Donald Trump won the election. The House and Senate are in Republican hands. That means the GOP now owns the debt and its consequences. This responsibility, while too much for past politicians, presents the opportunity of a lifetime: namely, to be the ones who put the government back on fiscal…

Os contornos e prioridades da nova Presidência de Donald Trump estão começando a tomar forma à medida que ele faz as indicações a cargos importantes.

The FBI conducted a raid at Polymarket CEO Shayne Coplan's home Wednesday morning, a company spokesperson told BI.

A CNN anchor sounded surprised by the level of interest President Joe Biden’s staff members showed regarding President-elect Donald Trump’s arrival at the White House Wednesday. As “Newsroom” host Pamela […]

The post CNN Anchor Calls White House Staffers' Response to Trump Visit 'Really Stunning' appeared first on The Western Journal.

Handre Pollard and Manie Libbok are obviously two very different players, but attack coach Tony Brown views them as the same when it comes to driving the Springbok attack.

14 games into the season, Detroit's PK is a disaster. Here's more on the problem and potential solutions

The Association of Yukon Fire Chiefs says the government of Yukon needs to invest more money in the Yukon Fire Marshal's Office so it can continue to adequately support the territory's fire services.

A new report claims that despite overall sales declining, Apple's iPad continues to sell steadily, and is second only to the iPhone.

Snapdragon 8 Elite chipset was launched by Qualcomm at its Snapdragon Summit in Hawaii last month as a successor to the Snapdragon 8 Gen 3. The rumour mill now suggests that its successor, the purported Snapdragon 8 Elite 2 SoC, might offer an even bigger jump in single and multi-core performance, despite recent changes suggested in its development plans.

The father of a 10-year-old British-Pakistani girl on Wednesday admitted that he killed his daughter but maintained he had not meant to harm her, even as he beat her when she lay dying.

ZHUHAI, China — Authorities in the southern Chinese city of Zhuhai removed wreaths, candles and even bottles of Chinese alcohol laid at the scene of the deadliest mass killing in the country in a decade, as the government scrambled to respond and censor the outrage online. On Monday, a male driver angry at his divorce settlement rammed his car into a crowd at a sports center in the city of 2.5 million, killing 35 people and injuring 43, but the government took almost a day to announce the death toll. This prompted an outrage on Chinese social media, where posts complaining about the government's slow response and raising questions about the mental health of a nation shaken by a recent spate of similar killings, were being quickly removed. Despite the efforts to clear the site in Zhuhai, which is near Macau, delivery drivers on motorbikes kept dropping off fresh flowers on Wednesday morning, even as authorities erected temporary barriers around the makeshift vigil area and deployed security personnel. “The authorities hadn’t released any information - some colleagues mentioned it and I couldn’t believe it at first, but it was confirmed later,” said a 50-year-old man who identified himself as Zheng who brought flowers to the site. “It’s just a spontaneous feeling I had. Even though I don’t know them personally, I had family members who passed away in the past, so I understand that feeling," said Zheng. Some wreaths carried handwritten notes: "Strangers travel well. May there be no demons in heaven,” read one. On another: “May there be no thugs in heaven. Good will triumph over evil. Rest in peace.” After initially allowing journalists to briefly speak to the people laying the flowers, a handful of security personnel sporting light blue uniforms and caps told reporters not to talk to the people or to film specific messages on the bouquets. The attack happened as Zhuhai captured China's attention with the People's Liberation Army's largest annual airshow, where a new stealth jet fighter is on display for the first time. China’s state broadcaster CCTV did not mention the attack in its 30-minute midday news bulletin. Instead, the program led with President Xi Jinping's departure for the APEC summit in Peru and devoted a portion of the airtime to the airshow. Other state media, such as China Daily's Chinese language website, also prominently displayed the news of Xi's upcoming visit to Peru. The current affairs part of China Daily's website and the local area page did not mention the incident either. Hundreds of rescue personnel were deployed to provide emergency treatment, and more than 300 healthcare workers from five hospitals worked around the clock to save lives, state media's Beijing Daily reported on Tuesday. There was no indication that the attack was related to the airshow. But it was the second such incident to occur during the Zhuhai airshow: in 2008, at least four people were killed and 20 injured when a man drove a truck into a crowded schoolyard during the airshow. Police said that attacker had been seeking revenge over a traffic dispute. Xi, cited by CCTV on Tuesday, ordered all-out efforts to treat the injured and demanded severe punishment for the perpetrator. The central government has dispatched a team to provide guidance on handling of the case, CCTV said. Violent crime is rare in China due to tight security and strict gun laws. However, a rise in reports of knife attacks in large cities has drawn public attention to safety in public spaces. The deadliest attack Reuters was able to identify in recent years in China took place in Urumqi, in China's western Xinjiang region, in 2014, in which suicide bombers killed 39 people and four of the five attackers also died.

