COVID-19 has propelled the market for antimicrobials of all types over the past year, this n-tech study takes a look at business potential for smart materials with antimicrobial functionality in a post vaccine world.

Akhane Thiphavong Offers Insight into mRNA/LNP-Based and Adenoviral COVID-19 Vaccines

Alfa Cytology has unveiled new services on oncolytic viral therapy for pancreatic cancer research.

CMV is known to be present in semen of HIV-infected men, factors leading to shedding of each virus are unknown. Studies determining the efficacy of adding anti-CMV treatment strategies to HAART on lowering the semen burden of CMV are urgently needed

Considering the major societal disruptions brought on by government mandates responding to the COVID19 pandemic, all communities owe their residents an objective review of the mandates imposed.

The Message: Don't Keep it to Yourself – Share It

Branch & Dean - "Us Back in USA" and the official music video on all platforms now!

So you want to make an awesome infographic, but you aren’t sure where to start. Capsicum Mediaworks has 27 (Secrets) on How To Create An Awesome Viral Infographic in 2023.

This is definitely and example of “Do what I say, not what I do”.

There’s some fantastic information here! Ironically, this is NOT a great infographic. Saving a bunch of text as a JPG file does not make a good infographic. This infographic design goes against some of their own best advice! More visuals, less text. Make it big, not gigantic. Highlight/focus on the important points.

We all know that beautiful infographics are much more interesting as compared to long, plain text. It is the basic human tendency to associate more with anything that explains the same point with more visual appeal and less jargon.

Which is why infographics have become such a big deal.

The pictorial representation of the data, colorful backgrounds, short, to-the-point text, and easy to understand themes, are just some of the reasons why infographics have surpassed other digital marketing strategies in terms of popularity. And they are definitely here to stay.

So if you haven't jumped on this bandwagon yet, it's high time you do!

Found on Capsicum Mediaworks.

Viruses are invading pathogens that infect host cells and rapidly replicate throughout the body. They carry a small piece of genetic material such as DNA o

Viruses are invading pathogens that infect host cells and rapidly replicate throughout the body. They carry a small piece of genetic material such as DNA o

Last year I had this crazy idea -

Creating Viral Videos (A Classroom Project)

Taking to his Twitter account, the 'Walk Em Down' rapper plays down the fact that he got punched by the said fan even though all of his crew helped him during the physical altercation at the beach.

Clearly having no hard feeling over the incident, the 'Grown Ups' actor jokes that he left the restaurant simply because 'the all-you-can-eat deal didn't apply to the milkshakes.'

Setting the record straight on the image of her wearing the infamous tank top, the 'This Is Paris' star reveals that the statement seemingly emblazoned on her white top was 'completely photoshopped.'

Diego Santos habla sobre el papel de las redes frente al Coronavirus

Constipated scorpions, nature and nurture and why we try to cool fevers.

[Written by Don Burgess] If you ask any non-resident what they know about Bermuda, they will normally say either the Triangle or our shorts. Practically every Olympic Opening Ceremony recognizes our island for wearing Bermuda shorts, but for Paris, the focus was on the Triangle. Buzzfeed News, in an article entitled ‘The 38 funniest jokes about […]

1. Melania Trump's 'I am the most bullied person' video viral as she 'rejects' Jill Biden's tea invite  The Times of India
2. Melania Trump declines invite to meet Jill Biden over Mar-a-Lago raids when FBI ’snooped through her wardrobe’  Mint
3. Jimmy Kimmel again mocks Donald Trump for Melania's ‘interesting’ decision to…  Hindustan Times
4. Biden Invites Trump To White House, But Why Is Melania Refusing To Go?  News18
5. Melania Trump To Skip White House Meeting With Jill Biden: Report  NDTV

Everyone needs to read this woman's insightful Facebook post amidst the whole college admission's scandal dominating our news feeds. 

I’m definitely going to do this again! READ MORE...

Systematic review produced by the EPPI-Centre in 2015.This systematic review aimed to evaluate the effect of HAART and ARV monotherapy on liver disease progression and liver-related mortality in individuals co-infected with HIV and hepatitis C, including in patients with haemophilia.

