Adaptive coding of stimuli is well documented in perception, where it supports efficient encoding over a broad range of possible percepts. Recently, a similar neural mechanism has been reported also in value-based decision, where it allows optimal encoding of vast ranges of values in PFC: neuronal response to value depends on the choice context (relative coding), rather than being invariant across contexts (absolute coding). Additionally, value learning is sensitive to the amount of feedback information: providing complete feedback (both obtained and forgone outcomes) instead of partial feedback (only obtained outcome) improves learning. However, it is unclear whether relative coding occurs in all PFC regions and how it is affected by feedback information. We systematically investigated univariate and multivariate feedback encoding in various mPFC regions and compared three modes of neural coding: absolute, partially-adaptive and fully-adaptive.

Twenty-eight human participants (both sexes) performed a learning task while undergoing fMRI scanning. On each trial, they chose between two symbols associated with a certain outcome. Then, the decision outcome was revealed. Notably, in one-half of the trials participants received partial feedback, whereas in the other half they got complete feedback. We used univariate and multivariate analysis to explore value encoding in different feedback conditions.

We found that both obtained and forgone outcomes were encoded in mPFC, but with opposite sign in its ventral and dorsal subdivisions. Moreover, we showed that increasing feedback information induced a switch from absolute to relative coding. Our results suggest that complete feedback information enhances context-dependent outcome encoding.

SIGNIFICANCE STATEMENT This study offers a systematic investigation of the effect of the amount of feedback information (partial vs complete) on univariate and multivariate outcome value encoding, within multiple regions in mPFC and cingulate cortex that are critical for value-based decisions and behavioral adaptation. Moreover, we provide the first comparison of three possible models of neural coding (i.e., absolute, partially-adaptive, and fully-adaptive coding) of value signal in these regions, by using commensurable measures of prediction accuracy. Taken together, our results help build a more comprehensive picture of how the human brain encodes and processes outcome value. In particular, our results suggest that simultaneous presentation of obtained and foregone outcomes promotes relative value representation.

Recent literature has highlighted that international trade is mostly priced in a few key vehicle currencies, and is increasingly dominated by intermediate goods and global value chains (GVCs). Taking these features into account, this paper reexamines the business cycle dynamics of international trade and its relationship with monetary policy and exchange rates.

Remarks by Benoît Cœuré, Head of the Bank for International Settlements Innovation Hub, at the Reinventing Bretton Woods Committee - Chamber of Digital Commerce webinar on "The world economy transformed", 17 April 2020.

Bank for International Settlements BIS Working Papers by David Cook and Nikhil Patel

The post The Value of Simulation: Which Design is the Best? appeared first on The SOLIDWORKS Blog.

The post The Value of a “Body Double” During the Coronavirus Pandemic appeared first on The SOLIDWORKS Blog.

The post Learn the Value of Simulation in our Webinar Series appeared first on The SOLIDWORKS Blog.

OM Guatemala visits primary and secondary schools in the country to teach children values and bring them the good news.

Workers encourage new believers to persevere in their faith despite facing persecution from their families.

A pair of new studies find that, when given a choice, white parents tend to send their children to schools that are predominantly white.

The Houston school district has settled a federal lawsuit brought by the teacher's union over the school system's controversial teacher evaluation system, which involved a secret algorithm.

Aluminum is ubiquitous and exposure is unavoidable. Adverse health effects have been associated with large exposures in workers or those with chronic kidney disease. There are no established age-specific reference ranges or toxicity data for populations of healthy children.

We demonstrate the wide variability of aluminum reference ranges in biological samples and that the ranges are not based on studies including healthy children. Further research is necessary to establish clinically relevant reference ranges for healthy children. (Read the full article)

The medical home is associated with beneficial outcomes in children with special health care needs and in the entire pediatric population. It is unknown if it benefits the majority of the pediatric population (ie, children without special health care needs).

This study is the first to demonstrate an association between the medical home and beneficial health care utilization, child health, and health-promoting behavior outcomes in children without special health care needs. (Read the full article)

Three-fourths of US preschool-age children are in child care; many are not achieving recommended levels of physical activity. Daily physical activity is essential for motor and socioemotional development and for the prevention of obesity. Little is known about physical-activity barriers in child care.

