Washington — The Department of Transportation is requesting public comment on a proposed rule that would allow the use of electronic forms and signatures for drug and alcohol testing.

The joint effort provides Heathrow with a unified view across large-scale airport operations to secure people and assets.

These fall arrest platforms keep operators safe and mobile when work requires them to exit a mobile elevating work platform.

Washington — The Truck Safety Coalition is calling on the Department of Transportation and Congress to advance “critical truck safety reforms” after the recent release of its “Deadliest Truck Crash States” report.

Washington — The Department of Transportation is accepting comment on a proposed rule that would allow the use of electronic forms and signatures for drug and alcohol testing.

Solely says it used its signature, patented cold-pressing process to transform dried green bananas into a traditional fusilli shape and texture. The dark-colored Organic Green Banana Fusilli Pasta cooks to an al-dente texture in just four minutes and is ready to be topped with a sauce or other ingredients.

The Good Plastic Company is turning trash into treasure, giving old plastic a glamorous makeover.

New remote service tools and robust asset management platforms enable food and beverage companies to envision AI-based strategies and facilitate product innovation across the enterprise.

Children's Geographies; 12/01/2022
(AN 160715512); ISSN: 14733285
Academic Search Premier

About the role

We are looking for enthusiastic Graduate Electronics or Embedded System Engineer to join Arm’s Hardware Platform team, who are working at the forefront of embedded design based around Arm IP products. We are responsible for

• Designing and releasing the latest Arm IP technologies in FPGA image, enabling pre-silicon software and ecosystem development, reducing time to market.
• Creating physical hardware development platforms, based around Arm’s custom system-on-chip (SoC) and FPGAs for software development and validation activities for both our external partners/customers and our internal development teams.

If you’re interested in:

• The potential to work on all aspects of product development, from specification to customer release.
• Eager to learn, a willingness to work across disciplines.
• The challenges of bringing up a new development board.
•  

Creating and validating Verilog RTL design in FPGA.

• Gaining a deeper understanding of system architecture and performance.
• Working alongside many other teams including system architects, CPU / System IP designers, physical chip layout / packaging engineers.
• Interaction with Arm’s partners and customers both through the support organisation and directly.

Then we have a role for you!

What will I be accountable for?

As a Graduate, you will be placed in a development team at Arm’s offices in Cambridge, UK where you will have a mentor, and be able to get to grips with the problems ranging across many hardware and software areas.  You will be working across all aspects of the product lifecycle whilst being supported by and learning from the rest of the team.

About the role

We are looking for enthusiastic Graduate Electronics or Embedded System Engineer to join Arm’s Hardware Platform team, who are working at the forefront in the following embedded areas:

• Development and validation of physical hardware platforms, based around Arm’s custom system-on-chip (SoC) and FPGAs.
• Creating software to test Arm systems both in simulation and in hardware (FPGA & Silicon)
• Porting existing simulation/emulation RTL validation software to real hardware
• Create and maintain Build environments & Automation tooling to ensure we supply high quality products
• Software design and implementation of reference firmware for Arm processors and systems – for example working on the software to enable our cutting-edge CoreLink secure subsystems
• Software stack development to enable Arm IP. This includes implementing HALs, drivers, connectivity, security, power and control components
• Board support firmware using STM32 and LPC11 microcontrollers
• Operating system development (Linux, mbedOS, FreeRTOS, etc)
• Development of reference software and demos for Arm Partners to use and replicate in their own products.
• Support and maintenance

If you’re interested in:

• The potential to work on all aspects of product development, from specification to customer release.
• Eager to learn, willing to give anything a go.
• The challenges of bringing up a new development board.
• How to build, test and debug full software stacks on hardware that hasn’t yet been manufactured
• Gaining a deeper understanding of system architecture and performance
• Working alongside system hardware designers to develop the best platforms to support Arm’s partners

Then we have a role for you!

What will I be accountable for?

As a Graduate, you will be placed in a development team at Arm’s offices in Cambridge, UK where you will have a mentor, and be able to get to grips with the problems ranging across many software areas.  You will be working across all aspects of the software lifecycle whilst being supported by and learning from the rest of the team.  You will also be offered the opportunity to explore other teams within Arm during your first 12 months with us, as part of our Graduate Rotation programme.

Whilst a lot of our work does involve Open Source software, many tasks require working with development platforms, or simulated hardware environments where features are being developed and tested before the physical devices have been built, so the problems you will be expected to understand and solve are ones that are yet unknown to the general community.

Amy Pigliacampo revamps a Colorado home with a vibrant aesthetic, reusing key elements while infusing modern touches throughout the space.

Hibbing native Connie Evingson will be performing tonight at Crooners Lounge in Fridley. That's one of your many musical options this New Year's Eve.

Thursday afternoon she'll be playing in the intimate Clown Lounge under the Turf Club. Then Friday night she'll be at the Palace Theatre in downtown St. Paul.

The Wiser Way explained the overarching concept of cognitive distortion, an "all or nothing" way of thinking and how to break its cycle.

It's auction day for Alex Jones' Infowars. The Infowars studio and most other assets of the conspiracy theorist's company are expected to be sold off Wednesday. 

