RBI action supports rupee amid surging crude oil prices, volatile geopolitics

At the interbank foreign exchange market, the local unit opened at 83.92 and finally settled for the day at 83.96 (provisional), higher by 1 paisa over its previous close of 83.97 against the dollar

Rupee buoyed by weak crude oil prices, RBI intervention

Meanwhile, the dollar index was trading 0.13 per cent lower at 103.73

Thanks to higher participation from retail investors, offer subscribed 0.7 times so far

It was a Catalan opening wherein Gukesh got the complications running in his favour in the later stages of the middle game after grabbing a pawn

The domain was previously owned by Dharmesh Shah, the co-founder and CTO of HubSpot who bought it last year for $15.5 million

Rapid improvements in the stability and efficiency of perovskite-silicon tandem cells are raising commercial hopes

Additive facilitates numerous pharmaceutically relevant reactions through unknown mechanism

The bulk of the recent drop in Reliance’s shares follows disappointing results last month

Sector performance was varied, with IT stocks gaining momentum while realty and energy sectors faced pressure

Sensex, Nifty updates on November 11, 2024: Benchmark stock indices Sensex and Nifty closed flat in highly volatile trade on Monday as continuous FII selling, disappointing quarterly earnings and weak trends from Asian markets dented investor sentiment. After gyrating between highs and lows, benchmark Sensex eked out gains of 9.83 points or 0.01 per cent to settle at 79,496.15. The barometer gyrated 1,100.8 points between the day’s high of 80,102.14 and a low of 79,001.34. The NSE Nifty dipped marginally by 6.90 points or 0.03 per cent to 24,141.30. From the 30-share Sensex pack, Asian Paints tumbled over 8 per cent after the company on Saturday reported a 43.71 per cent decline in consolidated net profit to Rs 693.66 crore for the September quarter, impacted by soft-demand conditions, material price inflation and a decline in decorative and coatings business in the domestic market. Tata Steel, Bajaj Finance, Mahindra & Mahindra, JSW Steel, NTPC, Adani Ports, Bajaj Finserv and Larsen & Toubro were also among the laggards. However, Power Grid, HCL Technologies, Infosys, Tech Mahindra, Tata Consultancy Services and ICICI Bank were among the gainers.

Asian Paints Stock, Asian Paints Share Price Updates November 11, 2024: Shares of Asian Paints in focus 

The NSE Nifty dipped marginally by 6.90 points or 0.03 per cent to 24,141.30

Hindalco, ONGC, Ramco Cements & Ambuja Cements Share Price Highlights; Sagility IPO Listing November 12, 2024

“We suffered from catastrophic success so just trying to play the same way... is a real challenge,” said Chennai Super Kings coach Stephen Fleming after the team’s final IPL 2022 match against Rajasthan Royals

Investors' wealth eroded by a whopping Rs 7.15 lakh crore during the morning trade on Friday as equity markets tumbled, driven by sharp fall in IndusInd Bank shares and unabated foreign fund outflows.

Tata Steel, Bajaj Finance, Mahindra and Mahindra, JSW Steel, NTPC, Adani Ports, Bajaj Finserv and Larsen and Toubro were also among the laggards. However, Power Grid, HCL Technologies, Infosys, Tech Mahindra, Tata Consultancy Services and ICICI Bank were among the gainers.

IMAGES from the EPL matches played on Saturday.

With the close of the latest fund, Quona Capital’s AUM currently stands at $363 million.

The post Quona Capital closes second fund at $203m to invest in fintech firms appeared first on DealStreetAsia.

Trump administration under pressure to cover healthcare costs as unemployment rises to postwar high

The new plans - which are already progressing in London and Manchester -  will involve blocking off the areas outside schools with cones and barriers.

1. Astronomers Identify Closest Black Hole to Earth  VOA Learning English
2. Astronomers find closest black hole to Earth yet to be discovered  9News
3. New black hole discovered - and it's the closest to Earth ever found, say scientists  Mirror Online
4. View Full coverage on Google News

The SLGA retail store and the private off sale in La Loche are closed for two weeks, the province announced.

Justin Gaethje produces the best performance of his career to finish Tony Ferguson and win the UFC interim lightweight title at UFC 249.

Two more businesses operating in Calgary have been shut down by health officials for violating the province's rules regarding COVID-19.

French tennis chief Bernard Guidicelli admitted that Roland Garros could be staged behind closed doors.

A department store that served Vancouver's Gastown and Downtown Eastside neighbourhoods for decades is closing, along with four other Army and Navy locations, because of the COVID-19 pandemic.

