hose Obituary: Brian Dennehy, imposing actor whose range spanned grizzled cops and Willy Loman By www.heraldscotland.com Published On :: Thu, 30 Apr 2020 05:03:51 +0100 Born: July 9, 1938; Full Article
hose Obituary: Alan Gray: A man whose veins ran with whisky By www.heraldscotland.com Published On :: Thu, 07 May 2020 05:04:02 +0100 Alan Gray – An Appreciation Full Article
hose Cord Cutting Is Great, Except for Those Live Events By www.pcmag.com Published On :: The more popular the stream, the worse it looks. There is a technology out there that would work, but its association with piracy has companies afraid of using it. Full Article
hose New Monument Honors Delaware’s WWI Veterans and Those Who Served on the Home Front By news.delaware.gov Published On :: Mon, 06 Nov 2017 16:37:31 +0000 The Delaware General Assembly, the Delaware Commission of Veterans Affairs and the Delaware Heritage Commission unveiled a new monument in honor of those Delawareans who served their state and the nation in World War I. Full Article Department of State Governor John Carney Office of the Governor Office of Veterans Services Commission of Veterans Affairs Delaware General Assembly Veterans World War I
hose Indian Embassy In US Contacts Those Who Wish To Travel Back Home By www.ndtv.com Published On :: Thu, 30 Apr 2020 10:10:24 +0530 The Indian Embassy here has started to contact the Indian nationals who wish to return home once the international travel lockdown due to the coronavirus pandemic is lifted. Full Article Indians Abroad
hose Delaware thoroughbred officials chosen to lead Organization of Racing Investigators By news.delaware.gov Published On :: Wed, 18 Mar 2015 13:19:38 +0000 Two Delaware racing officials have been named chairman and secretary of the Organization of Racing Investigators, which represents racetracks, regulatory agencies and law enforcement involved in upholding the integrity of horse racing. Full Article Department of Agriculture News equine
hose Delaware One of Eight States Chosen by the National Governors Association to Participate in Health Care Data Initiative By news.delaware.gov Published On :: Mon, 25 Jun 2018 15:09:54 +0000 WILMINGTON, Del. – In support of a movement to transform how health care is delivered and paid for in the state, Delaware was one of eight states chosen to participate in a National Governors Association initiative to harness data systems to inform health policymaking. Joining Arkansas, Colorado, Indiana, Iowa, Minnesota, Vermont and Washington, Delaware’s team […] Full Article Delaware Health and Social Services Governor John Carney News Office of the Governor data Governor Carney Health care medicaid medicare
hose Substance Abuse and Mental Health, Partners Open Bridge Clinic for Those Impacted by Mental Health, Addiction Issues By news.delaware.gov Published On :: Tue, 26 Mar 2019 18:28:39 +0000 NEW CASTLE (March 26, 2019) – As a new support for individuals and families impacted by the effects of mental health and substance use disorders, the Division of Substance Abuse and Mental Health (DSAMH) and its partners have opened the Bridge Clinic near New Castle to provide screening and referrals to treatment, as well as […] Full Article Delaware Health and Social Services News Addiction addictiontreatment substance use
hose Dementia Friendly Delaware to Support Those with Dementia, Their Families By news.delaware.gov Published On :: Mon, 29 Apr 2019 21:25:31 +0000 Lt. Governor Bethany Hall-Long and the Delaware Department of Health and Social Services’ Division of Services for Aging and Adults with Physical Disabilities (DSAAPD) are hosting an event on Tuesday, April 30, in Dover to show what Dementia Friendly Delaware can offer for Delawareans living with dementia and their families. Dementia Friendly Delaware (DFD) is […] Full Article Delaware Health and Social Services Lt. Governor Bethany Hall-Long News Office of the Lieutenant Governor Alzheimer's disease caregivers dementia Dementia Friendly Delaware Division of Services for Aging and Adults with Physical Disabilities
