date Vaccination 101: Make Sure Kids Are Up to Date By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Vaccination 101: Make Sure Kids Are Up to DateCategory: Health NewsCreated: 8/28/2017 12:00:00 AMLast Editorial Review: 8/28/2017 12:00:00 AM Full Article
date Half of American Workers Support COVID Vaccination, Mask Mandates in Workplace By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Half of American Workers Support COVID Vaccination, Mask Mandates in WorkplaceCategory: Health NewsCreated: 8/27/2021 12:00:00 AMLast Editorial Review: 8/27/2021 12:00:00 AM Full Article
date The Priority Updates from the Research Literature (PURLs) Methodology By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Full Article
date The Evolution of Intermittent Mandatory Ventilation: Update and Implications for Home Care By rc.rcjournal.com Published On :: 2024-10-25T05:44:13-07:00 Full Article
date Low-Efficacy Mu Opioid Agonists as Candidate Analgesics: Effects of Novel C-9 Substituted Phenylmorphans on Pain-Depressed Behavior in Mice [Behavioral Pharmacology] By jpet.aspetjournals.org Published On :: 2024-10-18T07:04:15-07:00 Low-efficacy mu opioid receptor (MOR) agonists may serve as novel candidate analgesics with improved safety relative to high-efficacy opioids. This study used a recently validated assay of pain-depressed behavior in mice to evaluate a novel series of MOR-selective C9-substituted phenylmorphan opioids with graded MOR efficacies. Intraperitoneal injection of dilute lactic acid (IP acid) served as a noxious stimulus to depress locomotor activity by mice in an activity chamber composed of two compartments connected by an obstructed door. Behavioral measures included (1) crosses between compartments (vertical activity over the obstruction) and (2) movement counts quantified as photobeam breaks summed across compartments (horizontal activity). Each drug was tested alone and as a pretreatment to IP acid. A charcoal-meal test and whole-body-plethysmography assessment of breathing in 5% CO2 were also used to assess gastrointestinal (GI) inhibition and respiratory depression, respectively. IP acid produced a concentration-dependent depression in crosses and movement that was optimally alleviated by intermediate- to low-efficacy phenylmorphans with sufficient efficacy to produce analgesia with minimal locomotor disruption. Follow-up studies with two low-efficacy phenylmorphans (JL-2-39 and DC-1-76.1) indicated that both drugs produced naltrexone-reversible antinociception with a rapid onset and a duration of ~1 h. Potency of both drugs increased when behavior was depressed by a lower IP-acid concentration, and neither drug alleviated behavioral depression by a non-pain stimulus (IP lithium chloride). Both drugs produced weaker GI inhibition and respiratory depression than fentanyl and attenuated fentanyl-induced GI inhibition and respiratory depression. Results support further consideration of selective, low-efficacy MOR agonists as candidate analgesics. SIGNIFICANCE STATEMENT This study used a novel set of mu opioid receptor (MOR)-selective opioids with graded MOR efficacies to examine the lower boundary of MOR efficacy sufficient to relieve pain-related behavioral depression in mice. Two novel low-efficacy opioids (JL-2-39, DC-1-76.1) produced effective antinociception with improved safety relative to higher- or lower-efficacy opioids, and results support further consideration of these and other low-efficacy opioids as candidate analgesics. Full Article
date The Updated Registry of Fast Myocardial Perfusion Imaging with Next-Generation SPECT (REFINE SPECT 2.0) By jnm.snmjournals.org Published On :: 2024-11-01T04:25:31-07:00 The Registry of Fast Myocardial Perfusion Imaging with Next-Generation SPECT (REFINE SPECT) has been expanded to include more patients and CT attenuation correction imaging. We present the design and initial results from the updated registry. Methods: The updated REFINE SPECT is a multicenter, international registry with clinical data and image files. SPECT images were processed by quantitative software and CT images by deep learning software detecting coronary artery calcium (CAC). Patients were followed for major adverse cardiovascular events (MACEs) (death, myocardial infarction, unstable angina, late revascularization). Results: The registry included scans from 45,252 patients from 13 centers (55.9% male, 64.7 ± 11.8 y). Correlating invasive coronary angiography was available for 3,786 (8.4%) patients. CT attenuation correction imaging was available for 13,405 patients. MACEs occurred in 6,514 (14.4%) patients during a median follow-up of 3.6 y (interquartile range, 2.5–4.8 y). Patients with a stress total perfusion deficit of 5% to less than 10% (unadjusted hazard ratio [HR], 2.42; 95% CI, 2.23–2.62) and a stress total perfusion deficit of at least 10% (unadjusted HR, 3.85; 95% CI, 3.56–4.16) were more likely to experience MACEs. Patients with a deep learning CAC score of 101–400 (unadjusted HR, 3.09; 95% CI, 2.57–3.72) and a CAC of more than 400 (unadjusted HR, 5.17; 95% CI, 4.41–6.05) were at increased risk of MACEs. Conclusion: The REFINE SPECT registry contains a comprehensive set of imaging and clinical variables. It will aid in understanding the value of SPECT myocardial perfusion imaging, leverage hybrid imaging, and facilitate validation of new artificial intelligence tools for improving prediction of adverse outcomes incorporating multimodality imaging. Full Article