Representative Michael McCaul, who has harshly criticized China in his position as the ranking member on the House Foreign Affairs Committee, disclosed that his family owns stock in a Chinese tech company he described as a threat to national security.An April 20 periodic transaction report showed that McCaul disclosed a February purchase of between $50,000 and $100,000 in shares of the Chinese firm Tencent Holdings, Politico reported.In November, several months before the shares were purchased, the Texas congressman said that Tencent Holdings is among the "Chinese companies that threaten America’s economic and national security."The tech conglomerate is "heavily involved" in the "social credit system, a dystopian system China has implemented to score its citizens’ behavior," McCaul said at the time, as well as an "integral part" of the Chinese Communist Party’s industrial policies and "one of four national champions for artificial intelligence."McCaul's lawyer, Elliot Berke, said that the shares are not owned personally by McCaul but by his wife, and the decision to invest in Tencent was made by a third party.“Congressman McCaul did not purchase any shares in China’s Tencent Holdings or any other Chinese company,” the attorney said. “Congressman McCaul’s wife has assets she solely owns and a third party manager made the purchase without her direction.”Rachel Walker, a spokeswoman for McCaul, emphasized that the revelation of the Tencent shares “highlights that many Americans unwittingly invest their money in Chinese owned companies."Federal employees are often unaware they own such investments because the federal government’s thrift savings plan program creates portfolios that include Tencent and other Chinese companies, Walker said. McCaul has argued that such retirement investment plans should not invest American dollars in such "shady" Chinese companies, often without the knowledge of the investor."Congressman McCaul has been a fierce critic of the brutal behavior of the Chinese Communist Party and will continue to fight to hold them accountable as the Chair of the China Task Force," Walker said. "This should be a wake-up call to us all that the CCP’s involvement in the U.S. economy is far more reaching than many Americans realize and that we need to change the way we do business with China, including our investments."Tencent owns the Chinese social media platform WeChat, which has more than one billion users and is suspected of monitoring the activities of users both inside and outside of China. Tencent is also associated with Chinese tech firm Huawei, which U.S. officials said can secretly access American cellular phone networks, giving it access to sensitive information.McCaul has taken a leading role in criticizing China's handling of the coronavirus pandemic as well, accusing Beijing of launching perhaps the "worst cover-up in human history."He was tapped on Thursday by House Minority Leader Kevin McCarthy as chairman of the China Task Force, the aim of which is to develop "legislative solutions to address the Chinese Communist Party’s malign global agenda."The task force will "develop new and enduring policy solutions that, among others, enhance our economic strength and create jobs, protect our national security, rethink our supply chains and grow our competitive edge in technology," McCaul said in a statement on his appointment.

In a tweet Saturday morning, Tesla's chief executive said it would file a lawsuit against county officials over not being able to run its factory.

Lethal infections by strains of the highly-pathogenic avian influenza virus (HPAIV) H5N1 pose serious threats to both the poultry industry and public health worldwide. A lack of confirmed HPAIV epitopes recognized by cytotoxic T lymphocytes (CTLs) has hindered the utilization of CD8+ T-cell–mediated immunity and has precluded the development of effectively diversified epitope-based vaccination approaches. In particular, an HPAIV H5N1 CTL-recognized epitope based on the peptide MHC-I–β2m (pMHC-I) complex has not yet been designed. Here, screening a collection of selected peptides of several HPAIV strains against a specific pathogen-free pMHC-I (pBF2*1501), we identified a highly-conserved HPAIV H5N1 CTL epitope, named HPAIV–PA123–130. We determined the structure of the BF2*1501–PA123–130 complex at 2.1 Å resolution to elucidate the molecular mechanisms of a preferential presentation of the highly-conserved PA123–130 epitope in the chicken B15 lineage. Conformational characteristics of the PA123–130 epitope with a protruding Tyr-7 residue indicated that this epitope has great potential to be recognized by specific TCRs. Moreover, significantly increased numbers of CD8+ T cells specific for the HPAIV–PA123–130 epitope in peptide-immunized chickens indicated that a repertoire of CD8+ T cells can specifically respond to this epitope. We anticipate that the identification and structural characterization of the PA123–130 epitope reported here could enable further studies of CTL immunity against HPAIV H5N1. Such studies may aid in the development of vaccine development strategies using well-conserved internal viral antigens in chickens.

Bacterial biofilms are cellular communities that produce an adherent matrix. Exopolysaccharides are key structural components of this matrix and are required for the assembly and architecture of biofilms produced by a wide variety of microorganisms. The human bacterial pathogens Escherichia coli and Salmonella enterica produce a biofilm matrix composed primarily of the exopolysaccharide phosphoethanolamine (pEtN) cellulose. Once thought to be composed of only underivatized cellulose, the pEtN modification present in these matrices has been implicated in the overall architecture and integrity of the biofilm. However, an understanding of the mechanism underlying pEtN derivatization of the cellulose exopolysaccharide remains elusive. The bacterial cellulose synthase subunit G (BcsG) is a predicted inner membrane–localized metalloenzyme that has been proposed to catalyze the transfer of the pEtN group from membrane phospholipids to cellulose. Here we present evidence that the C-terminal domain of BcsG from E. coli (EcBcsGΔN) functions as a phosphoethanolamine transferase in vitro with substrate preference for cellulosic materials. Structural characterization of EcBcsGΔN revealed that it belongs to the alkaline phosphatase superfamily, contains a Zn2+ ion at its active center, and is structurally similar to characterized enzymes that confer colistin resistance in Gram-negative bacteria. Informed by our structural studies, we present a functional complementation experiment in E. coli AR3110, indicating that the activity of the BcsG C-terminal domain is essential for integrity of the pellicular biofilm. Furthermore, our results established a similar but distinct active-site architecture and catalytic mechanism shared between BcsG and the colistin resistance enzymes.

Uber lost US$2.9 billion in the first quarter as its overseas investments were hammered by the coronavirus pandemic, but the company is looking to its growing food delivery business and aggressive cost-cutting to ease the pain. The ride-hailing...

(CMC): Trinidad and Tobago says its borders are to remain closed until June, even as it embarks on softening restrictions to re energise the economy, which had been halted by COVID-19.   Prime Minister Dr Keith Rowley said the...

A Calgary coffee shop must close public access to its patio and dine-in services, Alberta Health Services says.

The family owned Army & Navy department store chain is closing after more than a century in business.

A new partner ministry broadcasting Urdu-speaking programmes to 360+ million who speak it, is giving them hope for eternity.

MSPS were really quite excited last week to be taking part in a largely symbolic vote with an entirely predictable outcome.