is Comment: Statistical Inference from a Predictive Perspective By projecteuclid.org Published On :: Wed, 08 Jan 2020 04:00 EST Alessandro Rinaldo, Ryan J. Tibshirani, Larry Wasserman. Source: Statistical Science, Volume 34, Number 4, 599--603.Abstract: What is the meaning of a regression parameter? Why is this the de facto standard object of interest for statistical inference? These are delicate issues, especially when the model is misspecified. We argue that focusing on predictive quantities may be a desirable alternative. Full Article
is Discussion of Models as Approximations I & II By projecteuclid.org Published On :: Wed, 08 Jan 2020 04:00 EST Dag Tjøstheim. Source: Statistical Science, Volume 34, Number 4, 575--579. Full Article
is Discussion of Models as Approximations I & II By projecteuclid.org Published On :: Wed, 08 Jan 2020 04:00 EST Sara van de Geer. Source: Statistical Science, Volume 34, Number 4, 566--568.Abstract: We discuss the papers “Models as Approximations” I & II, by A. Buja, R. Berk, L. Brown, E. George, E. Pitkin, M. Traskin, L. Zao and K. Zhang (Part I) and A. Buja, L. Brown, A. K. Kuchibhota, R. Berk, E. George and L. Zhao (Part II). We present a summary with some details for the generalized linear model. Full Article
is Conditionally Conjugate Mean-Field Variational Bayes for Logistic Models By projecteuclid.org Published On :: Fri, 11 Oct 2019 04:03 EDT Daniele Durante, Tommaso Rigon. Source: Statistical Science, Volume 34, Number 3, 472--485.Abstract: Variational Bayes (VB) is a common strategy for approximate Bayesian inference, but simple methods are only available for specific classes of models including, in particular, representations having conditionally conjugate constructions within an exponential family. Models with logit components are an apparently notable exception to this class, due to the absence of conjugacy among the logistic likelihood and the Gaussian priors for the coefficients in the linear predictor. To facilitate approximate inference within this widely used class of models, Jaakkola and Jordan ( Stat. Comput. 10 (2000) 25–37) proposed a simple variational approach which relies on a family of tangent quadratic lower bounds of the logistic log-likelihood, thus restoring conjugacy between these approximate bounds and the Gaussian priors. This strategy is still implemented successfully, but few attempts have been made to formally understand the reasons underlying its excellent performance. Following a review on VB for logistic models, we cover this gap by providing a formal connection between the above bound and a recent Pólya-gamma data augmentation for logistic regression. Such a result places the computational methods associated with the aforementioned bounds within the framework of variational inference for conditionally conjugate exponential family models, thereby allowing recent advances for this class to be inherited also by the methods relying on Jaakkola and Jordan ( Stat. Comput. 10 (2000) 25–37). Full Article
is User-Friendly Covariance Estimation for Heavy-Tailed Distributions By projecteuclid.org Published On :: Fri, 11 Oct 2019 04:03 EDT Yuan Ke, Stanislav Minsker, Zhao Ren, Qiang Sun, Wen-Xin Zhou. Source: Statistical Science, Volume 34, Number 3, 454--471.Abstract: We provide a survey of recent results on covariance estimation for heavy-tailed distributions. By unifying ideas scattered in the literature, we propose user-friendly methods that facilitate practical implementation. Specifically, we introduce elementwise and spectrumwise truncation operators, as well as their $M$-estimator counterparts, to robustify the sample covariance matrix. Different from the classical notion of robustness that is characterized by the breakdown property, we focus on the tail robustness which is evidenced by the connection between nonasymptotic deviation and confidence level. The key insight is that estimators should adapt to the sample size, dimensionality and noise level to achieve optimal tradeoff between bias and robustness. Furthermore, to facilitate practical implementation, we propose data-driven procedures that automatically calibrate the tuning parameters. We demonstrate their applications to a series of structured models in high dimensions, including the bandable and low-rank covariance matrices and sparse precision matrices. Numerical studies lend strong support to the proposed methods. Full Article