date Ependymal Tumors: Overview of the Recent World Health Organization Histopathologic and Genetic Updates with an Imaging Characteristic [CLINICAL PRACTICE] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 SUMMARY: The 2021 World Health Organization Classification of Tumors of the Central Nervous System (CNS5), introduced significant changes, impacting tumors ranging from glial to ependymal neoplasms. Ependymal tumors were previously classified and graded based on histopathology, which had limited clinical and prognostic utility. The updated CNS5 classification now divides ependymomas into 10 subgroups based on anatomic location (supratentorial, posterior fossa, and spinal compartment) and genomic markers. Supratentorial tumors are defined by zinc finger translocation associated (ZFTA) (formerly v-rel avian reticuloendotheliosis viral oncogene [RELA]), or yes-associated protein 1 (YAP1) fusion; posterior fossa tumors are classified into groups A (PFA) and B (PFB), spinal ependymomas are defined by MYCN amplification. Subependymomas are present across all these anatomic compartments. The new classification kept an open category of "not elsewhere classified" or "not otherwise specified" if no pathogenic gene fusion is identified or if the molecular diagnosis is not feasible. Although there is significant overlap in the imaging findings of these tumors, a neuroradiologist needs to be familiar with updated CNS5 classification to understand tumor behavior, for example, the higher tendency for tumor recurrence along the dural flap for ZFTA fusion-positive ependymomas. On imaging, supratentorial ZFTA-fused ependymomas are preferentially located in the cerebral cortex, carrying predominant cystic components. YAP1-MAMLD1-fused ependymomas are intra- or periventricular with prominent multinodular solid components and have significantly better prognosis than ZFTA-fused counterparts. PFA ependymomas are aggressive paramedian masses with frequent calcification, seen in young children, originating from the lateral part of the fourth ventricular roof. PFB ependymomas are usually midline, noncalcified solid-cystic masses seen in adolescents and young adults arising from the fourth ventricular floor. PFA has a poorer prognosis, higher recurrence, and higher metastatic rate than PFB. Myxopapillary spinal ependymomas are now considered grade II due to high recurrence rates. Spinal-MYCN ependymomas are aggressive tumors with frequent leptomeningeal spread, relapse, and poor prognosis. Subependymomas are noninvasive, intraventricular, slow-growing benign tumors with an excellent prognosis. Currently, the molecular classification does not enhance the clinicopathologic understanding of subependymoma and myxopapillary categories. However, given the molecular advancements, this will likely change in the future. This review provides an updated molecular classification of ependymoma, discusses the individual imaging characteristics, and briefly outlines the latest targeted molecular therapies. Full Article
date Academic Neuroradiology: 2023 Update on Turnaround Time, Financial Recruitment, and Retention Strategies [CLINICAL PRACTICE] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 SUMMARY: The ASNR Neuroradiology Division Chief Working Group's 2023 survey, with responses from 62 division chiefs, provides insights into turnaround times, faculty recruitment, moonlighting opportunities, and academic funds. In emergency cases, 61% aim for a turnaround time of less than 45–60 minutes, with two-thirds meeting this expectation more than 75% of the time. For inpatient CT and MR imaging scans, 54% achieve a turnaround time of 4–8 hours, with three-quarters meeting this expectation at least 50% of the time. Outpatient scans have an expected turnaround time of 24–48 hours, which is met in 50% of cases. Faculty recruitment strategies included 35% offering sign-on bonuses, with a median of $30,000. Additionally, 23% provided bonuses to fellows during fellowship to retain them in the practice upon completion of their fellowship. Internal moonlighting opportunities for faculty were offered by 70% of divisions, with a median pay of $250 per hour. The median annual academic fund for a full-time neuroradiology faculty member was $6000, typically excluding license fees but including American College of Radiology and American Board of Radiology membership, leaving $4000 for professional expenses. This survey calls for further dialogue on adapting and innovating academic institutions to meet evolving needs in neuroradiology. Full Article