Injury and school-readiness concerns may inhibit children’s physical activity in child care. Fixed playground equipment that meets licensing codes is unchallenging and uninteresting to children. Centers may cut time and space for gross motor play to address concerns about school readiness. (Read the full article)

Newborn screening (NBS) programs may store bloodspot samples and use them for secondary purposes, such as research. Recent public controversies and lawsuits over storage and secondary uses underscore the need to engage the public on these issues.

This public engagement study identifies values underlying citizens’ acceptance of and discomfort with research from NBS samples. Well-designed methods of public education and civic discourse on the risks and benefits of storage and secondary uses of NBS samples are required. (Read the full article)

Although follow-up examinations are recommended for suspected victims of sexual abuse or assault, little is known about the potential benefits of a second examination with regard to diagnosing trauma or sexually transmitted infections.

In ~23% of pediatric patients evaluated for sexual abuse or assault, a second examination by a specialist changed the interpretation of trauma likelihood or results in the detection of a sexually transmitted infection. (Read the full article)

Percentile charts for birth weight are used to assess the somatic development of neonates (small, appropriate, or large for gestational age).

A systematic error was identified in the majority of birth weight percentile charts. As a consequence, small for gestational age rates are overestimated and large for gestational age rates are underestimated; ~5% of neonates are misclassified. (Read the full article)

Biomarkers such as C-reactive protein (CRP) and procalcitonin are elevated in children with severe bacterial infections. Children with severe malnutrition are at increased risk of bacterial infections and early markers for the diagnosis of infection in these children are needed.

Despite elevated values in severely malnourished children with invasive bacterial infection or infectious diarrhea, CRP and procalcitonin have limited diagnostic value. CRP could predict death in these children with a good negative predictive value. (Read the full article)

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for drugs that can more efficiently treat these brain infections remains. A crucial step in drug development is the evaluation of in vivo drug efficacy in animal models. This mainly relies on survival studies or post-mortem analyses in large groups of animals, but these techniques only provide information on specific organs of interest at predefined time points. In this proof-of-concept study, we validated the use of non-invasive preclinical imaging to obtain longitudinal information on the therapeutic efficacy of amphotericin B or fluconazole monotherapy in meningoencephalitis and cryptococcoma mouse models. Bioluminescence imaging (BLI) enabled the rapid in vitro and in vivo evaluation of drug efficacy while complementary high-resolution anatomical information obtained by magnetic resonance imaging (MRI) of the brain allowed a precise assessment of the extent of infection and lesion growth rates. We demonstrated a good correlation between both imaging readouts and the fungal burden in various organs. Moreover, we identified potential pitfalls associated with the interpretation of therapeutic efficacy based solely on post-mortem studies, demonstrating the added value of this non-invasive dual imaging approach compared to standard mortality curves or fungal load endpoints. This novel preclinical imaging platform provides insights in the dynamic aspects of the therapeutic response and facilitates a more efficient and accurate translation of promising antifungal compounds from bench to bedside.

Delaware’s Department of Insurance is pleased to announce that it is actively recruiting for a qualified independent contractor to staff and run its new Office of Value-Based Health Care Delivery. The Office will assist the Insurance Commissioner and Delaware’s Primary Care Reform Collaborative in evaluating primary care accessibility and affordability statewide. “Reducing health care costs […]

If You Want a Job in Web Desing, Web Developemnt, Software Development, Link Building, Multimedia, Networking. Do not Wait Apply Online Jobs in H K Digital Online

NEW CASTLE (Nov. 15, 2018) – As part of the State Innovation Model (SIM) initiative, the Delaware Health Care Commission has awarded the first value-based payment reform mini-grant to Christiana Care Health System to test a new reimbursement model that will also improve the coordination of patient care. Christiana Care Health System’s CareLink Behavioral Health […]

NEW CASTLE (Dec. 4, 2018) – As part of the State Innovation Model (SIM) initiative, the Delaware Health Care Commission has awarded eight additional value-based payment reform mini-grants to Delaware health care providers in order to facilitate data integration, improve the coordination of patient care or increase readiness to integrate into an Accountable Care Organization […]

Life insurance claims to the extent of basic sum assured if policyholder dies due to infection by the corona virus is admissible.

Now is the time to assess where you are in relation to financial goals, tax planning & cash inflows.

