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A signal cascade amplification strategy based on RT-PCR triggering of G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00270D, Paper
Yuanyuan Yuan, Xianyong Wu, Zhanmin Liu, QIqi Ning, Liqiang Fu, Sujuan Wu
Cronobacter sakazakii is an important opportunistic food-borne pathogen, and it can cause severe diseases with main symptoms including neonatal meningitis, necrotizing enterocolitis, and sepsis. For the achievement of practical and...
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iso-μmGene: Isothermal amplification-based portable microfluidic system for simple, reliable and flexibly multiplexed Genetic identification and quantification

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00560F, Paper
Runtao Zhong, Shilin Liu, Guohao Zhang, Mengyu Wang, Yeqing Sun
Simple, reliable and flexibly multiplexed genetic identification and quantification of microbial pathogens is in urgent need for early disease diagnosis and timely treatment. This study presented an isothermal amplification-based portable...
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Rapid and accurate identification of marine microbes with single-cell Raman spectroscopy

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Analyst, 2020, 145,3297-3305
DOI: 10.1039/C9AN02069A, Paper
Yaoyao Liu, Jingjing Xu, Yi Tao, Teng Fang, Wenbin Du, Anpei Ye
Rapid and accurate identification of individual microorganisms using single-cell Raman spectra combining with one-dimensional convolutional neural networks.
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A disposable molecularly imprinted electrochemical sensor for the ultra-trace detection of the organophosphorus insecticide phosalone employing monodisperse Pt-doped UiO-66 for signal amplification

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Analyst, 2020, 145,3245-3256
DOI: 10.1039/D0AN00278J, Paper
Liping Xu, Jiebin Li, Jiajia Zhang, Junyong Sun, Tian Gan, Yanming Liu
A disposable electrochemical sensor was fabricated based on monodisperse Pt-doped UiO-66 and a mesoporous molecularly imprinted polymer to specifically detect phosalone.
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Electrochemiluminescence analysis of tryptophan in aqueous solutions based on its reaction with tetraphenylborate anions

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Analyst, 2020, 145,3364-3369
DOI: 10.1039/D0AN00229A, Paper
Yuriy Zholudov, Natalia Lysak, Dmytro Snizhko, Olena Reshetniak, Guobao Xu
A pulsed electrogenerated chemiluminescence is observed upon the oxidation of tryptophan amino acid in aqueous solutions with a tetraphenylborate co-reactant.
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An ultrasensitive electrochemiluminescence aptasensor for the detection of diethylstilbestrol based on the enhancing mechanism of the metal–organic framework NH2-MIL-125(Ti) in a 3,4,9,10-perylenetetracarboxylic acid/K2S2O8 system

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Analyst, 2020, 145,3306-3312
DOI: 10.1039/D0AN00212G, Paper
Jingxian Li, Xueling Shan, Ding Jiang, Zhidong Chen
A novel electrochemiluminescence (ECL) aptasensor based on PTCA/NH2-MIL-125 for the determination of diethylstilbestrol.
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An electrochemical sensor based on enzyme-free recycling amplification for sensitive and specific detection of miRNAs from cancer cells

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Analyst, 2020, 145,3353-3358
DOI: 10.1039/D0AN00275E, Paper
Lili Jiang, Yuling Yang, Yuhong Lin, Ziyi Chen, Chao Xing, Chunhua Lu, Huanghao Yang, Shusheng Zhang
A catalyzed hairpin assembly and binding-induced formation of the DNA three-way junction for ultrasensitive electrochemical detection of diverse miRNAs is reported.
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Trace manganese detection via differential pulse cathodic stripping voltammetry using disposable electrodes: additively manufactured nanographite electrochemical sensing platforms

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Analyst, 2020, 145,3424-3430
DOI: 10.1039/D0AN00018C, Paper
Open Access
Diego P. Rocha, Christopher W. Foster, Rodrigo A. A. Munoz, Gary A. Buller, Edmund M. Keefe, Craig E. Banks
Additive manufacturing is a promising technology for the rapid and economical fabrication of portable electroanalytical devices.
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An ionic-based carbon dot for enantioselective discrimination of nonaromatic amino alcohols

