The post Antipsychotic Drugs: A Concise Review of History, Classification, Indications, Mechanism, Efficacy, Side Effects, Dosing, and Clinical Application was curated by information for practice.

Journal of the American Psychiatric Nurses Association, Ahead of Print. Background:Using long-acting injectable (LAI) antipsychotic medications can improve the outcomes of patients with schizophrenia, such as reducing symptom severity and hospitalization risk. However, the outcomes of switching from oral to LAI antipsychotic medications are unclear.Aims:The purpose of this review is to provide a summary of […]

The post Clinical, Quality of Life, and Health Care Utilization Outcomes of Switching the Administration Route of Antipsychotic Medications Among People With Schizophrenia Spectrum Disorder: A Systematic Review and Meta-Analysis was curated by information for practice.

The post Disaster Risk Communication Hub: Simple guidance and practical tips for practitioners was curated by information for practice.

The post Improving Financial Stability for Renters through Partnerships Between Local Housing and Financial Empowerment Service Providers was curated by information for practice.

The post National Institute for Health and Care Research: Research Professorships (Closes 11 Dec) was curated by information for practice.

The post BA/Leverhulme Senior Research Fellowships (Deadline date: 13 Nov ) was curated by information for practice.

The post Official Development Assistance: Global Innovation Fellowships (Expressions of interest must be submitted by 6 Nov) was curated by information for practice.

1202 E 38th St, Indianapolis, IN 46205
Friday, November 8, 9am – Tuesday, November 12, 2024, 8pm

Prepare for the ultimate culinary showdown at the 2024 World Food Championships (WFC)!

Over 1,500 chefs, home cooks, and professional teams from around the globe will compete for the coveted title of World Food Champion and a share of hundreds of thousands of dollars in prize money.
From sizzling steaks to decadent desserts, the WFC showcases ten official categories, offering a feast for the eyes and the taste buds. Whether you’re a passionate foodie, an aspiring chef, or just looking for a fun and delicious experience, the WFC has something for everyone.

Event Highlights:
Date: November 8-12, 2024
Location: 1202 E 38th St, Indianapolis, IN 46205
Special Features: Live cooking demos, tasting experiences, and opportunities to meet culinary stars!

Don’t miss out on this exciting event celebrating culinary creativity and excellence. Tickets are on sale now! For more information and to purchase tickets, visit worldfoodchampionships.com.


Follow on social media for the latest updates and behind-the-scenes action:
Facebook: World Food Championships
Instagram: @worldfoodchampionships
Twitter: @WorldFoodChamp

Ticket Web Link: www.indianastatefair.com…
Communities: Bedford, Bloomington, Brown County, Columbus, Franklin, French Lick/West Baden, Greencastle, Greene County, Greensburg, Greenwood, Indianapolis, Kokomo, Martinsville, Seymour, Spencer, Statewide, Terre Haute
More info: worldfoodchampionships.com

Portland will have the most racially diverse City Council the city has ever seen, with a progressive majority. by Courtney Vaughn

A fourth round of preliminary election results was released Friday, showing little to no changes in presumptive winners. That means Portlanders now have a clear idea of what the city's future leadership will be, come January.

Portland City Council is likely to have a progressive majority and for the first time, and a roughly 40 percent BIPOC Council.

Portland Mayor-elect Keith Wilson is slated to receive onboarding and training at City Hall starting next month, before the new City Council and mayor are sworn in in January.

In District 1, Candace Avalos, who previously ran for a seat on Portland City Council and served on Portland's Charter Commission, is leading handily and is a presumptive winner. She will most likely serve alongside former Multnomah County Commissioner Loretta Smith and Jamie Dunphy, whose career has been spent helping to shape public policy while formerly working for US Sen. Jeff Merkley and the late Portland City Commissioner Nick Fish. Dunphy has recently led the charge to stop a Live Nation music venue from being developed in Southeast Portland. While Dunphy is leading for third place, he currently sits at just 23 percent, which is less than the 25 percent threshold for election. County officials say that can happen when ballots become "exhausted." Dunphy will likely still win election.