date Cardiovascular disease — risk assessment and reduction: NICE 2023 update for GPs By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 Full Article
date New Tools Take Whole-Person Approach to Obesity Care [Family Medicine Updates] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 Full Article
date PBRNs: Past, Present, and Future: A NAPCRG Report on the Practice-Based Research Network Conference. [Family Medicine Updates] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 Full Article
date Impact of Health Equity Fellowships [Family Medicine Updates] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 Full Article
date The Changing Role of a Chair and DA: Follow-Up from the 2023 ADFM Annual Conference Session [Family Medicine Updates] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 Full Article
date Guidance and Resources for Family Medicine Scholarship [Family Medicine Updates] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 Full Article
date Management of opioid use disorder: 2024 update to the national clinical practice guideline [Guideline] By www.cmaj.ca Published On :: 2024-11-11T21:05:15-08:00 Background In an evolving landscape of practices and policies, reviewing and incorporating the latest scientific evidence is necessary to ensure optimal clinical management for people with opioid use disorder. We provide a synopsis of the 2024 update of the 2018 National Guideline for the Clinical Management of Opioid Use Disorder, from the Canadian Research Initiative in Substance Matters. Methods For this update, we followed the United States Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines and used the Appraisal of Guidelines Research and Evaluation—Recommendation Excellence tool to ensure guideline quality. We carried out a comprehensive systematic literature review, capturing the relevant literature from Jan. 1, 2017, to Sept. 14, 2023. We drafted and graded recommendations according to the Grading of Recommendations, Assessments, Development and Evaluation approach. A multidisciplinary external national committee, which included people with living or lived experience of opioid use disorder, provided input that was incorporated into the guideline. Recommendations From the initial 11 recommendations in the 2018 guideline, 3 remained unchanged, and 8 were updated. Specifically, 4 recommendations were consolidated into a single revised recommendation; 1 recommendation was split into 2; another recommendation was moved to become a special consideration; and 2 recommendations were revised. Key changes have arisen from substantial evidence supporting that methadone and buprenorphine are similarly effective, particularly in reducing opioid use and adverse events, and both are now considered preferred first-line treatment options. Slow-release oral morphine is recommended as a second-line option. Psychosocial interventions can be offered as adjunctive treatment but should not be mandatory. The guideline reaffirms the importance of avoiding withdrawal management as a standalone intervention and of incorporating evidence-based harm reduction services along the continuum of care. Interpretation This guideline update presents new recommendations based on the latest literature for standardized management of opioid use disorder. The aim is to establish a robust foundation upon which provincial and territorial bodies can develop guidance for optimal care. Full Article
date Capcom Updates Its Best-Sellers List - Monster Hunter World at 20.9M, RE4 Remake at 8M, More By www.vgchartz.com Published On :: Fri, 08 Nov 2024 15:32:00 GMT Capcom has updated its list of Platinum Titles, games that have sold over one million units as of September 30, 2024. The list includes 122 games with sales over one million units, 64 over two million units, 14 over five million units, and six over 10 million units sold. Resident Evil 4 remake sold 400,000 units to bring lifetime sales to eight million units, Resident Evil 2 remake sold 300,000 units to bring sales to 14.5 million units, and Resident Evil 3 remake sold 200,000 units to bring lifetime sales to 9.2 million units. Resident Evil 7: biohazard sold 300,000 units to bring lifetime sales to 14 million units and Resident Evil Village sold 400,000 units to bring sales to 10.5 million units. Monster Hunter Rise sold 600,000 units in the quarter to bring lifetime sales to 16 million units. Monster Hunter Rise: Sunbreak sold 400,000 units to bring lifetime sales to 8.8 million units. Monster Hunter: World sold 400,000 units in the quarter to bring lifetime sales to 20.9 million units, while the Iceborne expansion sold 600,000 units for a total of 14 million units. Dragon's Dogma 2 sold 300,000 units in the quarter to