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The selective extraction of dietary polyamines from chicken breast using the application of a lab-on-a-chip electromembrane and dispersive liquid–liquid microextraction followed by gas chromatography-mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02172F, Paper
Fatemeh Barzegar, Samaneh Nabizadeh, Marzieh Kamankesh, Jahan B. Ghasemi, Abdorreza Mohammadi
Excessive dietary polyamines (PAs), including putrescine (PUT), spermine (SPM), and spermidine (SPD), have become a worldwide concern due to their carcinogenicity and reduced shelf life.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00492B, Paper
Juan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi Wang
A novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Direct solid sample analysis of low-cost jewelry using spectroanalytical techniques: exploratory chemical data evaluation and metal migration with synthetic sweat

Anal. Methods, 2024, 16,2286-2291
DOI: 10.1039/D4AY00325J, Paper
Thaila Lorena de Araújo, Fabiola Manhas Verbi Pereira, Edenir Rodrigues Pereira-Filho
Jewelry samples were directly analyzed using LIBS and XRF.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00487F, Paper
Jinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang Liu
Small extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Solutions and Tools for Dealing with Broken Links in Web Pages

A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down.

I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links.

The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs.



  • HTML5
  • Web Design Articles

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Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content

[Sponsored] If you’re building an app that requires a lot of user-generated content and media that needs to be processed, tagged, filtered, or otherwise manipulated in real-time, you definitely want a solution that’s fast and seamless and doesn’t get in the way of your app’s primary functionality. Filestack is a service you’ll want to consider. Here’s what Filestack offers:

The post Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content appeared first on Impressive Webs.




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​Weather gods: On ‘Mission Mausam’

Attempts at controlling the weather are still in the realm of uncertainty




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Third front: On the expanding nature of the conflict in West Asia

Israel’s fighting three enemy militias at once highlights the pressing need for a ceasefire




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A way out: On the government and doctor-led protests in West Bengal

The West Bengal government must enable the changes doctors want to see




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​The edge of war: On the West Asia situation

Iran should not give Israel an excuse to widen the war




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​Inflection point: On the escalation in the multi-party West Asia conflict

West Asia needs the intervention of major world powers for peace 




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Split decision: On the rivalry between the two NCP factions

The ECI and the office of the Speaker have not played fair in cases of defection




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Sweet and sour: On the laddu ‘adulteration’ case  

The inquiry into laddu adulteration must not be communalised




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Deeper role: On the U.S. and West Asia conflicts   

The escalating conflict cycle in West Asia could have disastrous consequences




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​West versus the rest: On western conduct and India

The West must not tolerate terror threats in the name of free speech 




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Cost of Games: On the 2026 Commonwealth Games 

Taking out popular sports from the CWG is a short-term solution 




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​Escalation ladder: On conflict between Israel and Iran

Iran should show strategic restraint; and the world should rein in Israel




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Western front: On the parties and their prospects in the Maharashtra polls

Granular factors can determine the outcome in Maharashtra 




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Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation

RSC Med. Chem., 2024, 15,3529-3557
DOI: 10.1039/D4MD00481G, Research Article
Mohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai Adel
Discovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Heavy weed growth at Kasi Viswanathar Temple tank prevents replenishing of underground water table, say Tiruchi residents




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Power shutdown in parts of Tiruchi on November 9




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Art and literary contests lined up for District Central Library’s National Library Week




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542: Breaking Up with CSS-in-JS, Mastodon, and Stories on the Web

We're talking CSS-in-JS, Token CSS, Matuzo being suspended from Twitter, trying out Mastodon, testing out stable diffusion, stories on the web, and Jake Albaugh's new social network.




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544: Feedback, RSS Talk, Arc Brower, and Product Talk

Getting feedback for what you're building or writing, RSS feed reminiscing, Arc browser thoughts, products that didn't make that should have.




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557: ChatGPT, Conferences, Fidgets on the Web, and Modern CSS in Real Life

When will AI be able to tell you the risk / reward of cleaning up trees? Are conferences back? Bringing fidgets to the web, internet as an anxiety machine, and Chris is working on talk on modern CSS in real life.




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558: Esoteric Weird Content Editable Problems with Kristin Valentine

Kristin Valentine from Vox joins the show to talk about text editor CMS fun across multiple sites, Vox's Chorus, The Verge redesign, sharing Design Systems, theming articles, and a fun new game called "Can Your Text Editor Do This??"




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561: Web Perf News, Web Sommelier, Data Analytics, and Passkeys

Topics for this one include how do you learn about web performance news? Do you need a web components sommelier? Our thoughts on Syntax going to Sentry, and being able to focus on the things you want to focus on. Passkeys, Arc split screen, and vibe driven development.




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569: Apple’s Web Apps, Meta Quest and Vision Pro, and Missing Sticky Headers

How do you point out things in a UI? Are Arc Boosts the end of the web? What do you think of VR and AR / Vision Pro and Meta Quest? And what do you do when the sticky header goes missing?




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571: Searching vs AI, Getting Designers to Play Nice, and Web Components

Do you listen at 2x? Do Chris and Dave sound weird at normal speed IRL? How searching compares to using AI, chatbots kind of suck at context, getting a designer to work with developers at an agency, what happened to content visibility, and how to best build a design system using web components.




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576: Blocks, Components, Linting Images, Engines, and “Web Integrity”

We're talking how we stay online - or not - on vacation, is create-guten-block the future for us WP developers? Can we get a state of the web component address from the President of web components? Have we seen the last new browser engine? And deciding whether to add features or remove them from your app.