[New Times] Prime Minister Edouard Ngirente has affirmed the government's commitment to advancing toward the nation's Vision 2050 goals, emphasizing resilience in the face of challenges.

Super Bowl champion Heath Evans offered advice to ESPN NFL analyst Ryan Clark after the former player said he would not and does not respect President-elect Trump.

ESPN NBA writer Brian Windhorst criticized the Los Angeles Lakers' plan for Bronny James, who won't be heading on the road with the G League South Bay Lakers.

Federal government departments are still allowed to advertise on TikTok despite mounting security concerns about the social media app, CBC News has learned. 

Commerzbank analizează opțiunea de a achiziționa o bancă germană de dimensiuni medii ca parte a strategiei de a evita o posibilă preluare de către UniCredit, potrivit Reuters. Planurile sunt într-o etapă incipientă, iar posibilele ținte ar putea include Hamburg Commercial Bank sau Oldenburgische Landesbank. Potrivit surselor Reuters, Commerzbank încearcă să conceapă un plan de apărare, ...

The post Commerzbank ia în considerare achiziționarea unui rival german pentru a respinge UniCredit appeared first on Forbes Romania.

Known for his humility, Ratan Tata leaves behind a legacy of compassion and generosity

Since striking out on my own, much of my time’s been dedicated to, well, the book. But I’ve also been fortunate enough to collaborate a bit with Filament Group on one of their projects: namely, a large-scale engagement that requires a responsive approach.

Needless to say, I am having the time of my life.

We’re also learning a lot, too. A lot of discussions about approach and execution have come up, largely because processes for a lot of this stuff don’t exist yet. That will, with a bit of hard work and community discussion, change over time. Still, there has been a lot of brilliant stuff created so far.

Here’s just one example:

The goal of this technique is to deliver optimized, contextual image sizes for responsive layouts that utilize dramatically different image sizes at different resolutions. Ideally, this approach will allow developers to start with mobile-optimized images in their HTML and specify a larger size to be used for users with larger screen resolutions — without requesting both image sizes, and without UA sniffing.

Check out the script, download it, and kick the tires a bit—feedback and tweaks are most welcome.

I realize that there are always going to be philosophical differences around responsive web design. But for me, the solutions-driven discussions are always going to be infinitely more interesting to me than the alternative.

Parthiv Patel will perform the dual role in the support staff led by head coach Ashish Nehra

Dr. Roccas is the author of Time and Despondency and talks about the meaning of despondency and how it is impacting the Church.

A conference on consequence management in response to acts of terrorism gathered today over sixty participants from the security and judiciary sectors as well as local communities.

Austrian Post has published its Q1-3 results revealing revenue of the Group rose by 13.6%.

An architectural project in Sutton aims to tackle the housing crisis while promoting sustainable development and social inclusion.

1. Usman Khawaja debunks strike rate 'myth' in McSweeney selection  ESPNcricinfo
2. ‘Don’t know where it started’: Uzzie hits out at ‘myth’ in defence of newcomer  Fox Sports
3. The phone call that surprised new skipper Inglis  cricket.com.au
4. ‘It’s a little more than a guess’: Bailey defends McSweeney selection as concerning stats revealed  Sydney Morning Herald
5. Khawaja backs McSweeney to star  Brisbane Times

1. Mam breaks silence: Bronco’s emotional response to police charge  Courier Mail
2. Brisbane Broncos star Ezra Mam charged over head-on collision, allegedly failing second drug test  ABC News
3. Ezra Mam issued court notice after allegedly failing secondary drug test  Fox Sports
4. Broncos’ Ezra Mam charged over drug test result after Uber crash  Brisbane Times
5. Broncos star charged after car crash  news.com.au

1. 'Wage dynamics not consistent with cutting the cash rate', despite slowdown in pay rises  ABC News
2. Real wages are growing at highest rate since 2020. But it’s unlikely to last  Sydney Morning Herald
3. Jobs market keeps grinding away as data update looms  The Canberra Times

Blue Jays general manager Ross Atkins declined to get into a back-and-forth with Marcus Stroman on Sunday afternoon, sidestepping criticism of the organization from his right-handed starter.