is The Importance of Being Clustered: Uncluttering the Trends of Statistics from 1970 to 2015 By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Laura Anderlucci, Angela Montanari, Cinzia Viroli. Source: Statistical Science, Volume 34, Number 2, 280--300.Abstract: In this paper, we retrace the recent history of statistics by analyzing all the papers published in five prestigious statistical journals since 1970, namely: The Annals of Statistics , Biometrika , Journal of the American Statistical Association , Journal of the Royal Statistical Society, Series B and Statistical Science . The aim is to construct a kind of “taxonomy” of the statistical papers by organizing and clustering them in main themes. In this sense being identified in a cluster means being important enough to be uncluttered in the vast and interconnected world of the statistical research. Since the main statistical research topics naturally born, evolve or die during time, we will also develop a dynamic clustering strategy, where a group in a time period is allowed to migrate or to merge into different groups in the following one. Results show that statistics is a very dynamic and evolving science, stimulated by the rise of new research questions and types of data. Full Article
is Statistical Analysis of Zero-Inflated Nonnegative Continuous Data: A Review By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Lei Liu, Ya-Chen Tina Shih, Robert L. Strawderman, Daowen Zhang, Bankole A. Johnson, Haitao Chai. Source: Statistical Science, Volume 34, Number 2, 253--279.Abstract: Zero-inflated nonnegative continuous (or semicontinuous) data arise frequently in biomedical, economical, and ecological studies. Examples include substance abuse, medical costs, medical care utilization, biomarkers (e.g., CD4 cell counts, coronary artery calcium scores), single cell gene expression rates, and (relative) abundance of microbiome. Such data are often characterized by the presence of a large portion of zero values and positive continuous values that are skewed to the right and heteroscedastic. Both of these features suggest that no simple parametric distribution may be suitable for modeling such type of outcomes. In this paper, we review statistical methods for analyzing zero-inflated nonnegative outcome data. We will start with the cross-sectional setting, discussing ways to separate zero and positive values and introducing flexible models to characterize right skewness and heteroscedasticity in the positive values. We will then present models of correlated zero-inflated nonnegative continuous data, using random effects to tackle the correlation on repeated measures from the same subject and that across different parts of the model. We will also discuss expansion to related topics, for example, zero-inflated count and survival data, nonlinear covariate effects, and joint models of longitudinal zero-inflated nonnegative continuous data and survival. Finally, we will present applications to three real datasets (i.e., microbiome, medical costs, and alcohol drinking) to illustrate these methods. Example code will be provided to facilitate applications of these methods. Full Article
is Comment: Empirical Bayes, Compound Decisions and Exchangeability By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Eitan Greenshtein, Ya’acov Ritov. Source: Statistical Science, Volume 34, Number 2, 224--228.Abstract: We present some personal reflections on empirical Bayes/ compound decision (EB/CD) theory following Efron (2019). In particular, we consider the role of exchangeability in the EB/CD theory and how it can be achieved when there are covariates. We also discuss the interpretation of EB/CD confidence interval, the theoretical efficiency of the CD procedure, and the impact of sparsity assumptions. Full Article
is Comment: Minimalist $g$-Modeling By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Roger Koenker, Jiaying Gu. Source: Statistical Science, Volume 34, Number 2, 209--213.Abstract: Efron’s elegant approach to $g$-modeling for empirical Bayes problems is contrasted with an implementation of the Kiefer–Wolfowitz nonparametric maximum likelihood estimator for mixture models for several examples. The latter approach has the advantage that it is free of tuning parameters and consequently provides a relatively simple complementary method. Full Article
