub> channel gene mutations and neonatal diabetes mellitus By feeds.nature.com Published On :: 2020-05-06 Full Article
gen Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder By feeds.nature.com Published On :: 2020-05-04 Full Article
gen Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human By feeds.nature.com Published On :: 2020-04-28 Full Article
gen Efficient generation of mouse models with the prime editing system By feeds.nature.com Published On :: 2020-04-28 Full Article
gen Mendelian neurodegenerative disease genes involved in autophagy By feeds.nature.com Published On :: 2020-05-05 Full Article
gen Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors By feeds.nature.com Published On :: 2020-05-04 Full Article
gen Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea By feeds.nature.com Published On :: 2020-05-05 Full Article
gen An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders By feeds.nature.com Published On :: 2020-04-22 Full Article
gen Monogenic small vessel diseases — rare but still important By feeds.nature.com Published On :: 2020-04-30 Full Article
gen Generational trends in US opioid-overdose deaths By feeds.nature.com Published On :: 2020-05-04 Full Article
gen Age and generational patterns of overdose death risk from opioids and other drugs By feeds.nature.com Published On :: 2020-05-04 Full Article
gen Getting Smart on Pandemics: Intelligence in the Wake of COVID-19 By feedproxy.google.com Published On :: Apr 17, 2020 Apr 17, 2020This episode of Horns of a Dilemma touches on whether the failure to properly anticipate and warn about the novel coronavirus constitutes an intelligence failure, what changes might be required in the intelligence community in the wake of the pandemic, and what type of investigation or inquiry might be appropriate in order to learn lessons and incorporate changes for both the intelligence community and the whole of government moving forward. Full Article
gen Comments on “The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study” By feeds.nature.com Published On :: 2020-05-07 Full Article
gen Getting Smart on Pandemics: Intelligence in the Wake of COVID-19 By feedproxy.google.com Published On :: Apr 17, 2020 Apr 17, 2020This episode of Horns of a Dilemma touches on whether the failure to properly anticipate and warn about the novel coronavirus constitutes an intelligence failure, what changes might be required in the intelligence community in the wake of the pandemic, and what type of investigation or inquiry might be appropriate in order to learn lessons and incorporate changes for both the intelligence community and the whole of government moving forward. Full Article
gen Carmen Reinhart Says Argentina’s Debt Workout Won’t Be Its Last By feedproxy.google.com Published On :: Apr 27, 2020 Apr 27, 2020Argentina’s latest effort to restructure its overseas debt probably won’t be its last, according to Harvard University economist Carmen Reinhart, who has sounded alarms over coming emerging markets crises in Venezuela and Turkey. Full Article
gen Restructuring Argentina’s Private Debt is Essential By feedproxy.google.com Published On :: May 6, 2020 May 6, 2020Argentina's creditors are being asked to accept a proposal that would reduce their revenue stream but make it sustainable. A responsible resolution will set a positive precedent, not only for Argentina, but for the international financial system as a whole. Full Article
gen Getting Smart on Pandemics: Intelligence in the Wake of COVID-19 By feedproxy.google.com Published On :: Apr 17, 2020 Apr 17, 2020This episode of Horns of a Dilemma touches on whether the failure to properly anticipate and warn about the novel coronavirus constitutes an intelligence failure, what changes might be required in the intelligence community in the wake of the pandemic, and what type of investigation or inquiry might be appropriate in order to learn lessons and incorporate changes for both the intelligence community and the whole of government moving forward. Full Article
gen Genome-wide selection and genetic improvement during modern maize breeding By feeds.nature.com Published On :: 2020-04-27 Full Article
gen Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease By feeds.nature.com Published On :: 2020-04-27 Full Article
gen Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers By feeds.nature.com Published On :: 2020-04-27 Full Article
gen ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling By feeds.nature.com Published On :: 2020-03-05 Full Article
gen Correction to: AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs By feeds.nature.com Published On :: 2020-03-31 Full Article
gen Covid-19 tweeting in English: Gender differences By eprints.rclis.org Published On :: Sat, 09 May 2020 13:18:03 +0200 Thelwall, Mike and Thelwall, Saheeda Covid-19 tweeting in English: Gender differences. El profesional de la información, 2020, vol. 29, n. 3. [Journal article (Unpaginated)] Full Article
gen Carmen Reinhart Says Argentina’s Debt Workout Won’t Be Its Last By feedproxy.google.com Published On :: Apr 27, 2020 Apr 27, 2020Argentina’s latest effort to restructure its overseas debt probably won’t be its last, according to Harvard University economist Carmen Reinhart, who has sounded alarms over coming emerging markets crises in Venezuela and Turkey. Full Article
gen Restructuring Argentina’s Private Debt is Essential By feedproxy.google.com Published On :: May 6, 2020 May 6, 2020Argentina's creditors are being asked to accept a proposal that would reduce their revenue stream but make it sustainable. A responsible resolution will set a positive precedent, not only for Argentina, but for the international financial system as a whole. Full Article
gen Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels By feeds.nature.com Published On :: 2020-04-27 Full Article
gen Analyses of breakpoint junctions of complex genomic rearrangements comprising multiple consecutive microdeletions by nanopore sequencing By feeds.nature.com Published On :: 2020-04-30 Full Article
gen Genome-wide association study identifies zonisamide responsive gene in Parkinson’s disease patients By feeds.nature.com Published On :: 2020-05-01 Full Article
gen Correction to ‘Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation’ By feeds.nature.com Published On :: 2020-05-08 Full Article
gen Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World By feedproxy.google.com Published On :: Mar 4, 2020 Mar 4, 2020To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures. What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past. Full Article
gen Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World By feedproxy.google.com Published On :: Mar 4, 2020 Mar 4, 2020To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures. What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past. Full Article
gen Mechanisms governing autophagosome biogenesis By feeds.nature.com Published On :: 2020-05-05 Full Article