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Analyst, 2020, 145,3395-3400
DOI: 10.1039/D0AN00399A, Paper
Datong Wu, Fei Pan, Li Gao, Yongxin Tao, Yong Kong
An ionic chiral carbon dot was designed and synthesized for the chiral recognition of nonaromatic amino alcohols.
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Paper-based platforms with coulometric readout for ascorbic acid determination in fruit juices

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Analyst, 2020, 145,3431-3439
DOI: 10.1039/D0AN00477D, Paper
Estefanía Nunez-Bajo, M. Teresa Fernández-Abedul
Paper-based electrochemical platforms with coulometric readout are employed for fast and low cost determination of ascorbic acid in commercial juice samples.
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In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis

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Analyst, 2020, 145,3289-3296
DOI: 10.1039/D0AN00393J, Paper
Huizhen Wang, Dinggeng He, Kejing Wan, Xiaowu Sheng, Hong Cheng, Jin Huang, Xiao Zhou, Xiaoxiao He, Kemin Wang
Herein, a simple all-in-one biosensor based on a DNA three-way junction has been constructed for in situ simultaneous detection of multiple miRNAs by competitive strand displacement.
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Novel ratiometric electrochemical sensor for no-wash detection of fluorene-9-bisphenol based on combining CoN nanoarrays with molecularly imprinted polymers

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Analyst, 2020, 145,3320-3328
DOI: 10.1039/D0AN00345J, Paper
Zhaoyi Liu, Yong Zhang, Bing Li, Xiang Ren, Hongmin Ma, Qin Wei
A ratiometric molecularly imprinted polymers electrochemical sensor was fabricated based on the direct electrochemical oxidation of BHPF on CoN nanoarray electrode.
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Using the interfacial barrier effects of p–n junction on electrochemistry for detection of phosphate

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Analyst, 2020, 145,3217-3221
DOI: 10.1039/C9AN02579K, Communication
Yu Ding, Minggang Zhao, Jiatuo Yu, Xiaomin Zhang, Zhengming Li, Hui Li
The electrochemical response to phosphate was produced by the induced change of the interfacial barrier of the NiO/ZnO p–n junction foam.
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Rapid detection of 21 β-lactams using an immunochromatographic assay based on the mutant BlaR-CTD protein from Bacillus Licheniformis

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Analyst, 2020, 145,3257-3265
DOI: 10.1039/D0AN00421A, Paper
Yue Li, Xinxin Xu, Liqiang Liu, Hua Kuang, Liguang Xu, Chuanlai Xu
In this study, a gold immunochromatographic assay (GICA) based on a penicillin receptor protein (PBP) is proposed to simultaneously detect penicillin, cephalosporin, and carbapenem antibiotics in milk and chicken.
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Synthesis of a manganese dioxide nanorod-anchored graphene oxide composite for highly sensitive electrochemical sensing of dopamine

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Analyst, 2020, 145,3283-3288
DOI: 10.1039/D0AN00348D, Paper
Juan Li, Huifang Shen, Suhua Yu, Geshan Zhang, Chuanli Ren, Xiaoya Hu, Zhanjun Yang
A novel manganese dioxide nanorod-anchored graphene oxide (MnO2 NRs/GO) composite was synthesized by a simple hydrothermal method for the development of a highly sensitive electrochemical sensor for dopamine.
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Direct embedding and versatile placement of electrodes in 3D printed microfluidic-devices

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Analyst, 2020, 145,3274-3282
DOI: 10.1039/D0AN00240B, Paper
Andre D. Castiaux, Emily R. Currens, R. Scott Martin
In this paper, we describe how PolyJet 3D printing technology can be used to fully integrate electrode materials into microfluidic devices during the print process.
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Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent

