JSW Energy Ltd., based in Mumbai, India, is refinancing about US$1.1 billion via a 5:25 financial structure for its hydropower-related debt following the purchase of two hydroelectric projects in November 2014 from Jaiprakash Power Ventures Ltd.  

JSW Energy Ltd., based in Mumbai, India, is refinancing about US$1.1 billion via a 5:25 financial structure for its hydropower-related debt following the purchase of two hydroelectric projects in November 2014 from Jaiprakash Power Ventures Ltd.  

Manitoba Hydro has announced that it will eliminate more than 15% of its workforce while raising rates by at least 10% as the provincial utility's efforts to cut expenditures continue.

Presentation by Don Ball of Chemcut Corporation

Candidates may now take online remote proctored exams right from the comfort of your own home. Dave Hernandez, vice president of education, answers questions about this new option from IPC EDGE. Why remote proctoring? In this time of shelter-in-place, IPC wanted to find a way for students to obtain or renew IPC certification remotely. We […]

Bonds backing clean energy and other sustainable initiatives are booming. Investors are snapping up green bonds at the fastest pace on record, as big banks like Morgan Stanley and Bank of America Corp. pile in with new issuance to feed the growing appetite for socially responsible investments.

This is another important Scottish Sheriff Court case on the competency of an assignation of standard securities (secured charges).  It follows two recent conflicting cases of OneSavings Bank v Burns, where the court found in favour of the borr...

The Government has published advice on meeting the regulatory requirement to obtain a valid Energy Performance Certificate (“EPC”) prior to marketing a property during the Coronavirus outbreak. By way of reminder, the Energy Performance ...

Kavesseri Menon and Beena Menon –v- Nathan Pask and Rosalind Goode (as joint fixed charge Receivers) [2019] EWHC 2611(ch) Summary: The High Court recently provided much needed clarity on the previously unanswered question of whether Receivers ...

Even in COVID-19 times, companies (and their directors) should not unnecessarily jeopardise the rights of their creditors and the continuity of their activities. Think about paying dividends, and making unnecessary costs, despite the financial probl...

The stay on debt collection proceedings will end on 22 April 2020. The Federal government adopted emergency law on 16 April 2020, in order to prevent coronavirus-related bankruptcies and the resulting job losses. The “COVID-19 Insolvency Ordin...

A close look at the evidence suggests that China has not been engaged in “debt-trap diplomacy” in the Pacific, at least not so far. Nonetheless, if future Chinese lending continues on a business-as-usual basis, serious problems of debt sustainability will arise, and concerns about quality and corruption are valid. By Jonathan Pryke HONOLULU (March 2, 2020)—In an atmosphere of heightened geostrategic competition, China’s Belt and Road Initiative (BRI) has raised questions about the risk of debt problems in less-developed countries. Such risks are especially worrying for the small and fragile economies of the Pacific.

This is a summary only. Click the title for the full article, or visit www.EastWestCenter.org/Research-Wire for more.

Galatians 4:19–20

“Can N40 billion be stolen when it did not exist? Is the payment of staff salaries and benefits, an act of corruption?" an official argues.

The post Alleged Fraud: We spent N22 bn on ‘salaries, services, debts’ — NDDC appeared first on Premium Times Nigeria.

The household debt balance has rapidly increased to approach 1,400 trillion won (US$1.24 trillion) as of the end of June this year. It is estimated the balance may have surpassed the 1,400-trillion-won level by mid-August. As the amount of household debt reaches 90 percent of the gross domestic products (1,637 trillion won at the end of last year), economists began warning the high debt level may pose an obstacle to further growth.According to the Bank of Korea on August 23, the balance of house...

When the economic situation deteriorates, when the financial situation becomes strained, when the granting of credit becomes more difficult, being able to provide effective collateral in order to obtain cash from lenders is more important than ever ...

