The Biden administration has failed to win the strategic competition with China through ineffective policies toward Beijing, the senior Republican on the Senate Foreign Relations Committee said this week.

Sauber has signed 20-year-old Brazilian driver Gabriel Bortoleto to make his debut in Formula 1 next year as Nico Hulkenberg's teammate.

“Go out there, represent the Red Sox, and become a challenge to the Yankees.”

The post What a Yankees fan recently told Pedro Martinez that became ‘personal’ appeared first on Boston.com.

"Some men dream of fortunes. Others dream of cookies." This is a real fortune cookie fortune. It would be a prescient fortune for Yongsik Lee. He invented the fully automatic fortune cookie machine in the early 1980s and built a business on his invention. The Korean immigrant sold fortune cookie machines and fortunes to companies all over the US. It was a good business until one day, one of his employees stole his fortunes and his customers. We get to the bottom of a theft that forever changed Yongsik Lee's life.

(Image: Fortune cookies on display at The Ritz Carlton in Miami Beach, Florida. Credit: Neilson Barnard/Getty Images)

In the early 2000’s the US helped fund Afghanistan's first private university. It was part of an effort to help rebuild Afghanistan's education system. Over time, the American University of Afghanistan has become a symbol of hope for many young Afghan men and women who dream about higher education. But that very hope has also made those students, and their campus in Kabul, targets for extremists.

Also: First Lieutenant, Erica MacSwan, prepares for her deployment to Afghanistan; Lt. MacSwan recalls her family’s personal experience with the 9/11 attacks; and we step inside a fashion boutique in the heart of Kabul.

(Two years after the attack on the American University in Kabul, school officials have stepped up security. That means the campus has the look and feel of a military compound. Credit: Farzanah Wahidy/PRI)

Toluene – often used in paint, metal cleaners and adhesives – is a clear, colorless liquid that vaporizes when exposed to air at room temperature. According to OSHA, it also has a sharp and sweet smell, which is a sign of exposure.

Boca Raton, FL — Retail workers “are being asked to do too much,” and many are “leaving or throwing up their hands,” says a researcher from Florida Atlantic University.

Geneva, Switzerland — Workers exposed to the sun’s ultraviolet rays account for nearly a third of all non-melanoma skin cancer deaths, according to the results of a recent study.

Toronto — Instead of having a zero-tolerance policy on cannabis use, employers may want to consider “minimum wait periods before a work shift when cannabis consumption is not allowed,” researchers say.

Toluene is a clear and colorless liquid that turns to vapor when exposed to air at room temperature. According to OSHA, it’s often used in a mixture with other solvents and chemicals, such as paint pigments, so employees who work with paint, metal cleaners and adhesives may be at risk for exposure.

The Waypoint 300 is a rechargeable high-lumen pistol-grip spotlight with enhanced down-range lighting capability. Featuring 270,000 candela, a 1,039-meter beam distance and 1,000 lumens on high, the spotlight’s powerful long-range targeting beam is portable and runs for 3.75 to 87 hours on high, medium and low, respectively.

Chicago — One out of 5 workers who take a leave of absence to care for others later take leave for a medical condition of their own, results of a new analysis show.

Over time, the body loses the ability to produce the enzyme (lactose) that digests the carbohydrate in dairy foods, causing bloating, gas, and sometimes diarrhea. Taking a lactase enzyme (Lactaid tablets) when you drink milk or eat dairy foods, will usually prevent symptoms of lactose intolerance. A food sensitivity, on the other hand, can produce symptoms that are unrelated to food allergies or intolerances.

If you’ve been following this controversy surrounding erythritol, don’t panic yet. Check in first with David Feder, Executive Editor—Technical for Prepared Foods as he provides some reasoned opinion on the matter.

Phytolon, a biotechnology company that offers natural food colors via fermentation-based technologies, and Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, announced the successful completion of the first development milestone of their multi-product collaboration to produce natural food colors and the resulting distribution of an equity milestone to Ginkgo.

Designed for manufacturing environments where dust-producing products can create an explosive atmosphere, the cETLus-certified systems adhere to construction standards and fulfill the requirements for Class II, Division 2 Hazardous locations.

Mohawk Builder + Multifamily is building a more sustainable world with a diverse portfolio of carpet, laminated wood and resilient flooring all made in the USA to help customers create greener communities.

Designed to meet the demands of challenging applications in packaged products, the X52’s proprietary software seamlessly transitions between single energy, dual energy or both modes.

The post Stolen Pride: Loss, Shame, and the Rise of the Right was curated by information for practice.

Now you can wear your brutally honest love for architecture on your wrist with the B/1 watch by Toledano & Chan inspired by Marcel Breuer's NYC landmark.