The structures of five ammonium salt forms of mono­sulfonated azo dyes, derivatives of 4-(2-phenyldiazen-1-yl)benzenesulfonate, with the general formula [NH4][O3S(C6H4)NN(C6H3)RR']·XH2O [R = OH, NH2 or N(C2H4OH)2; R' = H or OH] are presented. All form simple layered structures with alternating hydro­phobic (organic) and hydro­philic (cation, solvent and polar groups) layers. To assess for isostructural behaviour of the ammonium cation with M+ ions, the packing of these structures is compared with literature examples. To aid this comparison, the corresponding structures of four potassium salt forms of the mono­sulfonated azo dyes are also presented herein. Of the five ammonium salts it is found that three have isostructural equivalents. In two cases this equivalent is a potassium salt form and in one case it is a rubidium salt form. The isostructurality of ion packing and of unit-cell symmetry and dimensions tolerates cases where the ammonium ions form somewhat different inter­action types with coformer species than do the potassium or rubidium ions. No sodium salt forms are found to be isostructural with any ammonium equivalent. However, similarities in the anion packing within a single hydro­phobic layer are found for a group that consists of the ammonium and rubidium salt forms of one azo anion species and the sodium and silver salt forms of a different azo species.

Treating the amide acetanilide (N-phenyl­acetamide, C8H9NO) with aqueous strong acids allowed the structures of five hemi-protonated salt forms of acetanilide to be elucidated. N-(1-Hy­droxy­ethyl­idene)anilinium chloride–N-phenyl­acetamide (1/1), [(C8H9NO)2H][Cl], and the bromide, [(C8H9NO)2H][Br], triiodide, [(C8H9NO)2H][I3], tetra­fluoro­borate, [(C8H9NO)2H][BF4], and di­iodo­bromide hemi(diiodine), [(C8H9NO)2H][I2Br]·0.5I2, analogues all feature centrosymmetric dimeric units linked by O—H⋯O hy­dro­gen bonds that extend into one-dimensional hy­dro­gen-bonded chains through N—H⋯X inter­actions, where X is the halide atom of the anion. Protonation occurs at the amide O atom and results in systematic lengthening of the C=O bond and a corresponding shortening of the C—N bond. The size of these geometric changes is similar to those found for hemi-protonated paracetamol structures, but less than those in fully protonated paracetamol structures. The bond angles of the amide fragments are also found to change on protonation, but these angular changes are also influenced by conformation, namely, whether the amide group is coplanar with the phenyl ring or twisted out of plane.

A key prerequisite for the successful application of protein crystallography in drug discovery is to establish a robust crystallization system for a new drug-target protein fast enough to deliver crystal structures when the first inhibitors have been identified in the hit-finding campaign or, at the latest, in the subsequent hit-to-lead process. The first crucial step towards generating well folded proteins with a high likelihood of crystallizing is the identification of suitable truncation variants of the target protein. In some cases an optimal length variant alone is not sufficient to support crystallization and additional surface mutations need to be introduced to obtain suitable crystals. In this contribution, four case studies are presented in which rationally designed surface modifications were key to establishing crystallization conditions for the target proteins (the protein kinases Aurora-C, IRAK4 and BUB1, and the KRAS–SOS1 complex). The design process which led to well diffracting crystals is described and the crystal packing is analysed to understand retrospectively how the specific surface mutations promoted successful crystallization. The presented design approaches are routinely used in our team to support the establishment of robust crystallization systems which enable structure-guided inhibitor optimization for hit-to-lead and lead-optimization projects in pharmaceutical research.

The title compound, C12H16N2O, is a hy­droxy-substituted mono­amine alkaloid, and the primary metabolite of the naturally occurring psychedelic compound psilocybin. Crystalline forms of psilocin are known, but their characterization by single-crystal structure analysis is limited. Herein, two anhydrous polymorphic forms (I and II) of psilocin are described. The crystal structure of polymorphic Form I, in space group P21/c, was first reported in 1974. Along with the redeterm­ination to modern standards and unambiguous location of the acidic H atom and variable-temperature single-crystal unit-cell determinations for Form I, the Form II polymorph of the title compound, which crystallizes in the monoclinic space group P21/n, is described for the first time. The psilocin mol­ecules are present in both forms in their phenol–amine tautomeric forms (not resolved in the 1974 report). The mol­ecules in Forms I and II, however, feature different conformations of their N,N-dimethyl ethyl­ene substituent, with the N—C—C—C link in Form I being trans and in Form II being gauche, allowing the latter to bend back to the hydroxyl group of the same mol­ecule, leading to the formation of a strong intra­molecular O—H⋯N hydrogen bond between the hydroxyl moiety and ethyl­amino-nitro­gen group. In the extended structure of Form II, the mol­ecules form one-dimensional strands through N—H⋯O hydrogen bonds from the indole group to the oxygen atom of the hydroxyl moiety of an adjacent mol­ecule. Form II exhibits whole-mol­ecule disorder due to a pseudo-mirror operation, with an occupancy ratio of 0.689 (5):0.311 (5) for the two components. In contrast, Form I does not feature intra­molecular hydrogen bonds but forms a layered structure through inter­molecular N—H⋯O and O—H⋯N hydrogen bonds.

