e v The Vitamin Shoppe fitfactor Weight Management System By www.preparedfoods.com Published On :: Wed, 04 Mar 2020 00:00:00 -0500 The fitfactor Weight Management System™ includes protein shakes, bars, and weight management supplements, combined with online nutrition coaching and community. Full Article
e v New, Established Sources are Pushing Fiber Back into the Vanguard By www.preparedfoods.com Published On :: Mon, 27 Sep 2021 00:00:00 -0400 Americans still are not meeting the recommended intake levels for dietary fiber, a nutritional failure that can lead to the development of a number of health issues down the road. The shortfall is so critical that the new “Dietary Guidelines for Americans 2020-2025” has designated dietary fiber as “a dietary component of public health concern.” Full Article
e v The Value of Premixes in Food and Beverage Product Development By www.preparedfoods.com Published On :: Mon, 19 Dec 2022 05:00:00 -0500 Premixes range from the mandated vitamins and minerals for addressing nutrient shortfalls to trendy ingredients like turmeric, ginger, activated charcoal, collagen, and botanical bioactives that consumers believe are healthier for them. Full Article
e v Soylent High Protein Shake Vanilla By www.preparedfoods.com Published On :: Wed, 30 Aug 2023 08:00:00 -0400 Soylent's Complete Protein Shakes are made with 30g of complete plant protein, 28 immune supporting vitamins & minerals, zero sugar, 1,000mg Omega-3, 250 calories of slow-burning carbs, and 60% of the daily recommended value of protein. Full Article
e v Garden of Life Vitamin Code Gummies By www.preparedfoods.com Published On :: Wed, 08 Nov 2023 05:15:00 -0500 Garden of Life®, the carbon-neutral company operating in science-based formulas made from clean, traceable, non-GMO ingredients, introduced a new gummy extension to its popular Vitamin Code line, with seven products formulated to fit a variety of needs. Full Article
e v Vertical Form/Fill/Seal Machine for Large Volume Filling By www.foodengineeringmag.com Published On :: Thu, 15 Feb 2024 12:06:42 -0500 The eight-lane machine provides auger filling of 40 grams of powder at 75 cycles per minute. Full Article
e v The Vinyl Institute Affirms the Safety of PVC Products By www.floortrendsmag.com Published On :: Wed, 03 Apr 2024 15:00:00 -0400 Ned Monroe, president and CEO of the Vinyl Institute, offers insight into the U.S. Environmental Protection Agency (EPA) announcement that vinyl chloride will be one of the next five chemicals selected for prioritization under the Toxic Substances Control Act. Full Article
e v Versatrim Delivers Aid to Hurricane Helene Victims in North Carolina By www.floortrendsmag.com Published On :: Thu, 24 Oct 2024 07:00:00 -0400 Versatrim employees, including CEO Keith Medick and founder Thilo Hessler, delivered three truckloads of essential supplies to Western North Carolina communities affected by Hurricane Helene. Full Article
e v Lioncore Vietnam Adopts i4F Single-Panel Drop-Lock Flooring Technology By www.floortrendsmag.com Published On :: Thu, 31 Oct 2024 08:00:00 -0400 Vietnamese flooring manufacturer Lioncore Industries has licensed i4F's new HerringB/ONE technology, a simplified herringbone flooring system that eliminates the need for mirrored panels. The deal expands Lioncore's existing partnership with i4F and will streamline production while making installation more DIY-friendly. Full Article
e v Taylor Adhesive Zephyr Serves as a Moisture Vapor Barrier, Encapsulator and Primer Coating By www.floortrendsmag.com Published On :: Sat, 05 Oct 2024 09:00:00 -0400 Engineered to fight moisture, Zephyr can also be used as a primer, or even an encapsulator, eliminating the need to remove existing or cutback adhesive residue. Full Article
e v 3 Reasons to Optimize Food Production with Real-Time Video Monitoring By www.foodengineeringmag.com Published On :: Fri, 09 Aug 2024 07:00:00 -0400 When you think about video monitoring, the first thing that comes to mind is security. While that is a big perk indeed, there are much bigger benefits to implementing the right video monitoring system. Full Article
e v Questions / discussion about private jets, private vs. commercial, etc (2024 onwards) By www.flyertalk.com Published On :: Thu, 07 Nov 2024 10:58:30 GMT Are there any private jets that have at least one comfortable and real bed to sleep on - for a transatlantic overnight flight? Not talking about seats the go flat bed or even sofas that open up. A real bed... Full Article TravelBuzz
e v 'High tide by boat, low tide we walk': the everyday digital lives of girls in remote villages of Vanua Levu, Fiji. By ezproxy.scu.edu.au Published On :: Wed, 01 Dec 2021 00:00:00 -0500 Children's Geographies; 12/01/2021(AN 153655054); ISSN: 14733285Academic Search Premier Full Article FIJI TECHNOLOGICAL revolution DIGITAL technology EMOTIONS VILLAGES EVERYDAY life VIRTUAL communities SOCIAL media SOCIAL context