The activation of autonomic and hypothalamo-pituitary-adrenal (HPA) systems occurs interdependently with behavioral adjustments under varying environmental demands. Nevertheless, laboratory rodent studies examining the neural bases of stress responses have generally attributed increments in these systems to be monolithic, regardless of whether an active or passive coping strategy is employed. Using the shock probe defensive burying test (SPDB) to measure stress-coping features naturalistically in male and female rats, we identify a neural pathway whereby activity changes may promote distinctive response patterns of hemodynamic and HPA indices typifying active and passive coping phenotypes. Optogenetic excitation of the rostral medial prefrontal cortex (mPFC) input to the ventrolateral periaqueductal gray (vlPAG) decreased passive behavior (immobility), attenuated the glucocorticoid hormone response, but did not prevent arterial pressure and heart rate increases associated with rats’ active behavioral (defensive burying) engagement during the SPDB. In contrast, inhibition of the same pathway increased behavioral immobility and attenuated hemodynamic output but did not affect glucocorticoid increases. Further analyses confirmed that hemodynamic increments occurred preferentially during active behaviors and decrements during immobility epochs, whereas pathway manipulations, regardless of the directionality of effect, weakened these correlational relationships. Finally, neuroanatomical evidence indicated that the influence of the rostral mPFC->vlPAG pathway on coping response patterns is mediated predominantly through GABAergic neurons within vlPAG. These data highlight the importance of this prefrontal->midbrain connection in organizing stress-coping responses and in coordinating bodily systems with behavioral output for adaptation to aversive experiences.

Peripheral taste neurons exhibit functional, genetic, and morphological diversity, yet understanding how or if these attributes combine into taste neuron types remains unclear. In this study, we used male and female mice to relate taste bud innervation patterns to the function of a subset of proenkephalin-expressing (Penk+) taste neurons. We found that taste arbors (the portion of the axon within the taste bud) stemming from Penk+ neurons displayed diverse branching patterns and lacked stereotypical endings. The range in complexity observed for individual taste arbors from Penk+ neurons mirrored the entire population, suggesting that taste arbor morphologies are not primarily regulated by the neuron type. Notably, the distinguishing feature of arbors from Penk+ neurons was their propensity to come within 110 nm (in apposition with) different types of taste-transducing cells within the taste bud. This finding is contrary to the expectation of genetically defined taste neuron types that functionally represent a single stimulus. Consistently, further investigation of Penk+ neuron function revealed that they are more likely to respond to innately aversive stimuli—sour, bitter, and high salt concentrations—as compared with the full taste population. Penk+ neurons are less likely to respond to nonaversive stimuli—sucrose, umami, and low salt—compared with the full population. Our data support the presence of a genetically defined neuron type in the geniculate ganglion that is responsive to innately aversive stimuli. This implies that genetic expression might categorize peripheral taste neurons into hedonic groups, rather than simply identifying neurons that respond to a single stimulus.

No known believers from a Muslim background existed in Turkey when the first two OMers arrived in 1961. Now, nearly half of the 7,000 believers there can trace their journey through the Bible Correspondence Course.

Since 2007, the Bus4Life has visited 150 locations, welcomed 10,000 visitors and touched many lives, including one Romanian teen who comes back to God.

Since the Syrian war began, OM workers have served alongside locals, including Muslim background believers, to spread hope amongst desperate people.

An OM worker in Bosnia shares how the enduring faith of two elderly women of God has inspired her to also persevere to the end.

India vs South Africa 3rd T20I LIVE Updates: Varun Chakaravarthy has picked two wickets as South Africa are four down in their chase of 220 runs against India

1. Sri Lanka opt to bat; three ODI debutants for New Zealand  ESPNcricinfo
2. Mendis, Fernando tons deflate New Zealand  Cricbuzz
3. Sri Lanka beat New Zealand by 45-runs to go 1-0 up in ODI series  The Times of India
4. Sri Lanka wins toss, elects to bat in 1st ODI against New Zealand  Hindustan Times
5. NZ vs SL ODIs: New faces, spin pitches and Champions Trophy watch  ESPNcricinfo

“Climate change continues to happen, and it is important that Israel remains part of the efforts to mitigate the effects of climate change,” Behar said.