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585: Blog Redesign, Sounds on a Website, Accessibility Tests, and Safari 17

Chris redesigned his blog, using sounds on your website to make it seem fancy, what can't automated accessibility tests test, and what's new in Safari 17.




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588: Elliott Marquez on Web Components and Lit

Elliot Marquez talks with us about the history of Polymer and Lit, why you should pick Lit, working with web components, the shadow dom, managing state, and how Material design is built with web components.




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590: Twisting Through Websites

The excitement of launching Luro, changes in social media platforms, different seasons for coding and marketing, embedded social media post weight, CSS thoughts from Web Unleashed, focus state issues, and fact checking and updating old posts on your blog.




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592: Web Component Therapy, SEO Therapy, and Learning Something New like Swift

Talking web components, progressive enhancement, style-able components, having to pay before you get to see a demo, being annoyed at the business of SEO, and subscriptions vs ads.




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593: Beep & Texts, Tumblr, JavaScript & Web Components, & Cool Blog Post Ideas

Thoughts on smashing all communication messaging apps together, what's happened to Tumblr under Automattic, what the situation is with native web components and JavaScript, and looking at a list of types of blog posts.




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595: MedTalk Show, Plagiarism and Code Grifting, and How We’re Testing Code

Blood pressure, stress, and COVID highlight the MedTalk Show portion of this episode, a new "Did You Know" segment about dev tools in Chrome, 4 hour video on plagiarism and code grifters, typography, breaking out of CSS Grid, the oldest things Chris and Dave worked on, and what the testing process is like at Luro or CodePen.




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598: Jen Simmons on Interop, WebKit Releases, and New CSS Features in Safari

Jen Simmons, Apple Evangelist on the Web Developer Experience team for Safari & Webkit, stops by to talk about what Interop is, and a look ahead at new CSS features in Webkit and Safari such as JPEG XL, masks, a round function, JavaScript improvements, styling form controls, content unblocks, masonry, and more!




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599: Fighting the Algorithm With RSS, Blogging, and the IndieWeb

Dave and Chris discuss indie web culture, the role of social media in today's society, and the challenges and strategies of freelancing. Additionally, they discuss a range of topics from content moderation, coding and refining tech skills, to emerging startups and the future of web technology.




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600: Where Will The Web Be 12 Years from Now?

We've got your feedback as well as our thoughts on where we all think the web will be in 2036 - as we celebrate 12 years of ShopTalk Show history, we're looking forward to what's to come with ideas around cookie banners, undo, no more passwords, React, Deno, Node, and Mozilla's future, ChatGPT's thoughts, accessibility, blockchain, VR / AR, hoverboards, P3 color space, indie web, JS bundle sizes, and more!




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606: Web Sustainability with Michelle Barker

Show DescriptionWe're talking with Michelle Barker about the idea of paying to support bloggers (and podcasters!) via services like Patreon, drumming as a fun side gig from CSS, how big of an issue digital sustainability is, trying to understand the environmental impact of our websites and digital life, wondering why YouTube embeds are still so […]




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608: Can WordPress Kill Your Resume, Fav Parts of Web Dev, Exploring HTMX, and more!

We're opening up the ShopTalk mailbag and answering your questions, including does WordPress on your resume kill your job chances, what are our fav and least fav parts of web dev, our thoughts on HTMX, and what is it like to use pnpm instead of npm.




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613: Recording Live Music, WebC, Open Source, & WordPress Studio

Chris bought recording gear off an Instagram ad, our thoughts on WebC, CodePen upgrades Yarn, thoughts on the commercial value of open source, Automattic releases an app to install WordPress locally, IBM buys Hashicorp, income tax software, and a hack for getting Safari to respect background colors used in a pseudo selector.




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622: Website Rendering, Updating Software, and Edge Gets Faster

We're talking website rendering, server side rendering, Astro's server islands, perf hits for navigation elements, updating software because the docs aren't available for older versions, and a new Microsoft Edge was released.




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623: Assigning Weight Dynamically, CoPilot vs Other AI, and Monorepos

We're talking about assigning a weight to items in a layout, differentiating between banger posts and regular blog posts, using social engineering to get PR's accepted, monorepo thoughts, using CoPilot vs other AI programming support bots, has TypeScript benefited from AI, and what happens if you turn off CoPilot?




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626: We Were Wrong and Keep Getting in Trouble

Chris has some follow up on blog posts and past podcast episodes to respond to including browsers and browser engines, advertising on the web, magazines, Cara, peak AI slop, and view transitions.




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629: The Great Divide, Global Design + Web Components, and Job Titles

A bit of follow-up on vibe driven development and JavaScript not causing The Great Divide, writing testing automation, global design systems and web components, could PHP be used for web components, what if view transitions are going to be everywhere, and frontend engineer vs design systems engineer job titles and descriptions.




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633: Thomas Steiner on AI in Chrome and the Web

Thomas Steiner from Project Fugu talks with us about AI in Chrome, the small large language model in use, how features like this are rolled out, the ethics and concerns around sending and sharing data, on device vs web APIs, and ideas for use cases and ways to explore AI on the web.




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636: W Hot Drama Week (WordPress, WP Engine, and Web Components – Oh My!)

We're getting some feelings out about WordPress and Matt Mullenweg vs WP Engine drama, as well as the Web Components conversation that happened this past week.




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640: Navigating the Pros and Cons of Web Components

Riffing off a Dave Rupert blog post, Chris and Dave talk through the pros and cons of web components, when to use them, when it's a bad idea to use them, what would it take to make the Next.js of web components, and how long until we don't need anymore frameworks?




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Webcams & borewells

A groundwater expert uses a webcam to find out the yield from borewells and identify problems. By