hose Patients of Sussex County Doctor Whose Medical License, Controlled Substance Registration Revoked Getting Resources By news.delaware.gov Published On :: Thu, 09 May 2019 22:10:00 +0000 DOVER (May 9, 2019) – On May 8, 2019, the medical license and controlled substance registrations of Nihar B. Gala, MD, were permanently revoked by the Delaware Board of Medical Licensure and Discipline. The revocation was a result of allegations of unprofessional conduct related to the prescription of opioids to a patient at high risk […] Full Article Delaware Health and Social Services Department of State Division of Public Health News Sussex County controlled substance registration Dr. Nihar B. Gala DSAMH HelpIsHereDE.com medical license Mobile Crisis prescriber revoked
hose Patients of NCCo Doctor Whose Medical License, Controlled Substance Registration Suspended Urged to Seek Ongoing Care By news.delaware.gov Published On :: Thu, 01 Aug 2019 15:16:42 +0000 DOVER (Aug. 1, 2019) – On July 30, 2019, the medical license and controlled substance registration of Damon Cary, MD, were suspended temporarily by the Delaware Board of Medical Licensure and Discipline. The suspension was the result of a request made by the Delaware Attorney General’s Office following investigations into the prescribing and treatment practices […] Full Article Delaware Health and Social Services Department of State Division of Public Health benziodiazepine withdrawal Damon Cary HelpIsHereDE.com medical license medical practice opioid withdrawal patients
hose Karnataka Awaits Consent Of 6 States To Operate Trains For Those Stranded By www.ndtv.com Published On :: Fri, 08 May 2020 22:28:52 +0530 The Karnataka government is awaiting the approval of 6 out of the 11 states, that it had written for consent, to operate trains for the movement of stranded people. Full Article Karnataka
hose 14-Day Mandatory Quarantine For Those From Red Zone: Pinarayi Vijayan By www.ndtv.com Published On :: Sat, 09 May 2020 06:24:29 +0530 Kerala Chief Minister Pinarayi Vijayan on Friday said that those coming from red zones will have to be in mandatory institutional quarantine for 14 days and would be moved to the quarantine facility... Full Article All India
hose Your Money: Investment tips for those opting for new tax regime By www.financialexpress.com Published On :: 2020-04-21T00:30:00+05:30 For example, PPF offers you returns of 7.1% per annum completely tax-free whereas an 8% FD may offer you only 5.6% if you’re in the 30% slab. Full Article Income Tax Money
hose Aarogya Setu IVRS facility launched for those without smartphones; check how to use Coronavirus tracker app By www.financialexpress.com Published On :: 2020-05-07T00:44:00+05:30 Coronavirus in India: Close to 9 crore users have downloaded the Aarogya Setu mobile application so far, a ministry official said. Full Article Health Lifestyle
hose Nurse is the chosen superhero in new Banksy artwork By www.dailystar.com.lb Published On :: 2020-05-07T11:10:00.0000000 'Thanks for all you’re doing,' the artist said in a note for hospital workers. 'I hope this brightens the place up a bit, even if it’s only black and white.' Full Article Culture
hose CAA protests: Those born here before 1987 are Indians, clarifies government By www.financialexpress.com Published On :: 2019-12-21T00:27:00+05:30 A top government official said according to the 2004 amendments of the Citizenship Act, if one parent is an Indian and neither is an illegal immigrant, a person is considered an Indian citizen. Full Article India
hose Coronavirus outbreak: All national camps, except those preparing for Olympics, postponed due to COVID-19, says Kiren Rijiju By www.financialexpress.com Published On :: 2020-03-17T15:50:00+05:30 In India, the shooting World Cup and Indian Open Golf has been postponed so far, while badminton's India Open was also deferred after the Badminton World Federation (BWF) suspended all World Tour and sanctioned events. Full Article Sports
hose Coronavirus outbreak: Quarantine measures in Delhi tightened for those coming from abroad By www.financialexpress.com Published On :: 2020-03-17T14:43:00+05:30 According to the new guidelines put in place by the Delhi government, all passengers travelling back to India from these Coronavirus-hit countries will be sent to quarantine centres straightway after their arrival at the Delhi airport. Full Article Lifestyle Travel & Tourism
hose Covid-19: Armed Forces set up quarantine facilities for those returning from overseas By www.financialexpress.com Published On :: 2020-05-09T13:39:00+05:30 The Indian Navy has also set up a facility at Visakhapatnam, which too can take in 200 people with all the facilities available inside. Full Article Defence