e v Whose voices? Whose knowledge? Children and young people’s learning about climate change through local spaces and indigenous knowledge systems. By ezproxy.scu.edu.au Published On :: Thu, 10 Nov 2022 00:00:00 -0500 Children's Geographies; 11/10/2022(AN 160144945); ISSN: 14733285Academic Search Premier Full Article
e v The street, children and parents: the views of children from Santiago de Chile. By ezproxy.scu.edu.au Published On :: Tue, 01 Aug 2023 00:00:00 -0400 Children's Geographies; 08/01/2023(AN 167303408); ISSN: 14733285Academic Search Premier Full Article SANTIAGO (Chile) CHILE PARENTS CHILEANS PARENT-child relationships DISCOURSE analysis MASS media & politics SOCIABILITY STREET children
e v 'I'm going to call my friend to join us': connections and challenges in online video interviews with children during COVID-19. By ezproxy.scu.edu.au Published On :: Thu, 01 Feb 2024 00:00:00 -0500 Children's Geographies; 02/01/2024(AN 175911764); ISSN: 14733285Academic Search Premier Full Article ONTARIO COVID-19 pandemic STREAMING video & television VIRTUAL communities CONSTRUCTION equipment VIDEOS EXIT interviewing
e v Israel's war on Gaza and the violation of children's rights. By ezproxy.scu.edu.au Published On :: Mon, 01 Apr 2024 00:00:00 -0400 Children's Geographies; 04/01/2024(AN 178088146); ISSN: 14733285Academic Search Premier Full Article GAZA Strip ISRAEL PALESTINE ISRAEL-Gaza conflict 2006- CHILDREN'S rights PALESTINIAN children ISRAELI-occupied territories CHILD welfare
e v 'The world is your oyster': mothers' perspectives on the value and purpose of an independent Forest School provision. By ezproxy.scu.edu.au Published On :: Thu, 01 Aug 2024 00:00:00 -0400 Children's Geographies; 08/01/2024(AN 178911407); ISSN: 14733285Academic Search Premier Full Article SCHOOL children CHILD development PARENTS MOTHERS PRIVATE schools THEMATIC analysis
e v Guidance | Joint targeted area inspection of the multi-agency response to children who are victims of domestic abuse Updated 12 September 2024 By ifp.nyu.edu Published On :: Sun, 20 Oct 2024 13:56:58 +0000 The post Guidance | Joint targeted area inspection of the multi-agency response to children who are victims of domestic abuse Updated 12 September 2024 was curated by information for practice. Full Article Guidelines Plus
e v Improving the visibility of older people in global statistics By ifp.nyu.edu Published On :: Fri, 01 Nov 2024 02:36:03 +0000 The post Improving the visibility of older people in global statistics was curated by information for practice. Full Article Grey Literature
e v Estimates of the very old, including centenarians, England and Wales: 2002 to 2023 By ifp.nyu.edu Published On :: Sun, 03 Nov 2024 12:37:19 +0000 The post Estimates of the very old, including centenarians, England and Wales: 2002 to 2023 was curated by information for practice. Full Article Grey Literature
e v A Pregnant Teenager Died After Trying to Get Care in Three Visits to Texas Emergency Rooms By ifp.nyu.edu Published On :: Mon, 04 Nov 2024 14:07:55 +0000 It took three ER visits and 20 hours before a hospital admitted Nevaeh Crain, 18, as her condition worsened. Doctors insisted on two ultrasounds to confirm “fetal demise.” She’s one of at least two Texas women who died under the state’s abortion ban. The post A Pregnant Teenager Died After Trying to Get Care in Three Visits to Texas Emergency Rooms was curated by information for practice. Full Article News
e v Graduate Concurrency Architecture Verification Engineer, Graduates, Cambridge, UK, Software Engineering By careers.peopleclick.com Published On :: Monday, September 28, 2020 10:23:00 AM EDT Concurrency architecture verification engineerAre you interested in concurrency, CPU design, and verification? Then we have just the opportunity for you.Arm uses innovative tools [1] for modelling and reasoning about concurrency in our products. Those tools serve different purposes, such as: clarifying our architecture specification [2], communicating with our partners, and enabling verification of our CPU hardware designs.This last point is at the intersection of architectural specification and CPU hardware design, which is where your role would be.We seek to encourage interaction between those activities within Arm and beyond: by working hand in hand with architects and CPU verification teams to understand their requirements, you will improve our methodology and tools. You will also be in charge of inventing and prototyping new ways to verify pre-silicon designs.This is an outstanding opportunity if you are interested in:developing open-source tools [3] which benefit the Arm ecosystem and wider communities such as language standard committees, compiler and kernel developers;furthering the understanding of an area that has been the subject of intense research in the last decade;demonstrating the impact of formal models on industrial products.Our tools are written in Ocaml and C; knowing those languages would be ideal, as well as a working knowledge of Linux, git and RTL.See also:[1] https://developer.arm.com/architectures/cpu-architecture/a-profile/memory-model-tool[2] https://developer.arm.com/docs/ddi0487/latest/arm-architecture-reference-manual-armv8-for-armv8-a-architecture-profile[3] http://diy.inria.fr[4] https://github.com/herd/herdtools7/ Full Article
