Bob Iaccino, Path Trading Partners

Todd Colvin, Ambrosino Brothers

Todd Colvin, Ambrosino Brothers

Bob Iaccino, Path Trading Partners

Larry Shover, Efficient Advisors

Todd Colvin, Ambrosino Brothers

Bob Iaccino, Path Trading Partners

Larry Shover, Efficient Advisors

Bob Iaccino, Path Trading Partners

Larry Shover, Efficient Advisors

Todd Colvin, Ambrosino Brothers

Bob Iaccino, Path Trading Partners

Dan Deming, KKM Financial

Bob Iaccino, Path Trading Partners

Larry Shover, Efficient Advisors

Todd Colvin, Ambrosino Brothers

How Music Therapists Helped A Mother Connect With The Newborn She Still Hasn’t Met  Houston Public Media

Bengaluru's all-woman music collective Metronome to release a track for Mother's Day  Times of India

5 Dance Moves Made Popular By Salman Khan Which Prove Sometimes Even ‘Pappu Can Dance Saala’  MensXP.com

Tennis courts in Vancouver, along with several other Metro Vancouver municipalities, will be open this weekend as municipalities across Metro Vancouver lift restrictions put in place in March due to the COVID-19 crisis. There are rules for getting out to play, however.

There's no question that COVID-19 has uprooted the lives of people across Metro Vancouver and around the world. Data can be one way to show how, exactly, the pandemic has changed the way we move and operate in our daily lives.  

The eerie inhumanity of Donald Trump.

An OM team has a rare opportunity to share the Gospel with the Doma people at the funeral of a senior member of the community.

The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements in proteomics methods have enabled quantitative studies to attain better resolution. Here we introduce methods to undertake global analyses of gene expression through RNA and protein quantification in Xenopus embryos and tissues.

Determining the concentration of protein samples generally is accomplished either by measuring the UV absorbance at 280 nm or by reacting the protein quantitatively with dyes and/or metal ions (Bradford, Lowry, or BCA assays). For purified proteins, UV absorbance remains the most popular method because it is fast, convenient, and reproducible; it does not consume the protein; and it requires no additional reagents, standards, or incubations. No method of protein concentration determination is perfect because each is subject to a different set of constraints such as interference of buffer components and contaminating proteins in direct UV determination (A₂₈₀) or reactivity of individual proteins and buffer components with the detecting reagents in colorimetric assays. In cases in which protein concentration is critical (e.g., determination of catalytic rate constants for an enzyme), it may be advisable to compare the results of several assays.

The post Using SOLIDWORKS Sheet Metal for Cardboard Packaging Design appeared first on SOLIDWORKS Education Blog.

One of the main mechanisms of azole resistance of Aspergillus fumigatus is thought to be a reduction in the drug’s affinity for the target molecule, Cyp51A, due to its amino acid mutation(s). It is known that the azole resistance pattern is closely related to the mutation site(s) of the molecule. In this study, we tried to develop a simple and rapid detection method for cyp51A mutations using the endonuclease Surveyor nuclease. The Surveyor nuclease assay was verified using several azole-resistant strains of A. fumigatus that possess point mutations in Cyp51A. For validation of the Surveyor nuclease assay, blind tests were conducted using 48 strains of A. fumigatus (17 azole-resistant and 31 azole-susceptible strains). The Surveyor nuclease assay could rapidly detect cyp51A mutations with one primer set. Also, all the tested strains harboring different cyp51A single point mutations could be clearly distinguished from the wild type. The Surveyor nuclease assay is a simple method that can detect cyp51A mutations rapidly.

As per the normal review of market volatility to ensure adequate collateral coverage, the Chicago Mercantile Exchange Inc., Clearing House Risk Management staff approved the performance bond requirements for the following products listed in the advisory at the link below.

The rates will be effective after the close of business on 4/24/2020.

Click here for the full text of the advisory

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As per the normal review of market volatility to ensure adequate collateral coverage, the Chicago Mercantile Exchange Inc., Clearing House Risk Management staff approved the performance bond requirements for the following products listed in the advisory in the link below. Please email any questions to Clearing.RiskManagement@cmegroup.com

The rates will be effective after the close of business on Friday, April 24, 2020.

For the full text of this advisory, please click here.