is Gaussian Integrals and Rice Series in Crossing Distributions—to Compute the Distribution of Maxima and Other Features of Gaussian Processes By projecteuclid.org Published On :: Fri, 12 Apr 2019 04:00 EDT Georg Lindgren. Source: Statistical Science, Volume 34, Number 1, 100--128.Abstract: We describe and compare how methods based on the classical Rice’s formula for the expected number, and higher moments, of level crossings by a Gaussian process stand up to contemporary numerical methods to accurately deal with crossing related characteristics of the sample paths. We illustrate the relative merits in accuracy and computing time of the Rice moment methods and the exact numerical method, developed since the late 1990s, on three groups of distribution problems, the maximum over a finite interval and the waiting time to first crossing, the length of excursions over a level, and the joint period/amplitude of oscillations. We also treat the notoriously difficult problem of dependence between successive zero crossing distances. The exact solution has been known since at least 2000, but it has remained largely unnoticed outside the ocean science community. Extensive simulation studies illustrate the accuracy of the numerical methods. As a historical introduction an attempt is made to illustrate the relation between Rice’s original formulation and arguments and the exact numerical methods. Full Article
is Rejoinder: Response to Discussions and a Look Ahead By projecteuclid.org Published On :: Fri, 12 Apr 2019 04:00 EDT Vincent Dorie, Jennifer Hill, Uri Shalit, Marc Scott, Dan Cervone. Source: Statistical Science, Volume 34, Number 1, 94--99.Abstract: Response to discussion of Dorie (2017), in which the authors of that piece express their gratitude to the discussants, rebut some specific criticisms, and argue that the limitations of the 2016 Atlantic Causal Inference Competition represent an exciting opportunity for future competitions in a similar mold. Full Article
is Comment on “Automated Versus Do-It-Yourself Methods for Causal Inference: Lessons Learned from a Data Analysis Competition” By projecteuclid.org Published On :: Fri, 12 Apr 2019 04:00 EDT Susan Gruber, Mark J. van der Laan. Source: Statistical Science, Volume 34, Number 1, 82--85.Abstract: Dorie and co-authors (DHSSC) are to be congratulated for initiating the ACIC Data Challenge. Their project engaged the community and accelerated research by providing a level playing field for comparing the performance of a priori specified algorithms. DHSSC identified themes concerning characteristics of the DGP, properties of the estimators, and inference. We discuss these themes in the context of targeted learning. Full Article
is 'Smoking is slow-motion suicide' / Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Rd, London, SE23 ING) : Cleanair, Campaign for a Smoke-free Environment, [198-?] Full Article
is Smoking is anti-social / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
is No smoking is the norm / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
is No smoking is the norm / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
is Cleanair posters to create a smoke-free environment / designed by Biman Mullick ; published by Cleanair. By search.wellcomelibrary.org Published On :: London (33 Stillness Road, London SE23 ING) : Cleanair, [198-?] Full Article
is Smoking is bad for your image / design : Biman Mullick. By search.wellcomelibrary.org Published On :: [London?], [199-?] Full Article
is Bisher Dhoa = Bāśāra dhōyā / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London, 26 January 2003. Full Article
is Danny Smith from No Human Being Is Illegal (in all our glory). Collaged photograph by Deborah Kelly and collaborators, 2014-2018. By search.wellcomelibrary.org Published On :: [London], 2019. Full Article
is The 2019 Victoria’s Secret Fashion Show Is Canceled After Facing Backlash for Lack of Body Diversity By www.health.com Published On :: Fri, 22 Nov 2019 13:30:29 -0500 The reaction on social media has been fierce. Full Article
is Blake Lively's Favorite Affordable Jeans Brand Is Having a Major Sale Right Now By www.health.com Published On :: Mon, 25 Nov 2019 16:40:00 -0500 Here's everything you need to know about Old Navy's Black Friday and Cyber Monday plans. Full Article
is Gabrielle Union's Mesmerizing Tie Dye Activewear Set Is On Sale for Black Friday By www.health.com Published On :: Wed, 27 Nov 2019 15:35:02 -0500 The rainbow sports bra and leggings set from Splits59 is a must-have for anyone craving a pop of color in their workout wardrobe. Full Article
is Jennifer Lopez Is Wearing the Hell Out of These $60 Sneakers—and You Can Buy Them at Zappos By www.health.com Published On :: Mon, 22 Jul 2019 17:56:20 -0400 The chic sneaks are part of Zappos' massive Cyber Monday sale. Full Article
is Forget Black Booties, Amal Clooney and J.Lo Are Wearing This Weather-Resistant Boot Trend Instead By www.health.com Published On :: Tue, 10 Dec 2019 15:31:21 -0500 And it’s on sale at Nordstrom. Full Article
is This is the Only Jacket I’ll Be Living in This Winter By www.health.com Published On :: Thu, 12 Dec 2019 10:53:34 -0500 Canada Goose has long been a leader in the outdoor gear space. Full Article