e v Introduction to Authentic Voicework: Yoga of the Voice By indianapublicmedia.org Published On :: 15 Dec 2024 00:00:00 GMT Nourishing Heart Yoga Studio 582 E Hillside Drive in Bloomington, Indiana Saturday, December 14, 2024, 7 – 8:30pm Do you have a fear of singing or find singing to be intimidating? Here’s one for you: Join us Saturday, December 14, 7-8:30 PM at Nourishing Heart in Bloomington for an illuminating evening of 'Yoga of the Voice.’ Immerse yourself in a transformative experience blending deep relaxation and meditative-style singing to reduce your anxiety. If you're interested in sound healing or the expressive arts, you’ll love this! Bring a yoga mat and dress comfortably. Drop-ins welcome! Presenter: Stephanie Heidemann Contact: Stephanie Heidemann Cost: $22 Ticket Web Link: nourishingheartyoga.com… Communities: Bedford, Bloomington, Brown County, Columbus, Franklin, French Lick/West Baden, Greencastle, Greene County, Greensburg, Greenwood, Indianapolis, Kokomo, Martinsville, Seymour, Spencer, Statewide, Terre Haute More info: nourishingheartyoga.com… Full Article 2024/12/14 (Sat)
e v Introduction to Authentic Voicework: Yoga of the Voice By indianapublicmedia.org Published On :: 24 Nov 2024 00:00:00 GMT Nourishing Heart Yoga Studio 582 E Hillside Drive in Bloomington, Indiana Saturday, November 23, 2024, 7 – 8:30pm Do you have a fear of singing or find singing to be intimidating? Here’s one for you: Join us Saturday, November 23, 7-8:30 PM at Nourishing Heart in Bloomington for an illuminating evening of 'Yoga of the Voice.’ Immerse yourself in a transformative experience blending deep relaxation and meditative-style singing to reduce your anxiety. If you're interested in sound healing or the expressive arts, you’ll love this! Bring a yoga mat and dress comfortably. Drop-ins welcome! Presenter: Stephanie Heidemann Contact: Stephanie Heidemann Cost: $22 Ticket Web Link: nourishingheartyoga.com… Communities: Bedford, Bloomington, Brown County, Columbus, Franklin, French Lick/West Baden, Greencastle, Greene County, Greensburg, Greenwood, Indianapolis, Kokomo, Martinsville, Seymour, Spencer, Statewide, Terre Haute More info: nourishingheartyoga.com… Full Article 2024/11/23 (Sat)
e v Introduction to Authentic Voicework: Yoga of the Voice By indianapublicmedia.org Published On :: 16 Nov 2024 17:30:00 GMT Bloomington Yoga Collective116 W. 6th Street, Suite 110,Bloomington, Indiana 47404 Saturday, November 16, 2024, 12:30 – 2pm Do you have a fear of singing or find singing to be intimidating? Here’s one for you: Join us Saturday, November 16, 12:30-2PM at Bloomington Yoga Collective for an illuminating experience of 'Yoga of the Voice.’ Immerse yourself in a transformative experience blending deep relaxation and meditative-style singing to reduce your anxiety. If you're interested in sound healing or the expressive arts, you’ll love this! Bring a yoga mat and dress comfortably. Drop-ins welcome! Presenter: Stephanie Heidemann Contact: Stephanie Heidemann Cost: $22 Ticket Web Link: www.bloomingtonyogaco.com… Communities: Bedford, Bloomington, Brown County, Columbus, Franklin, French Lick/West Baden, Greencastle, Greene County, Greensburg, Greenwood, Indianapolis, Kokomo, Martinsville, Seymour, Spencer, Statewide, Terre Haute More info: www.bloomingtonyogaco.com… Full Article 2024/11/16 (Sat)
e v City Council Urged to Postpone Vote on Controversial Downtown Service District Contract By www.portlandmercury.com Published On :: Tue, 12 Nov 2024 17:00:00 -0800 Citing ethical issues and potential conflicts of interest, advocates want the city to halt a no-bid contract renewal that would funnel millions to the Portland Metro Chamber. by Courtney Vaughn For years, Portland has collected fees from property owners in enhanced service districts to pay for added cleaning and security services in designated areas. The districts are typically concentrated around businesses, offering private security, extra policing, janitorial services, and more recently, removal of homeless camps. Some stakeholders say the city has yet to confront the unique and outsized role of Portland’s most powerful business lobbying group at one enhanced service district (ESD) in particular—Downtown Portland Clean & Safe. This week, Portland City Council is scheduled to vote on a 116-acre expansion of the Downtown Portland Clean & Safe district, as well as a fee hike and a five-year management contract renewal for the district. Ahead of Wednesday’s vote, more than 100 Portlanders and over a dozen community groups are urging City Council to postpone the contract renewal that would funnel a hefty portion of a $58 million, no-bid contract to the Portland Metro Chamber. An open letter to city commissioners outlines a number of transparency