can After storm over allegations, Australia Today clarifies ban was by Meta platforms, not Canadian government By www.thehindu.com Published On :: Mon, 11 Nov 2024 21:36:13 +0530 The Ministry of External Affairs, which had slammed Canada over the allegations last week, has been silent over clarification Full Article India
can Amid threats of violent protests, Brampton Triveni temple cancels life certificate event By www.thehindu.com Published On :: Tue, 12 Nov 2024 08:01:16 +0530 “We are deeply saddened that Canadians now feel unsafe coming to Hindu Temples in Canada” Full Article World
can Justin Welby, Archbishop of Canterbury, resigns over abuse scandal By www.thehindu.com Published On :: Tue, 12 Nov 2024 19:55:10 +0530 Archbishop Welby, the spiritual leader of 85 million Anglicans worldwide, had faced calls to resign after a report last week found he had taken insufficient action to stop a person it described as arguably the Church of England’s most prolific serial abuser Full Article World
can Police ask devotees to exercise caution while taking holy dip in canals, rivers in Andhra Pradesh’s Kurnool By www.thehindu.com Published On :: Sat, 02 Nov 2024 13:07:14 +0530 “Police bandobust would be arranged at important points as people throng river banks,” SP Bindhu Madhav said and asked the devotees to follow the directions and suggestions of the Police for incident-free festivities Full Article Andhra Pradesh
can Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00492B, PaperJuan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi WangA novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2359-2367DOI: 10.1039/D4AY00151F, PaperDingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling WuSartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00146J, PaperDumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan DingA fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can How mobile data can help rationalise bus routes By www.thehindubusinessline.com Published On :: Wed, 01 May 2013 16:35:55 +0530 Full Article R Dinakaran
can Canadian frostbite: On the India-Canada diplomatic war By www.thehindu.com Published On :: Thu, 17 Oct 2024 00:20:00 +0530 India must consider the impact of its next steps on its diplomacy and image Full Article Editorial
can Complicit: On India and the U.S and Canada cases By www.thehindu.com Published On :: Mon, 21 Oct 2024 00:30:00 +0530 India must come clean on its stance on transnational killings Full Article Editorial
can The Raj & DK Line-Up You Cannot Miss By www.rediff.com Published On :: Sukanya Verma looks at their eclectic career of over two decades as their latest offering Citadel: Honey Bunny, the Indian leg of the Russo Brothers globetrotting spy universe series, drops on Amazon Prime Video on November 7. Full Article
can Synthesis and cytotoxic activity of madecassic acid–silybin conjugate compounds in liver cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3418-3432DOI: 10.1039/D4MD00170B, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Chien Van Tran, Thao Thi Phuong Tran, Anh The Nguyen, Loc Van Tran, Ninh Thi Pham, Luu Thi Nguyen, Dung Thi Nguyen, Michelle D. Garrett, Nga Thi Nguyen, Thao Thi Do, Christopher J. Serpell, Sung Van TranMadecassic acid and silybin have been conjoined to produce hybrid compounds with improved and different activity against liver cancer cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Semisynthetic phytochemicals in cancer treatment: a medicinal chemistry perspective By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3345-3370DOI: 10.1039/D4MD00317A, Review ArticleMeghna Arora, Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Prateek Pathak, Maria Grishina, Jagat Pal Yadav, Amita Verma, Pradeep KumarSemisynthetic phytochemicals in cancer treatment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3444-3459DOI: 10.1039/D4MD00318G, Research ArticleAnuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar MaitiNiloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3433-3443DOI: 10.1039/D4MD00468J, Research ArticleMeijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing LiA synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3529-3557DOI: 10.1039/D4MD00481G, Research ArticleMohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai AdelDiscovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3460-3468DOI: 10.1039/D4MD00405A, Research ArticleXiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli BiSchematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024) By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3371-3394DOI: 10.1039/D4MD00384E, Review ArticleDebasis Das, Lingzhi Xie, Jian HongProspects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of Myristica malabarica Lam. By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3558-3575DOI: 10.1039/D4MD00391H, Research ArticlePothiyil S. Vimalkumar, Neethu Sivadas, Vishnu Priya Murali, Daisy