CME will be updating liquidity parameters for Interest Rate Swap contracts denominated in BRL and MXN. These changes only impact portfolios with larger BRL or MXN exposures. For MXN, the impact to liquidity add-on is approx. 5-10% for portfolios with aggregated DV01 above 100M+ DV01 in local currency. For BRL, the impact to liquidity add-on is 30%+ for portfolios with aggregated DV01 above 10M+ in local currency. Based on current exposures, CME Clearing expects that there will be no impact to existing portfolios at this time. These changes will be available for testing in our New Release environment April 29, 2020, with a production date of May 4, 2020.

Click here for the full text of the advisory

20-181

As per the normal review of market volatility to ensure adequate collateral coverage, the Chicago Mercantile Exchange Inc., Clearing House Risk Management staff approved the performance bond requirements for the following products listed in the advisory at the link below.

The rates will be effective after the close of business on 05/01/2020.

Click here for the full text of the advisory

20-183

As per the normal review of market volatility to ensure adequate collateral coverage, the Chicago Mercantile Exchange Inc., Clearing House Risk Management staff approved the performance bond requirements for the following products listed in the advisory at the link below. Please email any questions to Clearing.RiskManagement@cmegroup.com

The rates will be effective after the close of business on Friday, May 1, 2020.

For the full text of this advisory, please click here.

As per the normal review of market volatility to ensure adequate collateral coverage, the Chicago Mercantile Exchange Inc., Clearing House Risk Management staff approved the performance bond requirements for the following products listed in the advisory at the link below. Please email any questions to Clearing.RiskManagement@cmegroup.com

The rates will be effective after the close of business on Friday, May 8, 2020.

For the full text of this advisory, please click here.

The post An Electrical Engineer Using Sheet Metal? appeared first on The SOLIDWORKS Blog.

Madagascar’s recent elections marked an ostensible return to democracy, but unless the new government works hard to implement meaningful political, economic and social reforms, the prospect of further crisis is just a matter of time.

By Father Dave Pivonka, TOR

“This is the time of fulfillment.”

Those are the first words Jesus speaks to us in the Gospel of Mark. For 14 verses, he says nothing. He meets John the Baptist, the Holy Spirit descends upon him, and he faces temptation in the wilderness. But through it all, he doesn’t say a word. Then, finally, Jesus speaks: “This is the time of fulfillment. The kingdom of God is at hand. Repent, and believe in the gospel” (Mark 1:15).

The temptation, for most of us, is to hear those words in the past tense. We hear them as something Jesus said long ago to Jewish people in Roman-occupied Galilee.

But that’s not how the Scriptures work. They’re not simply a record of things that were said 2,000 years ago. They’re not a collection of history books like we find at our local library. They are “living and active, sharper than any two-edged sword . . . and discerning the thoughts and intentions of the heart” (Heb. 4:12).

This means Scripture speaks to us today. Jesus speaks to us today. Right here. Right now. This is the time of fulfillment. This is the time Jesus invites us to know him and follow him and encounter the Kingdom of Heaven. But he doesn’t just invite us. In Mark 1:15, he also tells us how we answer that invitation: “Repent, and believe.”

The Greek word used there for “repent and believe” is metanoia. It implies a turning or a change of mind. So, what Jesus says is, “Turn away from sin, and turn toward me. Change your focus—from sin, from the world, from a culture of distraction—and focus on me instead.” Ultimately, he issues a call to conversion, a call to a new way of thinking and a new way of living. And he issues that call, not just to Peter, James, John, and the rest of the 12, but to you and me.

Which means the question for us is: how do we answer that call? How, here and now, do we repent and believe? How do we experience metanoia?

Last year, the team from 4PM Media and I attempted to answer that question, when we spent 17 days in the Holy Land, filming Metanoia, a new 10-part video series on conversion and discipleship.

But the trip turned out to be much more than that.

Shot on location in some of our faith’s most sacred places, including the Sea of Galilee, the River Jordan, and the desert of temptations, Metanoia invites viewers to an encounter with Christ in both Scripture and history. It also invites each of us to look deep into our hearts, so we can hear how Christ is calling us to conversion.

For many Catholics, it’s tempting to think of conversion as a once and done event. It’s equally tempting to think of it as something other people need: that Jesus is calling other people to repent and believe—“those bishops and priests” or “those people who are in serious sin”—but not us. No, we think, it’s those people who need conversion. Never us. But in reality, it is always us.

Every one of us struggles in some way to live the Gospel. Every one of us has some area of our life that we have not handed over to Jesus. Every one of us, to some extent, bears some responsibility for the problems in the Church and world today.

That’s why conversion is a process each and every one of us must continually enter into. It’s a lifelong journey of being transformed by Christ and conformed to Christ. It’s never done. At least, not until we see Jesus face to face and hear the words, “Well done, good and faithful servant.”