Writer Stacia Tolman worked for many years as a high school English teacher at a private school in New Hampshire’s Monadnock region.

A pair of ruby slippers worn by Judy Garland in “The Wizard of Oz” is on the auction block nearly two decades after a thief stole the iconic shoes, convinced they were adorned with real jewels.

Actor John Rhys-Davies narrates a reimagined audio drama of "A Christmas Carol," drawn by the story’s themes of transformation, compassion and redemption, which he likens to the journeys of both Scrooge and his Rings character, Gimli, as they overcome prejudice and open their hearts to others.

The Russians love to win. Unfortunately, other countries often take advantage of our victories, whereas we easily forget about our military prowess. Today, during the Eastern Economic Forum in Vladivostok, few people in Russia may remember that it was the Soviet army that put an end to the worst war in the history of mankind - World War II, or the Great Patriotic War, as it is known in Russia. It was on September 3rd, when it happened.  September 3rd is the official date of the end of World War II in the Soviet Union. It used to be celebrated as a non-working day and had been officially called the National Day of Victory over Imperialist Japan until 1947. One can still find posters at history museums in the Far East of Russia that say: Victory Day over Japan - September 3rd. The day of September 3rd was officially approved as the red date of the calendar by the decree from the Presidium of the Supreme Soviet of the USSR of September 2, 1945. USSR's first and, unfortunately, the only parade of victory over Japan took place on September 16, on the territory of Harbin, where the Chinese still take care of Soviet burials.

The title compound, [RuGa2Cl6(C7H8)(CO)2] or [(CO)2(GaCl2)(η6-toluene)Ru]+[GaCl4]−, was isolated from the reaction of Ga2Cl4 with di­phenyl­silanediol in toluene, followed by the addition of Ru3(CO)12. The compound contains a ruthenium–gallium metal–metal bond with a length of 2.4575 (2) Å.

A confiscated package of street drugs was characterized by the usual mass spectral (MS) and FT–IR analyses. The confiscated powder material was highly crystalline and was found to consist of two very different species, accidentally of sizes convenient for X-ray diffraction. Thus, one each was selected and redundant com­plete sets of data were collected at 100 K using Cu Kα radiation. The selected crystals contained: (a) 1,2-diphenyl-2-(pyrrolidin-1-yl)ethanone hy­dro­chloride hemihydrate or 1-(2-oxo-1,2-di­phenyl­eth­yl)pyrrolidin-1-ium chloride hemihydrate, C18H20NO+·Cl−·0.5H2O, (I), a synthetic cathinone called `α-D2PV', and (b) the sugar myo-inositol, C6H12O6, (II), probably the only instance in which the drug and its diluent have been fully characterized from a single confiscated sample. Moreover, the structural details of both are rather attractive showing: (i) inter­esting hydrogen bonding observed in pairwise inter­actions by the drug mol­ecules, mediated by the chloride counter-anions and the waters of crystallization, and (ii) π–π inter­actions in the case of the phenyl rings of the drug which are of two different types, namely, π–π stacking and edge-to-π. Finally, the inositol crystallizes with Z' = 2 and the resulting diastereoisomers were examined by overlay techniques.

Eukaryotic TIR (Toll/interleukin-1 receptor protein) domains signal via TIR–TIR interactions, either by self-association or by interaction with other TIR domains. In mammals, TIR domains are found in Toll-like receptors (TLRs) and cytoplasmic adaptor proteins involved in pro-inflammatory signaling. Previous work revealed that the MAL TIR domain (MALTIR) nucleates the assembly of MyD88TIR into crystalline arrays in vitro. A microcrystal electron diffraction (MicroED) structure of the MyD88TIR assembly has previously been solved, revealing a two-stranded higher-order assembly of TIR domains. In this work, it is demonstrated that the TIR domain of TLR2, which is reported to signal as a heterodimer with either TLR1 or TLR6, induces the formation of crystalline higher-order assemblies of MyD88TIR in vitro, whereas TLR1TIR and TLR6TIR do not. Using an improved data-collection protocol, the MicroED structure of TLR2TIR-induced MyD88TIR microcrystals was determined at a higher resolution (2.85 Å) and with higher completeness (89%) compared with the previous structure of the MALTIR-induced MyD88TIR assembly. Both assemblies exhibit conformational differences in several areas that are important for signaling (for example the BB loop and CD loop) compared with their monomeric structures. These data suggest that TLR2TIR and MALTIR interact with MyD88 in an analogous manner during signaling, nucleating MyD88TIR assemblies uni­directionally.

