mi [ASAP] Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources<subtitle>Miniperspective</subtitle> By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02126 Full Article
mi [ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00339 Full Article
mi [ASAP] A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00011 Full Article
mi [ASAP] Both <sc>d</sc>- and <sc>l</sc>-Glucose Polyphosphates Mimic <sc>d</sc>-<italic toggle="yes">myo</italic>-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00215 Full Article
mi [ASAP] Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00021 Full Article
mi [ASAP] Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00442 Full Article
mi [ASAP] Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to <italic toggle="yes">In Vivo</italic> Studies By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00431 Full Article
mi [ASAP] Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00192 Full Article
mi [ASAP] Discovery and Optimization of Glucose Uptake Inhibitors By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02153 Full Article
mi [ASAP] Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00664 Full Article
mi [ASAP] Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-<italic toggle="yes">a</italic>]pyridines against the 1A Family By feedproxy.google.com Published On :: Tue, 31 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00686 Full Article
mi [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
mi [ASAP] Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00041 Full Article
mi [ASAP] Structure Optimization of Gatastatin for the Development of ?-Tubulin-Specific Inhibitor By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00526 Full Article
mi [ASAP] Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00574 Full Article
mi [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
mi [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
mi [ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00066 Full Article
mi [ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00025 Full Article
mi [ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00028 Full Article
mi [ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00022 Full Article
mi A BEM syntax with UX in mind By simurai.com Published On :: Thu, 24 Oct 2013 00:00:00 +0000 At some point, while working on the MontageJS framework, the question came up what CSS naming convention we should start using. After a long discussion we settled on using the BEM methodology, but changed the syntax a bit. To keep this post short, I won’t go into detail why using BEM is a good idea, but rather explain why we chose a different syntax. Here some examples: .digit-Progress /* org-Component */ .digit-Progress-bar /* org-Component-childElement */ .digit-Progress--small /* org-Component--variation */ Note: The org- (digit-) prefix is used as a name-space so it wouldn’t conflict with other packages/libraries/frameworks. Now let’s take a look at the reasons for choosing such a syntax. Hyphens (-) The main reason why we’re using a hyphen (-) instead of underscores (_), has to do with the fact that their behavior is different when double-clicking to select text. Try for yourself: component__element /* underscores */ component-element /* hyphen */ See how when you’re using underscores it selects the part before and after, in this case the whole component__element. But with hyphens it let’s you select only the part you double-clicked. component OR element. This let’s you quickly edit only the parts you want: camelCase Now, what if the component or child element consists of multiple words? We could use underscores like component_name-element_name. It would still be double-clickable, but readability suffers since it’s harder to see what belongs together. Better to use camelCase which groups each part visually: componentName-elementName. MainComponent OK, I think we’re getting closer. As a last rule, for the “main” component we use PascalCase. The reason for it is to add emphasis and make it easier to distinguish the main component from a child element. Also when using a namespace, the component moves to the second position, which makes it even more important to have it stick out: org-Component-childElement –variation We kept the more commonly used double hyphens (–) for variations. digit-Progress--small. It makes sense, because it pulls the variation (–small) visually more apart and makes it look like it’s something “different” than the default component. So that’s about it. For more details about this naming convention, take a look at the SUIT framework, which also started to use the same syntax and documented it really well. In the end, whatever Shade of BEM you choose to cook with probably depends on your personal taste, but thinking about a great UX by improving usability and readability won’t hurt either. Full Article
mi The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - NE538.N5 W49 2019 Full Article
mi Huguette Caland / edited by Anne Barlow, Sara Matson and Giles Jackson ; texts by Anne Barlow, Brigitte Caland and Negar Azimi By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6537.C329 A4 2019 Full Article