Ladies and gentlemen, I give you Value-Based Payments (VBP), health care’s new magic, “silver bullet” that will solve all our fraud problems. Last month, the US Department of Health and Human Services (HHS) issued a press release entitled, “HHS Proposes Stark Law and Anti-Kickback Statute Reforms to Support Value-Based and [...]

The post Fighting fraud in the new world of Value-Based Payments appeared first on Government Data Connection.

I've previously written about how to generate points that are uniformly distributed in the unit disk. A seemingly unrelated topic is the distribution of eigenvalues (in the complex plane) of various kinds of random matrices. However, I recently learned that these topics are somewhat related! A mathematical result called the [...]

The post The circular law for eigenvalues appeared first on The DO Loop.

When I place a pcell and do not change the W parameter (default is used) the value is not saved in the OA cell property.

When I change the default value of the super master now, the old pcell will get the new default value automatically because there is nothing saved inside the OA cell for this parameter.

Do you have any Idea, that how we can save the default values in the OA cell properties so that this value doesn't get updated if the default values are updated in the new PDKs

Hi, I want to add values to components in my SiP design such as 1nF or 15nH. There is already in existence a COMP_VALUE property reserved for this as shown during BOM generation. This property is not visible under the Edit/Properties dialog for component or symbol find filters. We have already created user properties called COMP_MFG and COMP_MFG_PN that it editable at a component level. When we try to add COMP_VALUE it is reported as a reserved name in Cadence but this name is not listed in the properties dialog. Is there a way to turn on the visibility and editablility of this or other hidden reserved Cadence property names? How can I assign a string value to the COMP_VALUE property?

Thanks

Hello,

I have a question I want to create a cover that consists a sparse values, pre-computed (a list or define) for example l = {1; 4; 7; 9; 2048; 700} I'd like to cover that data a (uint(bits:16)) had those values, Any suggestion on how to achieve this, I'd prefer to stay away from macros, and avoid to write a lot of code

struct inst {

  data :uint(bits:16);
  opcode :uint(bits:16);
  !valid_data : list of uint(bits:16) = {0; 12; 10; 700; 890; 293;};
  event data_e;
  event opcode_e;

  cover data_e is {
     item data using radix = HEX, ranges = {
     //I dont want to write all of this
     range([0], "My range1");
     range([10], "My range2");
     //... many values in between
    range([700], "My rangen");
    };

    item opcode;

   cross data, opcode;
};

post_generate() is also {
    emit data_e;
};
};

Hi,

I am trying to characterize a D flip-flop for low voltage operation (0.6V) using Cadence Liberate (V16). This is a positive edge triggered D flip flop based on true-single-phase clocking scheme. After the characterization, the measurements reported for hold constraint arcs seem to deviate significantly from its (spectre) spice simulation.

The constraint and the power settings to the liberate are as follows : 

# -------------------------------------------- Timing Constraints --------------------------------------------------------------------------------
### Input waveform ###
set_var predriver_waveform 2;# 2=use pre-driver waveform
### Capacitance ###
set_var min_capacitance_for_outputs 1;# write min_capacitance attribute for output pins
### Timing ###
set_var force_condition 4
### Constraint ###
set_var constraint_info 2
#set_var constraint_search_time_abstol 1e-12 ;# 1ps resolution for bisection search
set_var nochange_mode 1 ;# enable nochange_* constraint characterization
### min_pulse_width ###
set_var conditional_mpw 0
set_var constraint_combinational 2

#---------------------------------------------- CCS Settings ----------------------------------------------------------------------------------------
set_var ccsn_include_passgate_attr 1
set_var ccsn_model_related_node_attr 1
set_var write_library_is_unbuffered 1

set_var ccsp_min_pts 15 ;# CCSP accuracy
set_var ccsp_rel_tol 0.01 ;# CCSP accuracy
set_var ccsp_table_reduction 0 ;# CCSP accuracy
set_var ccsp_tail_tol 0.02 ;# CCSP accuracy
set_var ccsp_related_pin_mode 2 ;# use 3 for multiple input switching scnarios and Voltus only libraries

#----------------------------------------------- Power ---------------------------------------------------------------------------------------------------
### Leakage ###
set_var max_leakage_vector [expr 2**10]
set_var leakage_float_internal_supply 0 ;# get worst case leakage for power switch cells when off
set_var reset_negative_leakage_power 1 ;# convert negative leakage current to 0