In District 2, Elana Pirtle-Guiney, Sameer Kanal, and current City Commissioner Dan Ryan are all but guaranteed Council seats. The latest results show Ryan and Pirtle-Guiney were neck-and-neck in first-round counts, with just 73 votes separating the two. Pirtle-Guiney is a labor organizer and member of former Gov. Kate Brown's executive team. She also led the charge for Oregon Measure 114, which sought to limit gun magazine capacity and add a required permit for gun ownership. The measure passed but is currently held up in a court battle. Kanal served as the project manager for Portland's Police Accountability Commission and also serves on the city's Parks & Recreation Board.

District 3 saw Steve Novick, a former city commissioner, pull off a first-round win, guaranteeing his return to City Hall. He will be joined by elementary school teacher Tiffany Koyama Lane and nonprofit policy advocate Angelita Morillo, who were nearly tied with 19 percent of the overall vote in round one counts. Both Koyama Lane and Morillo ran on a progressive agenda, with Koyama Lane picking up an endorsement from Portland's Democratic Socialists of America (DSA). Candidates in District 3 will be up for election again in two years.

In District 4, Olivia Clark, a communications professional who previously worked in Gov. John Kitzhaber's office, secured a first-round win Thursday. She'll be one of three city councilors representing the district that includes Southwest Portland, including downtown, and small portions of Southeast Portland like Sellwood. Along with Clark, energy economist Mitch Green is a presumptive winner. Green emerged as easily the most progressive front-runner candidate in District 4, securing an endorsement from the Portland DSA. The third-place winner is appears to be political insider Eric Zimmerman, though first-round results show him with less than a percentage point lead over Eli Arnold and the race is still close.  Both candidates secured 11 percent of the overall vote in round one counts. Zimmerman previously worked in Mayor Ted Wheeler's office and currently works for Multnomah County Commissioner Julia Brim Edwards. Arnold is a Portland police officer. District 4 seats will be up for election again in two years.

In a closely watched federal race for Oregon's 5th Congressional District, Democrat Janelle Bynum secured a win over Republican incumbent Lori Chavez DeRemer, flipping the US House seat from red to blue. Other winners include incumbent Suzanne Bonamici in the 1st District and Maxine Dexter in the 3rd Congressional District.

By Friday, the vast majority of ballots were received and counted, though the Multnomah County Elections Office says it still has about 45,000 ballots to count. Overall voter turnout in Multnomah County is now hovering around 71 percent.

Results won’t be finalized until Dec. 2.

(Originally broadcast May 4, 2012)


Conversations about “hipster racism” are drawing heated commentary across the internet, including questions about who gets to use the n-word and why is there a dearth of black storylines in contemporary television programs – but what is “hipster racism?”


In conversation:
- Callie Crossley, host and executive editor of The Callie Crossley Show, WGBH Radio
- Kim McLarin, assistant professor of creative writing, Emerson College
- Phillip Martin, senior reporter, 89.7 WGBH Radio
- Peniel Joseph, professor of history and co-founder, Center for the Study of Race and Democracy, Tufts University
- Latoya Peterson, owner and editor of Racialicious.com

Brady chats with NYT columnist and Dartmouth political scientist Brendan Nyhan about this week's avalanche of political ads. Then, two seasoned primary watchers weigh in on the celebrities (and non-celebrities) candidates call upon in the primary's waning weeks. Finally, a public radio host who's interviewed hundreds of primary candidates shares her strategy to get them to open up. #FITN #2016 #Politics

Nipsey Hussle, a respected rapper who earned a Grammy nomination this year for his major-label debut, was fatally shot outside his clothing store, authorities said.

Marcus of All Trades posted a photo:

Ohio State has sold the name of a building before. Actually, several times before. But the naming rights to a job title? That seems a bit different.

Residents whose property was damaged by the Texas wildfires should contact their insurance company to file a claim as soon as possible.

The Texas Department of Insurance (TDI) reminds flood victims to document damage and file insurance claims right away.