bring lifetime sales to 3.3 million units. Street Fighter 6 sold 400,000 units in the quarter to bring lifetime sales to 4.1 million units. Devil May Cry 5 sold 300,000 units to bring sales to 8.7 million units. Check out the complete list below: Release Title Platform Millionunits 1 Jan 2018 Monster Hunter: World *Unit sales including Monster Hunter World: Iceborne Master Edition: 27.00 million units PS4, Xbox One, PC, DL 20.90* 2 Mar 2021 Monster Hunter Rise NSW, PS4, PS5, Xbox One, XSX, PC, DL 16.00 3 Jan 2019 Resident Evil 2 PS4, PS5, Xbox One, XSX, NSW, PC, DL 14.50 4 Jan 2017 RESIDENT EVIL 7 biohazard PS4, PS5, Xbox One, XSX, NSW, PC, DL 14.00 5 Sep 2019 Monster Hunter World: Iceborne PS4, Xbox One, PC, DL 14.00 6 May 2021 Resident Evil Village PS4, PS5, Xbox One, XSX, NSW, PC, DL 10.50 7 Mar 2009 Resident Evil 5 PS3, Xbox 360, DL 9.40 8 Oct 2012 Resident Evil 6 PS3, Xbox 360, DL 9.30 9 Apr 2020 Resident Evil 3 PS4, PS5, Xbox One, XSX, NSW, PC, DL 9.20 10 Jun 2022 Monster Hunter Rise: Sunbreak NSW, PS4, PS5, Xbox One, XSX, PC, DL 8.80 11 Mar 2019 Devil May Cry 5 PS4, Xbox One, PC, DL 8.70 12 Mar 2023 Resident Evil 4 PS4, PS5, XSX, PC, DL 8.00 13 Feb 2016 Street Fighter V PS4、PC、DL 7.70 14 Jun 1992 Street Fighter II SNES 6.30 15 Jan 1998 Resident Evil 2 PS 4.96 16 Dec 2010 Monster Hunter Freedom 3 PSP, DL 4.90 17 Mar 2017 Monster Hunter Generations Ultimate 3DS, NSW, DL 4.90 18 Nov 2014 Resident Evil PS3, DL 4.50 19 Jan 2016 Resident Evil 0: HD Remaster PS3, PS4, Xbox One, PC, DL 4.40 20 Nov 2015 Monster Hunter Generations 3DS, DL 4.30 21 Oct 2014 Monster Hunter 4 Ultimate 3DS, DL 4.20 22 Jun 2023 Street Fighter 6 PS4, PS5, XSX, PC, DL 4.10 23 Sep 2013 Monster Hunter 4 3DS, DL 4.10 24 Jul 1993 Street Fighter II Turbo SNES 4.10 25 Apr 2013 Dragon’s Dogma: Dark Arisen PS3, Xbox 360, DL 4.00 26 Mar 2008 Monster Hunter Freedom Unite PSP, DL 3.80 27 Feb 2019 Phoenix Wright: Ace Attorney Trilogy PS4, NSW, DL 3.80 28 Nov 2013 Dead Rising 3 Xbox One, DL 3.80 29 Feb 2009 Street Fighter IV PS3, Xbox 360, DL 3.60 30 Mar 2015 Resident Evil Revelations 2 PS3, PS4, Xbox 360, Xbox One, PC, DL 3.60 31 Mar 2016 Resident Evil 6 PS4, Xbox One, DL 3.50 32 Sep 1999 Resident Evil 3 Nemesis PS 3.50 33 May 2018 Street Fighter 30th Anniversary Collection PS4, Xbox One, NSW, PC, DL 3.40 34 Jun 2016 Resident Evil 5 PS4, Xbox One, DL 3.30 35 Aug 2016 Resident Evil 4 PS4, Xbox One, DL 3.30 36 Mar 2024 Dragon’s Dogma 2 PS5, XSX, DL 3.30 37 Sep 2010 Dead Rising 2 PS3, Xbox 360, PC, DL 3.20 38 Jan 2013 DmC Devil May Cry PS3, Xbox 360, DL 3.10 39 Jan 2008 Devil May Cry 4 PS3, Xbox 360, DL 3.00 40 Feb 2014 Resident Evil 4: Ultimate HD Edition PC, DL 3.00 41 Jun 2015 Devil May Cry 4 Special Edition PS4, Xbox One, DL 2.80 42 Mar 1996 Resident Evil PS 2.75 43 May 2013 Resident Evil Revelations PS3, Xbox 360, Wii U, PC, DL 2.70 44 Mar 2012 Resident Evil: Operation Raccoon City PS3, Xbox 360, DL 2.70 45 Dec 2011 Monster Hunter 3 Ultimate 3DS, DL 2.60 46 Oct 2017 Dragon’s Dogma: Dark Arisen PS4, Xbox One, DL 2.50 47 Dec 2017 Okami HD PS4, Xbox One, NSW, DL 2.50 48 Feb 2021 Capcom Arcade Stadium DL (PS4, Xbox One, NSW, PC) 2.40 49 Feb 2007 Monster Hunter Freedom 2 PSP 2.40 50 Feb 2010 Resident Evil 5: Gold Edition PS3, Xbox 360, DL 2.40 51 Jul 1999 Dino Crisis PS 2.40 52 Sep 2017 Marvel vs. Capcom: Infinite PS4, Xbox One, PC, DL 2.30 53 Dec 2005 Resident Evil 4 PS2 2.30 54 Aug 2014 Ultra Street Fighter IV PS3, Xbox 360, PC, DL 2.20 55 Feb 2011 Marvel vs. Capcom 3: Fate of Two Worlds PS3, Xbox 360 2.20 56 May 2010 Lost Planet 2 PS3, Xbox 360, DL 2.20 57 Aug 2001 Devil May Cry PS2 2.16 58 Mar 2002 Onimusha 2: Samurai’s Destiny PS2 2.10 59 Jan 2001 Onimusha: Warlords PS2 2.02 60 Jul 2021 Monster Hunter Stories 2: Wings of Ruin NSW, PS4, PC, DL 2.00 61 Mar 2017 Ultimate Marvel vs. Capcom 3 PS4, Xbox One, DL 2.00 62 May 2007 Resident Evil 4 Wii edition Wii, DL 2.00 63 Mar 2018 Devil May Cry HD Collection PS4, Xbox One, DL 2.00 64 Jun 1994 Super Street Fighter II SNES 2.00 65 Aug 2009 Monster Hunter Tri Wii 1.90 66 Oct 2018 Mega Man 11 PS4, Xbox One, NSW, DL 1.90 67 Apr 2010 Super Street Fighter IV PS3, Xbox 360, DL 1.90 68 Mar 2012 Street Fighter X Tekken PS3, Xbox 360, DL 1.90 69 Aug 2006 Dead Rising Xbox 360, DL 1.80 70 Jul 2022 Capcom Arcade 2nd Stadium DL (PS4, Xbox One, NSW, PC) 1.80 71 Dec 2006 Lost Planet Extreme Condition Xbox 360, DL 1.70 72 Nov 2013 DuckTales: Remastered PS3, Xbox 360, Wii U, DL 1.70 73 Jan 2003 Devil May Cry 2 PS2 1.70 74 Sep 1993 Street Fighter II’ Special Champion Edition MD 1.65 75 Jun 1986 Ghosts’n Goblins NES 1.64 76 Aug 2015 Mega Man Legacy Collection PS4, Xbox One, DL 1.60 77 Dec 2016 Dead Rising 4 Xbox One, PC, DL 1.60 78 Jan 2005 Resident Evil 4 GC 1.60 79 Feb 2004 Onimusha 3: Demon Siege PS2 1.52 80 Dec 1988 Mega Man 2 NES 1.51 81 Sep 2016 Dead Rising PS4, Xbox One, DL 1.50 82 Jun 2013 Remember Me PS3, Xbox 360, PC, DL 1.50 83 Nov 2017 Resident Evil Revelations