SUSE/Portus version 2.2 suffers from a persistent cross site scripting vulnerability.

Researchers at Johns Hopkins University said Thursday work was ongoing at North Korean nuclear and missile sites, but no imminent threat is apparent.

AJAM reported on tribal communities and offered coverage on Indian Country that few could match

Vanessa Bryant filed a claim against the Los Angeles County Sheriff's Department, contending deputies shared unauthorized photos of the site where her husband and daughter died in a helicopter crash in January.

World Password Day advice, GoDaddy hosting accounts hacked and WordPress sites under attack. Welcome to Cyber Security Today. It’s Wednesday May 6th. I’m Howard Solomon, contributing reporter on cybersecurity for ITWorldCanada.com. Tomorrow is World Password Day. So follow safe password practices so you don’t help criminals steal data. How bad are you? Here’s are few…

Clear Blue Technologies receives $3.5 million CAD deal to build out solar-powered cell networks in the Congo, Ghana, and Nigeria

Vanessa Bryant filed a claim against the Los Angeles County Sheriff's Department, contending deputies shared unauthorized photos of the site where her husband and daughter died in a helicopter crash in January.

A long-standing mystery of how a protein displayed on the surface of malaria parasites called "TRAP" interacts with human host cells has now been found.

Are you interested to create a website but do not have any idea where to begin? Well, it is perhaps the most important facet of a website. Although functionality and content are very...

OECD CLIs point to stable growth momentum in the OECD area

Life expectancy, air quality, safety and other indicators of well-being can vary dramatically within countries, depending on which region you live in. Looking beyond national averages is vital to get an accurate picture of quality of life and to guide local government policy.

Safeguarding people’s health and the environment through responsible marketing and use of pesticides in agriculture relies on regulation, and compliance with this regulation. OECD have launched an online resource to help regulators in different countries share their experiences and best practice and to act as a portal for information on pesticide compliance and enforcement.

Integrated Pest Management (IPM) in agriculture is high on the agenda in many countries. IPM is about promoting the sustainable use of pesticides in the context of challenges including climate change, increasing demand for food, feed and fibres and pest resistance. OECD has launched the IPM Hub, an online focal point for information on Integrated Pest Management.

This website gives information about the regulatory approaches adopted by OECD member countries to mitigate pesticide risks to insect pollinators. Following a survey of OECD member countries, it was concluded that mitigation of risks to insect pollinators is important to all its member countries, and that mitigation is a critical component of balancing the benefits of plant protection products with potential risks to insect pollinators.

Several dozen gathered at the intersection of 62nd Street and Michigan Road in Indianapolis on Saturday, where a police officer fatally shot Dreasjon 'Sean' Reed, 21, on Wednesday.

Driving Licence Apply Ltd is paying to appear at the top of searches for terms including 'DVLA licence' and 'driving licence apply'. It charges £77.60 for a replacement driving licence.

With people looking to reduce monthly outgoings during the lockdown, one cut back is to declare a car as SORN to avoid tax and insurance costs - however, drivers are being urged not to pay to do so.

केंद्रीय उड्डयन मंत्री हरदीप सिंह पुरी के विदेश में फंसे भारतीयों को वापस लाने के बयान के बाद नागरिक उड्डयन मंत्रालय की वेबसाइट क्रैश हो गई। केंद्रीय मंत्री के बयान के बाद लाखों की संख्या में लोगों ने वेबसाइट पर विजिट

MINI has discontinued the Clubman model in the Indian market. The company has also unlisted the Clubman for their website. Before it was unlisted from their website, MINI had launched the Clubman Indian Summer Red Edition in the country during February this year.

Indian Motorcycles unveiled the FTR Carbon globally a few days ago. The FTR Carbon is now the flagship model in the FTR range and as the name suggests, the motorcycle gets a bunch of new carbon fibre body panels. As far

More than 86,000 people worldwide have been infected with the novel coronavirus and the global death toll is nearing 3,000.To try to prevent the spread of the virus, local governments have been closing tourist attractions that normally draw large crowds. World-famous destinations such as the Great Wall of China and the Venetian canals resemble ghost towns.As new coronavirus cases are confirmed daily, more closures and cancellations are expected. For the most up-to-date information on the status of an attraction or event, check the institution's or event's main web page.