IKEA hacks that go viral? It’s often the simplest ideas, brilliantly executed, mixed with a healthy dose of “It’s so easy, even you can do it” appeal. The latest sensation comes from Ayse Balci of @interiorundco, whose stylish DIY project has been turning heads on Instagram, amassing an impressive 115,000 likes and counting. Have you seen it yet? It’s a fantastic DIY project that transforms the popular and affordable 13 3/4″ LACK side table into a stylish chrome cube side […]

The post How a Basic IKEA Table Became a Viral Sensation (So Easy Anyone Can DIY It) appeared first on IKEA Hackers.

1. Song Jae Rim Passes Away: South Korean Star's Last Post Goes Viral, His Cryptic Insta Bio Grabs Eyeballs  News18
2. Song Jae Rim death: South Korean actor's last Instagram post sparks concern among fans  The Economic Times
3. South Korea’s popular actor Song Jae Rim found dead in Seoul apartment  Mint
4. Song Jae Rim's recent Instagram bio update was about 'starting a long journey'  Moneycontrol
5. 'My Military Valentine' fame South Korean actor Song Jae-rim dies 39  India TV News

KwaZulu-Natal police commissioner Lieutenant General Nhlanhla Mkhwanazi has ordered an "immediate investigation" after a video went viral on social media of a police officer slapping and pulling around a man.

There appeared to be a definite frost between first lady Jill Biden and Vice President Kamala Harris during a Veterans Day event at Arlington National Cemetery on Monday. A close-up […]

The post Footage of Jill Biden and Kamala Harris Sitting Side-by-Side at Veterans Day Event Goes Viral appeared first on The Western Journal.

HIV Type 1 (HIV-1) and simian immunodeficiency virus (SIV) display differential replication kinetics in macrophages. This is because high expression levels of the active host deoxynucleotide triphosphohydrolase sterile α motif domain and histidine-aspartate domain–containing protein 1 (SAMHD1) deplete intracellular dNTPs, which restrict HIV-1 reverse transcription, and result in a restrictive infection in this myeloid cell type. Some SIVs overcome SAMHD1 restriction using viral protein X (Vpx), a viral accessory protein that induces proteasomal degradation of SAMHD1, increasing cellular dNTP concentrations and enabling efficient proviral DNA synthesis. We previously reported that SAMHD1-noncounteracting lentiviruses may have evolved to harbor RT proteins that efficiently polymerize DNA, even at low dNTP concentrations, to circumvent SAMHD1 restriction. Here we investigated whether RTs from SIVmac239 virus lacking a Vpx protein evolve during in vivo infection to more efficiently synthesize DNA at the low dNTP concentrations found in macrophages. Sequence analysis of RTs cloned from Vpx (+) and Vpx (−) SIVmac239–infected animals revealed that Vpx (−) RTs contained more extensive mutations than Vpx (+) RTs. Although the amino acid substitutions were dispersed indiscriminately across the protein, steady-state and pre-steady-state analysis demonstrated that selected SIVmac239 Vpx (−) RTs are characterized by higher catalytic efficiency and incorporation efficiency values than RTs cloned from SIVmac239 Vpx (+) infections. Overall, this study supports the possibility that the loss of Vpx may generate in vivo SIVmac239 RT variants that can counteract the limited availability of dNTP substrate in macrophages.

Viral infection is one environmental factor that may contribute to the initiation of pancreatic β-cell destruction during the development of autoimmune diabetes. Picornaviruses, such as encephalomyocarditis virus (EMCV), induce a pro-inflammatory response in islets leading to local production of cytokines, such as IL-1, by resident islet leukocytes. Furthermore, IL-1 is known to stimulate β-cell expression of iNOS and production of the free radical nitric oxide. The purpose of this study was to determine whether nitric oxide contributes to the β-cell response to viral infection. We show that nitric oxide protects β-cells against virally mediated lysis by limiting EMCV replication. This protection requires low micromolar, or iNOS-derived, levels of nitric oxide. At these concentrations nitric oxide inhibits the Krebs enzyme aconitase and complex IV of the electron transport chain. Like nitric oxide, pharmacological inhibition of mitochondrial oxidative metabolism attenuates EMCV-mediated β-cell lysis by inhibiting viral replication. These findings provide novel evidence that cytokine signaling in β-cells functions to limit viral replication and subsequent β-cell lysis by attenuating mitochondrial oxidative metabolism in a nitric oxide–dependent manner.