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Published On ::

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00288G, Paper
Joohee Park, Hyeongseok Yu, See-Hyoung Park, Keun-Hyeung Lee
A ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.
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A highly efficient preconcentration route for rapid and sensitive detection of endotoxin based on an electrochemical biosensor

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Published On ::

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00315H, Paper
Wenrui Ma, Lulu Liu, Yi Xu, Li Wang, Li Chen, Sheng Yan, Lingling Shui, Zhijun Wang, Shunbo Li
An impedimetric aptasensor for detection of endotoxin in a microfluidic chip was proposed, in which the Apt/AuNPs/SPCE sensing surface was fabricated in screen-printed electrode with good biological activity and stability....
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Plasmonic Nanobiosensors for Detection of MicroRNA Cancer Biomarkers in Clinical Samples

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00193G, Paper
Bridget M Crawford, Hsin-Neng Wang, Christina Stolarchuk, Richard Von Furstenberg, Pietro Strobbia, dadong zhang, xiaodi qin, kouros owzar, katherine garman, Vo-Dinh Tuan
MicroRNA (miRNA) play an important role in the regulation of biological processes and have demonstrated great promise as biomarkers for the early detection of various diseases, including esophageal adenocarcinoma (EAC)...
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Laser-induced graphene hybrid photoelectrode for enhanced photoelectrochemical detection of glucose

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00252F, Paper
Hui Li, Chengxiang Guo, Changchun Liu, Lei Ge, Feng Li
The in situ and synchronous fabrication of Ni0/NiO–CdS–graphene hybrid photoelectrodes is developed using a facile and scalable direct-laser-writing method for photoelectrochemical detection of glucose.
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An electrochemical biosensor based on methylene blue-loaded nanocomposites as signal-amplifying tags to detect pathogenic bacteria

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00470G, Paper
Shengjun Bu, Kuiyu Wang, Zhongyi Li, Chengyu Wang, Zhuo Hao, Wensen Liu, Jiayu Wan
Synthesis of new methylene blue–magainin I organic–inorganic nanocomposites as electrochemical signal labels for the detection of bacteria.
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A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00302F, Paper
Xinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian Wang
A homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.
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Scientific workflow managers in metabolomics: an overview

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00272K, Critical Review
Aswin Verhoeven, Martin Giera, Oleg A. Mayboroda
Metabolomics workflows for data processing reproducibility and accelerated clinical deployment.
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Tetrahedral DNA Nanostructure-decorated Electrochemical Platform for Simple and Ultrasensitive EGFR Genotyping of Plasma ctDNA

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00591F, Paper
Xuyao Wang, Jianping Wu, Weilin Mao, Xia He, Liming Ruan, Junlan Zhu, Peng Shu, Zhenqi Zhang, Bitao Jiang, Xingguo Zhang
Genotyping of the epidermal growth factor receptor (EGFR) mutation status is of great importance in the screening of appropriate advanced non-small cell lung carcinoma (NSCLC) patients to receive superior tyrosine...
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Magnetic molecularly imprinted conducting polymer for determination of praziquantel enantiomers in milk

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00703J, Paper
Tienne Nascimento, Camilla Fonseca Silva, Hanna L Oliveira, Ricky Cássio Santos da Silva, Clébio Soares Nascimento, Keyller Bastos Borges
A new selective adsorbent based on magnetic molecularly imprinted conducting polymer was firstly synthetized and applied to the magnetic solid phase extraction (MSPE) for the determination of PZQ enantiomers in...
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A paper-supported sandwich immunosensor based on upconversion luminescence resonance energy transfer for the visual and quantitative determination of a cancer biomarker in human serum

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/C9AN02307K, Paper
Mengyuan He, Ning Shang, Lin Shen, Zhi-hong Liu
In this paper, a paper-supported analytical device based on a sandwich immunoreaction and luminescence resonance energy transfer (LRET) was reported for the visual and quantitative determination of a cancer biomarker,...
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An Integrated Microfluidic Platform for Selective and Real-Time Detection of Thrombin Biomarkers using a Graphene FET