and ethics issues surrounding the Clean & Safe contract, asking the Council vote to be tabled until a new Council is sworn in this January. Currently, the Downtown Portland Clean & Safe district is overseen by an organization of the same name, whose management has significant overlap with the executive leadership of the Portland Metro Chamber (formerly the Portland Business Alliance). A large chunk of funding for the Metro Chamber’s leadership staff comes from a lucrative contract to oversee the Downtown Portland Clean & Safe ESD. That means a private group that lobbies the city on behalf of private business interests is being paid millions in public money to oversee a service district that includes a large swath of its own dues-paying members. The downtown district also includes several government agencies and properties that pay into the ESD—including Portland City Hall. Moreover, community groups say the contract and service delivery model are convoluted at best, with next to no oversight from the city. The letter’s signatories say the petition for district expansion, and the accompanying contract renewal “raises serious concerns related to affordability, efficient use of public resources, accountability, and transparency.” “The City contracts with Clean & Safe, which subcontracts with other organizations to carry out cleaning and safety services. Yet the executive director of Clean & Safe is simultaneously an employee of the Portland Business Alliance, which is also a subcontractor of Clean & Safe,” the open letter to Council states. “Unclear lines of oversight make it difficult for ratepayers or the public to hold anyone accountable. Even more concerning, the contract allocates significant overhead to the Portland Business Alliance, the city’s most active lobbying organization.” It's a contract that mystifies everyone from accountants, to ratepayers, and even auditors. A 2020 city audit of Portland's ESDs found "little oversight" of the privately funded public service districts and noted "complicated governance and management systems" that obfuscate public access to basic information such as budgets and subcontracts. Not long after the city audit, a local business executive spoke out about the questionable business arrangement baked into the Clean & Safe contract. When she did, she was allegedly threatened with a lawsuit from the Portland Business Alliance. Since then, other local government watchdogs have taken note, but gotten little traction with city leadership. “I think this council has an ethical responsibility to answer all these questions for the voters, or wait,” Diane Goodwin, a member of local political advocacy group Portland For All, says. Cleaning services praised; expenses questioned It's unclear what Clean & Safe's latest budget includes. A 2021 budget calculated total expenses at around $5 million, including about $858,000 in salaries. Exactly what portion of staff is covered in those salary expenses is murky. Both the Metro Chamber and Downtown Clean & Safe share staff. In fact, the Chamber's CEO and president, Andrew Hoan, is also the CEO and president of Downtown Clean & Safe. The 2021 budget shows $243,000 in "shared administration" salary costs. Tax documents from 2022 show Hoan drew a $333,000 salary from the Chamber that year. The two organizations also share an executive assistant and an advocacy coordinator. Clean & Safe's operations director and executive director are also listed as part of the Chamber's staff. The Clean & Safe executive director drew a $154,000 salary from the Chamber that same year. Businesses and commercial property owners in the district overwhelmingly support the expansion, saying the frequent cleaning and beefed up security have improved downtown Portland and made it safer for workers and visitors. “We want our associates to feel safe coming into work,” Kelly Mullen, president of Portland’s Safeway and Albertsons division, told the Council on October 31 during its initial consideration of the contract and ESD expansion. Mullen said recently, the Safeway location at 10th and Jefferson has had to reduce store hours and close off an entrance, to improve safety at the grocery store. “We want to be part of the solution and really make our community thrive,” Mullen said. The council also heard from the principal of a private school advocating for the district expansion so her students and staff could receive extra security and clean-up around the campus. One element of Downtown Clean & Safe that’s lauded by nearly every district member, even critics, is the Clean Start program, run by Central City Concern. The program offers janitorial jobs cleaning city streets to people transitioning out of homelessness. For many, it offers a fresh start and a path toward self-sufficiency. City staff and Clean & Safe reps say the expanded district and new proposed rate structures will offer more transparency, reasonable fee calculations, inflation adjustments, and a cap on rates for condo owners. Several