Without doubt, Turkiye gave the strongest response to Israel’s atrocities in Palestine through such steps as halting trade, President Recep Tayyip Erdogan said on Wednesday.

Ankara suspended all trade with Israel in May, citing a worsening humanitarian tragedy in Gaza, where Israel has killed more than 43,000 Palestinians since last October.

“As long as arms shipments continue, Israel will be more aggressive, as every day that Israel is not stopped, the situation in Palestine and Lebanon worsens,” Erdogan told reporters on his return flight from visits to Saudi Arabia and Azerbaijan.

One of the concrete steps that can be taken against Israel’s attacks is to work for recognition of the state of Palestine, he underscored, adding: “Without a two-state solution, peace and stability will not come to the region.”

“Trade restrictions and sanctions on Israel are another form of struggle. Active diplomacy to corner Israel in all areas and boost diplomatic pressure is also crucial. We’re in the middle of a great test of humanity,” the president said.

“Passing this test is only possible by being part of the humanitarian alliance. Otherwise, history will judge both those who stood by Israel and those who remained silent in the face of oppression.”

Erdogan also said Ankara’s initiative at the UN to prevent the shipment of weapons and ammunition to Israel has been supported by 52 countries and two international organizations.

“We recently sent a letter on this initiative to the president of the UN General Assembly, the president of the Security Council, and the UN secretary-general. At the (joint Arab-Muslim) summit in Riyadh, a decision was made to invite all organizations and Arab League members to sign our letter. Our country’s steps to halt the massacre and its humanitarian aid efforts were praised,” he added.

The Turkish president also highlighted that he had the opportunity to hold bilateral meetings during the summit, including with Saudi Crown Prince Mohammed bin Salman, adding that they had a fruitful meeting.

Emphasizing that he also held bilateral meetings in Baku, Azerbaijan, during the COP29 UN Climate Change Conference, Erdogan said that these meetings included discussions of bilateral ties and regional developments.

‘Climate is one of the most critical issues facing world’

On Turkiye’s zero emissions target for 2053, Erdogan said: “The climate issue is one of the most critical issues facing the world. Just as we care about wars, conflicts, and migration, we approach this issue with the same seriousness.”

“Turkiye is persistently discussing what measures we can take with the relevant ministries. We have taken, are taking, and will continue to take measures to use the world’s limited resources most efficiently and to elevate the civilization we have developed over centuries to a much higher level.

“Turkiye cares about this issue and is making every effort to do our part. However, finding a fundamental and lasting solution to this issue is not possible with the efforts of just us or a few countries together.”

He called for collective action to shoulder the burden of climate-related efforts.

“If some countries fully engage in the fight against climate change while others, driven by greed, ignore necessary measures or even increase pollution, we cannot overcome this problem,” warned Erdogan.

President Erdogan added that the importance of the Zero Waste initiative, spearheaded by Turkiye, is gaining more recognition every day and that efforts are being made to spread it and turn it into a way of life.

The initiative, which started in 2017 under First Lady Emine Erdogan’s leadership, aims to raise awareness of the importance of waste elimination in addressing climate change.

Hope ties with US move to different track under Trump

On the US’ incoming administration, Erdogan voiced hope that Donald Trump’s taking office in January will start to put ties between Ankara and Washington on a different track.

“Undoubtedly, there are always opportunities between the two countries. Our basic expectation is to assess these opportunities and take steps that will benefit both countries,” he said.

“The Trump administration views the economy as one of its main priorities. Turkiye, with its strategic geographical location and young population, is a country that offers investment opportunities.

“We can create new opportunities to boost the trade volume and encourage investments between the two countries. Particularly in energy, infrastructure, and technology, we can develop new collaborations,” he underlined.

Erdogan also expressed hope that President-elect Trump would take different steps for the region.

Asked about potential future meetings with US billionaire Elon Musk, one of Trump’s biggest supporters, Erdogan said: “The technological strides Turkiye is making are drawing attention worldwide. Technology is not an area where you can advance alone; you need collaboration. If cooperation opportunities arise in this field, steps can be taken with Musk.”