Collection NSW, DL 1.50 84 Feb 2014 Strider DL（PS3, PS4, Xbox 360, Xbox One, PC） 1.50 85 Oct 2010 Dead Rising 2 Off The Record PS3, Xbox 360, DL 1.50 86 Dec 1990 Final Fight SNES 1.48 87 Dec 2003 Resident Evil Outbreak PS2 1.45 88 Mar 2001 Resident Evil Code: Veronica X PS2, DC 1.40 89 Jul 2009 Marvel vs. Capcom 2: New Age Of Heroes DL (PS3, Xbox 360) 1.40 90 Sep 2014 Dead Rising 3 Apocalypse Edition PC, DL 1.40 91 Mar 2015 DmC Devil May Cry Definitive Edition PS4, Xbox One, DL 1.40 92 Mar 2002 Resident Evil GC 1.35 93 Dec 2003 Mega Man Battle Network 4 GBA 1.35 94 Jul 2018 Mega Man X Legacy Collection PS4, Xbox One, NSW, DL 1.30 95 Jun 2009 Bionic Commando PS3, Xbox 360, PC, DL 1.30 96 May 2012 Dragon’s Dogma PS3, Xbox 360 1.30 97 Feb 2011 Super Street Fighter IV 3D Edition 3DS, DL 1.30 98 Dec 2005 Monster Hunter Freedom PSP, DL 1.30 99 Mar 2012 Resident Evil 4 DL（PS3, Xbox 360） 1.30 100 Nov 2007 Resident Evil: The Umbrella Chronicles Wii 1.30 101 Feb 2005 Devil May Cry 3 PS2 1.30 102 Nov 2002 Resident Evil 0 GC 1.25 103 Jun 2011 Super Street Fighter IV Arcade Edition PS3, Xbox 360, DL 1.20 104 Sep 2000 Dino Crisis 2 PS 1.20 105 Nov 2011 Ultimate Marvel vs. Capcom 3 PS3, Xbox 360, DL 1.20 106 Mar 2012 Devil May Cry HD Collection PS3, Xbox 360, DL 1.20 107 Apr 2019 Dragon’s Dogma DARK ARISEN NSW, DL 1.20 108 Sep 2016 Dead Rising 2 Off The Record PS4, Xbox One, DL 1.20 109 Aug 1998 Resident Evil Director’s Cut Dual Shock PS 1.20 110 Dec 1993 Mega Man X SNES 1.16 111 Feb 2000 Resident Evil Code: Veronica DC 1.14 112 Sep 1986 Commando NES 1.14 113 Sep 1997 Resident Evil Director’s Cut PS 1.13 114 Aug 2017 Resident Evil Revelations PS4, Xbox One, DL 1.10 115 Jul 2021 The Great Ace Attorney Chronicles PS4, NSW, DL 1.10 116 Oct 1991 Super Ghouls’n Ghosts SNES 1.09 117 Sep 1990 Mega Man 3 NES 1.08 118 May 1993 Final Fight 2 SNES 1.03 119 Oct 2019 Resident Evil 6 DL (NSW) 1.00 120 Dec 1998 Street Fighter Alpha 3 PS 1.00 121 Jul 2018 Megaman X Anniversary Collection 2 PS4, Xbox One, NSW, DL 1.00 122 Feb 2006 Devil May Cry 3 Special Edition PS2 1.00 A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.Full Article - https://www.vgchartz.com/article/463020/capcom-updates-its-best-sellers-list-monster-hunter-world-at-209m-re4-remake-at-8m-more/ Full Article Analysis Charts Industry
date Straftat review: an anarchic First-Person Speed dater you'll fall in love with By www.rockpapershotgun.com Published On :: Mon, 04 Nov 2024 14:30:00 +0000 It’s tempting to frame Straftat as a throwback to an older, better time for the multiplayer FPS, when the lingo was coded in frags and gibs and sucking it down, when satisfaction was drawn entirely from performance rather than some convoluted, artificial system of progression. Not only would this be inaccurate, but it would also do a disservice to what Straftat truly is, namely a wild overcorrection in response to the direction of modern multiplayer gunfests, one that careens straight through retro stations to arrive somewhere new and exciting. Read more Full Article Leonard Lemaitre Indie PC Wot I Think Lemaitre Bros Bestest Bests Shooter: First Person Sirius Lemaitre Straftat
date Enshrouded's "largest update so far" is out with a new mountain region, pets and single-player pausing By www.rockpapershotgun.com Published On :: Tue, 05 Nov 2024 18:16:08 +0000 Enshrouded has received what developers Keen Games are calling the survival game's "most sizable" update yet, sizable being an appropriate word for mountains. Expect a new playable area, the Alabaneve Summits, with its own enemies, resources, non-threatening wildlife and quests. The maximum character level has risen to 35! There are new townsfolk to find and place in your poorly built houses! You can tame animals, and make them live in poorly built houses too! You can get hypothermia! Read more Full Article RPG: Action Indie Third person Action Adventure Open World Single Player Realism Exploration Simulation Sandbox Survival & Crafting Keen Games Full product Fantasy Multiplayer Competitive Multiplayer Cooperative PC Social Enshrouded RPG
date You can now make video clips using Steam's built-in game recording feature, as an update rolls it out to all users By www.rockpapershotgun.com Published On :: Wed, 06 Nov 2024 10:23:41 +0000 Steam's built-in game recording feature has been usable in beta since the summer, but it has now been properly launched for every user, following a client update to Steam yesterday. It's basically another method of capturing funny ragdoll glitches and posting them on the "lol-games-are-dumb" channel of your friend's Discord. Or for posting that flukey knife throw in Call Of Duty to Twitter, as if you really meant to kill the man from across the map all along. Or saving a clip for your personal records, like the footage of that time you yeeted an innocent citizen off the 50-foot wall of a castle town in Dragon's Dogma 2. We all do that, right? Right? Read more Full Article Steam PC Valve