If you experienced damage from Hurricane Beryl, contact your insurance company to start a claim.

Scam artists often follow a large storm or disaster. The Texas Department of Insurance (TDI) has tips to help recognize and avoid common contracting scams.

Blogger Kristina Ray was found dead in Sochi. Her body was found in a sewer. Kristina Ray (real name Kristina Kozhevnikova), the former holder of the title "Biggest Lips in Russia" went missing in Sochi. The woman stopped communicating with friends and family on September 28. Kristina's relatives told the police that she had suffered from drug addiction for a long time. A few days before her disappearance, Kristina found out that they wanted to put her in a rehab clinic. The police were able to find out that on the day of her disappearance, the woman went to get drugs. She was 35.

PPDS, the exclusive global provider of Philips professional displays, has announced that Telelogos software has been approved as the very first remote device management solution for the new Philips Tableaux range of Advanced Colour ePaper displays.

Shipster, a custom shipping integration platform, and Futura Retail Solutions, an advanced retail and warehouse management software, have announced a strategic partnership to target growing omni-channel retail markets.

Omni-ID, the developer of passive industrial radio frequency identification (RFID) tags, used by major global organisations for monitoring the location and identity of assets, has appointed Amir Mobayen as Chief Revenue Officer.

PPDS, the exclusive global provider of Philips Professional Displays and complementary hardware and software solutions, has announced the latest evolution of its multi-award-winning ePaper with Android SoC signage range, launching the new 13” Philips Tableaux 4150 at InfoComm 2024. 

As the peak festive sales season approaches, retailers face greater cybersecurity risk during the fourth quarter than any other time of year. Last year the average cost of a data breach jumped up 10% between 2023 and 2024. For retailers the cost has increased beyond the global annual average and sits at an 18% YoY increase ($2.96m).

You're driving out of a parking lot when you suddenly feel that you're having problems with the power steering. Learn about how to diagnose power steering problems in this article.

[Economy] :
The benchmark Korea Composite Stock Price Index shed three-point-48 points, or zero-point-14 percent, on Friday to close at two-thousand-561-point-15. The tech-heavy KOSDAQ gained nine-point-86 points, or one-point-34 percent, to close at 743-point-38.

[more...]

[Economy] :
South Korea’s benchmark Korea Composite Stock Price Index(KOSPI) slipped below the two-thousand-500 threshold on Tuesday for the first time since August’s “Black Monday.” The KOSPI dipped 49-point-09 points, or one-point-94 percent, on Tuesday to close at two-thousand-482-point-57. In the ...

[more...]

A reliable `in situ' method for wavefront sensing in the soft X-ray domain is reported, developed for the characterization of rotationally symmetric optical elements, like an ellipsoidal mirror shell. In a laboratory setup, the mirror sample is irradiated by an electron-excited (4.4 keV), micrometre-sized (∼2 µm) fluorescence source (carbon Kα, 277 eV). Substantially, the three-dimensional intensity distribution I(r) is recorded by a CCD camera (2048 × 512 pixels of 13.5 µm) at two positions along the optical axis, symmetrically displaced by ±21–25% from the focus. The transport-of-intensity equation is interpreted in a geometrical sense from plane to plane and implemented as a ray tracing code, to retrieve the phase Φ(r) from the radial intensity gradient on a sub-pixel scale. For reasons of statistical reliability, five intra-/extra-focal CCD image pairs are evaluated and averaged to an annular two-dimensional map of the wavefront error {cal W}. In units of the test wavelength (C Kα), an r.m.s. value sigma_{cal{W}} = ±10.9λ0 and a peak-to-valley amplitude of ±31.3λ0 are obtained. By means of the wavefront, the focus is first reconstructed with a result for its diameter of 38.4 µm, close to the direct experimental observation of 39.4 µm (FWHM). Secondly, figure and slope errors of the ellipsoid are characterized with an average of ±1.14 µm and ±8.8 arcsec (r.m.s.), respectively, the latter in reasonable agreement with the measured focal intensity distribution. The findings enable, amongst others, the precise alignment of axisymmetric X-ray mirrors or the design of a wavefront corrector for high-resolution X-ray science.