Yesterday, Mike Taylor raised a very interesting question on Twitter: “Anybody know what Safari 5 requires for a page to be Reader-ifiable?”

Website launched

‘Proper opportunities would be created for their livelihood’

Seeking to return home, workers protest at under-construction site

A neutron crystallographic study of perdeuterated transthyretin reveals important aspects of the structure relating to its stability and its propensity to form fibrils, as well as evidence of a single water molecule that affects the symmetry of the two binding pockets.

Biggest tremor on record at Little Plumpton site forces halt to fracking in Lancashire  Lancashire Evening Post

London soil pollution worst on former Blitz bomb sites  Chemistry World

UK's only active fracking site near Blackpool records largest ever earth tremor as homeowners complain of windows shaking  iNews

Largest tremor yet detected at Lancashire fracking site  ITV News

For Heusler-type Ni–Mn–Ga ferromagnetic shape-memory alloys, the configuration of the martensite variants is a decisive factor in achieving a large magnetic shape-memory effect through field-induced variant reorientation. Based upon the spatially resolved electron backscatter diffraction technique, the microstructural evolution associated with the martensitic transformation from austenite to seven-layered modulated (7M) martensite was investigated on a polycrystalline Ni53Mn22Ga25 alloy. It was clearly shown that grain interior nucleation led to the formation of diamond-shaped 7M martensite within the parent austenite matrix. This diamond microstructure underwent further growth through an isotropic expansion with the coordinated outward movement of four side habit planes, followed by an anisotropic elongation with the forward extension of a type-I twin pair. A two-step growth model is proposed to describe the specific morphology and crystallography of 7M martensite. In addition, the habit planes were revealed to possess a stepped structure, with the {1 0 1}A plane as the terrace and the {0 1 0}A plane as the step. The characteristic combination of martensite variants and the underlying mechanism of self-accommodation in the martensitic transformation have been analysed in terms of the minimum total transformation strain, where the deformation gradient matrix was constructed according to the experimentally determined orientation relationship between the two phases. The present results may deepen the understanding of special martensite microstructures during the martensitic transformation in ferromagnetic shape-memory alloys.

Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor. This approach circumvents two major issues: the inherent experimental difficulties in working with a membrane-bound ion channel and the complication that a heteromeric assembly is necessary to create a key, physiologically relevant binding site. Residues that form the orthosteric site in a highly stable ortholog, acetylcholine-binding protein, were selected for substitution. Recombinant proteins were prepared and characterized in stepwise fashion exploiting a range of biophysical techniques, including X-ray crystallography, married to the use of selected chemical probes. The decision making and development of the surrogate, which is termed a glycine-binding protein, are described, and comparisons are provided with wild-type and homomeric systems that establish features of molecular recognition in the binding site and the confidence that the system is suited for use in early-stage drug discovery targeting a heteromeric α/β glycine receptor.

Malaria is a devastating disease caused by a protozoan parasite. It affects over 300 million individuals and results in over 400 000 deaths annually, most of whom are young children under the age of five. Hexokinase, the first enzyme in glucose metabolism, plays an important role in the infection process and represents a promising target for therapeutic intervention. Here, cryo-EM structures of two conformational states of Plasmodium vivax hexokinase (PvHK) are reported at resolutions of ∼3 Å. It is shown that unlike other known hexokinase structures, PvHK displays a unique tetrameric organization (∼220 kDa) that can exist in either open or closed quaternary conformational states. Despite the resemblance of the active site of PvHK to its mammalian counterparts, this tetrameric organization is distinct from that of human hexokinases, providing a foundation for the structure-guided design of parasite-selective antimalarial drugs.

The section of the Bilbao Crystallographic Server (http://www.cryst.ehu.es) dedicated to subperiodic groups includes a new tool called LSITESYM for the study of materials with layer and multilayer symmetry. This new program, based on the site-symmetry approach, establishes the symmetry relations between localized and extended crystal states using representations of layer groups. The efficiency and utility of the program LSITESYM is demonstrated by illustrative examples, which include the analysis of phonon symmetry in Aurivillius compounds and in van der Waals layered crystals MoS2 and WS2.