date GTA 6 release date won't slip to 2026, Take Two assure - they're "highly confident" about fall 2025 By www.rockpapershotgun.com Published On :: Thu, 07 Nov 2024 14:39:20 +0000 A few months ago, the rumour took root that GTA 6's release date would slip back from 2025 to 2026. An anonymous insider averred that studio heads were "worried" about the new open world game's progress - hence, perhaps, Rockstar's decision to mandate a full return to in-office work. Pshaw, say publishers Take-Two CEO. They announced a fall 2025 launch in March and have just doubled down on it in their latest financial briefing, with CEO Strauss Zelnick subsequently going on the tellybox to say that Take-Two are "highly confident in the timing", though he still has nothing to share about GTA 6 on PC. Read more Full Article Shooter: Third Person Grand Theft Auto 6 Rockstar Games Third person Modern Day PS5 Full product Shooter Xbox Series X/S Open World Action Adventure Single Player
date Grand Theft Auto: The Definitive Edition trilogy on PC gets a classic lighting update from the mobile version By www.rockpapershotgun.com Published On :: Tue, 12 Nov 2024 13:44:27 +0000 My strongest and most enduring memory of Grand Theft Auto will always be creasing into complete hysterics watching my mate pile into a crumpled police officer with a wooden baseball bat in GTA 3 after school one time. Young’uns these days just don’t appreciate how revolutionary it was to be able to hit a cop with a thing after he’d already fallen over. Suffice it to say I’ve got good memories of the open world series’ nascent forays into 3D, though never enough to tempt me into revisiting them, especially given the poor reception to Grand Theft Auto: The Trilogy - The Definitive Edition. I can sympathise. I’m annoyed just having to type a semicolon and a dash in the same game name. If you’re in a similarly non-fussed position (I will never not be annoyed that ‘nonplussed’ doesn’t mean what it sounds like it should mean) I can’t imagine a lighting update that’s been available on the mobile versions for a while is enough to tempt you back. But what is a reporter's job if not pathetically treading water between chunklets of Grand Theft Auto news, upon the publishing of which Graham presses the button to release the nutritious pellets on which we all wholly subsist? I hope he doesn’t read that last sentence. I don’t get my pellet if the syntax becomes too convoluted. Moving swiftly on. Read more Full Article iOS Android Grand Theft Auto: The Trilogy - The Definitive Edition Nintendo Switch Rockstar Games Third person PS5 PC Simulation RPG Shooter Action Adventure Xbox Series X/S Single Player Xbox One Racing PS4
date AI could help shrinking pool of coders keep outdated programs working By www.newscientist.com Published On :: Tue, 20 Aug 2024 16:00:28 +0100 Computer code dating back to the 1960s is still vital to banks, airlines and governments, but programmers familiar with the language are in short supply. Now AI models are being trained to fill the skills gap Full Article
date Call of Duty Black Ops 6 Season 1: Start date & time, new maps and everything you need to know By www.dailystar.co.uk Published On :: Fri, 8 Nov 2024 15:18:56 +0000 Black Ops 6 is here, and fans have been itching to know what's included in Season 1 - and now we have an answer. Here's what's included, and when you can play Full Article Gaming
date Epic Games reveals Fortnite OG release date for next month and it's permanent By www.dailystar.co.uk Published On :: Tue, 12 Nov 2024 17:31:59 +0000 Fortnite fans are going wild after Epic Games announced it's bringing back the original version of its battle royale as Fortnite OG as a permanent addition to the game. Full Article Gaming
date Updated Android malware can hijack calls you make to your bank By www.foxnews.com Published On :: Mon, 04 Nov 2024 10:00:49 -0500 An updated Android trojan called FakeCall hijacks bank calls. Tech expert Kurt “CyberGuy" Knutsson says Android phone manufacturers and Google need to step up their game on security. Full Article f9ffd891-0642-565b-baed-935600789400 fnc Fox News fox-news/tech fox-news/tech/companies/google fox-news/tech/technologies/android fox-news/tech/topics/security fox-news/tech/topics/privacy fox-news/tech/topics/cybercrime fox-news/tech article
date MonsterLabo updates The Beast fanless PC tower case By www.bit-tech.net Published On :: Mon, 25 Oct 2021 10:00:00 +0000 New design facilitates extended graphics card compatibility and customisable options. Full Article
date FDA updates Food Code for the 50 states By www.foodsafetynews.com Published On :: Fri, 08 Nov 2024 05:05:00 +0000 The U.S. Food and Drug Administration has published the 2022 Food Code Supplement. The Supplement updates the 2022 Food Code with recommendations from regulatory officials, industry, academia, and consumers at the 2023 Biennial Meeting of the Conference for Food Protection. The Food Code and its Supplement provide the government and industry with... Continue Reading Full Article Consumer Education 2022 Food Code FDA Retail Food Protection The Food Code