hose Only those with severe symptoms to be tested before discharge: New COVID-19 policy - The News Minute By news.google.com Published On :: Sat, 09 May 2020 10:44:07 GMT Only those with severe symptoms to be tested before discharge: New COVID-19 policy The News MinuteCoronavirus India lockdown Day 46 live updates | Testing capacity for COVID-19 scaled up to 95,000 per day: Harsh Vardhan The Hindu'Have prepared country for worst situation': Union Health Minister Harsh Vardhan on coronavirus pandemic Times NowCoronavirus India Updates, May 09: Cases near 60,000 mark; testing capacity scaled up to 95,000 per day The Indian ExpressFocus On Effective Surveillance Of COVID-19, Contact Tracing: Centre To 3 Southern States FUTURE TVView Full coverage on Google News Full Article
hose What are those?!?! The Bottom 10 sneakers in NBA history By www.espn.com Published On :: Wed, 6 May 2020 07:41:40 EST In fact, they're the worst of the worst. Full Article
hose Senior Night: Celebrating NCAA athletes whose seasons were cut short By www.espn.com Published On :: Fri, 8 May 2020 08:40:34 EST The entire sports world was put on hold amid the coronavirus pandemic, leaving college seniors to ask, "What if?" Full Article
hose 7 Habits of Highly Successful S-Parameters: How to Simulate Those Pesky S-Parameters in a Time Domain Simulator By feedproxy.google.com Published On :: Tue, 16 May 2017 20:11:02 GMT Hello Spectre Users, Simulating S-parameters in a time domain (transient, periodic steady state) simulator has been and continues to be a challenge for many analog and RF designers. I'm often asked: What is required in order to achieve accurate...(read more) Full Article S-parameter Spectre RF Spectre International Microwave Symposium
hose Link to: 7 Habits of Highly Successful S-Parameters: How to Simulate Those Pesky S-Parameters in a Time Domain Simulator By feedproxy.google.com Published On :: Thu, 06 Jul 2017 22:18:34 GMT Hi All, If you were unable to attend IMS 2017 in June 2017, the IMS MicroApp “7 Habits of Highly Successful S-Parameters” is on our Cadence website. On Cadence Online Support , the in-depth AppNote is here: 20466646 . Best regards, Tawna...(read more) Full Article nport analog/RF APS S-parameter Virtuoso Spectre Spectre RF broadband SPICE nport settings RF spectre spectreRF spectreRF s parameter simulation
hose 1G Mobile: AMPS, TOPS, C-450, Radiocom 2000, and All Those Japanese Ones By community.cadence.com Published On :: Thu, 30 Apr 2020 12:00:00 GMT You can't read anything about technology these days without reading about 5G. But before there was 5G, there was 4G. And before that 3G, 2G, and 1G. A 0G even. For the next few Thursdays,... [[ Click on the title to access the full blog on the Cadence Community site. ]] Full Article
hose Those Affected By The Yahoo! Hacks May Only Get 60 Cents By packetstormsecurity.com Published On :: Fri, 07 Feb 2020 13:39:15 GMT Full Article headline hacker privacy data loss yahoo
hose Mozilla's Firefox 70 Is Out: Privacy Reports Reveal Whose Cookies Are Tracking You By packetstormsecurity.com Published On :: Wed, 23 Oct 2019 18:24:33 GMT Full Article headline privacy spyware mozilla
hose Chosen for Glory (2 Thessalonians 2:13-14) By feeds.gty.org Published On :: Sun, 02 Jun 2019 00:00:00 Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church. Full Article 2 Thessalonians
hose Public procurement: New case highlights pitfalls for those challenging award decisions By www.eversheds.com Published On :: 2017-08-04 On 21 July the Technology and Construction Court handed down judgment in relation to two applications made in the case of Perinatal Institute v Healthcare Quality Improvement Partnership. This interesting judgment highlights two potential pitfalls f... Full Article
hose City of Joburg says it won't cut services of those unable to pay during lockdown By www.iol.co.za Published On :: Fri, 08 May 2020 07:45:00 GMT The City says it will revise its budget to cater especially for Covid-19 repercussions before the end of the month as the number of ratepayers and residents paying their municipal bills continues to drop. Full Article
hose Whose Fault Is Our Temptation? A By feeds.gty.org Published On :: Wed, 19 Feb 2020 00:00:00 PST Full Article
hose Whose Fault Is Our Temptation? B By feeds.gty.org Published On :: Thu, 20 Feb 2020 00:00:00 PST Full Article