residential ratepayers say the whole Clean & Safe arrangement leaves them with more questions than services received. John Pumphrey owns a condominium in the downtown district. He and other condo owners say the services they pay for are often duplicative of private security and janitorial services they already pay for through their homeowners association. They also say the services serve mainly to benefit businesses, not residents. “I’m a condo owner in downtown Portland and our building pays $24,000 a year to Clean & Safe and for this, [we] receive next to nothing,” Pumphrey told the Council, asking them to vote against the contract renewal. “What’s really irritating to some of us about Clean & Safe is that 50 percent of what we contribute … is skimmed off the top by the Portland Metro Chamber.” Pumphrey isn’t the only one critical of the unusually high compensation provided to Portland Metro Chamber staff from the Downtown Clean & Safe contract. The open letter to City Council also makes mention of the compensation arrangement, asserting the Clean & Safe contract “pays nearly 50 percent of Business Alliance executive salaries in addition to up to 30% in administrative overhead.” “Many of these executives appear in City lobbying records and in state filings for PACs that advocate for private business interests, often directly in conflict with the will of the voting public,” the letter reads. “It is inappropriate to use public resources to offset the cost of business lobbying.” Devin Reynolds, the city's ESD coordinator, said the arrangement between the Metro Chamber and Dowtown Clean & Safe isn't an anomaly. “Having an ESD contract with a third party to fulfill some, or all their service areas is indeed common across business improvement districts, business improvement areas, and enhanced services districts,” Reynolds told the Mercury earlier this year. Commonplace or not, some downtown ESD ratepayers say they’ve been cut off from any meaningful participation in their district’s oversight or decisions. Anita Davidson, a condo owner in the downtown district, told the Mercury that for years, condo owners have had no representation in district leadership, and there is little to no transparency around operational decisions. “As residential people, we don’t feel we belong there. We don't have a vote in who runs Clean & Safe,” she said. “We can’t even join Portland Metro Chamber, because it's for businesses. I’d like to see Clean & Safe become a public nonprofit. That would solve a lot of things. I still have to make a public records request [just] to see their budget.” In an effort to appease homeowners, the new contract includes a fee cap on residential units. It’s a nice accommodation, but homeowners in the industry-dominated district say what they really want is a way to opt out. There currently is no mechanism to do that, and the process for annexing additional property into an ESD doesn’t require a vote from affected property owners. It’s left up to City Council to approve. Current standards only require the city to notify affected property owners by mail and hold public hearings where they can chime in. “Unfortunately for ratepayers, the city has not yet, after 30 years, adopted standards for formation, renewal, or expansion of the ESDs,” Davidson told Council. “At some point, we hope and expect that this will happen, although listening tonight, it sounds like it's an all-in-one thing.” Other district members say they disagree with their tax revenue being used to initiate homeless sweeps, and pay for increased police presence. That’s especially true in the case of Sisters of the Road, a homeless services nonprofit and member of the Downtown Portland Clean & Safe district. “From 2016-2020, unhoused residents accounted for over half of arrests made in Portland. Their charges were primarily nonviolent, survival crimes. That same data showed that people are 20 times more likely to experience criminalization in Downtown Clean & Safe versus other areas of the city,” Lauren Armony, program director at Sisters of the Road, told the city in written testimony earlier this year. “Hyper-surveillance has not made our neighborhood any healthier or safer, but further entrenched vulnerable individuals in the cycle of incarceration and poverty.” Organizations like Sisters of the Road say they're irked that the ESD funnels its members’ taxes into the Metro Chamber, which has powerful influence over city politics and often advocates against the city’s vulnerable, unhoused residents–the same population Sisters of the Road is trying to help. The Clean & Safe contract and district expansion are currently scheduled for a second reading and vote by Portland City Council on Wednesday. Full Article News Politics
e v Patient Zero: The Vector By beta.prx.org Published On :: Thu, 29 Aug 2019 18:15:51 -0000 A perfect carrier of disease. A race underneath your skin. The part we know, before we get to the parts we don't. Click hereto donate $20 and get ad-free episodes of Patient Zero a week early and bonus content. Full Article
