La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

The recent High Court decision in Amey Highways Limited v West Sussex County Council has clarified that abandoning a procurement will not automatically extinguish pre-existing causes of action.  Breaches of the procurement regulations which res...

Little Richard, the flamboyant, piano-pounding showman who injected sheer abandon into rock ’n’ roll in its early days, only to abandon the music again and again because it conflicted with his religious yearnings, died Saturday. He was 87. Pastor Bill Minson, a close friend of the singer, confirmed his death to the Associated Press. Minson said he also spoke to Little Richard’s son and brother. Minson added that the family is not releasing the cause of death. In hits such as “Tutti-Frutti,” “Long Tall Sally” and “Good Golly, Miss Molly,” the singer pushed the limits of tempo and vocal intensity, creating frantic explosions of sonic confetti. His records entered a pure, primal realm that...

A little over half of women across the globe are able to freely make choices about their sexual and reproductive health, according to a latest report based on data from 57 countries.  However, as much of the world has gone into lockdown because of the coronavirus pandemic, with countries implementing social distancing and restricting the […]

The post **Correction**How the COVID-19 Pandemic is Affecting Women’s Sexual and Reproductive Health appeared first on Inter Press Service.

For a Bangladeshi woman, who has worked as a sex worker since childhood, her future post-COVID-19 looks hopeless. Shilpy, who works at Daulatdia, the largest brothel in the country, told IPS how she now also fears for the future of her two daughters. “When I was born, the woman my mother worked for gave everyone […]

The post Alive Amidst the Mayhem of COVID-19 – A Sex Worker’s Story appeared first on Inter Press Service.

Ensuring sex workers’ rights was essential, not just for the workers themselves, but for any country’s wider society, including public health

The post Ensuring Russia’s Sex Workers’ Rights Essential for Wider Gender Equality appeared first on Inter Press Service.

On 15 January 2020, the Equalities and Human Rights Commission (“EHRC”) published new and comprehensive technical guidance setting out the law and best practice on the prevention of workplace sexual harassment and harassment. The guidanc...

The issue of harassment and sexual misconduct has been a high profile one now for some time with widespread local and national coverage across multiple sectors and jurisdictions. This has included copious discussion and analysis of the issue in the ...

Five teachers at a public school in Mukdahan have been suspended after being charged in connection with repeated sexual assaults against a 14-year-old girl. Two school alumni are also accused of having taken part, and all are said to have taken video of the acts.

South Korean Olympic short-track speedskating gold medallist Lim Hyo-jun was convicted Thursday of sexually harassing a fellow male athlete by pulling down his trousers, a ...

While releasing the Annual Crime Report for 2019 recently, the Inspector General of Police, Mr Martin Okoth Ochola, revealed that defilement still poses a big problem to the police.

A study by doctors at China's Shangqiu Municipal Hospital of 38 men hospitalized with the disease found that six of them, or 16%, tested positive for SARS-CoV-2 in their semen.

Chinese researchers have found Covid-19 in the sperm of a small number of men, raising the possibility that the virus could be spread via sex.The study by physicians at China’s Shangqiu Municipal Hospital looked at only 38 men at the hospital who had tested positive with disease, and of that already small group found that a minority – only six – were found to have SARS-CoV-2 in their semen.Eyes are ‘important route’ for coronavirus into body, Hong Kong experts find“The virus responsible for…

Former US Senate aide Tara Reade said on Thursday that presumptive Democratic presidential nominee Joe Biden should acknowledge her claim that he sexually assaulted her is true and quit the 2020 presidential race.“You and I were there, Joe Biden. Please step forward and be held accountable. You should not be running on character for the president of the United States,” Reade said during her first on-camera interview since Biden appeared on MSNBC last week and denied her accusation for the first…

“Wow, your shirt is really see-through. Are you wearing matching underwear?” the man says lewdly.It’s a virtual reality simulation – but it’s enough to shock 23-year-old Elizabeth Lee into silence as the scene plays out on her headset.The VR technology is part of the Girl, Talk project which is aimed at helping women fight back against harassment in Singapore.“I would think that I would respond in a more confrontational way,” Lee admits. “It felt very physically close … it was just really…

A Hong Kong man has admitted in court to raping his nine-year-old daughter and telling his younger son that it was none of his business when the child caught him in the act.The High Court heard the sexual attacks spanned nearly six years, since 2011, when the casual vegetable seller, who could not be identified for legal reasons, first attempted to rape his daughter after school.At the time she was only six, while he was 40.Acting deputy director of public prosecutions Catherine Ko said the…

Sona Mohapatra recently called out controversial filmmaker Ram Gopal Varma after he made a sexist remark

When the nightclub in which she touted for business in southern Chile was shut down by the authorities as the new coronavirus spread, sex worker Camila Hormazabal was left without access to her sole...