A pressure-induced triclinic-to-monoclinic phase transition has been caught `in the act' over a wider series of high-pressure synchrotron diffraction experiments conducted on a large, photoluminescent organo-gold(I) compound. Here, we describe the mechanism of this single-crystal-to-single-crystal phase transition, the onset of which occurs at ∼0.6 GPa, and we report a high-quality structure of the new monoclinic phase, refined using aspherical atomic scattering factors. Our case illustrates how conducting a fast series of diffraction experiments, enabled by modern equipment at synchrotron facilities, can lead to overestimation of the actual pressure of a phase transition due to slow transformation kinetics.

In the title compound, C25H25NO7S, the mol­ecular conformation is stabilized by intra­molecular O—H⋯O and N—H⋯O hydrogen bonds, which form S(6) and S(8) ring motifs, respectively. The mol­ecules are bent at the S atom with a C—SO2—NH—C torsion angle of −70.86 (11)°. In the crystal, mol­ecules are linked by C—H⋯O and N—H⋯O hydrogen bonds, forming mol­ecular layers parallel to the (100) plane. C—H⋯π inter­actions are observed between these layers.

The neutral organosilicon(IV) complex, (C6F5)2Si(OPO)2 (OPO = 1-oxopyridin-2-one, C5H4NO2), was synthesized from (C6F5)2Si(OCH3)2 and 2 equiv. of 1-hy­droxy­pyridin-2-one in tetra­hydro­furan (THF). Single crystals grown from the diffusion of n-pentane into a THF solution were identified as a THF hemisolvate and an n-pentane hemisolvate, (C6F5)2Si(OPO)2·0.5THF·0.5C5H12 (1). p-Tol­yl2Si(OPO)2 (2) and mesit­yl2Si(OPO)2 (3) crystallized directly from reaction mixtures of 2 equiv. of Me3Si(OPO) with p-tol­yl2SiCl2 and mesit­yl2SiCl2, respectively, in aceto­nitrile. The oxygen-bonded carbon and nitro­gen atoms of the OPO ligands in 1, 2, and 3 were modeled as disordered indicating co-crystallization of up to three possible diastereomers in each. Solution NMR studies support the presence of exclusively the all-cis isomer in 1 and multiple isomers in 2. Poor solubility of 3 limited its characterization in solution.

When reacted in dry, degassed toluene, [Ir(COD)Cl]2 (COD = cyclo­octa-1,5-diene) and 2 equivalents of 2-(di-tert-butyl­phosphinito)anthra­quinone (tBuPOAQH) were found to form a unique tri-iridium compound consisting of one monoanionic dinuclear tri-μ-chlorido complex bearing one bidentate tBuPOAQ ligand per iridium, which was charge-balanced by an outer sphere [Ir(toluene)(COD)]+ ion, the structure of which has not previously been reported. This product, which is a toluene solvate, namely, (η2:η2-cyclo­octa-1,5-diene)(η6-toluene)­iridium(I) tri-μ-chlorido-bis­({3-[(di-tert-butyl­phosphan­yl)­oxy]-9,10-dioxoanthracen-2-yl}hydridoiridium(III)) toluene monosolvate, [Ir(C7H8)(C8H12)][Ir2H2(C22H24O3P)2Cl3]·C7H8 or [Ir(toluene)(COD)][Ir(κ-P,C-tBuPOAQ)(H)]2(μ-Cl)3]·toluene, formed as small orange platelets at room temperature, crystallizing in the triclinic space group Poverline{1}. The cation and anion are linked via weak C—H⋯O inter­actions. The stronger inter­molecular attractions are likely the offset parallel π–π inter­actions, which occur between the toluene ligands of pairs of inverted cations and between pairs of inverted anthra­quinone moieties, the latter of which are capped by toluene solvate mol­ecules, making for π-stacks of four mol­ecules each. The related ligand, 2-(di-tert-butyl­phosphinometh­yl)-anthra­quinone (tBuPCAQH), did not form crystals suitable for X-ray diffraction under analogous reaction conditions. However, when the reaction was conducted in chloro­form, yellow needles readily formed following addition of 1 atm of carbon monoxide. Diffraction studies revealed a neutral, dinuclear, di-μ-chlorido complex, di-μ-chlorido-bis­(carbon­yl{3-[(di-tert-butyl­phosphan­yl)­oxy]-9,10-dioxoanthracen-2-yl}hydridoiridium(I)), [Ir2H2(C23H26O2P)2Cl2(CO)2] or [Ir(κ-P,C-tBuPCAQ)(H)(CO)(μ-Cl)]2, Ir2C48H54Cl2O6P2, again crystallizing in space group Poverline{1}. Offset parallel π–π inter­actions between anthra­quinone groups of adjacent mol­ecules link the mol­ecules in one dimension.