e v Minnesota attorney general on Trump: ‘If he violates the rights of people, we’re going to sue’ By www.mprnews.org Published On :: Tue, 12 Nov 2024 21:20:00 +0000 The second-term DFLer says he’ll challenge Trump if Republicans push politics that contradict Minnesota laws. Full Article
e v It’s Veterans Day. The VA says it can’t help thousands of vets it left stranded By www.mprnews.org Published On :: Mon, 11 Nov 2024 10:00:00 +0000 An NPR investigation finds thousands of veterans were pushed into high-cost mortgages by a program that was meant to help them. A rescue plan being rolled out by the Department of Veterans Affairs is excluding many vets who need help. Full Article
e v Inside a Christian woman's fight to shut down Pornhub for distributing child abuse videos By www.christianpost.com Published On :: Sat, 07 Sep 2024 07:36:00 -0400 Laila Mickelwait has fought against sex trafficking for decades, and her latest memoir recounts her efforts to expose Pornhub and also how her Christian faith filled her with the strength to take on Goliath. Full Article
e v COGIC bishop anoints Kamala Harris with prayer, declares ‘I believe we have the victory’ By www.christianpost.com Published On :: Mon, 04 Nov 2024 11:51:27 -0500 Despite being rebuked by Pastor Donnie Swaggart for endorsing Vice President Kamala Harris to become the next president of the United States, Bishop John Drew Sheard, presiding bishop and chief apostle of the Church of God in Christ, defiantly anointed her with prayer before his congregation Sunday after declaring, “I believe we have the victory.” Full Article
e v Gateway Church edits advice to abuse victims: ‘Go to the police first,’ not church By www.christianpost.com Published On :: Tue, 05 Nov 2024 14:37:15 -0500 A day after urging sex abuse victims of current or former leaders of the embattled Gateway Church in Southlake, Texas, to report their abuse to elders, longtime elder at the megachurch, Tra Willbanks, revised his advice on Sunday urging them instead to “go to the police first.” Full Article
e v World must be more attentive to male virgins By english.pravda.ru Published On :: Fri, 06 May 2016 11:17:00 +0300 Source: REX There are a number of factors that can change the general public’s attitude to late virginity among men. Reason One: it is not so easy for a man to lose virginity Historically, the first sexual experience is a subject of extraordinary pride for men. That is why most boys grow up with the aim of losing virginity as soon as possible. According to France’s National Institute for Demographic Studies (INED), an average West European man has his first sex at age 17. If it takes longer, boys think that there is something amiss with them and unintentionally enhance the possibility of turning from a proud eagle into a timid sparrow. There is another stereotype: men are the first to show an initiative. If they do not, they are automatically associated with a sniveler, a loser and an object of pity. Full Article Health
e v El personal de TDI estará ofreciendo ayuda en persona para los dueños de vivienda con daños por el tornado By www.tdi.texas.gov Published On :: Fri, 27 Jan 2023 00:00:00 CST Si su casa sufrió daños por el severo estado del tiempo que impactó el sureste de Texas esta semana, contacte a su compañía de seguros para presentar una reclamación lo antes posible. Full Article
e v Toshiba’s next-generation S300 Pro Surveillance HDDs for large-scale video surveillance systems By www.retailtechnologyreview.com Published On :: Toshiba Electronics Europe GmbH (Toshiba) has introduced its next-generation S300 Pro Surveillance Hard Disk Drives (HDDs) targeting the latest requirements in the surveillance storage market. Full Article Surveillance and Security
e v Bazaarvoice launches integrated Social Content solution, Bazaarvoice Vibe By www.retailtechnologyreview.com Published On :: Tue, 13 Nov 2260 17:28:41 +0000 At GroceryShop, Bazaarvoice, the platform for full-funnel authentic user-generated content (UGC) and social commerce solutions, announced Bazaarvoice Vibe – a comprehensive solution designed to help marketers source, amplify and optimise user- and creator-generated content across all channels, all from one place. Global general availability begins 1 November. Full Article Internet Retailing Retail Supply Chain
e v SUZOHAPP appoints Simon James as New Executive Vice President of Retail & Transportation, EMEA By www.retailtechnologyreview.com Published On :: SUZOHAPP is pleased to announce the appointment of Simon James as its new Executive Vice President of Retail & Transportation.Simon joined SUZOHAPP as Managing Director (MD) of the United Kingdom & Ireland, on September 1, 2018 and has made a very positive impact on our business there in a year's time. Full Article Critical Issues EPoS Systems Kiosk Technology