An analysis of the topics that cause arguments between newly-wed heterosexual couples puts a lack of affection at the top of the list, with little concern about who sleeps on which side of the bed

Title: Fewer Teens Are Having Sex
Category: Health News
Created: 5/4/2012 11:00:00 AM
Last Editorial Review: 5/4/2012 12:00:00 AM

Title: Your Voice Carries Sexual Cues, Study Finds
Category: Health News
Created: 4/29/2013 6:36:00 PM
Last Editorial Review: 4/30/2013 12:00:00 AM

Title: Sex Lives Often an Overlooked Casualty of Traumatic Brain Injury
Category: Health News
Created: 4/29/2013 2:35:00 PM
Last Editorial Review: 4/30/2013 12:00:00 AM

Title: Young Gay, Bisexual Men May Be at Higher Risk for Suicide, Study Finds
Category: Health News
Created: 4/26/2016 12:00:00 AM
Last Editorial Review: 4/27/2016 12:00:00 AM

Title: Sex Still Matters to Many Seniors, Survey Finds
Category: Health News
Created: 5/3/2018 12:00:00 AM
Last Editorial Review: 5/4/2018 12:00:00 AM

Title: You Can't Get Coronavirus Through Sex, Study Suggests
Category: Health News
Created: 4/27/2020 12:00:00 AM
Last Editorial Review: 4/27/2020 12:00:00 AM

Title: Is Coronavirus Also Sexually Transmitted?
Category: Health News
Created: 5/7/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM

Title: Less Sex Could Mean Earlier Menopause
Category: Health News
Created: 1/15/2020 12:00:00 AM
Last Editorial Review: 1/16/2020 12:00:00 AM

Pediatricians are encouraged to address male adolescent sexual and reproductive health on a regular basis, including taking a sexual history, discussing healthy sexuality, performing an appropriate physical examination, providing patient-centered and age-appropriate anticipatory guidance, and administering appropriate vaccinations. These services can be provided to male adolescent patients in a confidential and culturally appropriate manner, can promote healthy sexual relationships and responsibility, can and involve parents in age-appropriate discussions about sexual health.

OBJECTIVES:

In this study, we evaluate the efficacy of Families Talking Together (FTT), a triadic intervention to reduce adolescent sexual risk behavior.

Many complex human traits exhibit differences between sexes. While numerous factors likely contribute to this phenomenon, growing evidence from genome-wide studies suggest a partial explanation: that males and females from the same population possess differing genetic architectures. Despite this, mapping gene-by-sex (GxS) interactions remains a challenge likely because the magnitude of such an interaction is typically and exceedingly small; traditional genome-wide association techniques may be underpowered to detect such events, due partly to the burden of multiple test correction. Here, we developed a local Bayesian regression (LBR) method to estimate sex-specific SNP marker effects after fully accounting for local linkage-disequilibrium (LD) patterns. This enabled us to infer sex-specific effects and GxS interactions either at the single SNP level, or by aggregating the effects of multiple SNPs to make inferences at the level of small LD-based regions. Using simulations in which there was imperfect LD between SNPs and causal variants, we showed that aggregating sex-specific marker effects with LBR provides improved power and resolution to detect GxS interactions over traditional single-SNP-based tests. When using LBR to analyze traits from the UK Biobank, we detected a relatively large GxS interaction impacting bone mineral density within ABO, and replicated many previously detected large-magnitude GxS interactions impacting waist-to-hip ratio. We also discovered many new GxS interactions impacting such traits as height and body mass index (BMI) within regions of the genome where both male- and female-specific effects explain a small proportion of phenotypic variance (R² < 1 x 10^–4), but are enriched in known expression quantitative trait loci.