Possible normalization between Turkiye, Syria

Speaking of a possible reconciliation with Syria, Erdogan said Turkiye has reached out for normalization, expressing its belief that it would open the door to peace and stability in Syrian territories.

Cross-border operations are always in the cards for the country’s security, he said, expressing readiness to launch them anytime the country feels threatened.

Turkiye has launched several cross-border operations in recent years, in both northern Syria and northern Iraq, targeting terrorists who hide out there and destabilize the border or plot attacks on Turkish soil.

Reiterating Turkiye’s commitment to fighting terrorism while respecting Syria’s territorial integrity, Erdogan said that the presence of terrorist groups in northern Syria, notably the PKK, the PYD and the YPG, also poses a threat to its territorial integrity, adding that the Syrian government, well aware of this, must take steps to create a new climate in the country.

Erdogan also said the “threat of Israel,” right next to Syria, is no fairy tale, warning that the fire in the surrounding areas can quickly spread in the unstable lands.

In its 40-year terror campaign against Turkiye, the PKK — listed as a terrorist organization by Turkiye, the US, and the EU — has been responsible for the deaths of over 40,000 people, including women, children, and infants. The YPG is PKK’s Syrian offshoot.

In northern Syria, Ankara has launched a trio of successful anti-terror operations since 2016 to prevent the formation of a terror corridor and enable the peaceful settlement of residents: Euphrates Shield (2016), Olive Branch (2018), and Peace Spring (2019).

Advance care planning (ACP) is a complex and iterative communication process between patients, surrogates and clinicians that defines goals of care that may include, but is not limited to, documentation of advance directives. The aim of ACP is to promote patient-centred care tailored to the patient's clinical situation through informed preparation for the future and improved communication between patient, clinicians and surrogates, if the latter need to make decisions on patient's behalf.

The aim of this article is to review research related to ACP in acute and chronic respiratory failure, regarding the process, communication, shared decision-making, implementation and outcomes.

Research has produced controversial results on ACP interventions due to the heterogeneity of measures and outcomes, but positive outcomes have been described regarding the quality of patient–physician communication, preference for comfort care, decisional conflict and patient–caregiver congruence of preferences and improved documentation of ACP or advance directives.

The main barriers to ACP in chronic respiratory failure are the uncertainty of prognosis (particularly in the organ failure trajectory), the choice of the best timing for initiation and the lack of training of healthcare workers. In acute respiratory failure, the ACP process can be very short, should include the patient whenever possible, and is based on a discussion of treatments appropriate to the patient's functional status prior to the event (e.g. assessment of frailty) and clear communication of the likely consequences of possible options.

All healthcare worker dealing with patients with serious illnesses should have training in communication skills to promote engagement in ACP discussions.

Extracellular vesicles (EVs) released by various cells play crucial roles in intercellular communication within the respiratory system. This review explores the historical context and significance of research into extracellular vesicles. Categorised into exosomes (sized 30–150 nm), microvesicles (sized 50–1000 nm) and apoptotic bodies (sized 500–2000nm), based on their generation mechanisms, extracellular vesicles carry diverse cargoes of biomolecules, including proteins, lipids and nucleic acids. Respiratory ailments are the primary contributors to both mortality and morbidity across various populations globally, significantly impacting public health. Recent studies have underscored the pivotal role of extracellular vesicles, particularly their cargo content, in mediating intercellular communication between lung cells in respiratory diseases. This comprehensive review provides insights into extracellular vesicle mechanisms and emphasises their significance in major respiratory conditions, including acute lung injury, COPD, pulmonary hypertension, pulmonary fibrosis, asthma and lung cancer.

1. 'We've got a bit of history': Ricky Ponting responds to Gautam Gambhir's remarks, calls him 'prickly...  Moneycontrol
2. Ricky Ponting hits back at Gautam Gambhir, calls him 'prickly character'  The Times of India
3. 'That's a bad move, Ricky. What are you doing?': Ponting's Virat Kohli jibe questioned amid 'spicy' ball-tampering claim  Hindustan Times
4. "What Are You Doing?" Lee Warns Ricky Ricky Ponting Over 'Virat Kohli Remark'  NDTV Sports
5. ‘What Are You Doing?’: Former Australian Cricketer Hits Back At Ricky Ponting Over Remark On Virat Kohli’s Test Form  News24

Singer was one of the early favourites to win the talent show

A [fun] [way to say] [depression]