e v Why the V Engine Remains a Top Choice for Car Enthusiasts By auto.howstuffworks.com Published On :: Fri, 18 Oct 2024 10:05:02 -0400 The V engine has been a favorite among car lovers for many years. Known for its unique design and powerful performance, it is the engine of choice for many vehicles today. Full Article
e v Han Kang's 'The Vegetarian' to be Made into Italian Play By world.kbs.co.kr Published On :: Sat, 12 Oct 2024 14:44:18 +0900 [Culture] : South Korea's first Nobel Prize winner in literature Han Kang's bestselling novel "The Vegetarian" will be made into a play in the Italian language. According to the Korean Cultural Center in Rome, Italian theater company INDEX is set to stage the play in nine major cities of Italy and France, including ...[more...] Full Article Culture
e v What Is Imitation Crab Meat? Is the Crab Substitute Vegan? By recipes.howstuffworks.com Published On :: Fri, 16 Feb 2024 12:45:51 -0500 If you've had a grocery store California roll or mixed seafood salad, you've probably eaten imitation crab meat. But what is imitation crab, exactly? Full Article
e v BGS launches project to enhance value of ground investigation data - Ground Engineering By news.google.com Published On :: Fri, 05 Apr 2024 07:00:00 GMT BGS launches project to enhance value of ground investigation data Ground Engineering Full Article
e v High-resolution double vision of the allosteric phosphatase PTP1B By journals.iucr.org Published On :: 2024-01-01 Protein tyrosine phosphatase 1B (PTP1B) plays important roles in cellular homeostasis and is a highly validated therapeutic target for multiple human ailments, including diabetes, obesity and breast cancer. However, much remains to be learned about how conformational changes may convey information through the structure of PTP1B to enable allosteric regulation by ligands or functional responses to mutations. High-resolution X-ray crystallography can offer unique windows into protein conformational ensembles, but comparison of even high-resolution structures is often complicated by differences between data sets, including non-isomorphism. Here, the highest resolution crystal structure of apo wild-type (WT) PTP1B to date is presented out of a total of ∼350 PTP1B structures in the PDB. This structure is in a crystal form that is rare for PTP1B, with two unique copies of the protein that exhibit distinct patterns of conformational heterogeneity, allowing a controlled comparison of local disorder across the two chains within the same asymmetric unit. The conformational differences between these chains are interrogated in the apo structure and between several recently reported high-resolution ligand-bound structures. Electron-density maps in a high-resolution structure of a recently reported activating double mutant are also examined, and unmodeled alternate conformations in the mutant structure are discovered that coincide with regions of enhanced conformational heterogeneity in the new WT structure. These results validate the notion that these mutations operate by enhancing local dynamics, and suggest a latent susceptibility to such changes in the WT enzyme. Together, these new data and analysis provide a detailed view of the conformational ensemble of PTP1B and highlight the utility of high-resolution crystallography for elucidating conformational heterogeneity with potential relevance for function. Full Article text
e v Online carbohydrate 3D structure validation with the Privateer web app By journals.iucr.org Published On :: 2024-01-24 Owing to the difficulties associated with working with carbohydrates, validating glycan 3D structures prior to deposition into the Protein Data Bank has become a staple of the structure-solution pipeline. The Privateer software provides integrative methods for the validation, analysis, refinement and graphical representation of 3D atomic structures of glycans, both as ligands and as protein modifiers. While Privateer is free software, it requires users to install any of the structural biology software suites that support it or to build it from source code. Here, the Privateer web app is presented, which is always up to date and available to be used online (https://privateer.york.ac.uk) without installation. This self-updating tool, which runs locally on the user's machine, will allow structural biologists to simply and quickly analyse carbohydrate ligands and protein glycosylation from a web browser whilst retaining all confidential information on their devices. Full Article text
e v Real-time analysis of liquid-jet sample-delivery stability for an X-ray free-electron laser using machine vision By journals.iucr.org Published On :: This paper describes real-time statistical analysis of liquid jet images for SFX experiments at the European XFEL. This analysis forms one part of the automated jet re-alignment system for SFX experiments at the SPB/SFX instrument of European XFEL. Full Article text