Ewa Komar, Dina K. N. Dechmann, Nicolas J. Fasel, Marcin Zegarek, and Ireneusz Ruczynski

Balancing energy budgets can be challenging, especially in periods of food shortage, adverse weather conditions and increased energy demand due to reproduction. Bats have particularly high energy demands compared to other mammals and regularly use torpor to save energy. However, while torpor limits energy expenditure, it can also downregulate important processes, such as sperm production. This constraint could result in a trade-off between energy saving and future reproductive capacity. We mimicked harsh conditions by restricting food and tested the effect on changes in body mass, torpor use and seasonal sexual maturation in male parti-coloured bats (Vespertilio murinus). Food-restricted individuals managed to maintain their initial body mass, while in well-fed males, mass increased. Interestingly, despite large differences in food availability, there were only small differences in torpor patterns. However, well-fed males reached sexual maturity up to half a month earlier. Our results thus reveal a complex trade-off in resource allocation; independent of resource availability, males maintain a similar thermoregulation strategy and favour fast sexual maturation, but limited resources and low body mass moderate this latter process.

Noemie Liesch and Friedrich Ladich

In vocal fish species, males possess larger sound-generating organs and signal acoustically with pronounced sex-specific differences. Sound production is known in two out of three species of croaking gouramis (Trichopsis vittata and T. schalleri). The present study investigates sex-specific differences in sonic organs, vocalizing behaviour and sounds emitted in the third species, the pygmy gourami T. pumila, in order to test the hypothesis that females are able to vocalize despite their less-developed sonic organs, and despite contradictory reports. Croaking gouramis stretch and pluck two enhanced (sonic) pectoral fin tendons during alternate fin beating, resulting in a series of double-pulsed bursts termed croaking sound. We measured the diameter of the first and second sonic tendon and showed that male tendons were twice as large as in same-sized females. We also determined the duration of dyadic contests, visual displays, number of sounds and buttings. Sexes differ in all sound characteristics but in no behavioural variable. Male sounds consisted of twice as many bursts, a higher percentage of double-pulsed bursts and a higher burst period. Additionally, male sounds had a lower dominant frequency and a higher sound level. In summary, female pygmy gouramis possessed sonic organs and vocalized in most dyadic contests. The sexual dimorphism in sonic tendons is clearly reflected in sex-specific differences in sound characteristics, but not in agonistic behaviour, supporting the hypothesis that females are vocal.

Screening for Chlamydia trachomatis and Neisseria gonorrhoeae at the pharyngeal, urogenital, and anorectal sites is recommended for men who have sex with men (MSM). Combining the three individual-site samples into a single pooled sample could result in significant cost savings, provided there is no significant sensitivity reduction. The aim of this study was to examine the sensitivity of pooled samples for detecting chlamydia and gonorrhea in asymptomatic MSM using a nucleic acid amplification test. Asymptomatic MSM who tested positive for chlamydia or gonorrhoea were invited to participate. Paired samples were obtained from participants prior to administration of treatment. To form the pooled sample, the anorectal swab was agitated in the urine specimen transport tube and then discarded. The pharyngeal swab and 2 ml of urine sample were then added to the tube. The difference in sensitivity between testing of pooled samples and individual-site testing was calculated against an expanded gold standard, where an individual is considered positive if either pooled-sample or individual-site testing returns a positive result. All samples were tested using the Aptima Combo 2 assay. A total of 162 MSM were enrolled in the study. Sensitivities of pooled-sample testing were 86% (94/109; 95% confidence interval [CI], 79 to 92%]) for chlamydia and 91% (73/80; 95% CI, 83 to 96%) for gonorrhea. The sensitivity reduction was significant for chlamydia (P = 0.02) but not for gonorrhea (P = 0.34). Pooling caused 22 infections (15 chlamydia and 7 gonorrhoea) to be missed, and the majority were single-site infections (19/22). Pooling urogenital and extragenital samples from asymptomatic MSM reduced the sensitivity of detection by approximately 10% for chlamydia but not for gonorrhea.