And so, over the course of 10 weeks, Metanoia will invite Catholics to become the witness the world needs us to be and the disciples Jesus calls us to be. It does that by asking us to look at different areas of our life and faith—from our understanding of who Christ is and what it means to pray, to how we approach the Church’s more challenging teachings. It then invites us to think and pray about how Jesus calls us to conversion in those areas.

The whole series is really one big invitation to let God into every aspect of our life and transform it all.

Metanoia launches on Monday, February 3. Episodes will be available to watch at wildgoose.tv. I hope you join us. Because this is the time of fulfillment. Jesus is here. He has something for us right now. But we will never experience it if we don’t repent and believe. We will never experience it without metanoia.

Nicola Sturgeon won plaudits from some unlikely quarters this week for her “grown-up conversation” on lifting the lockdown.

Theatre

New findings on a state initiative in Wisconsin suggest that to make the most out of smaller class sizes in the early grades, teachers should focus on basic skills when they have one-on-one contact with students, ask children to discuss and demonstrate what they know, and have a firm, but nurturing,

Most states take a very hands-off approach to regulating home schooling, and some advocates worry that makes it attractive to neglectful and abusive parents.

Little is known about the pharmacokinetics and required dosage of metronidazole in preterm neonates.

In this study the pharmacokinetics of metronidazole in preterm neonates was investigated by measurement of the drug in dried blood-spot samples. A dosage regimen is proposed that should result in more appropriate, less frequent dosing in the most preterm neonates. (Read the full article)

Few epidemiological studies, which included varied exposure assessment, have investigated the relation between drinking-water–disinfection byproducts such as trihalomethanes and hypospadias, and their results have been inconclusive.

Little evidence was found for an association between trihalomethanes and hypospadias, but a novel association between water consumption and hypospadias was found. Factors that influence maternal water consumption, or other contaminants in tap or bottled water, might explain this finding. (Read the full article)

Cardiovascular risk factors predict the development of premature atherosclerosis. As the number of risk factors increases, so does the extent of these lesions. Assessment of cardiovascular risk factors is an accepted practice in adults but is not used in pediatrics.

In this study, the authors discuss how the presence of ≥2 cardiovascular risk factors is associated with vascular changes in adolescents. The findings were compared with the Patholobiological Determinants of Atherosclerosis in Youth risk score to demonstrate that a simple method of clustering is a reliable tool to use in clinical practice. (Read the full article)

Associations between short sleep duration, obesity, and metabolic dysfunction have been proposed for children but have not been explored appropriately.

The main findings included a nonlinear trend between sleep duration and body weight and the finding that children's sleep averaged 8 hours per night regardless of body weight. Lower sleep duration values were strongly associated with increased metabolic risk. (Read the full article)

Predischarge serum or transcutaneous bilirubinometry (TcB) measurements are recommended as appropriate screening options for identifying infants at risk for neonatal hyperbilirubinemia (NH). Visual inspection for jaundice is not reliable at identifying infants with NH in the community.

When compared with visual inspection alone, coordinated TcB screening for NH in acute-care and community settings is associated with significant improvements in laboratory utilization, patient care, convenience, and safety. (Read the full article)

Recent studies have called into question the benefit of perioperative corticosteroids in children undergoing heart surgery, but have been limited by small sample size, the lack of placebo control, and the grouping of various steroid regimens together in analysis.

We evaluated outcomes across methylprednisolone regimens versus no steroids in a large cohort of neonates and found no mortality or length-of-stay benefit associated with any regimen, and a higher risk of infection in certain subgroups. (Read the full article)

There is a perception among clinicians that methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and/or meningitis result in a greater burden of disease than invasive infections attributed to methicillin-susceptible Staphylococcus aureus (MSSA) among very low birth weight (VLBW) infants.

VLBW infants with MRSA and MSSA bacteremia and/or meningitis have equivalent morbidity and mortality. These findings suggest that allocation of resources for prevention and treatment of both MRSA and MSSA infections among VLBW infants should be comparable. (Read the full article)

Changes in BMI category appear to be common in young children and are associated with cardiometabolic risk in cross-sectional studies. However, there are few longitudinal studies and little information from multiethnic samples of US middle school children.

Findings demonstrate that shifts in BMI category are common in middle-school-aged children and associated with clinically meaningful changes in cardiometabolic risk factors. Programs to promote decreases in BMI, prevent increases, and moderate risk are indicated. (Read the full article)