hose Whose Fault Is Our Temptation? By feeds.gty.org Published On :: Wed, 22 Apr 2020 00:00:00 PST Full Article
hose UK expected to require 14-day quarantine for those entering country By article.wn.com Published On :: Sat, 09 May 2020 14:04 GMT The U.K. is expected to require incoming airline passengers to self-quarantine for 14 days upon arrival in the country due to concerns about the coronavirus, according to local reports. The only passengers who are exempt from the new protocol, expected to... Full Article
hose Cayetano warns of ‘reckoning’ for those responsible for ABS-CBN franchise ‘mess’ By www.manilatimes.net Published On :: Fri, 08 May 2020 06:30:53 +0000 SPEAKER Alan Peter Cayetano breaks his silence on the closure of media giant ABS-CBN Corp. after a cease and desist order was issued by the National Telecommunications Commission (NTC) and warned of “reckoning” for those responsible for the “mess”. “Last Tuesday we were all ambushed by the NTC,” Cayetano said in a statement posted on […] Full Article Latest Stories Today's Breaking News ABS-CBN franchise Cayetano
hose On Whose Door Is Christ Knocking? By feeds.gty.org Published On :: Wed, 17 Jul 2019 00:00:00 PST In the lead-up to the Truth Matters conference in October, we will be focusing our attention on the sufficiency, authority, and clarity of Scripture. Of our previous blog series, none better embodies that emphasis than Frequently Abused Verses. The following entry from that series originally appeared on October 5, 2015. -ed. Is it really “abuse” if a verse is used inaccurately to make an important point? The short answer is, “Yes.” We should not be so careless and cavalier with Scripture, or think so highly of ourselves, that we can impose new meaning—even if it is valid—on the inerrant, sufficient Word of God. If the point is worth making, it’s worth making from the appropriate text. Which brings us to the verse before us today: Revelation 3:20 is certainly one of the most familiar and frequently-quoted verses in the church. It’s a particular favorite for evangelists, camp preachers, and anyone else who wants to lend some urgency to the call of God on a sinner’s life “Behold, I stand at the door and knock; if anyone hears My voice and opens the door, I will come in to him and will dine with him, and he with Me” (Revelation 3:20). In the hands of many preachers and evangelists, the verse paints an attractive, compelling picture of Christ’s pursuit of the sinner, and highlights the need for an immediate response. But is that an accurate interpretation of the verse—is Christ truly at the doorstep of each sinner’s heart, pleading to come in? And if not, on whose door is the Lord knocking? Let’s tackle those issues one at a time. Is Christ Knocking? We use a lot of clichés as shorthand in the church, and not all of them are helpful or even accurate. For example, many Christians talk about “asking Jesus into your heart.” And while that phrase might have some vaguely biblical underpinnings, it doesn’t shed any light on what it truly means to repent and believe. If anything, it muddles the sinner’s responsibility in salvation; it dulls some of the sharp edges of the gospel. In the same way, the common misapplication of Revelation 3:20 has done more harm than good. Yes, the mental image of Christ knocking on the door of a sinner’s heart is moving. But it’s not accurate—it’s a caricature at best, and it comes at a high theological cost. Put simply, Christ isn’t pleading on every sinner’s spiritual doorstep. Jesus doesn’t need to beg or badger anyone into the kingdom of heaven (John 10:27-28). Salvation isn’t merely a matter of the Lord getting a foot inside the door of your heart—it’s a work of total transformation (Ezekiel 36:26). And most important of all, salvation is not triggered by an act of the sinner’s will—it is God’s intervening work that rescues us from the just penalty of our sin (Ephesians 2:4-9). In fact, the abuse of Revelation 3:20 often goes hand-in-hand with talk of “asking Jesus into your heart” and other man-centered versions of the gospel message. One way to protect yourself and your evangelism from such skewed perspectives is to closely adhere to biblical language when you’re explaining the gospel. And you were dead in your trespasses and sins, in which you formerly walked according to the course of this world, according