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[ASAP] Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources<subtitle>Miniperspective</subtitle>

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02126




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[ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00339




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[ASAP] A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00011




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[ASAP] Both <sc>d</sc>- and <sc>l</sc>-Glucose Polyphosphates Mimic <sc>d</sc>-<italic toggle="yes">myo</italic>-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00215




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[ASAP] Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00021




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[ASAP] Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00442




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[ASAP] Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to <italic toggle="yes">In Vivo</italic> Studies

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00431




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[ASAP] Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00192




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[ASAP] Discovery and Optimization of Glucose Uptake Inhibitors

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02153




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[ASAP] Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00664




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[ASAP] Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-<italic toggle="yes">a</italic>]pyridines against the 1A Family

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00686




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[ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00669




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[ASAP] Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00041




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[ASAP] Structure Optimization of Gatastatin for the Development of ?-Tubulin-Specific Inhibitor

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00526




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[ASAP] Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00574




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[ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00131




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[ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00095




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[ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00066




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[ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00025




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[ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00028




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[ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00022




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A BEM syntax with UX in mind

At some point, while working on the MontageJS framework, the question came up what CSS naming convention we should start using. After a long discussion we settled on using the BEM methodology, but changed the syntax a bit. To keep this post short, I won’t go into detail why using BEM is a good idea, but rather explain why we chose a different syntax. Here some examples:

.digit-Progress          /* org-Component */
.digit-Progress-bar      /* org-Component-childElement */
.digit-Progress--small   /* org-Component--variation */

Note: The org- (digit-) prefix is used as a name-space so it wouldn’t conflict with other packages/libraries/frameworks.

Now let’s take a look at the reasons for choosing such a syntax.

Hyphens (-)

The main reason why we’re using a hyphen (-) instead of underscores (_), has to do with the fact that their behavior is different when double-clicking to select text. Try for yourself:

component__element /* underscores */
component-element  /* hyphen */

See how when you’re using underscores it selects the part before and after, in this case the whole component__element. But with hyphens it let’s you select only the part you double-clicked. component OR element. This let’s you quickly edit only the parts you want:

camelCase

Now, what if the component or child element consists of multiple words? We could use underscores like component_name-element_name. It would still be double-clickable, but readability suffers since it’s harder to see what belongs together. Better to use camelCase which groups each part visually: componentName-elementName.

MainComponent

OK, I think we’re getting closer. As a last rule, for the “main” component we use PascalCase. The reason for it is to add emphasis and make it easier to distinguish the main component from a child element. Also when using a namespace, the component moves to the second position, which makes it even more important to have it stick out: org-Component-childElement

–variation

We kept the more commonly used double hyphens (–) for variations. digit-Progress--small. It makes sense, because it pulls the variation (–small) visually more apart and makes it look like it’s something “different” than the default component.


So that’s about it. For more details about this naming convention, take a look at the SUIT framework, which also started to use the same syntax and documented it really well.

In the end, whatever Shade of BEM you choose to cook with probably depends on your personal taste, but thinking about a great UX by improving usability and readability won’t hurt either.




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The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl

Rotch Library - NE538.N5 W49 2019




mi

Huguette Caland / edited by Anne Barlow, Sara Matson and Giles Jackson ; texts by Anne Barlow, Brigitte Caland and Negar Azimi

Rotch Library - N6537.C329 A4 2019




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Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller

Rotch Library - N6260.K87 2019




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Usṭūrahʹhā va namādʹhā-yi āyinī dar nigārahʹhā-yi Saqānifārʹhā-yi Māzandarān / taʼlīf va gurdʹāvarī-i Muṣṭafá Rustamī, Fāṭimah Bābājānʹtabār Nashlī

Rotch Library - N7280.R888 2018




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Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others]

Rotch Library - N8251.S555 A48 2018




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Beatriz Milhazes: rio azul / White Cube

Rotch Library - N6659.M55 A4 2018




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Fogo Island arts: what do we know? What do we have? What do we miss? What do we love? / Brigitte Oetker, Nicolaus Schafhausen (eds.)