  Pursuant to Article 3:246 paragraph 1 of the Dutch Civil Code (DCC) pledgees have the power to enforce their right of pledge on receivables by claiming (direct) payment of the receivable. This power also includes the right to enforce rights o...

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Key Points A disposition by a receiver, whether appointed by the court or under a fixed charge, is not a disposition by a mortgagor for the purposes of s284 Insolvency Act 1986 (“IA”). The wider implications of the decision may be to lim...

In light of the recent market events, the trading prices of many loans have fallen dramatically. As a result, companies (or their private equity sponsors) may consider utilising the debt buy-back mechanics in their credit agreements. A debt buy-back...

On April 17, the Alberto Ángel Fernández administration in Argentina officially unveiled its offer for debt restructuring on USD 66 billion foreign currency-denominated bonds. Starting on that date, the offer is valid for 20 days, a period during which difficult negotiations with bondholders are expected to take place. Based on the first reactions from some […]

The post Argentina’s Debt Restructuring “Groundhog Day”… or Maybe Not? Three Key Points appeared first on Inter Press Service.

A more equitable and fair society, able to conquer the effects of pandemics, starts with debt-free education and skills development

The post Young people need a bailout: Cancel student debt held by national banks appeared first on The Mail & Guardian.

A.L. Sadler examines in minute detail the origins of tea drinking and the rich and complex components of its ritualization.

Legal proceedings have been launched in Switzerland against Britain’s Prince Andrew and his ex-wife Sarah, a newspaper reported on Thursday, over money they were said to still owe on a luxury chalet.Queen Elizabeth’s second son and Sarah, who remain close despite their 1996 divorce, bought the plush holiday home in the Verbier ski resort in southwest Switzerland in 2014 for 22 million Swiss francs (US$21.7 million).The wooden chalet has seven bedrooms, an indoor swimming pool and a sauna, Le…

The world’s poorer nations, reeling under an unrelenting attack on their fragile economies by the COVID-19 pandemic, have suffered an equally deadly body blow: being buried under heavy debt burdens. Abiy Ahmed, prime minister of Ethiopia who was awarded the Nobel Peace Prize in 2019, said last week that in 2019, 64 countries, nearly half […]

The post World’s Poor Hit by Double Jeopardy: a Deadly Virus & a Devastating Debt Burden appeared first on Inter Press Service.

A high level of external debt is linked with decreased economic growth but there are policy options that can help economies keep growing.

Asia’s economies have generally maintained sound macroeconomic policies that can help the region withstand this latest challenge and emerge even stronger.

Bank-held nonperforming loans in some Asian economies have risen in recent years. Policy makers should address this growing risk now.

The pandemic provides an opportunity for regional financial cooperation on reforms to make Asian banks more resilient to crises.

The webinar will highlight the important role the MDBs are called to play in closing the SOGI data gap by supporting innovative forms of data generation and evidence-based policymaking in their countries.

WASHINGTON: Some debts were not sustainable and needed to be restructured, re-profiled or written off, International Monetary Fund (IMF) Managing Director Kristalina Georgieva said in an interview recorded earlier this week.

In this interview to ITV News, Ms Georgieva also urged governments to spend more money on health workers to protect the most vulnerable.

“There is a possibility that in some cases debt simply is not sustainable and therefore some action has to be taken either to re-profile or restructure or in some cases write off this debt,” she said.

Although G20 countries have promised some debt relief, a transcript of the interview, released by the IMF headquarters in Washington, indicated that Ms Georgieva believed the crisis required them to go further.

Imran has argued that heavy debt burdens are preventing countries from focusing on the challenge of saving people from pandemic as well as hunger

Last month, Prime Minister Imran Khan appealed to the leaders of rich countries, the UN secretary general and heads of financial institutions to give debt relief to developing countries like Pakistan so that they could combat the deadly Covid-19 in a better way.

The prime minister argued that heavy debt burdens were preventing some countries from focusing on the real challenge of saving their people from the deadly pandemic and hunger that extended lockdowns would trigger.