Reconstructions from the Daynès Studio in Paris depict a male Neanderthal (right) face to face with a human, Homo sapiens.; Credit: /Science Source

It's something that many of us reckon with: the sense that we're not quite as sharp as we once were.

I recently turned 42. Having lost my grandfather to Alzheimer's, and with my mom suffering from a similar neurodegenerative disease, I'm very aware of what pathologies might lurk beneath my cranium.

In the absence of a cure for Alzheimer's and other forms of dementia, the most important interventions for upholding brain function are preventive — those that help maintain our most marvelous, mysterious organ.

Based on the science, I take fish oil and broil salmon. I exercise. I try to challenge my cortex to the unfamiliar.

As I wrote my recent book, A History of the Human Brain, which recounts the evolutionary tale of how our brain got here, I began to realize that so many of the same influences that shaped our brain evolution in the first place reflect the very measures we use to preserve our cognitive function today.

Being social, and highly communicative. Exploring creative pursuits. Eating a varied, omnivorous diet low in processed foods. Being physically active.

These traits and behaviors help retrace our past, and, I believe, were instrumental in why we remain on the planet today.

And they all were, at least in part, enabled by our brain.

Social smart alecks finish first

The human saga is riddled with extinctions.

By "human," I don't just mean Homo sapiens, the species we belong to, but any member of the genus Homo. We've gotten used to being the only human species on Earth, but in our not so distant past — probably a few hundred thousand years ago – there were at least nine of us running around.

There was Homo habilis, or the "handy man." And Homo erectus, the first "pitcher." The Denisovans roamed Asia, while the more well-known Neanderthals spread throughout Europe.

But with the exception of Homo sapiens, they're all gone. And there's a good chance it was our fault.

Humans were never the fastest lot on the African plains, and far from the strongest. Cheetahs, leopards and lions held those distinctions. In our lineage, natural selection instead favored wits and wiliness.

Plenty of us became cat food, but those with a slight cognitive edge — especially Homo sapiens — lived on. In our ilk, smarts overcame strength and speed in enabling survival.

Ecology, climate, location and just sheer luck would've played important roles in who persisted or perished as well, as they do for most living beings. But the evolutionary pressure for more complex mental abilities would lead to a massive expansion in our brain's size and neurocircuitry that is surely the paramount reason we dominate the planet like no other species ever has.

Much of this "success," if you can call it that, was due to our social lives.

Primates are communal creatures. Our close monkey and ape cousins are incredibly interactive, grooming each other for hours a day to maintain bonds and relationships. Throw in a few hoots and hollers and you have a pretty complex community of communicating simians.

An active social life is now a known preserver of brain function.

Research shows that social isolation worsens cognitive decline (not to mention mental health, as many of us experienced this past year). Larger social networks and regular social activities are associated with mental preservation and slowed dementia progression.

Entwined in this new social life was an evolutionary pressure that favored innovation. Our eventual ability to generate completely novel thoughts and ideas, and to share those ideas, came to define our genus.

As we hunted and foraged together, and honed stones into hand axes, there was a collective creativity at work that gave us better weapons and tools that enabled more effective food sourcing, and, later, butchering and fire. Effectively sharing these innovations with our peers allowed information to spread faster than ever before - a seed for the larger communities and civilizations to come.

Challenging ourselves to new pursuits and mastering new skills can not only impress peers and ingratiate us to our group, but literally help preserve our brain. New hobbies. New conversations. Learning the banjo. Even playing certain video games and simply driving a new route home from work each day, as neuroscientist David Eagleman does, can keep our function high.

Whether it's honing ancient stone or taking up Sudoku, any pursuit novel and mentally challenging may help keep the neural circuits firing.

We really are what we eat

All the while, as we hunted and crafted in new and communal ways, we had to eat. And we did so with an uniquely adventurous palette.

