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Andhra Pradesh Chief Minister lays foundation for three renewable energy projects with a total capacity of 5,314MW

A JV pact was also signed by the State power corporation and the National Hydropower Corporation for two pumped storage hydropower projects




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INS Vikrant with a crew strength of about 1,700 Navy personnel arrives in Chennai




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Ludhiana woman raped after her brother elopes with accused's daughter

A man along with three family members allegedly gang-raped a woman after his daughter eloped with the victim's brother; they also recorded the act on their mobile phones




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Tripura's connectivity project with Bangladesh may be delayed: Minister

Opening of Agartala-Akhaura rail link and Maitree bridge got further delayed due to the political turmoil and change in government in Bangladesh; this project was inaugurated by Prime Minister Narendra Modi and then Bangladesh PM Sheikh Hasina in 2023




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Regret standing with BJP during protest by farmers, says Dushyant Chautala

JJP leader says it was a mistake that he did not understand farmers’ sentiments but that he does not regret allying with the BJP in 2019




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Chess | India’s young talent could do better with more sponsorship and government support




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Raja wins men’s 61kg with record lifts




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Approach is to treat every game with utmost respect: Gukesh




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Women’s Indian Open golf | Manon De Roey jumps to joint lead with Alice Hewson

The Belgian carves out seven birdies to be on par with the ever-so-consistent Alice Hewson of England




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Under-23 World Wrestling Championships: Chirag Chikkara clinches gold as India shines with nine medals

Chirag Chikkara becomes the second Indian man, after Paris Olympics bronze medallist Aman Sehrawat, to win the gold at the U23 Championships.




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Mauritius holds election with cost of living on everyone's minds

Mauritius parliamentary election: Economic promises, alliances, and voter expectations in the Indian Ocean archipelago




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Iranian charged for plotting Trump assassination tasked with targeting Israeli tourists in Sri Lanka: U.S authority

Shakeri is an Islamic Revolutionary Guard Corps (IRGC) asset, remains at large and is believed to reside in Tehran, Iran




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Soldier with Yemen's exiled government opens fire, killing two Saudi troops, wounding another

Police in the area published pictures of the soldier, saying there was a 30-million-Yemeni-rial reward for information leading to the soldier's arrest




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North Korea ratifies mutual defence treaty with Russia

The report came amid international criticism over increasing military cooperation between the two countries, with North Korea having sent tens of thousands of troops to Russia to support its war against Ukraine




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Largest city in the U.S. with Arab-majority backs Trump

In Dearborn, where nearly half of the 1,10,000 residents are of Arab descent, Vice-President Kamala Harris received over 2,500 fewer votes than Mr. Trump




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Andhra Pradesh CM Chandrababu Naidu to lead high-level meeting with State officials on streamlining Governance

The CM Chandrababu Naidu’s agenda includes setting priorities for development goals, guiding the administrative machinery on the state government’s objectives, and outlining a strategic framework titled “Ten Principles for Development.”




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Andhra Pradesh sets ambitious goals with Drone Policy 4.0

Approved by Council of Ministers, the policy aims to secure Rs. 1,000 crore in investments, generate employment for 40,000 people and create 25,000 skilled drone pilots; vision hinges on a planned 300-acre drone city at Orvakal in Kurnool district, the first-of-its-kind in the country




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Weak dependence [electronic resource] : with examples and applications / by Jérôme Dedecker, Paul Doukhan, Gabriel Lang, León R. José Rafael, Sana Louhichi, Clémentine Prieur

New York, NY : Springer New York, 2007




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Insights from data with R [electronic resource] : an introduction for the life and environmental sciences / Owen L. Petchey, Andrew P. Beckerman, Natalie Cooper, Dylan Z. Childs.

Oxford : Oxford University Press, 2021.




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Practical data analysis with JMP [electronic resource] / Robert Carver.

Cary, NC : SAS Institute, 2019.