is Of Course Katie Holmes Found This Year’s Coziest Winter Boot By www.health.com Published On :: Thu, 12 Dec 2019 12:51:00 -0500 Keep your feet happy this winter. Full Article
is Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization By www.jneurosci.org Published On :: 2017-05-24 Catherine MankiwMay 24, 2017; 37:5221-5231Development Plasticity Repair Full Article
is Multisensory Integration and the Society for Neuroscience: Then and Now By www.jneurosci.org Published On :: 2020-01-02 Barry E. SteinJan 2, 2020; 40:3-11Viewpoints Full Article
is Metacognitive Mechanisms Underlying Lucid Dreaming By www.jneurosci.org Published On :: 2015-01-21 Elisa FilevichJan 21, 2015; 35:1082-1088BehavioralSystemsCognitive Full Article
is Brain-Derived Neurotrophic Factor Protection of Cortical Neurons from Serum Withdrawal-Induced Apoptosis Is Inhibited by cAMP By www.jneurosci.org Published On :: 2003-06-01 Steven PoserJun 1, 2003; 23:4420-4427Cellular Full Article
is Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus By www.jneurosci.org Published On :: 2013-05-01 Timothy J. SchoenfeldMay 1, 2013; 33:7770-7777BehavioralSystemsCognitive Full Article
is Genomic Analysis of Reactive Astrogliosis By www.jneurosci.org Published On :: 2012-05-02 Jennifer L. ZamanianMay 2, 2012; 32:6391-6410Neurobiology of Disease Full Article
is Readiness Potential and Neuronal Determinism: New Insights on Libet Experiment By www.jneurosci.org Published On :: 2018-01-24 Karim FifelJan 24, 2018; 38:784-786Journal Club Full Article
is Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease By www.jneurosci.org Published On :: 2018-10-31 Subhash KulkarniOct 31, 2018; 38:9346-9354Symposium and Mini-Symposium Full Article
is Sleep Deprivation Biases the Neural Mechanisms Underlying Economic Preferences By www.jneurosci.org Published On :: 2011-03-09 Vinod VenkatramanMar 9, 2011; 31:3712-3718BehavioralSystemsCognitive Full Article
is Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control By www.jneurosci.org Published On :: 2007-02-28 William W. SeeleyFeb 28, 2007; 27:2349-2356BehavioralSystemsCognitive Full Article
is Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome By www.jneurosci.org Published On :: 2020-02-12 Irune Diaz-AparicioFeb 12, 2020; 40:1453-1482Development Plasticity Repair Full Article
is {Delta}9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism By www.jneurosci.org Published On :: 2002-06-01 Peter M. ZygmuntJun 1, 2002; 22:4720-4727Behavioral Full Article
is The Representation of Semantic Information Across Human Cerebral Cortex During Listening Versus Reading Is Invariant to Stimulus Modality By www.jneurosci.org Published On :: 2019-09-25 Fatma DenizSep 25, 2019; 39:7722-7736BehavioralSystemsCognitive Full Article
is Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults By www.jneurosci.org Published On :: 2015-01-28 Barbara J. WeilandJan 28, 2015; 35:1505-1512Neurobiology of Disease Full Article
is Fingolimod Rescues Demyelination in a Mouse Model of Krabbe's Disease By www.jneurosci.org Published On :: 2020-04-08 Sibylle BéchetApr 8, 2020; 40:3104-3118Neurobiology of Disease Full Article
is Neurobiological Mechanisms of the Placebo Effect By www.jneurosci.org Published On :: 2005-11-09 Fabrizio BenedettiNov 9, 2005; 25:10390-10402Symposia and Mini-Symposia Full Article
is Physiological Basis of Noise-Induced Hearing Loss in a Tympanal Ear By www.jneurosci.org Published On :: 2020-04-08 Ben WarrenApr 8, 2020; 40:3130-3140Neurobiology of Disease Full Article
is Where Is the Anterior Temporal Lobe and What Does It Do? By www.jneurosci.org Published On :: 2013-03-06 Michael F. BonnerMar 6, 2013; 33:4213-4215Journal Club Full Article
is Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence By www.jneurosci.org Published On :: 2019-03-06 Catherine OrrMar 6, 2019; 39:1817-1827BehavioralSystemsCognitive Full Article
is What Visual Information Is Processed in the Human Dorsal Stream? By www.jneurosci.org Published On :: 2012-06-13 Martin N. HebartJun 13, 2012; 32:8107-8109Journal Club Full Article
is Interactions of Top-Down and Bottom-Up Mechanisms in Human Visual Cortex By www.jneurosci.org Published On :: 2011-01-12 Stephanie McMainsJan 12, 2011; 31:587-597BehavioralSystemsCognitive Full Article
is Endothelial Adora2a Activation Promotes Blood-Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance By www.jneurosci.org Published On :: 2019-05-22 Masaki YamamotoMay 22, 2019; 39:4179-4192Neurobiology of Disease Full Article
is Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex By www.jneurosci.org Published On :: 2017-05-24 Michele BellesiMay 24, 2017; 37:5263-5273Cellular Full Article