to the prince of the power of the air, of the spirit that is now working in the sons of disobedience. Among them we too all formerly lived in the lusts of our flesh, indulging the desires of the flesh and of the mind, and were by nature children of wrath, even as the rest. But God, being rich in mercy, because of His great love with which He loved us, even when we were dead in our transgressions, made us alive together with Christ (by grace you have been saved), and raised us up with Him, and seated us with Him in the heavenly places in Christ Jesus, so that in the ages to come He might show the surpassing riches of His grace in kindness toward us in Christ Jesus. For by grace you have been saved through faith; and that not of yourselves, it is the gift of God; not as a result of works, so that no one may boast. (Ephesians 2:1-9, emphasis added) Train yourself to think about the gospel in those terms, and you’ll insulate yourself from the influence of man-centered theology, and the temptation to reinterpret God’s Word. Whose Door? The door in Revelation 3:20 was not a vague spiritual metaphor—it was a specific door. And while Christ wasn’t physically knocking, His words were directed to a specific group of people, and should not be watered down or applied carelessly to just anyone. The context of Revelation 3:20 is Christ’s letter to the church at Laodicea—also known as the lukewarm church. In Revelation 3:14-22, the Lord condemns them for their spiritual self-deception and apathy. Christ says, “I know your deeds, that you are neither cold nor hot; I wish that you were cold or hot” (v. 15). They did not openly reject Christ, but neither did they exhibit any spiritual zeal or authentic love for God or His Word. They professed to know Christ, but He had no place in their assembly. And lost in their self-deception, they risked being spat out of God’s mouth altogether (v. 16). Their only hope was to truly repent (v. 19). In the context of Revelation 3, then, Christ was standing at the door of the Laodicean church, eager to re-enter the congregation through the genuine repentance and salvation of its members. In his commentary on this passage, John MacArthur explains the imagery of verse 20: Though this verse has been used in countless tracts and evangelistic messages to depict Christ’s knocking on the door of the sinner’s heart, it is broader than that. The door on which Christ is knocking is not the door to a single human heart, but to the Laodicean church. Christ was outside this apostate church and wanted to come in—something that could only happen if the people repented. The invitation is, first of all, a personal one, since salvation is individual. But He is knocking on the door of the church, calling the many to saving faith, so that He may enter the church. If one person (anyone) opened the door by repentance and faith, Christ would enter that church through that individual. The picture of Christ outside the Laodicean church seeking entrance strongly implies that, unlike Sardis, there were no believers there at all. Christ’s offer to dine with the repentant church speaks of fellowship, communion, and intimacy. Sharing a meal in ancient times symbolized the union of people in loving fellowship. Believers will dine with Christ at the marriage supper of the Lamb (Revelation 19:9), and in the millennial kingdom (Luke 22:16, 29-30). Dine is from deipneō, which refers to the evening meal, the last meal of the day. The Lord Jesus Christ urged them to repent and have fellowship with Him before the night of judgment fell and it was too late forever. [1] John MacArthur, The MacArthur New Testament Commentary: Revelation 1-11 (Chicago: Moody Press, 1999) 140. What does repentance look like? Far from merely opening the door of your heart to Christ, true repentance reflects the conviction of your sin and the deep desire for righteousness. Here’s how D. Martyn Lloyd-Jones defined this important doctrine: Repentance means that you realize that you are a guilty, vile sinner in the presence of God, that you deserve the wrath and punishment of God, that you are hell-bound. It means that you begin to realize that this thing called sin is in you, that you long to get rid of it, and that you turn your back on it in every shape and form. You renounce the world whatever the cost, the world in its mind and outlook as well as its