mi Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6260.K87 2019 Full Article
mi Usṭūrahʹhā va namādʹhā-yi āyinī dar nigārahʹhā-yi Saqānifārʹhā-yi Māzandarān / taʼlīf va gurdʹāvarī-i Muṣṭafá Rustamī, Fāṭimah Bābājānʹtabār Nashlī By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N7280.R888 2018 Full Article
mi Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8251.S555 A48 2018 Full Article
mi Beatriz Milhazes: rio azul / White Cube By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6659.M55 A4 2018 Full Article
mi Fogo Island arts: what do we know? What do we have? What do we miss? What do we love? / Brigitte Oetker, Nicolaus Schafhausen (eds.) By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6546.N6 F64 2019 Full Article
mi Design by accident: for a new history of design / Alexandra Midal By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NK1175.M53 2019 Full Article
mi Unfinished conversations on the weight of absence: Belu-Simion Făinaru, Dan Mihălțianu, Miklós Onucsán / curator, Cristian Nae By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 R6 Full Article
mi Conversation pieces: the world of Bruegel / Abdelkader Benali, Alexandra van Dongen, Katrien Lichtert, Sabine Pénot, Lucinda Timmermans ; translation, Patrick Lennon, Michael Lomax By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND673.B73 B46 2018 Full Article
mi Mary Corse: a survey in light / Kim Conaty ; with contributions from Robin Clark, Michael Govan, Alexis Lowry, and David Reed By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6537.C663 A4 2018 Full Article
mi Per Kirkeby / herausgegeben von Florian Steininger ; mit Beiträgen von Robert Fleck, Per Kirkeby, Florian Steininger By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND723.K53 A4 2018 Full Article
mi Illuminated Paris: essays on art and lighting in the belle époque / Hollis Clayson By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8214.5.F8 C539 2019 Full Article
mi Studies in Armenian art: collected papers / by Nira Stone ; edited by Michael E. Stone, Asya Bereznyak By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7274.S76 2019 Full Article
mi For want of a nail / Amy Franceschini & Michael Swaine, Futurefarmers By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7433.4.F73 F67 2019 Full Article
mi Sound, image, silence: art and the aural imagination in the Atlantic world / Michael Gaudio By library.mit.edu Published On :: Sun, 1 Mar 2020 06:00:02 EST Online Resource Full Article
mi Encyclopedia of the Black Arts Movement / edited by Verner D. Mitchell, Cynthia Davis By library.mit.edu Published On :: Sun, 1 Mar 2020 06:00:02 EST Online Resource Full Article
mi The lady from the black lagoon: Hollywood monsters and the lost legacy of Milicent Patrick / Mallory O'Meara By library.mit.edu Published On :: Sun, 1 Mar 2020 06:00:02 EST Dewey Library - NC1766.U52 P38 2019 Full Article
mi Inspired by the East: how the Islamic world influenced Western art / edited by William Greenwood, Lucien de Guise By library.mit.edu Published On :: Sun, 1 Mar 2020 06:00:02 EST Rotch Library - ND1460.E95 I57 2019 Full Article
mi What is "Islamic" art?: between religion and perception / Wendy M.K. Shaw By library.mit.edu Published On :: Sun, 8 Mar 2020 06:00:02 EDT Rotch Library - N6260.S56 2019 Full Article
mi Expanded internet art: twenty-first century artistic practice and the informational milieu / Ceci Moss By library.mit.edu Published On :: Sun, 8 Mar 2020 06:00:02 EDT Rotch Library - N7433.8.M67 2019 Full Article
mi Trouble with women artists: reframing the history of art / Laure Adler & Camille Viéville ; translated from the French by Kate Robinson By library.mit.edu Published On :: Sun, 15 Mar 2020 06:00:01 EDT Rotch Library - N8354.A3513 2019 Full Article
mi The grammar of pattern / Michael Hann By library.mit.edu Published On :: Sun, 15 Mar 2020 06:00:01 EDT Online Resource Full Article
mi Inside Tangier: houses & gardens / Nicolò Castellini Baldissera ; photography, Guido Taroni ; foreword, Hamish Bowles By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - NK2087.75.A1 B35 2019 Full Article
mi Arabicity: contemporary Arab art / edited by Rose Issa and Juliet Cestar ; contributions by Rose Issa, Georges Corm, Michket Krifa, Etel Adnan By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - N7265.3.A733 2019 Full Article
mi Shirin Neshat: I will greet the sun again / organized by Ed Schad ; Shirin Neshat in conversation with Glenn Lowry ; with essays by Godfrey Cheshire, Layla S. Diba, Farzaneh Milani, and Ed Schad By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - TR647.N4454 2019 Full Article
mi Bauhaus futures / edited by Laura Forlano, Molly Wright Steenson, and Mike Ananny By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - NK1505.B38 2019 Full Article
mi Casa Wabi / Tadao Ando, Gloria Cabral and Solano Benítez, Damián Comas for Jorge Ambrosi and Gabriela Etchegaray, Dakin Hart, Alberto Kalach, Kengo Kuma, Alfonso Quiñones, Alberto Ríos de la Rosa, Álvaro Siza, Bosco Sodi, Carla S By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - N8520.A53 2018 Full Article