mi LTIMindtree expands footprint in US with new innovation facility By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:04:02 +0530 Full Article
mi A multifunctional “three-in-one” fluorescent theranostic system for hepatic ischemia–reperfusion injury By pubs.rsc.org Published On :: Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC04962D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jihong Liu, Dongni Yin, Wen Zhang, Xin Wang, Tony D. James, Ping Li, Bo TangA single-component multifunctional fluorescent theranostic system (MB-Gly) for use during hepatic ischemia-reperfusion injury (HIRI) has been developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Phase transition induced hydrogen activation for enhanced furfural reductive amination over CoCu bimetallic catalyst By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05885B, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yilin Wei, Zixu Ma, Beibei Liu, Jialin Yang, Dan Wu, Yongsheng Zhang, Yuexing Zhang, Charles Chunbao Xu, Renfeng NieThe synthesis of primary amines from renewable biomass and its derivatives through reductive amination has garnered significant attention. How to construct efficient non-noble-metal catalysts that enable low-temperature catalysis still remains...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06202G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu FangAbstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi India's CO2 emissions account 8pc of global total, to rise by 4.6pc in 2024: Report By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:34:02 +0530 Full Article
mi There will be census in country but not based on caste: Union Minister Shobha Karandlaje By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:18:02 +0530 Full Article
mi Union Education Minister Dharmendra Pradhan urges states to support exam reforms for zero-error entrance test By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:22:01 +0530 Full Article
mi Akashteer: Transforming India's air defence with cutting-edge technology By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:26:02 +0530 Full Article
mi Union Jal Shakti Minister CR Paatil chairs 13th high-powered review meeting of Brahmaputra Board By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:34:02 +0530 Full Article
mi DRDO conducts maiden flight test of Long-Range Land Attack Cruise Missile (LRLACM) By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:44:02 +0530 Full Article
mi COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article Environment
mi Indonesia and Australia hold joint military drills after signing a new defense agreement By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:32:15 +0530 The Indonesian and Australian militaries are holding joint combat drills off Indonesia’s main island of Java with about 2,000 troops training in air, maritime, amphibious and land operations Full Article World
mi Chemical synthetic approaches to mimic the TRAIL: promising cancer therapeutics By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3639-3651DOI: 10.1039/D4MD00183D, Review ArticleAbdullah-Al Masum, Shin Aoki, Md. Mahbubur Rahman, Yosuke HisamatsuTRAIL induced apoptosis signalling by death receptors (DR4/DR5).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3652-3673DOI: 10.1039/D4MD00425F, Review ArticleSemim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra BorahMetabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3795-3799DOI: 10.1039/D4MD00458B, Research ArticleKazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki TamaokiA photoswitchable centromere-associated protein E (CENP-E) inhibitor based on the 4-methylaminoazobenzene photoswitch is reported, which is characterized with cis–trans photoisomerization with blue-green light and fast thermal relaxation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3837-3852DOI: 10.1039/D4MD00426D, Research ArticleAbdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. BednarskiStructure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safetyThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3800-3816DOI: 10.1039/D4MD00585F, Research ArticleMarwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-KarmalawyNovel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3746-3758DOI: 10.1039/D4MD00122B, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong LiWe designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Supreme Court stays order for CBI probe into sexual assault of minor in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:07:47 +0530 Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre Full Article Tamil Nadu
mi IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
mi AIADMK will not form an alliance with BJP in 2026 polls, reiterates Palaniswami By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:30:55 +0530 “During the Lok Sabha election, it was said at the party headquarters and in press bytes that the AIADMK will not have alliance with the BJP in the [2026] Assembly election,” he said Full Article Tamil Nadu
mi Tamil Nadu CM Stalin to launch Phase II of nutritional intervention programme for malnourished children, mothers By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:48 +0530 Mothers of over 76,700 babies in the age group of zero to six months, identified as malnourished, would be covered under Phase II of the programme Full Article Tamil Nadu
mi T.N. govt. to take a call on verifying criminal antecedents before appointing schoolteachers By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:15:58 +0530 It also assures Madras High Court of putting in place an effective complaint redressal mechanism in the interest of school students Full Article Tamil Nadu
mi Four Swedish companies, including IKEA, looking to set up base in Tamil Nadu: Swedish Ambassador to India By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:56:01 +0530 There are 70 Swedish companies in Tamil Nadu, employing about 25,000 people. But we want to do more, says Jan Thesleff Full Article Tamil Nadu
mi SBI, HDFC Bank, ICICI Bank figure in RBI’s 2024 list of Domestic Systemically Important Banks (D-SIBs) By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:00:14 +0530 Higher D-SIB surcharge fixed for SBI and HDFC Bank, will be applicable from April 01, 2025 Full Article Business