An implementation of Slater-type spherical scattering factors for X-ray and electron diffraction for elements in the range Z = 1–103 is presented within the software Olex2. Both high- and low-angle Fourier behaviour of atomic electron density and electrostatic potential can thus be addressed, in contrast to the limited flexibility of the four Gaussian plus constant descriptions which are currently the most widely used method for calculating atomic scattering factors during refinement. The implementation presented here accommodates the increasing complexity of the electronic structure of heavier elements by using complete atomic wavefunctions without any interpolation between precalculated tables or intermediate fitting functions. Atomic wavefunctions for singly charged ions are implemented and made accessible, and these show drastic changes in electron diffraction scattering factors compared with the neutral atom. A comparison between the two different spherical models of neutral atoms is presented as an example for four different kinds of X-ray and two electron diffraction structures, and comparisons of refinement results using the existing diffraction data are discussed. A systematic but slight improvement in R values and residual densities can be observed when using the new scattering factors, and this is discussed relative to effects on the atomic displacement parameters and atomic positions, which are prominent near the heavier elements in a structure.

The 1st edition of the Fintech for Marketplaces and Platforms Report covers essential ecommerce trends and future perspectives.

Widespread reforms are needed to ensure that all children are equipped with the skills and instruction they need to learn to read, according to a new report from a committee of the National Research Council.

Legal responses to juvenile offending should be grounded in scientific knowledge about adolescent development and tailored to an individual offenders needs and social environment, says a new report from the National Research Council.

The best indicator of whether a disabled adult who receives Social Security benefits is capable of managing his or her benefits is evidence of real-world performance of meeting his or her own basic needs, rather than an office-based assessment of financial competence, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine calls for a series of substantial reforms to strengthen the U.S. biomedical research system for the next generation of scientists.

On November 15, 2020, after 4 months in large-scale Phase 3 clinical testing, Moderna received resounding proof that its new class of medicines based on messenger RNA encased in lipid nanoparticles could be safely deployed as a highly effective vaccine to combat the COVID-19 pandemic.

Geothermal power is a renewable energy source that uses the Earth's internal heat to produce electricity and heat water. One-hundred and fifty megawatts is roughly enough electricity to power 38,000 homes.

Companies such as Meta have said such a move would not solve the telcos' financial problems and ignores hefty investments by tech companies.

For users in India between 13 and 18 years of age, apps may now have to get parental consent by verifying the identity of the children and their parents.. The Digital Personal Data Protection bill defines children as those below 18 years, which is above the global threshold. Users above 13 years of age, for example, are typically allowed on many social media platforms.

It offers centralized request management, omnichannel integration, self-service capabilities, enhanced visibility for business partners, employee training and tools, powerful analytics capabilities, seamless integration with existing systems, and comprehensive service offerings.

The luxurious Wythe Hotel in Brooklyn, New York, was once a waterfront barrel and rope factory. This renovated structure now has 72 boutique guest rooms. As part of the update, it was important to retain the character of the original turn of the century building, which opened in 1901. In order to convert the cold, utilitarian factory space into comfortable rooms, a major mechanical update was required. By adding radiant floor heat, they were able to meet and exceed the comfort benchmark of a modern-day hotel while balancing for energy efficiency.

Experts note how the direct-to-consumer channel is impacting beverage categories and sales.

Alsco Uniforms to be part of the solution to growing Women's sports

Dr. Aaron Galbraith is providing new patient forms online for more efficient appointment times.

Dr. Stephen Rogers, Fall River podiatrist, improves first time visits with new patient forms.

Dr. Douglas Goff, Columbus dentist, spends more one-on-one time with his patients due to the availability of online patient forms.

Dr. Michael Laureola offers helpful dental health care tips for optimal oral health.

Hyro's AI seamlessly integrates with Cisco's telephony and agent desktop infrastructure to create an intelligent, conversational call-routing system

Region's Premier FBO to Exhibit at 2024 NBAA Schedulers & Dispatchers Conference

London firm Source Marketing Direct, MD, Hector Montalvo leads debate over concerns that traditional forms of marketing are failing signalling more effective marketing strategies must be implemented by brands wishing to survive 2013

Equipped with advanced technology, new facility minimizes environmental impact and supports sustainable growth.

Alsco Uniforms is the Official Sponsor of the "Mop Crew"

Showcasing "It Pays to Keep Clean" with Alsco Uniforms

Alsco Uniforms Branding to Appear on Mops and the Mop Crew at Magic Home Games

Partnership showcases why It Pays to Keep Clean with Alsco Uniforms

Partnership reflects a mutual ambition to uphold a high standard of service, cleanliness and community engagement

Contribution Aids in the Restoration and Rebuilding Efforts in the Aftermath of the Maui Wildfires

Kings' court to showcase why It Pays to Keep CleanTM with Alsco Uniforms

Elf insiders report that the Mop Crew is thrilled about their newfound sponsorship