Pre-eclampsia (PE)-induced fetal programming predisposes offspring to health hazards in adult life. Here, we tested the hypothesis that pre-eclamptic fetal programming elicits sexually dimorphic inflammatory and cardiovascular complications to endotoxemia in adult rat offspring. PE was induced by oral administration of L-NAME (50 mg/kg per day for seven consecutive days) starting from day 14 of conception. Cardiovascular studies were performed in conscious adult male and female offspring preinstrumented with femoral indwelling catheters. Compared with non-PE male counterparts, intravenous administration of lipopolysaccharide (LPS, 5 mg/kg) to PE male offspring caused significantly greater 1) falls in blood pressure, 2) increases in heart rate, 3) rises in arterial dP/dtmax, a correlate of left ventricular contractility, and 4) decreases in time- and frequency-domain indices of heart rate variability (HRV). By contrast, the hypotensive and tachycardic actions of LPS in female offspring were independent of the pre-eclamptic state and no clear changes in HRV or dP/dtmax were noted. Measurement of arterial baroreflex activity by vasoactive method revealed no sex specificity in baroreflex dysfunction induced by LPS. Immunohistochemical studies showed increased protein expression of toll-like receptor 4 in heart as well as in brainstem neuronal pools of the nucleus of solitary tract and rostral ventrolateral medulla in endotoxic PE male, but not female, offspring. Enhanced myocardial, but not neuronal, expression of monocyte chemoattractant protein-1 was also demonstrated in LPS-treated male offspring. Together, pre-eclamptic fetal programming aggravates endotoxic manifestations of hypotension and autonomic dysfunction in male offspring via exacerbating myocardial and neuromedullary inflammatory pathways.

ABSTRACTBackground:Female sex workers (FSWs) in Cameroon commonly have unmet need for contraception posing a high risk of unintended pregnancy. Unintended pregnancy leads to a range of outcomes, and due to legal restrictions, FSWs often seek unsafe abortions. Aside from the high burden of HIV, little is known about the broader sexual and reproductive health of FSWs in Cameroon.Methods:From December 2015 to October 2016, we recruited FSWs aged ≥18 years through respondent-driven sampling across 5 Cameroonian cities. Cross-sectional data were collected through a behavioral questionnaire. Modified-robust Poisson regression was used to approximate adjusted prevalence ratios (aPR) for TOP and current use of effective nonbarrier contraception.Results:Among 2,255 FSWs (median age 28 years), 57.6% reported history of unintended pregnancy and 40.0% reported prior TOP. In multivariable analysis, TOP history was associated with current nonbarrier contraceptive use (aPR=1.23, 95% confidence interval [CI]=1.07, 1.42); ever using emergency contraception (aPR=1.34, 95% CI=1.17, 1.55); >60 clients in the past month (aPR=1.29, 95% CI= 1.07, 1.54) compared to ≤30; inconsistent condom use with clients (aPR=1.17, 95% CI=1.00, 1.37); ever experiencing physical violence (aPR=1.24, 95% CI=1.09, 1.42); and older age. Most (76.5%) women used male condoms for contraception, but only 33.2% reported consistent condom use with all partners. Overall, 26.4% of women reported currently using a nonbarrier contraceptive method, and 6.2% reported using a long-acting method. Previous TOP (aPR=1.41, 95%CI=1.16, 1.72) and ever using emergency contraception (aPR=2.70, 95% CI=2.23, 3.26) were associated with higher nonbarrier contraceptive use. Recent receipt of HIV information (aPR=0.72, 95% CI=0.59, 0.89) and membership in an FSW community-based organization (aPR=0.73, 95% CI=0.57, 0.92) were associated with lower use nonbarrier contraceptive use.Conclusions:Experience of unintended pregnancies and TOP is common among FSWs in Cameroon. Given the low use of nonbarrier contraceptive methods and inconsistent condom use, FSWs are at risk of repeat unintended pregnancies. Improved integration of client-centered, voluntary family planning within community-led HIV services may better support the sexual and reproductive health and human rights of FSWs consistent with the United Nations Declaration of Human Rights.

BACKGROUND

Sex differences have been described in diabetes cardiovascular outcome trials (CVOTs).

Yuta Sakae, Akira Oikawa, Yuki Sugiura, Masatoshi Mita, Shuhei Nakamura, Toshiya Nishimura, Makoto Suematsu, and Minoru Tanaka

The teleost fish, medaka (Oryzias latipes), employs the XX/XY genetic sex determination system. We show here that the phenotypic sex of medaka is affected by changes in lipid metabolism. Medaka larvae subjected to 5 days of starvation underwent female-to-male sex reversal. Metabolomic and RT-qPCR analyses indicated that pantothenate metabolism was suppressed by starvation. Consistently, inhibiting the pantothenate metabolic pathway caused sex reversal. The final metabolite in this pathway is coenzyme A, an essential factor for lipogenesis. Inhibiting fatty acid synthesis, the first step of lipogenesis, also caused sex reversal. The expression of dmrt1, a critical gene for male development, was suppressed by starvation, and a dmrt1 (13) mutant did not show sex reversal under starvation. Collectively, these results indicate that fatty acid synthesis is involved in female-to-male sex reversal through ectopic expression of male gene dmrt1 under starvation.