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Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00251H, Paper
Niazul Islam Khan, Mohammad Mousazadehkasin, Sujoy Ghosh, John G. Tsavalas, Edward Song
Lab-on-a-chip technology offers an ideal platform for low-cost, reliable, and easy-to-use diagnostics of key biomarkers needed for early screening of diseases and other health concerns. In this work, a graphene...
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Core–shell magnetic microporous covalent organic framework with functionalized Ti(IV) for selective enrichment of phosphopeptides

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00038H, Paper
Fengjuan Ding, Yameng Zhao, Haiyan Liu, Weibing Zhang
We fabricated a core-shell magnetic Ti4+-functionalized covalent organic framework composite to selectively capture phosphopeptides in biosamples. This method is applicable to achieve rapid, selective and efficient phosphopeptide analysis.
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Acid–base titration using a microfluidic thread-based analytical device (μTAD)

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Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00522C, Paper
Purim Jarujamrus, Akarapong Prakobkij, Sodsai Puchum, Sawida Chaisamdaeng, Rattapol Meelapsom, Wipark Anutrasakda, Maliwan Amatatongchai, Sanoe Chairam, Daniel Citterio
This work presents a novel analytical approach for precise and quick (within 2 minutes) determination of acid and base concentrations (of very small amount) by titration using a microfluidic thread-based analytical device (μTAD).
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[ASAP] A Coculture Based Tyrosine-Tyrosinase Electrochemical Gene Circuit for Connecting Cellular Communication with Electronic Networks

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Published On :: Thu, 02 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00469


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[ASAP] Determinants for Efficient Editing with Cas9-Mediated Recombineering in <italic toggle="yes">Escherichia coli</italic>

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Published On :: Tue, 28 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00440


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[ASAP] Facilitating Protein Expression with Portable 5'-UTR Secondary Structures in <italic toggle="yes">Bacillus licheniformis</italic>

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00355


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[ASAP] MAPPS: A Web-Based Tool for Metabolic Pathway Prediction and Network Analysis in the Postgenomic Era

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00397


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[ASAP] Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in <italic toggle="yes">E. coli</italic> Nissle Residing in the Mammalian Gut

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00040


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[ASAP] A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology

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Published On :: Thu, 30 Apr 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00476


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[ASAP] Multicomponent Microscale Biosynthesis of Unnatural Cyanobacterial Indole Alkaloids

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Published On :: Thu, 07 May 2020 04:00:00 GMT

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00038


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[ASAP] MymA Bioactivated Thioalkylbenzoxazole Prodrug Family Active against <italic toggle="yes">Mycobacterium tuberculosis</italic>

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Published On :: Sun, 19 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00003


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[ASAP] Imidazo[1,2-<italic toggle="yes">a</italic>]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells

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Published On :: Mon, 20 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01910


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[ASAP] Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy

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Published On :: Tue, 21 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01961


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[ASAP] Metabolism and Bioactivation: It’s Time to Expect the Unexpected<subtitle>Miniperspective</subtitle>

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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00026


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[ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy

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Published On :: Tue, 21 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00280


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[ASAP] Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation

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Published On :: Wed, 22 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00035


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[ASAP] Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

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Published On :: Thu, 23 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01835


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[ASAP] Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma

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Published On :: Thu, 23 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02161


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[ASAP] Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design

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Published On :: Fri, 24 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02092


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[ASAP] Discovery of (2<italic toggle="yes">R</italic>)-<italic toggle="yes">N</italic>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<italic toggle="yes">H</italic>-indol-7

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Published On :: Tue, 28 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01392


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[ASAP] Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

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Published On :: Tue, 28 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01336


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[ASAP] Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00015


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[ASAP] Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting

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Published On :: Thu, 30 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01936


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[ASAP] Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions

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Published On :: Fri, 01 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01937


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