date Rick Scott gains new Senate endorsements out of candidate forum on eve of leader election By www.foxnews.com Published On :: Tue, 12 Nov 2024 22:07:41 -0500 Senate Republicans met on Tuesday night to hear from the three candidates to succeed Mitch McConnell, and Rick Scott left with two new endorsements. Full Article 6fb1e070-cf35-5dc6-9a29-2dd83f55001b fnc Fox News fox-news/politics fox-news/politics/senate fox-news/person/donald-trump fox-news/us/congress fox-news/politics article
date Consumers won’t be offered all three years of extended Windows 10 security updates By arstechnica.com Published On :: Thu, 31 Oct 2024 16:44:25 +0000 Home users can opt in for a single year of updates at $30 per PC—not 3 years. Full Article Tech microsoft windows 10
date Notepad.exe, now an actively maintained app, has gotten its inevitable AI update By arstechnica.com Published On :: Fri, 08 Nov 2024 13:48:19 +0000 Other Windows Insider updates include new CPU instructions for Prism x86 emulator. Full Article Tech AI microsoft notepad paint Prism windows 11 windows 11 24h2 windows insider
date Kamala Harris: What to Know About the Democratic Vice Presidential Candidate By feedproxy.google.com Published On :: Tue, 11 Aug 2020 17:22:49 PDT Read on for everything you should know about the history-making politician. [[ This is a content summary only. Visit my website for full links, other content, and more! ]] Full Article News
date UK needs to ‘update equipment’ and be ‘ready for threats we face’, says Tom Tugendhat By www.channel4.com Published On :: We spoke to the Conservative MP and former army officer Tom Tugendhat, who served in Iraq and Afghanistan. Full Article
date Breitbart Business Digest: The Trump Economic Mandate By www.breitbart.com Published On :: Wed, 13 Nov 2024 02:00:14 +0000 Donald Trump and the Republicans have a mandate for new economic policy. The post Breitbart Business Digest: The Trump Economic Mandate appeared first on Breitbart. Full Article Economy Politics Breitbart Business Digest deficit Donald Trump inflation Tariffs tax cuts
date Republican Senators Hold Leader Candidate Forum Hours Before Consequential Vote By www.breitbart.com Published On :: Wed, 13 Nov 2024 04:23:03 +0000 Republican Senators huddled for over two hours Tuesday night for a family meeting over who will take the reins from Sen. Mitch McConnell (R-KY). The post Republican Senators Hold Leader Candidate Forum Hours Before Consequential Vote appeared first on Breitbart. Full Article Politics John Cornyn John Thune Mike Lee Mitch McConnell Republicans Rick Scott Senate
date Mohammed Shami's return date announced as Gautam Gambhir, Rohit Sharma heave huge sigh of relief ahead of BGT - Hindustan Times By news.google.com Published On :: Wed, 13 Nov 2024 00:41:00 GMT Mohammed Shami's return date announced as Gautam Gambhir, Rohit Sharma heave huge sigh of relief ahead of BGT Hindustan Times"360 Days Is A...": Mohammed Shami Posts Picture From Airport. Ex-India Star Says "Brother..." NDTV SportsLive Cricket Update - GOA vs ARP Plate Group - Ranji Trophy blog: Round 5, day 1: Shami set for return in Indore ESPNcricinfoMohammed Shami makes Ranji Trophy comeback, plays first match with brother Kaif for Bengal The Indian ExpressRanji Trophy: Double delight for Mohammed Shami on comeback as brother Kaif named in Bengal playing XI ag The Times of India Full Article
date Squadron 42’s new 2026 launch date will miss its original target by 11 years By arstechnica.com Published On :: Mon, 21 Oct 2024 15:52:44 +0000 RSI said single-player Star Citizen campaign was "feature complete" a year ago. Full Article Gaming
date Dhanush, Nithya Menen’s ‘Idli Kadai’ gets a release date By www.thehindu.com Published On :: Fri, 08 Nov 2024 11:49:01 +0530 ‘Idli Kadai,’ Dhanush’s fourth directorial project, has music scored by GV Prakash Kumar Full Article Movies
date Siddharth’s next, ‘Miss You,’ gets a release date By www.thehindu.com Published On :: Fri, 08 Nov 2024 14:28:25 +0530 Starring Ashika Ranganath as the female lead, the film is directed by N Rajasekar of ‘Maapla Singam’ and ‘Kalathil Sandhippom’ fame Full Article Movies
date ‘Sikandar Ka Muqqadar’ locks premiere date on Netflix By www.thehindu.com Published On :: Fri, 08 Nov 2024 15:42:07 +0530 Starring Tamannaah Bhatia, Jimmy Shergill, and Avinash Tiwary, ‘Sikandar Ka Muqaddar’ is directed by Neeraj Pandey Full Article Movies
date RJ Balaji’s ‘Sorgavaasal’ gets a release date By www.thehindu.com Published On :: Sat, 09 Nov 2024 15:41:14 +0530 Directed by debutant Sidharth Vishwanath, ‘Sorgavaasal’ also stars Selvaraghavan, Natty, Saniya Iyappan, Sharaf-U-Dheen, Hakkim Shah, Anthonythasan, Ravi Raghavendra, and Samuel Robinson Full Article Movies