Homo sapiens is among the most omnivorous species on the planet. Within reason we eat just about anything. Whether it's leaves, meat, fungus, or fruit, we don't discriminate. At some point, one of us even thought it might be a good idea to try the glistening, grey blobs that are oysters - and shellfish are, it turns out, among the healthiest foods for our brain.

The varied human diet is an integral part of our story. As was the near constant physicality required to source it.

On multiple occasions over the past 1 to 2 million years climate changes dried out the African landscape, forcing our ancestors out of the lush forest onto the dangerous, wide-open grasslands. As evolution pressured us to create and commune to help us survive, a diverse diet also supported our eventual global takeover.

Our arboreal past left us forever craving the dangling fruits of the forest, a supreme source of high-calorie sugars that ensured survival. Back then we didn't live long enough to suffer from Type 2 diabetes: if you encountered sweets, you ate them. And today we're stuck with a taste for cookies and candy that, given our longer lifespans, can take its toll on the body and brain.

But humans were just as amenable to dining on the bulbs, rhizomes and tubers of the savanna, especially once fire came along. We eventually became adept scavengers of meat and marrow, the spoils left behind by the big cats, who preferred more nutritive organ meat.

As our whittling improved we developed spears, and learned to trap and hunt the beasts of the plains ourselves. There is also evidence that we learned to access shellfish beds along the African coast and incorporate brain-healthy seafood into our diet.

Studying the health effects of the modern diet is tricky. Dietary studies are notoriously dubious, and often involve countless lifestyle variables that are hard to untangle.

Take blueberries. Multiple studies have linked their consumption with improved brain health. But, presumably, the berry-prone among us are also more likely to eat healthy all around, exercise, and make it to level 5 on their meditation app.

Which is why so many researchers, nutritionists, and nutritional psychiatrists now focus on dietary patterns, like those akin to Mediterranean culinary customs, rather than specific ingredients. Adhering to a Mediterranean diet is linked with preserved cognition; and multiple randomized-controlled trials suggest doing so can lower depression risk.

A similar diversity in our ancestral diet helped early humans endure an ever-shifting climate and times of scarcity. We evolved to subsist and thrive on a wide range of foods, in part because our clever brains allowed us access to them. In turn, a similarly-varied diet (minus submitting to our innate sugar craving of course) is among the best strategies to maintain brain health.

All of our hunting, and foraging, and running away from predators would have required intense physical exertion. This was certainly not unique to humans, but we can't ignore the fact that regular exercise is another effective means of preserving brain health.

Being active improves performance on mental tasks, and may help us better form memories. Long before the Peletons sold out, our brains relied on both mental and physical activity.

But overwhelmingly the evidence points to embracing a collection of lifestyle factors to keep our brain healthy, none of which existed in a Darwinian vacuum.

Finding food was as social an endeavor as it was mental and physical. Our creative brains harnessed information; gossiping, innovating, and cooking our spoils around the campfire.

Researchers are beginning to piece together the complex pathology behind the inevitable decline of the human brain, and despite a parade of failed clinical trials in dementia, there should be promising treatments ahead.

Until then, in thinking about preserving the conscious experience of our world and relationships — and living our longest, happiest lives — look to our past.

Bret Stetka is a writer based in New York and an editorial director at Medscape. His work has appeared in Wired, Scientific American, and on The Atlantic.com. His new book, A History of the Human Brain, is out from Timber/Workman Press. He's also on Twitter: @BretStetka.

This content is from Southern California Public Radio. View the original story at SCPR.org.

In this photo taken on February 10, 2020 a 'love kit' is seen on the bed in a room at the Dragonfly hotel in Mumbai.; Credit: PUNIT PARANJPE/AFP via Getty Images

A new survey shows that in the era of widespread vaccine availability, American couples are more satisfied in their relationships -- and some are even getting more experimental than they have been.