Rotch Library - N6546.N6 F64 2019




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Design by accident: for a new history of design / Alexandra Midal

Rotch Library - NK1175.M53 2019




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Unfinished conversations on the weight of absence: Belu-Simion Făinaru, Dan Mihălțianu, Miklós Onucsán / curator, Cristian Nae

Rotch Library - N6488.I8 V433 2019 R6




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Conversation pieces: the world of Bruegel / Abdelkader Benali, Alexandra van Dongen, Katrien Lichtert, Sabine Pénot, Lucinda Timmermans ; translation, Patrick Lennon, Michael Lomax

Rotch Library - ND673.B73 B46 2018




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Mary Corse: a survey in light / Kim Conaty ; with contributions from Robin Clark, Michael Govan, Alexis Lowry, and David Reed

Rotch Library - N6537.C663 A4 2018




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Per Kirkeby / herausgegeben von Florian Steininger ; mit Beiträgen von Robert Fleck, Per Kirkeby, Florian Steininger

Rotch Library - ND723.K53 A4 2018




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Illuminated Paris: essays on art and lighting in the belle époque / Hollis Clayson

Rotch Library - N8214.5.F8 C539 2019




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Studies in Armenian art: collected papers / by Nira Stone ; edited by Michael E. Stone, Asya Bereznyak

Rotch Library - N7274.S76 2019




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For want of a nail / Amy Franceschini & Michael Swaine, Futurefarmers

Rotch Library - N7433.4.F73 F67 2019




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Sound, image, silence: art and the aural imagination in the Atlantic world / Michael Gaudio

Online Resource




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Encyclopedia of the Black Arts Movement / edited by Verner D. Mitchell, Cynthia Davis

Online Resource




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The lady from the black lagoon: Hollywood monsters and the lost legacy of Milicent Patrick / Mallory O'Meara

Dewey Library - NC1766.U52 P38 2019




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Inspired by the East: how the Islamic world influenced Western art / edited by William Greenwood, Lucien de Guise

Rotch Library - ND1460.E95 I57 2019




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What is "Islamic" art?: between religion and perception / Wendy M.K. Shaw

Rotch Library - N6260.S56 2019




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Expanded internet art: twenty-first century artistic practice and the informational milieu / Ceci Moss

Rotch Library - N7433.8.M67 2019




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Trouble with women artists: reframing the history of art / Laure Adler & Camille Viéville ; translated from the French by Kate Robinson

Rotch Library - N8354.A3513 2019




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The grammar of pattern / Michael Hann

Online Resource




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Inside Tangier: houses & gardens / Nicolò Castellini Baldissera ; photography, Guido Taroni ; foreword, Hamish Bowles

Rotch Library - NK2087.75.A1 B35 2019




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Arabicity: contemporary Arab art / edited by Rose Issa and Juliet Cestar ; contributions by Rose Issa, Georges Corm, Michket Krifa, Etel Adnan

Rotch Library - N7265.3.A733 2019




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Shirin Neshat: I will greet the sun again / organized by Ed Schad ; Shirin Neshat in conversation with Glenn Lowry ; with essays by Godfrey Cheshire, Layla S. Diba, Farzaneh Milani, and Ed Schad

Rotch Library - TR647.N4454 2019




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Bauhaus futures / edited by Laura Forlano, Molly Wright Steenson, and Mike Ananny

Rotch Library - NK1505.B38 2019




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Casa Wabi / Tadao Ando, Gloria Cabral and Solano Benítez, Damián Comas for Jorge Ambrosi and Gabriela Etchegaray, Dakin Hart, Alberto Kalach, Kengo Kuma, Alfonso Quiñones, Alberto Ríos de la Rosa, Álvaro Siza, Bosco Sodi, Carla S

Rotch Library - N8520.A53 2018