R. Sherin, Madhukrishnan Murali, Anuja Gracy Joseph, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar MaitiMalabaricone A isolated from Myristica malabarica induces apoptosis in triple-negative breast cancer cells through intrinsic and extrinsic pathways, which is validated through in vitro and in silico studies and resembles a potent phyto-entity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00517A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca ReA novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Design, synthesis, and evaluation of benzhydrylpiperazine-based novel dual COX-2/5-LOX inhibitors with anti-inflammatory and anti-cancer activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00471J, Research ArticlePoorvi Saraf, Bhagwati Bhardwaj, Akash Verma, Mohammad Aquib Siddiqui, Himanshu Verma, Pradeep Kumar, Samridhi Srivastava, Sairam Krishnamurthy, Saripella Srikrishna, Sushant Kumar ShrivastavaScreening piperazine derivatives via ChEMBL database led to the design and synthesis of novel dual COX-2/5-LOX inhibitors with strong anti-inflammatory, analgesic, and anti-cancer activity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00617H, Research ArticleAida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü BeydemirIn this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Ligand-centred phenotype-driven development of potent kinase inhibitors against oesophageal cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00579A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cecilia C. Ayala-Aguilera, Yang Ge, Álvaro Lorente-Macías, Benjamin N. Jones, Catherine Adam, Neil O. Carragher, Asier Unciti-BrocetaA ligand-centred strategy combined with phenotypic screening was used to develop novel antiproliferative inhibitors against oesophageal cancer and identified a lead compound that induces potent anticancer activity and inhibits Aurora kinase A.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00553H, Research ArticleStefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro CosconatiNon-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can Technical, preclinical, and clinical developments of Fc-glycan-specific antibody–drug conjugates By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00637B, Review Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Qiang Yang, Yunpeng LiuFc-glycan-specific ADC is a significant advance in site-specific ADCs for cancer therapy. Notably, JSKN003 and IBI343 have demonstrated promising results in phase 1 clinical trials and are advancing into phase 3 studies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
can 548: Infinite Canvas, Luro + Figma, and Scraping or Crawling By shoptalkshow.com Published On :: Mon, 16 Jan 2023 10:41:42 +0000 What's going to happen to homework with AI? Thoughts on infinite canvas which leads into Luro and Sigma integration, and Chris gets nerdsniped and tries to scrap (or should he crawl?) websites for data. Full Article All Episodes chatgpt infinite canvas Luro
can 608: Can WordPress Kill Your Resume, Fav Parts of Web Dev, Exploring HTMX, and more! By shoptalkshow.com Published On :: Mon, 25 Mar 2024 07:55:38 +0000 We're opening up the ShopTalk mailbag and answering your questions, including does WordPress on your resume kill your job chances, what are our fav and least fav parts of web dev, our thoughts on HTMX, and what is it like to use pnpm instead of npm. Full Article All Episodes HTMX npm pnpm Wordpress
can Can Chennai change its energy consumption patterns? By www.thehindu.com Published On :: Fri, 05 Dec 2014 17:09:43 +0530 In creating energy-efficient cities, India will do well to model its development on its own age-old techniques, says Durganand Balsavar Full Article Property Plus
can How ‘priority sector’ status can rev up Jan Dhan banking By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 21:31:00 +0530 How regulation can nudge private banks to promote financial inclusion Full Article Current Account
can Flat organisation believers: Can you imagine a world without managers? By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:24:36 +0530 What does a manager do that we keep hiring new ones or keep promoting more of them? Which managerial layer is the most important? Full Article Corporate File
can Galathea Bay: New major port can be game changer By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 19:56:00 +0530 Transshipment port at Galathea Bay is strategically located on the East-West international trade and shipping route Full Article Logistics
can How radio waves can power smart cities By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 21:40:29 +0530 Practically omnipresent, thanks to human activity, radio frequency is the new area of focus for energy harvesting technology Full Article Science and Technology
can Can we escape the gas chamber we have walked into? By www.thehindubusinessline.com Published On :: Sun, 10 Nov 2024 20:10:58 +0530 All countries are falling short of their promise to do their mite for climate action Full Article Clean Tech