e v Crystal structure of 1,10-phenanthrolinium violurate violuric acid pentahydrate By journals.iucr.org Published On :: The crystal structure of the co-crystal salt solvate 1,10-phenanthrolinium violurate violuric acid pentahydrate features a tri-periodic hydrogen-bonded network with the violurate and violuric acid residues each assembled into tapes and the phenanthrolinium cations residing in channels. Full Article text
e v Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity By journals.iucr.org Published On :: 2024-04-24 Human peptidylarginine deiminase isoform VI (PAD6), which is predominantly limited to cytoplasmic lattices in the mammalian oocytes in ovarian tissue, is essential for female fertility. It belongs to the peptidylarginine deiminase (PAD) enzyme family that catalyzes the conversion of arginine residues to citrulline in proteins. In contrast to other members of the family, recombinant PAD6 was previously found to be catalytically inactive. We sought to provide structural insight into the human homologue to shed light on this observation. We report here the first crystal structure of PAD6, determined at 1.7 Å resolution. PAD6 follows the same domain organization as other structurally known PAD isoenzymes. Further structural analysis and size-exclusion chromatography show that PAD6 behaves as a homodimer similar to PAD4. Differential scanning fluorimetry suggests that PAD6 does not coordinate Ca2+ which agrees with acidic residues found to coordinate Ca2+ in other PAD homologs not being conserved in PAD6. The crystal structure of PAD6 shows similarities with the inactive state of apo PAD2, in which the active site conformation is unsuitable for catalytic citrullination. The putative active site of PAD6 adopts a non-productive conformation that would not allow protein–substrate binding due to steric hindrance with rigid secondary structure elements. This observation is further supported by the lack of activity on the histone H3 and cytokeratin 5 substrates. These findings suggest a different mechanism for enzymatic activation compared with other PADs; alternatively, PAD6 may exert a non-enzymatic function in the cytoplasmic lattice of oocytes and early embryos. Full Article text
e v Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options By journals.iucr.org Published On :: 2024-04-24 The large Bunyavirales order includes several families of viruses with a segmented ambisense (−) RNA genome and a cytoplasmic life cycle that starts by synthesizing viral mRNA. The initiation of transcription, which is common to all members, relies on an endonuclease activity that is responsible for cap-snatching. In La Crosse virus, an orthobunyavirus, it has previously been shown that the cap-snatching endonuclease resides in the N-terminal domain of the L protein. Orthobunyaviruses are transmitted by arthropods and cause diseases in cattle. However, California encephalitis virus, La Crosse virus and Jamestown Canyon virus are North American species that can cause encephalitis in humans. No vaccines or antiviral drugs are available. In this study, three known Influenza virus endonuclease inhibitors (DPBA, L-742,001 and baloxavir) were repurposed on the La Crosse virus endonuclease. Their inhibition was evaluated by fluorescence resonance energy transfer and their mode of binding was then assessed by differential scanning fluorimetry and microscale thermophoresis. Finally, two crystallographic structures were obtained in complex with L-742,001 and baloxavir, providing access to the structural determinants of inhibition and offering key information for the further development of Bunyavirales endonuclease inhibitors. Full Article text
e v Crystal structure via fluctuation scattering By journals.iucr.org Published On :: 2024-06-06 Crystallography is a quintessential method for determining the atomic structure of crystals. The most common implementation of crystallography uses single crystals that must be of sufficient size, typically tens of micrometres or larger, depending on the complexity of the crystal structure. The emergence of serial data-collection methods in crystallography, particularly for time-resolved experiments, opens up opportunities to develop new routes to structure determination for nanocrystals and ensembles of crystals. Fluctuation X-ray scattering is a correlation-based approach for single-particle imaging from ensembles of identical particles, but has yet to be applied to crystal structure determination. Here, an iterative algorithm is presented that recovers crystal structure-factor intensities from fluctuation X-ray scattering correlations. The capabilities of this algorithm are demonstrated by recovering the structure of three small-molecule crystals and a protein crystal from simulated fluctuation X-ray scattering correlations. This method could facilitate the recovery of structure-factor intensities from crystals in serial crystallography experiments and relax sample requirements for crystallography experiments. Full Article text
e v USI Money plans to integrate Visa Direct By thepaypers.com Published On :: Tue, 12 Nov 2024 08:24:00 +0100 UK-based USI Money has announced its... Full Article