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A step-by-step guide to exploratory factor analysis with SPSS [electronic resource] / Marley W. Watkins.

New York, NY : Routledge, 2021.




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Diverse thermal desorption combined with self-aspirating corona discharge ionization for direct mass spectrometry analysis of complex samples

Anal. Methods, 2024, 16,2071-2076
DOI: 10.1039/D4AY00200H, Paper
Qinhao Shi, Xiaohua Yu, Shuang Sun, Weilong Wu, Wenyan Shi, Quan Yu
The thermal desorption (TD) technique is widely employed in modern mass spectrometry to facilitate the detection of non-volatile analytes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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PCB-C4D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00198B, Paper
Mingpeng Yang, Mingyi Cao, Zhixuan Zhang, Chaofan Wang
A solution conductivity detection method, using PCB-C4D coupled with paper-based microfluidic sampling, has been proposed for the rapid and in situ analysis of raw solution with particle filtration, improving detection consistency and reliability.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Analysis of O-acetylated sialic acids by 3-nitrophenylhydrazine derivatization combined with LC-MS/MS

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00330F, Paper
Chenhao Zhao, Xingdan Wang, Jing Wu, Yeli Hu, Qiwei Zhang, Qi Zheng
The 3-NPH-labeled sialic acids produce a high abundance of reporter ions, which can improve the accuracy of quantitative analysis of O-acetylated species.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A Multimode Biosensor Based on Prussian Blue Nanoparticle Loaded with Gold Nanoclusters for the Detection of Aflatoxin B1

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02330C, Paper
zhaodi Fu, juan Huang, Wei Wei, zhihui Wu, Xingbo Shi
Herein, a novel fluorescent/colorimetric/photothermal biosensor is proposed for aflatoxin B1 (AFB1) detection in food based on Prussian blue nanoparticles (PBNPs) (~50 nm), gold nanocluster (AuNCs) and aptamer (Apt) within three...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Field method for preservation of total mercury in waters, including those associated with artisanal scale gold mining

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02216A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
David C. P. King, Michael J. Watts, Elliott M. Hamilton, Robert J. G. Mortimer, Mike Coffey, Odipo Osano, Maureene Auma Ondayo, Marcello Di Bonito
A method was developed for sampling and preserving total Hg from water samples, recovering >75% Hg over 4 weeks of storage. The method was assessed using water samples at artisanal gold mining sites in Kenya.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ag-coated tetrapod gold nanostars (Au@AgNSs) for acetamiprid determination in tea using SERS combined with microfluidics

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00297K, Paper
Qian Ke, Limei Yin, Heera Jayan, Hesham R. El-Seedi, Xiaobo Zou, Zhiming Guo
The combination of highly sensitive SERS substrate core–shell Au@AgNSs and microfluidic chip featuring four circular split hybrid structures were used for quantitative detection of acetamiprid in tea. The LOD of acetamiprid was 0.048 ng mL−1.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Resolving phytosterols in microalgae using offline two-dimensional reversed phase liquid chromatography-supercritical fluid chromatography coupled with quadrupole time-of-flight mass spectrometry

Anal. Methods, 2024, 16,2278-2285
DOI: 10.1039/D3AY02261G, Paper
Magali Batteau, Elodie Bouju, Adriana Ramirez-Romero, Sylvie Nuccio, René De Vaumas, Florian Delrue, Karine Faure
Development of an off-line LC-SFc-MS method, separation of sterol isomers in algal unsaponifiable fractions, elution pattern helping in the reduction of structural candidates.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A novel fluorescent probe with a large Stokes shift for colorimetric and selective detection of cysteine in water, milk, cucumber, pear and tomato