Background:

Sex steroid hormones and sex hormone–binding globulin (SHBG) have been implicated in the etiology of invasive breast cancer, but their associations with risk of the precursor lesion, ductal carcinoma in situ (DCIS) of the breast, remain unclear.

For the past two months, Katie Holliday has been cooped up alone in her Brooklyn apartment thinking longingly about an unlikely erogenous zone: the lower half of a stranger’s face. 

“I remember joking to my friend before all of this started, ‘Imagine if someone’s face becomes their most coveted body part?’” Holliday, who is 31, told The Daily Beast. “‘When someone removes their mask, is it a sign of trust? Is it like letting someone see you naked?’ I was kidding back then, but now it’s reality.”

Holliday doesn’t know exactly when it will be safe to start seeing people like she did before the pandemic began, but she’ll return to a singles scene unlike any other in history. “I’m picturing walking into a bar where everyone’s wearing masks,” she said. “I’ll meet someone whose face is covered. Are they cute or not? I don’t know!” 

Read more at The Daily Beast.

It’s not going out on much of a limb to say that the single greatest line in any rock and roll song—shall we double down and say all music ever?—is “A-wop-bom-a-loo-mop-a-lomp-bom-bom!!”

Surely that says it all.

As with any truly oracular pronouncement, it inspires consternation in the first-time listener, and the second-time listener, and the third, the fourth, and on and on. The mystery never diminishes.

Read more at The Daily Beast.

We know many of you need comfort in these dark times. RPGCast is here and hopes to be an escape from the worries and tribulations...

Julia Garner excels as a junior assistant to a predatory media mogul boss in Kitty Green’s powerfully understated #MeToo drama

A performance of few words but immense physical eloquence by Julia Garner anchors this impressively chilling #MeToo-era drama about workplace harassment and abuse. Following a day in the life of a young woman with dreams of making her mark in the film and television industry, it’s a sobering portrait of a dirty little secret that was brought into the news spotlight by the Harvey Weinstein scandal. All the more powerful for its understated tone, this low-key piece packs a hefty punch as it exposes the web of silence that enabled a very modern horror story.

Garner (who won an Emmy for her work on TV’s Ozark) is Jane, a high-achieving college graduate who finds herself on the bottom rung of the ladder as a junior assistant to an unnamed entertainment mogul in New York. The appointment may hold promises of great opportunities ahead, but for now it’s fairly soul destroying. An opening sequence, played out to the lonely strains of Tamar-kali’s sparse score, finds Jane being driven to the office before dawn, turning on the lights above her colleagues’ desks – first in, last out. Her tasks are menial yet weirdly demanding: making coffee, changing the paper in the photocopier, ordering lunch, and arranging travel and accommodation for an ever-changing roster of offhand executives and needy clients.

Once the ‘go-to guy for feckless losers’, the actor is now spearheading Apple’s assault on British TV. He talks about flops, racism, chest hair – and Laurence Fox

In October 2005, Rafe Spall was starring in the role he thought he was born to play. Only 21 at the time, he’d bagged a part in Anna Mackmin’s reimagining of Francis Beaumont’s 1607 comedy The Knight of the Burning Pestle at the Barbican. The play isn’t just any old Renaissance play in the Spall household, it’s a hallowed text.

His father (Timothy Spall, you might have heard of him) had played the same part in a 1981 RSC version that changed his life for ever. It was while playing that role he met his wife, Shane, and the pair loved the play so much they decided to give their first child the name of the character his father played: Rafe. To make it seem even more preordained, it was Rafe’s grandmother’s favourite ever performance by his father. No pressure, then.

The director of King of New York, Bad Lieutenant and The Funeral recommends film and TV for a coronavirus age, in the hope that ‘the light becomes more evident in the darkness’

• Read the rest of our Lockdown watch series
• The best arts and entertainment during self-isolation

The Day the Earth Stood Still (1951)

Bill Maher said Republicans "don't care" about Tara Reade's sexual assault allegations, saying such claims are simply used as a "unilateral weapon" against Democrats.

Patients in China were found to have evidence of COVID-19 in their semen several days after they stopped displaying symptoms of the coronavirus