date Dead Cells’ Final Major Update 35 ‘The End Is Near’ Is Now Available on PC and Consoles, No Word on Mobile Yet By toucharcade.com Published On :: Mon, 19 Aug 2024 15:20:26 +0000 Following its announcement a few weeks ago, the final major update for Dead Cells titled The End is Near, version … Continue reading "Dead Cells’ Final Major Update 35 ‘The End Is Near’ Is Now Available on PC and Consoles, No Word on Mobile Yet" Full Article Android Apple Arcade Featured Games iPad Games iPhone games Netflix Games News Universal
date Dysmantle’s Final Major Update Is Now Live on iOS Bringing In Ark Level 4, Night Terrors, Link Towers, and Much More By toucharcade.com Published On :: Tue, 20 Aug 2024 06:04:09 +0000 Back in May, Dysmantle ($9.99) from 10tons Ltd. got its final major content update on Steam. Dysmantle version 1.4.0 titled … Continue reading "Dysmantle’s Final Major Update Is Now Live on iOS Bringing In Ark Level 4, Night Terrors, Link Towers, and Much More" Full Article Android Featured Games iPad Games iPhone games News Universal
date ‘Disney Dreamlight Valley’ Dapper Delights Update Now Available for Apple Arcade, Consoles, and PC By toucharcade.com Published On :: Wed, 21 Aug 2024 14:33:23 +0000 Last week, Gameloft announced the next major and free Disney Dreamlight Valley update for PC and consoles alongside Disney Dreamlight … Continue reading "‘Disney Dreamlight Valley’ Dapper Delights Update Now Available for Apple Arcade, Consoles, and PC" Full Article Apple Arcade Featured Games iPad Games iPhone games News Universal
date Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More By toucharcade.com Published On :: Thu, 22 Aug 2024 08:09:15 +0000 Following yesterday’s big Disney Dreamlight Valley update on Apple Arcade and other platforms, a few more notable games on Apple’s … Continue reading "Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More" Full Article Apple Arcade Featured Games iPad Games iPhone games News Universal
date ‘Company of Heroes’ Mobile Multiplayer Beta Announced for Next Week on Android, Full Update Coming to iOS and Switch As Well By toucharcade.com Published On :: Thu, 22 Aug 2024 14:19:32 +0000 Back in October last year, Feral Interactive announced that cross platform multiplayer was in the works for Company of Heroes … Continue reading "‘Company of Heroes’ Mobile Multiplayer Beta Announced for Next Week on Android, Full Update Coming to iOS and Switch As Well" Full Article Android Featured Games iPad Games iPhone games News Universal
date ‘Genshin Impact’ Version 5.0 Update Pre-Installation Now Live, New Trailer Released By toucharcade.com Published On :: Mon, 26 Aug 2024 05:37:01 +0000 HoYoverse has begun pre-installation for the major Genshin Impact (Free) version 5.0 “Flowers Resplendent on the Sun-Scorched Sojourn" update for … Continue reading "‘Genshin Impact’ Version 5.0 Update Pre-Installation Now Live, New Trailer Released" Full Article Android Featured Free Games iPad Games iPhone games News Universal
date Best iPhone Game Updates: ‘TMNT Splintered Fate’, ‘Subway Surfers’, ‘Another Eden’, and More By toucharcade.com Published On :: Mon, 26 Aug 2024 22:00:04 +0000 Hello everyone, and welcome to the week! It’s time once again for our look back at the noteworthy updates of … Continue reading "Best iPhone Game Updates: ‘TMNT Splintered Fate’, ‘Subway Surfers’, ‘Another Eden’, and More" Full Article Featured Games iPad Games iPhone games News Updates
date Capcom Updates ‘Resident Evil 4', ‘Resident Evil Village’, and ‘Resident Evil 7’ on iOS With Online DRM By toucharcade.com Published On :: Tue, 27 Aug 2024 10:53:36 +0000 Usually, updates for premium priced ports on mobile are good to have for optimization or compatibility reasons, but Capcom’s newest … Continue reading "Capcom Updates ‘Resident Evil 4', ‘Resident Evil Village’, and ‘Resident Evil 7’ on iOS With Online DRM" Full Article Featured Free Games iPad Games iPhone games News Universal
date ‘Pirates of the Caribbean: Tides of War’ Adds Cross-Server Battles in Latest Empire Invasion Update By toucharcade.com Published On :: Tue, 27 Aug 2024 21:49:41 +0000 JOYCITY has launched an exciting new update for Pirates of the Caribbean: Tides of War, inviting everyone to join in … Continue reading "‘Pirates of the Caribbean: Tides of War’ Adds Cross-Server Battles in Latest Empire Invasion Update" Full Article Featured News Sponsored Content
date ‘Genshin Impact’ Version 5.0 Update Is Now Available Worldwide on iOS, Android, PC, PS5, and More By toucharcade.com Published On :: Wed, 28 Aug 2024 04:04:18 +0000 Following pre-installation going live earlier in the week, HoYoverse has just released the major Genshin Impact (Free) version 5.0 “Flowers … Continue reading "‘Genshin Impact’ Version 5.0 Update Is Now Available Worldwide on iOS, Android, PC, PS5, and More" Full Article Android Featured Free Games iPad Games iPhone games News Universal