can Jamiat cautions NDA partners, says ‘crutches’ cannot escape responsibility for Waqf Bill By www.thehindu.com Published On :: Mon, 04 Nov 2024 21:07:19 +0530 The Jamiat Ulama-i-Hind urged NDA partners TDP and JD(U) to heed Muslim sentiments on the contentious issue surrounding the Waqf (Amendment) Bill, 2024 Full Article India
can Cannot change rules of the game once recruitment to public services commences: SC By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:49:04 +0530 The Constitution Bench says laws, rules and procedure governing recruitments to public services must be governed by the overarching principles of fundamental rights of equality and non-discrimination Full Article India
can Delhi cop Nidhin Valsan’s inspiring journey from arresting cancer to Ironman finish line By www.thehindu.com Published On :: Fri, 08 Nov 2024 02:05:22 +0530 Diagnosed with stage 4 non-Hodgkin’s lymphoma in 2021, IPS officer Nidhin Valsan resurrected himself by competing the Ironman triathlon and writing his memoir because he hopes to be a good influence on other cancer patients Full Article Delhi
can Man stabs mother in Delhi’s Badarpur for not ‘allowing him’ to migrate to Canada By www.thehindu.com Published On :: Sun, 10 Nov 2024 00:37:44 +0530 Full Article Delhi
can Security upped outside Canadian High Commission due to protest against temple attack By www.thehindu.com Published On :: Sun, 10 Nov 2024 16:13:43 +0530 The Hindu Sikh Global Forum members are marching towards the High Commission in the Chanakyapuri area Full Article Delhi
can Hurricane Rafael - Storm Updates By www.arrl.org Published On :: Tue, 05 Nov 2024 11:00:00 -0600 Tuesday, November 5, 2024, 11:00 AM Eastern Update:The following information is from the Hurricane Watch Net:The Hurricane Watch Net will be activated today, Tuesday, as planned, with one minor update. After further review of the timing of the storm and the distance from land, we need to modify our plans. All will remain the same with the exception that we will now operate overnightActivation P... Full Article
can Amateur Radio Activated for Late Season Hurricane By www.arrl.org Published On :: Fri, 08 Nov 2024 13:05:00 -0600 A rare November hurricane made landfall in western Cuba as a Category 3 storm Wednesday and continued to move slowly toward the northwest Thursday morning. Volunteer ham radio operators were there to provide surface reports to the National Hurricane Center in Miami.Hurricane Rafael left Cuba’s 10 million residents without power and on Thursday afternoon was a Category 2 storm moving away from C... Full Article
can Can India arrest income inequality? By www.thehindubusinessline.com Published On :: Sun, 26 Jul 2020 20:12:21 +0530 Thomas Piketty’s prescriptions are too radical. Dattopant Thengadi’s vision is more useful for us Full Article Books
can Centre to provide 15,000 women self help groups with drones that can be rented out for agricultural purposes By www.thehindu.com Published On :: Wed, 29 Nov 2023 17:14:01 +0530 The scheme will help in infusing advanced technology in agriculture for improved efficiency, enhance crop yield and reduced cost of operation for the benefit of farmers Full Article Agri-Business
can MSP law cannot be brought in a hurry; farmers should come forward for talks with govt: Arjun Munda By www.thehindu.com Published On :: Tue, 13 Feb 2024 17:35:17 +0530 Union Agriculture Minister Arjun Munda cautioned protesting farmers about some elements usurping their protest for political benefits Full Article Agriculture
can How can small-scale farmers benefit from trees on farms? By www.thehindu.com Published On :: Thu, 18 Apr 2024 05:30:00 +0530 The adoption of agroforestry at scale in India by smallholders is currently stymied by ecological and socio-economic factors Full Article Environment
can The certainty trap [electronic resource] : why we need to question ourselves more--and how we can judge others less / Ilana Redstone ; foreword by Joe Walsh. By darius.uleth.ca Published On :: Durham, North Carolina : Pitchstone Publishing, [2024] Full Article
can Can Bumrah Be World Cup 2023's MVP? By www.rediff.com Published On :: Mon, 30 Oct 2023 11:04:26 +0530 Srinivas Bhogle and Purnendu Maji present Rediff.com's Most Valuable Player Index after 29 World Cup 2023 games. Full Article
can China slowdown ‘a significant risk’ for global economy By www.thehindu.com Published On :: Fri, 27 May 2016 00:00:00 +0530 There has been a sharp contraction in China’s imports over the past year Full Article Mumbai Capital
can How Facebook can decide the price of your house By www.thehindu.com Published On :: Tue, 31 May 2016 00:00:00 +0530 Full Article Mumbai Capital
can Forbes’s list of self-made American women has two with India connect By www.thehindu.com Published On :: Fri, 03 Jun 2016 00:00:00 +0530 Full Article Mumbai Capital