### Power ###
set_var voltage_map 1 ;# create pg_pin groups, related_power_pin / related_ground_pin
set_var pin_based_power 0 ;# 0=based on VDD only; 1=power based on VDD and VSS (default);
set_var power_combinational_include_output 0 ;# do not include output pins in when conditions for combinational cells

set_var force_default_group 1
set_default_group -criteria {power avg} ;# use average for default power group

#set_var power_subtract_leakage 4 ;# use 4 for cells with exhaustive leakage states.
set_var subtract_hidden_power 2 ;# 1=subtract hidden power for all cells
set_var subtract_hidden_power_use_default 3 ;# 3=subtract hidden power from matched when condition then default group
set_var power_multi_output_binning_mode 1 ;# binning for multi-output cell considered for both timing and power arcs
set_var power_minimize_switching 1
set_var max_hidden_vector [expr 2**10]
#--------------------------------------------------------------------------------------------------------------------------------------------------------------

I specifically used set_var constraint_combinational 2 in the settings, in case the Bisection pass/fail mode fails to capture the constraints. In my spice simulation, the hold_rise (D=1, CLK=R, Q=R) arc at-least requires ~250 ps for minimum CLK/D slew combination (for the  by default smallest capacitive load as per Liberate)  while Liberate reports only ~30 ps. The define_cell template to this flip flop is pretty generic, which does not have any user specified arcs. So which settings most likely affecting the constraint measurements in Liberate and how can I debug this issue ?

Thanks

Anuradha

Hello,

I am using Virtuoso 6.1.7.

I am performing the parasitic extraction of a MOM cap array of 32 caps. I use Quantus QRC and I enable field solver. I select “QRCFS” for field solver type and “High” for field solver accuracy. The unit MOM cap is horizontally and vertically symmetric. The array looks like the sketch below and there are no other structures except the unit caps:

Rationally speaking, the capacitance values of the unit caps should be symmetric with respect to a vertical symmetry axis that is between cap16 and cap17 (shown with dashed red line). For example,

the capacitance of cap1 should be equal to the capacitance of cap32

the capacitance of cap2 should be equal to the capacitance of cap31

etc. as there are no other structures around the caps that might create some asymmetry.

Nevertheless, what I observe is the following after the parasitic extraction:

As it can be seen, the result is not symmetric contrary to what is expected. I should also add that I do not observe this when I perform parasitic extraction with no filed solver.

Why do I get this result? Is it an artifact resulting from the field solver tool (my conclusion was yes but still it must be verified)? If not, how can something like this happen?

Many thanks in advance.

Best regards,

Can

Iowa economic development officials are tentatively endorsing a tax credit for battery storage to complement the state’s wind and solar generation.

Digitalisation is one of the biggest enablers of the global transition to clean energy. From intelligent asset management, to Artificial Intelligence and the Internet of Things. Find out how digitalisation is transforming the management, operation and maintenance of renewable energy assets, and driving a more efficient renewable world.

Minnesota’s largest utility wants to change how the state calculates its trailblazing “value of solar” rate as it faces a potential spike in payments to community solar operators.

Iowa economic development officials are tentatively endorsing a tax credit for battery storage to complement the state’s wind and solar generation.

Iowa economic development officials are tentatively endorsing a tax credit for battery storage to complement the state’s wind and solar generation.

Presentation by Chrys Shea of Christopher Associates.

Iowa economic development officials are tentatively endorsing a tax credit for battery storage to complement the state’s wind and solar generation.

The Community Right to Bid has now been in place for half a decade and whilst its impact has perhaps not been as significant as first thought it has undoubtedly had an impact on assets linked to higher education institutions such as playing fields, ...

In this session we look at high value/reputationally sensitive disputes in the education sector. Running a university or Higher Education Institution is always a complicated business – and never more so than now. The sector is facing a time of unp...

The VAT tribunal has decided that the sale of a 'future property rental business' qualified as a transfer of a going concern. If the sale of a property rental business satisfies the conditions that apply to sales of businesses as going concerns, th...

The 'option to tax', or 'election to waive exemption' is a facility that allows property owners to charge VAT on sales and lettings, rather than exempting them. This means that they can recover VAT they incur on construction and other costs. Various...

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On 1 May, the FCA issued two sets of draft guidance which will be important reading for all firms involved in insurance arrangements and particularly insurers, intermediaries and premium finance lenders. As it considers that the delay involved in co...