The IMF chief, while acknowledging the need to restructuring loans, also said the first priority was to combat the disease that has already killed hundreds of thousands and infected several millions across the globe.

“The only thing we ask countries is please spend more money for your doctors and nurses — and please, please use the money to protect the most vulnerable,” she said.

The interviewer, Julie Etchingham, noted that loans usually came with conditions — such as tightening public spending — that were difficult to implement during the Covid-19 crisis.

Ms Georgieva said she was aware of the risks ahead for the IMF. “We are looking to the transparency and accountability in countries. They themselves are coming up with commitments to audit the use of the funds we provide, but there are no strings attached,” she said.

The IMF chief said that more than 100 countries had reached out to them for help to fight the pandemic and 50+ requests were swiftly approved for a total of about $18 billion.

Asked to assess the scale of the crisis facing the global economy, Ms Georgieva did not mince her words. “It is the worst crisis since the Great Depression. But it is more than that because it is a combination of a health crisis and an economic shock,” she said. “And it is truly global.”

The IMF now has about $1 trillion dollars lending capacity — four times more than in the last financial crisis.

The IMF approved $1.386 billion of assistance for Pakistan under the Rapid Financing Instrument to address the economic impact of the Covid-19 shock.

Published in Dawn, May 9th, 2020

NORTHRIDGE, Calif.—HARMAN Professional Solutions, the global leader in audio, video, lighting and control systems, today announced new JBL Professional One Series 104-BT and 104-BTW desktop reference monitors with Bluetooth will be making their debut at...

NORTHRIDGE, Calif.—HARMAN Professional Solutions, the global leader in audio, video, lighting and control systems, today announced new AKG K361-BT and K371-BT professional studio headphones featuring Bluetooth connectivity at the 2020 NAMM show in...

Was wäre, wenn Kopfhörer Stimmungen erkennen und die Musikauswahl ihrer Nutzer automatisch individuell daran anpassen könnten? Wie wäre es mit einer App, die Lieblingsballaden auf Knopfdruck in einen Bass-lastigen EDM-Track für spontane Tanzeinlagen verwandeln kann? HARMAN International, eine hundertprozentige Tochtergesellschaft von Samsung Electronics Co. Ltd., die sich auf vernetzte Technologien für Automobil-, Konsum- und Unternehmensmärkte konzentriert, hat zu diesen Fragen sowie zu aktuellen Hörgewohnheiten und der Zukunft des Hörens eine neue Verbraucherstudie1 veröffentlicht.

LIGO has explained how it processes gravitational wave data in greater detail than ever before. But some physicists still say the analysis contains mistakes

May 25 - A bed sensor developed by an Israeli team is proving to be an effective and more reliable alternative to conventional patient monitoring technology. The sensor is designed to unobtrusively monitor a patient's vital signs from beneath their mattress and is less prone to sending out false alarms to nursing staff. Tara Cleary reports.

The coronavirus has helped make Big Tech too big to fail. Before the pandemic, political pressure in D.C. and Brussels was mounting on Silicon Valley giants like Facebook. Gina Chon explains how their size has been an asset in a crisis, which will mute arguments to break them up.

Could President Trump refuse to pay back the $1.1 trln the U.S. owes to China? While markets would hate the idea, it’s theoretically possible thanks to broad powers designed for times of emergency. John Foley explains how this dangerous weapon could be used if push came to shove.

South Africa's central bank has temporarily prohibited the use of debt issued by the Land Bank as collateral after the state agricultural lender was downgraded deeper into junk status and missed $2.7 billion in loan repayments.