Type I and III interferons induce expression of the “myxovirus resistance proteins” MxA in human cells and its ortholog Mx1 in murine cells. Human MxA forms cytoplasmic structures, whereas murine Mx1 forms nuclear bodies. Whereas both HuMxA and MuMx1 are antiviral toward influenza A virus (FLUAV) (an orthomyxovirus), only HuMxA is considered antiviral toward vesicular stomatitis virus (VSV) (a rhabdovirus). We previously reported that the cytoplasmic human GFP-MxA structures were phase-separated membraneless organelles (“biomolecular condensates”). In the present study, we investigated whether nuclear murine Mx1 structures might also represent phase-separated biomolecular condensates. The transient expression of murine GFP-Mx1 in human Huh7 hepatoma, human Mich-2H6 melanoma, and murine NIH 3T3 cells led to the appearance of Mx1 nuclear bodies. These GFP-MuMx1 nuclear bodies were rapidly disassembled by exposing cells to 1,6-hexanediol (5%, w/v), or to hypotonic buffer (40–50 mosm), consistent with properties of membraneless phase-separated condensates. Fluorescence recovery after photobleaching (FRAP) assays revealed that the GFP-MuMx1 nuclear bodies upon photobleaching showed a slow partial recovery (mobile fraction: ∼18%) suggestive of a gel-like consistency. Surprisingly, expression of GFP-MuMx1 in Huh7 cells also led to the appearance of GFP-MuMx1 in 20–30% of transfected cells in a novel cytoplasmic giantin-based intermediate filament meshwork and in cytoplasmic bodies. Remarkably, Huh7 cells with cytoplasmic murine GFP-MuMx1 filaments, but not those with only nuclear bodies, showed antiviral activity toward VSV. Thus, GFP-MuMx1 nuclear bodies comprised phase-separated condensates. Unexpectedly, GFP-MuMx1 in Huh7 cells also associated with cytoplasmic giantin-based intermediate filaments, and such cells showed antiviral activity toward VSV.

A Kentucky teen who became the subject of a viral video after a class field trip warned viewers of the Republican National Convention of an "outrage mob" that threatens to silence conservative viewpoints.

The baby pygmy hippopotamus in a Thailand zoo has taken the internet by storm, and keepers hope she will help gain momentum for conservation efforts

Paramotorists spotted the dog while soaring above one of Giza's pyramids last week

Viral country singer-songwriter and former reality-star contestant Sam Barber will bring his “Restless Mind” tour to Happy Valley at 7:30 p.m. Thursday, Nov. 7, in Eisenhower Auditorium.

Some might say these feeding numbers are slightly skewed.

What's Viral

Shilpa Shetty’s son Viaan was excited to meet the social media powerhouses

The first movie released in 2018 and featured Janhvi Kapoor and Ishaan Khatter in the lead roles

Priyanka will next be seen in Heads Of State

Soan Papdi Viral Video: Just after Diwali, an unexpected video of the making process of Soan Papdi surfaced online

A video showing a person trying bizarre savoury ice cream flavours, including biryani, ketchup, chips, etc, has received a lot of interest on Instagram.

The video begins with the chef pouring a big spoonful of cheese sauce onto a sizzling teppan griddle. Take a look:

The viral video of ice cube pakoras has received 6.2 million views.

A light-hearted video showing leftover Diwali faral (Maharashtrian snacks) being eaten with tea has got foodies talking on Instagram.

"My biggest honour in my journey as Food Pharmer is when Sudha Murthy Ma'am contacted me," content creator Revant Himatsingka said.