Should global warming cause sea levels to rise as predicted in coming decades, thousands of archaeological sites in coastal areas around the world will be lost to erosion. With no hope of saving all of these sites, three archaeologists—Leslie Reeder of Southern Methodist University, Jon Erlandson of the University of Oregon and Torben Rick from the Smithsonian's National Museum of Natural History—have issued a call to action for scientists to assess the sites most at risk around the world.

The post Scientists issue call to action for archaeological sites threatened by rising seas, urban development appeared first on Smithsonian Insider.

Collecting trips for Charles Doolittle Walcott (1850-1927), paleontologist and fourth Secretary of the Smithsonian Institution, were often a family affair. This 1910 photograph shows their […]

The post Charles Doolittle Walcott (1850-1927) family campsite in the Canadian Rockies appeared first on Smithsonian Insider.

An excavation at a site in South Africa has unearthed the 190-million-year-old dinosaur nesting site of the prosauropod dinosaur Massospondylus–revealing significant clues about the evolution of complex reproductive behavior in early dinosaurs.

The post 190-million-year-old dinosaur nesting site discovered in South Africa appeared first on Smithsonian Insider.

Smithsonian Secretary Wayne Clough, left, talks with Carlos Jaramillo, scientist at the Smithsonian Tropical Research Institute in Panama, at a research site near the Panama […]

The post Wayne Clough & Carlos Jaramillo, at a research site near the Panama Canal. appeared first on Smithsonian Insider.

One such parasite lurks in Chesapeake Bay: an invasive barnacle that hijacks a mud crab’s reproductive system and impregnates it with parasite larvae—even if the crab is male.

The post Undersea parasite turns male mud crabs female appeared first on Smithsonian Insider.

This image of a wild giant panda was taken by a trail camera in a remote forest in central China. As few as 1,600 giant […]

The post A wild giant panda from the Website Smithsonian Wild appeared first on Smithsonian Insider.

A newly-discovered species of ant supports a controversial theory of species formation. The ant, known to live only under a single eucalyptus tree on the […]

The post Deadbeat ant species branched off as parasite inside its own colony appeared first on Smithsonian Insider.

Have you ever had a pet that seemed just a little bit crazy or odd? Can you be sure that it was in control of […]

The post Crazy eyes and mind control – the power of parasites appeared first on Smithsonian Insider.

Through sheer coincidence, two Smithsonian researchers at the National Zoological Park have discovered that 18 percent of the white-tailed deer population in the Eastern United […]

The post Smithsonian study reveals white-tailed deer in eastern U.S. are infected with a malaria parasite appeared first on Smithsonian Insider.

The outer membrane of Gram-negative bacteria is highly impermeable to hydrophilic molecules of larger than 600 Da, protecting these bacteria from toxins present in the environment. In order to transport nutrients across this impermeable membrane, Gram-negative bacteria utilize a diverse family of outer-membrane proteins called TonB-dependent transporters. The majority of the members of this family transport iron-containing substrates. However, it is becoming increasingly clear that TonB-dependent transporters target chemically diverse substrates. In this work, the structure and phylogenetic distribution of the TonB-dependent transporter YncD are investigated. It is shown that while YncD is present in some enteropathogens, including Escherichia coli and Salmonella spp., it is also widespread in Gammaproteobacteria and Betaproteobacteria of environmental origin. The structure of YncD was determined, showing that despite a distant evolutionary relationship, it shares structural features with the ferric citrate transporter FecA, including a compact positively charged substrate-binding site. Despite these shared features, it is shown that YncD does not contribute to the growth of E. coli in pure culture under iron-limiting conditions or with ferric citrate as an iron source. Previous studies of transcriptional regulation in E. coli show that YncD is not induced under iron-limiting conditions and is unresponsive to the ferric uptake regulator (Fur). These observations, combined with the data presented here, suggest that YncD is not responsible for the transport of an iron-containing substrate.