Title: Study Casts Doubt on Use of Common Antibiotic for UTIs in Women
Category: Health News
Created: 4/30/2015 12:00:00 AM
Last Editorial Review: 5/1/2015 12:00:00 AM

Title: Experts Cast Doubt on Notion That New Strain of Coronavirus Is More Infectious
Category: Health News
Created: 5/7/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM

This first-in-human phase I study evaluated the pharmacokinetics, safety, and preliminary efficacy of telisotuzumab, formerly called ABT-700, an antagonistic antibody directed against c-Met. For dose escalation (3+3 design), 3 to 6 patients with advanced solid tumors were enrolled into four dose cohorts (5–25 mg/kg). In the dose-expansion phase, a subset of patients was prospectively selected for MET amplification (FISH screening). Patients received telisotuzumab intravenously on day 1 every 21 days. For dose expansion, 15 mg/kg was chosen as the dose on the basis of safety, pharmacokinetics, and other data from the escalation cohorts. Forty-five patients were enrolled and received at least one dose of telisotuzumab (dose escalation, n = 15; dose expansion, n = 30). Telisotuzumab showed a linear pharmacokinetics profile; peak plasma concentration was proportional to dose level. There were no acute infusion reactions and no dose-limiting toxicities were observed. The most common treatment-related adverse events included hypoalbuminemia (n = 9, 20.0%) and fatigue (n = 5, 11.1%). By Response Evaluation Criteria In Solid Tumors (RECIST), 4 of 10 (40.0%) patients with MET-amplified tumors had confirmed partial response in target lesions (one ovarian, two gastric, and one esophageal), two (20.0%) had stable disease, three (30.0%) had progressive disease; one patient was unable to be evaluated. Among patients with nonamplified tumors (n = 35), no objective responses were observed; however, 11 patients had stable disease per RECIST criteria. In conclusion, telisotuzumab has an acceptable safety profile with clinical activity observed in patients with MET-amplified advanced solid tumors.

ABSTRACT

Anti-galactose-α-1,3-galactose (anti-α-Gal) antibody is naturally expressed at a high level in humans. It constitutes about 1% of immunoglobulins found in human blood. Here, we designed a live attenuated influenza virus vaccine that can generate α-Gal epitopes in infected cells in order to facilitate opsonization of infected cells, thereby enhancing vaccine-induced immune responses. In the presence of normal human sera, cells infected with this mutant can enhance phagocytosis of human macrophages and cytotoxicity of NK cells in vitro. Using a knockout mouse strain that allows expression of anti-α-Gal antibody in vivo, we showed that this strategy can increase vaccine immunogenicity and the breadth of protection. This vaccine can induce 100% protection against a lethal heterosubtypic group 1 (H5) or group 2 (mouse-adapted H3) influenza virus challenge in the mouse model. In contrast, its heterosubtypic protective effect in wild-type or knockout mice that do not have anti-α-Gal antibody expression is only partial, demonstrating that the enhanced vaccine-induced protection requires anti-α-Gal antibody upon vaccination. Anti-α-Gal-expressing knockout mice immunized with this vaccine produce robust humoral and cell-mediated responses upon a lethal virus challenge. This vaccine can stimulate CD11b^lo/– pulmonary dendritic cells, which are known to be crucial for clearance of influenza virus. Our approach provides a novel strategy for developing next-generation influenza virus vaccines.

IMPORTANCE Influenza A viruses have multiple HA subtypes that are antigenically diverse. Classical influenza virus vaccines are subtype specific, and they cannot induce satisfactory heterosubtypic immunity against multiple influenza virus subtypes. Here, we developed a live attenuated H1N1 influenza virus vaccine that allows the expression of α-Gal epitopes by infected cells. Anti-α-Gal antibody is naturally produced by humans. In the presence of this antibody, human cells infected with this experimental vaccine virus can enhance several antibody-mediated immune responses in vitro. Importantly, mice expressing anti-α-Gal antibody in vivo can be fully protected by this H1N1 vaccine against a lethal H5 or H3 virus challenge. Our work demonstrates a new strategy for using a single influenza virus strain to induce broadly cross-reactive immune responses against different influenza virus subtypes.