Anal. Methods, 2024, 16,2322-2329
DOI: 10.1039/D3AY02322B, Paper
Lin Luo, Ranran Guo, Lianjie Wang, Xixi Song, Zhao Wang, Junliang Wu
A novel fluorescent probe for colorimetric and selective detection of cysteine was efficiently constructed through a simple and mild reaction conditions. Probe 2 displays a linear response to Cys concentrations (0–30 μM), low detection limit (0.89 μM), large Stoke shift (125 nm).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Direct solid sample analysis of low-cost jewelry using spectroanalytical techniques: exploratory chemical data evaluation and metal migration with synthetic sweat

Anal. Methods, 2024, 16,2286-2291
DOI: 10.1039/D4AY00325J, Paper
Thaila Lorena de Araújo, Fabiola Manhas Verbi Pereira, Edenir Rodrigues Pereira-Filho
Jewelry samples were directly analyzed using LIBS and XRF.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples

Anal. Methods, 2024, 16,2330-2339
DOI: 10.1039/D3AY02271D, Paper
Hong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan Liu
Fatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Analysing micro- and nanoplastics with cutting-edge infrared spectroscopy techniques: a critical review

Anal. Methods, 2024, 16,2177-2197
DOI: 10.1039/D3AY01808C, Critical Review
Open Access
Junhao Xie, Aoife Gowen, Wei Xu, Junli Xu
In this review, we discussed and compared the applications of Fourier transform infrared spectroscopy, quantum cascade laser infrared spectroscopy, atomic force microscopy-based infrared spectroscopy, and optical photothermal infrared spectroscopy in MNP research from multiple perspectives.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A new colorimetric aptasensor for paraquat detection based on the designed aptamer with multiple paraquat binding sites in combination with gold nanoparticles

Anal. Methods, 2024, 16,2340-2348
DOI: 10.1039/D4AY00053F, Paper
Pakawat Kongpreecha, Sineenat Siri
Given paraquat's environmental health risks, there is a need for a fast and simple detection method. This study presents a novel colorimetric aptasensor with a tailored aptamer, boosting sensitivity by targeting multiple paraquat binding sites.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00264D, Paper
Mariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia Doss
Fabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Three-dimensional hotspot structures constructed from nanoporous gold with a V-cavity and gold nanoparticles for surface-enhanced Raman scattering

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00348A, Paper
Yang Xu, Yan Wu, Jianjun Wei, Yuanyu Zhao, Peili Xue
A nanoporous gold V-shaped resonant cavity (NPGVRC) structure constructed with plasmonic resonance coupling effect. The NPGVRC has excellent SERS performance and 3D hotspot properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02200E, Paper
Qiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan Gao
Tuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Solutions and Tools for Dealing with Broken Links in Web Pages

A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down.

I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links.

The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs.



  • HTML5
  • Web Design Articles

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Fading in a Page on Load with CSS & JavaScript

When I visit a page, I get annoyed when I try to interact with elements while the website is still loading. Often stuff is moving around, fonts aren’t quite loaded, and it feels broken.

I know nowadays we’re obsessed in this industry with gaining every millisecond in page performance. But in a couple of projects that I recently overhauled, I added a subtle and clean loading mechanism that I think makes the experience nicer, even if it does ultimately slightly delay the time that the user is able to start interacting with my page.

The post Fading in a Page on Load with CSS & JavaScript appeared first on Impressive Webs.




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Detecting Specific Text Input with HTML and CSS

Recently I came across a CodePen demo by a developer/engineer named Jane that was Tweeted out by Šime Vidas. The demo has a neat collection of HTML and CSS tricks rolled into one that I thought was worth examining in detail.

The page displays a secret message based on specific text input. Ok, that’s no big deal, right? Well this is done using pure HTML and CSS – no JavaScript. I’ve seen stuff like this before, but I thought it would be cool to break down exactly how this works. There are a few notable things happening in the code so I’ll break down each of the parts.

The post Detecting Specific Text Input with HTML and CSS appeared first on Impressive Webs.