practice, and you deny yourself, and take up the cross and go after Christ. [2] D. Martyn Lloyd-Jones, Studies in the Sermon on the Mount (Grand Rapids: Eerdmans, 1974) 2:248. The Urgent Call of the Gospel When it comes to applying and interpreting Scripture, the details matter; good intentions are not enough. We bring the authority of Scripture to bear in sinners’ lives only inasmuch as we handle it accurately. We have a responsibility to the Lord, to each other, and to the unsaved world to proclaim the excellence, inerrancy, and sufficiency of the Bible. And we can’t fulfill that responsibility if we’re assigning our own meaning to God’s immutable truth. With that in mind, you may still want to inject some urgency into the call to repent the next time you share the gospel with friends or family. Rather than falling back on a misappropriation of Christ’s words in Revelation, why not make a biblically sound argument? Here are a couple passages that convey the sinner’s urgent spiritual needs. Isaiah preached to the apostate nation of Israel pleading with them to return to the Lord: Seek the Lord while He may be found; call upon Him while He is near. Let the wicked forsake his way and the unrighteous man his thoughts; and let him return to the Lord, and He will have compassion on him, and to our God, for He will abundantly pardon. (Isaiah 55:6-7) And in Acts 17 Paul ended his gospel appeal to a crowd of philosophers with these words: Therefore having overlooked the times of ignorance, God is now declaring to men that all people everywhere should repent, because He has fixed a day in which He will judge the world in righteousness through a Man whom He has appointed, having furnished proof to all men by raising Him from the dead. (Acts 17:30-31) These and other passages (cf. Acts 2:37-40; Hebrews 4:6-7) can be rightly used to urge unbelievers or those lost in self-deception to respond to the gospel by repenting and turning to Christ. What good is our evangelistic zeal if we aren’t biblically sound? Full Article
hose Gov't continues to offer help to those affected by coronavirus By praguemonitor.com Published On :: Prague Daily Monitor The government has already passed several measures which are designed to assist and help people cope with the situation surrounding the current lock-down, school and business closures and other related problems. The government has agreed to compensate employees of closed businesses, which include restaurants, bars, stores and other deemed non-essential operations. The government will compensate 80% of wages for the employees who are affected. read more Full Article
hose Don’t neglect those with underlying illnesses By www.nation.co.ke Published On :: 2020-05-08T20:21:00Z Community health workers can sensitise individuals. Full Article
hose Ken Buck aide among those accused of election fraud, corruption by Weld County GOP chair By www.denverpost.com Published On :: Fri, 08 May 2020 23:38:00 +0000 The Weld County GOP chairman has filed a complaint with the local district attorney and the Secretary of State’s Office accusing an aide to Republican U.S. Rep. Ken Buck and three others of election fraud and corruption. Full Article Colorado Politics National Politics News Politics Colorado Secretary of State's Office Ken Buck politics Weld County Weld County District Attorney
hose Hack Those Headphones: First Developer-Ready Consumer Headphones to Hit TechCrunch Disrupt By news.harman.com Published On :: Thu, 05 May 2016 18:40:00 GMT STAMFORD, CT – May 5, 2016 – Today, HARMAN International Industries, Incorporated (NYSE:HAR), the premier connected technologies company for automotive, consumer and enterprise markets, announced it will showcase the industry’s first developer-ready ... Full Article
hose A British nurse is the chosen superhero in new Banksy artwork By feeds.reuters.com Published On :: Wed, 06 May 2020 20:03:15 -0400 A young boy chooses a nurse as the superhero he wants to play with over Batman and Spiderman in a new artwork by Banksy that encapsulates the gratitude Britons have felt toward the country's National... Full Article lifestyleMolt
hose A British nurse is the chosen superhero in new Banksy artwork By feeds.reuters.com Published On :: Wed, 06 May 2020 20:03:15 -0400 A young boy chooses a nurse as the superhero he wants to play with over Batman and Spiderman in a new artwork by Banksy that encapsulates the gratitude Britons have felt toward the country's National Health Service during the coronavirus crisis. Full Article artsNews