mi Centre’s nod sought for Vizag Metro, MA&UD Minister informs A.P. Assembly By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:55:45 +0530 The revised cost estimate stands at ₹17,232 crore; the project is initially proposed to come up in two phases with four corridors spanning a total length of 76 km Full Article Andhra Pradesh
mi Andhra Pradesh Govt. weighing options on how to utilise Mahila Samrakshana Karyadarshis, says Home Minister By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:30:46 +0530 Ambiguity in overall control of their duties and service matters resulted in immense distress for the MSKs, says Home Minister Full Article Andhra Pradesh
mi Andhra Pradesh govt. reaffirms commitment to ‘irrigating every acre of farmland’ in State through river-interlinking projects By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:43:13 +0530 Full Article Andhra Pradesh
mi Varun Hospitality announces eco-friendly mixed-use project to replace The Gateway Hotel in Visakhapatnam By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:31 +0530 Full Article Andhra Pradesh
mi India’s office leasing soars 41% in 2024 amid rent hikes, supply crunch, and GCC growth: Cushman & Wakefield By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:20:06 +0530 In an interview to businessline, Cushman & Wakefield’s Veera talks about commercial space leasing outlook, trends, and rental and supply trends for the coming months Full Article Real Estate
mi Ensuring full occupancy at IT towers in Tier-II cities focus: Telangana IT Minister By www.thehindu.com Published On :: Wed, 13 Nov 2024 10:48:49 +0530 Godavarikhani near Ramagundam, Mancherial among locations likely to get facilities for IT firms Full Article Telangana
mi Missile Exhibition Centre inaugurated at DRDL By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:10:16 +0530 Full Article Telangana
mi Affordable generics will stay relevant amid a premiumisation trend: Bhushan Akshikar By www.thehindu.com Published On :: Wed, 13 Nov 2024 10:50:51 +0530 GSK will keep its existing portfolios while entering areas like oncology, said company officials at its centenary celebrations Full Article Health
mi COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article World
mi Millions of Nigerians go hungry as floods compound hardship By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:07:00 +0530 Torrential rains and floods in 29 of Nigeria's 36 states this year have destroyed more than 1.5 million hectares of cropland, affecting more than nine million people Full Article Environment
mi Synthesis of MOF-supported Pt catalyst with high electrochemical oxidation activity for methanol oxidation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36370-36377DOI: 10.1039/D4RA06393G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Merve Akin, Hatice Kars, Muhammed Bekmezci, Aysenur Aygun, Mert Gul, Guray Kaya, Fatih SenIn this study, Pt and Pt@Ti-MOF NPs catalysts were synthesized by chemical reduction method. Ti-MOF structure was synthesized using the solvothermal method, and the effect of Ti-MOF on methanol oxidation was investigated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mi Karnataka Chief Minister Siddaramaiah says no proposal to ease night traffic ban through Bandipur By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:45:12 +0530 Deputy Chief Minister D.K. Shivakumar had stated, in Wayanad in Kerala, that the government would take all possible measures to lift night traffic ban through Bandipur, which had riled wildlife conservationists in Karnataka Full Article Karnataka
mi Karnataka High Court dismisses Union Bank of India’s petition seeking transfer of Valmiki corporation case to CBI By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:28:26 +0530 ‘Banking Regulations Act does not empower banks to seek transfer of probe into criminal cases registered by States to agency of its choice’ Full Article Karnataka
mi Watch | War over Waqf: Busting myth and misinformation By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:25:12 +0530 How did an incident in a small village in Vijayapura snowball into an issue of national interest? Full Article Karnataka
mi KEA opposes fee reduction for recruitment examinations in Karnataka By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:47:00 +0530 Points out that the government does not provide any grant for conducting recruitment examinations Full Article Karnataka
mi Three youths go missing after coracle overturns in Sharavathi backwaters in Sagar taluk By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:01:17 +0530 Full Article Karnataka
mi I've found ways and means to break it down: Ashwin on Smith's batting By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:21:04 +0530 The two seasoned campaigners would face off during the Border-Gavaskar Trophy starting November 22 in Perth Full Article Cricket
mi Shambala and Kimiko impress By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:34:17 +0530 Full Article Races
mi Comeback man Shami hogs the spotlight as MP takes honours on opening day against Bengal By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:38:38 +0530 Full Article Sport
mi Ranji Trophy | Tamil Nadu has Railways under the cosh with dominant show By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:18:55 +0530 CRICKET | Skipper Jagadeesan’s decision to field pays off handsomely as Ajith Ram and Gurjapneet take quick wickets; Ahuja, Saif and Merai hold out with half centuries Full Article Cricket
mi India's middle class tightens its belt, squeezed by food inflation By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:50:09 +0530 Slowing urban spending over the past three to four months has not only hurt the earnings of largest consumer goods firms Full Article Economy
mi Ennoventure bags $8.9 million in Series A led by Tanglin Venture Partners By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 10:50:10 +0530 The round included participation from existing investors, such as Fenice Investment Group and additional SAFE investors Full Article Companies