Led by Indiana University Kinsey Institute researcher Justin Lehmiller in collaboration with the website Lovehoney, which describes itself as “global sexual happiness experts,” the report looked at responses from 2,000 U.S. adults age 18-45, including an oversample of 200 who identified as LGBTQ, and among the major findings of the survey were that more than half (51 percent) of respondents said their sexual interests had changed during the pandemic, and many of those said they’d started trying things they hadn’t before. It also found that 44 percent of people surveyed said they were communicating better with their partner, and among singles surveyed 52 percent say they’re less interested in casual sex and more than a third of them said they weren’t interested in having sex on the first date.

Today on AirTalk, we’ll talk with Professor Lehmiller about the survey, its findings and how the pandemic impacted Americans’ views on relationships and sex.

Guest: 

Justin Lehmiller, social psychologist and research fellow at Indiana University’s Kinsey Institute who conducted the “Summer of Love” survey; author of “Tell Me What You Want: The Science of Sexual Desire and How It Can Help You Improve Your Sex Life” (Hachette Go, July 2020); host of the “Sex and Psychology” podcast; he tweets @JustinLehmiller

This content is from Southern California Public Radio. View the original story at SCPR.org.

The Pathfinding Partnerships Award from CO-LABS recognizes impactful, collaborative research projects organized by four or more research entities, including federal labs, in Colorado. This year, the Wildfire Research (WiRē) team received this award for their support of evidence-based community wildfire education to help communities live with wildfire. 

What if the August 23 earth tremors had been closer or stronger? Would you know what to do? Here are some tips from Catawba County Emergency Services.

High schools that successfully engage students in learning have many things in common.

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine today announced the recipients of its 2018 Science Policy Fellowships.

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine today announced the recipients of its 2018 Early-Career Research Fellowships.

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine is now accepting applications for its Early-Career Research Fellowships and Science Policy Fellowships for 2019.

Renewed interest in exploration of the moon has the potential to benefit lunar science greatly and could evolve into a program facilitated by partnerships between commercial companies and NASA’s Science Mission Directorate (SMD), say companion reports by the National Academies of Sciences, Engineering, and Medicine.

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine announced today the recipients of its 2019 Early-Career Research Fellowships.

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine today announced the 20 recipients of its 2020 Early-Career Research Fellowships.

The COVID-19 pandemic has presented a relatively rare situation in which the entire globe is grappling with the same crisis at the same time, albeit with widely varying approaches, resource levels, and political structures.

Keep your cool, arm yourself with the right knowledge, and other tips for staying unshaken by fraudsters’ scare tactics

The world needs more cybersecurity professionals – here are three great ways to give you an ‘in’ to the ever-growing and rewarding security industry

You may not always stop your personal information from ending up in the internet’s dark recesses, but you can take steps to protect yourself from criminals looking to exploit it

New data apps tracking firm Sensor Tower indicates the hype has died down and Threads has seen a 20% decrease in active users and a 50% reduction in time spent on the app, from 20 minutes to 10 minutes.

BT decided to showcase its technology by hosting a virtual media summit for AMEA and we knew that we could save money and invite more people if we made it virtual.

Nvidia CEO Jensen Huang has requested SK Hynix to expedite the delivery of HBM4 chips by six months. This request, revealed by SK Group Chairman Chey Tae-won, highlights the surging demand for Nvidia's AI accelerators, which heavily rely on HBM chips.

Semiconductor design global capability centres (GCC) account for approximately 4 per cent of India's total GCCs, with a growth rate of about 7 per cent in the last two decades.

Samsung's FOWLP-HPB cooling tech for Exynos 2500 chipsets, set for Q4 2024, will enhance performance, modeled in Galaxy S25. Galaxy Z Fold 6, Z Flip 6 launching at Glaaxy Unpacked with Snapdragon 8 Gen 3, 4000mAh battery, 50MP sensor, and IP48 durability rating aims to combat Exynos 2400 throttling, offering better battery life and consistent performance.

The more plant personnel who participate in your facility’s food safety audit, the better. These educational experiences allow your staff to engage with the audit process and improve their food safety knowledge.

The chips use high-quality, free of palm oil chocolate, ensuring an ethical snacking experience.