hose MRI May Help Gauge Stroke Risk in Those With Irregular Heartbeat By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: MRI May Help Gauge Stroke Risk in Those With Irregular HeartbeatCategory: Health NewsCreated: 4/27/2015 12:00:00 AMLast Editorial Review: 4/27/2015 12:00:00 AM Full Article
hose ER Practices Key to Helping Those Addicted to Painkillers: Study By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: ER Practices Key to Helping Those Addicted to Painkillers: StudyCategory: Health NewsCreated: 4/28/2015 12:00:00 AMLast Editorial Review: 4/29/2015 12:00:00 AM Full Article
hose Sleep Doesn't Come Easy to Those With Brain Injuries By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Sleep Doesn't Come Easy to Those With Brain InjuriesCategory: Health NewsCreated: 4/27/2016 12:00:00 AMLast Editorial Review: 4/28/2016 12:00:00 AM Full Article
hose COMMENTARY: COVID-19: Be Wary of Those Racing to Fill the Therapeutic Void By www.webmd.com Published On :: Fri, 08 May 2020 12:57:23 EST Dr Aaron Holley warns against following 'false prophets' as we confront treatment decisions for patients with COVID-19. Full Article
hose Aftermath of Seizures Troubling for Those With Epilepsy By www.medicinenet.com Published On :: Mon, 20 Apr 2020 00:00:00 PDT Title: Aftermath of Seizures Troubling for Those With EpilepsyCategory: Health NewsCreated: 4/17/2020 12:00:00 AMLast Editorial Review: 4/20/2020 12:00:00 AM Full Article
hose Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial Comparing the Reactogenicity and Immunogenicity of a Single Standard Dose to Those of a High Dose of CVD 103-HgR Live Attenuated Oral Cholera Vaccine, with Shanchol Inactivated Oral Vaccine as an By cvi.asm.org Published On :: 2017-12-05T08:00:30-08:00 Reactive immunization with a single-dose cholera vaccine that could rapidly (within days) protect immunologically naive individuals during virgin soil epidemics, when cholera reaches immunologically naive populations that have not experienced cholera for decades, would facilitate cholera control. One dose of attenuated Vibrio cholerae O1 classical Inaba vaccine CVD 103-HgR (Vaxchora) containing ≥2 x 108 CFU induces vibriocidal antibody seroconversion (a correlate of protection) in >90% of U.S. adults. A previous CVD 103-HgR commercial formulation required ≥2 x 109 CFU to elicit high levels of seroconversion in populations in developing countries. We compared the vibriocidal responses of Malians (individuals 18 to 45 years old) randomized to ingest a single ≥2 x 108-CFU standard dose (n = 50) or a ≥2 x 109-CFU high dose (n = 50) of PaxVax CVD 103-HgR with buffer or two doses (n = 50) of Shanchol inactivated cholera vaccine (the immunologic comparator). To maintain blinding, participants were dosed twice 2 weeks apart; CVD 103-HgR recipients ingested placebo 2 weeks before or after ingesting vaccine. Seroconversion (a ≥4-fold vibriocidal titer rise) between the baseline and 14 days after CVD 103-HgR ingestion and following the first and second doses of Shanchol were the main outcomes measured. By day 14 postvaccination, the rates of seroconversion after ingestion of a single standard dose and a high dose of CVD 103-HgR were 71.7% (33/46 participants) and 83.3% (40/48 participants), respectively. The rate of seroconversion following the first dose of Shanchol, 56.0% (28/50 participants), was significantly lower than that following the high dose of CVD 103-HgR (P = 0.003). The vibriocidal geometric mean titer (GMT) of the high dose of CVD 103-HgR exceeded the GMT of the standard dose at day 14 (214 versus 95, P = 0.045) and was ~2-fold higher than the GMT on day 7 and day 14 following the first Shanchol dose (P > 0.05). High-dose CVD 103-HgR is recommended for accelerated evaluation in developing countries to assess its efficacy and practicality in field situations. (This study has been registered at ClinicalTrials.gov under registration no. NCT02145377.) Full Article
hose Disease progression in myeloproliferative neoplasms: comparing patients in accelerated phase with those in chronic phase with increased blasts (<10%) or with other types of disease progression By www.haematologica.org Published On :: 2020-05-01T00:05:42-07:00 Full Article