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​Rogue state: On Israel’s conflict with Hezbollah  

Israel is choosing war over peace, escalation over compromise 




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The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif

RSC Med. Chem., 2024, 15,3576-3596
DOI: 10.1039/D4MD00438H, Research Article
Ruolin Cao, Fangyu Du, Zhiqiang Liu, Pengcheng Cai, Minggang Qi, Wei Xiao, Xuefei Bao, Guoliang Chen
Rho-associated coiled-coil containing kinase (ROCK) plays an important role in inflammation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation

RSC Med. Chem., 2024, 15,3529-3557
DOI: 10.1039/D4MD00481G, Research Article
Mohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai Adel
Discovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rationally modified SNX-class Hsp90 inhibitors disrupt extracellular fibronectin assembly without intracellular Hsp90 activity

RSC Med. Chem., 2024, 15,3609-3615
DOI: 10.1039/D4MD00501E, Research Article
Open Access
Gciniwe S. Mathenjwa, Abir Chakraborty, Abantika Chakraborty, Ronel Muller, Mathew P. Akerman, Moira L. Bode, Adrienne L. Edkins, Clinton G. L. Veale
Rationally modified Hsp90 inhibitors which retained of on-target activity but showed no engagement of intracellular Hsp90, or stimulation of the heat shock response, were found to significantly alter the extracellular fibronectin network.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis, and evaluation of benzhydrylpiperazine-based novel dual COX-2/5-LOX inhibitors with anti-inflammatory and anti-cancer activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00471J, Research Article
Poorvi Saraf, Bhagwati Bhardwaj, Akash Verma, Mohammad Aquib Siddiqui, Himanshu Verma, Pradeep Kumar, Samridhi Srivastava, Sairam Krishnamurthy, Saripella Srikrishna, Sushant Kumar Shrivastava
Screening piperazine derivatives via ChEMBL database led to the design and synthesis of novel dual COX-2/5-LOX inhibitors with strong anti-inflammatory, analgesic, and anti-cancer activity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design and Synthesis of coumarin-based amphoteric antimicrobials with the biofilm interference and immunoregulation effects

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00721B, Research Article
Qun Tang, Haiyang Zhang, Kasemsiri Chandarajoti, Zirui Jiao, Lianhua Nie, Sai Lv, Jiakun Zuo, Wen Zhou, Xiangan Han
Bacterial infections pose a threat to the health of animals and human being, and the biofilm formation exacerbates the microbial threat. New antimicrobial agents to address this challenge are much...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Human microbiome derived synthetic antimicrobial peptides with activity against Gram-negative, Gram-positive, and antibiotic resistant bacteria

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00383G, Research Article
Open Access
Walaa K. Mousa, Ashif Y. Shaikh, Rose Ghemrawi, Mohammed Aldulaimi, Aya Al Ali, Nour Sammani, Mostafa Khair, Mohamed I. Helal, Farah Al-Marzooq, Emilia Oueis
An AMP-derived short 15-mer peptide and its cyclic derivatives have low micromolar broad spectrum antibacterial activity, with rapid onset of bactericidal effect and a membrane-targeting mode of action.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00742E, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek Wimmer
A series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00617H, Research Article
Aida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü Beydemir
In this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Continuous flow synthesis of N,N-dimethyltryptamine (DMT) analogues with therapeutic potential

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00562G, Research Article
Open Access
Andreas Simoens, Andreas Dejaegere, Marthe Vandevelde, Christian V. Stevens
Flow chemistry allows for the rapid and clean synthesis of therapeutically relevant tryptamines in good yields, including the large scale drug rizatriptan.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00555D, Research Article
Shenghua Gao, Letian Song, Bing Ye, Mianling Yang, Junyi Li, Manyu Gu, Ann E. Tollefson, Karoly Toth, Peng Zhan, Xinyong Liu
The continuous mutational nature of SARS-CoV-2 and its inter-species' similarities emphasize the urgent need to design and develop more direct-acting antiviral agents against highly infectious variants.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry