Tabu and Aishwarya Rai Bachchan's movie, Kandukondain Kandukondain completed 20 years today and this movie besides being based on Jane Austen's Sense and Sensibility was also a fashion treat. Tabu and Aishwarya Rai looked gorgeous on-screen and gave us

With the summer season around the corner, India is already feeling the heat. And according to reports from researchers, the summer will bring additional discomfort - due to the COVID-19 pandemic. There were some claims which said that the coronavirus may

The summer season is around the corner and we are all already feeling the heat. According to climate scientists, the temperature is most likely to rise in the coming months and along with the heat comes heat stress or body heat,

Sonam Kapoor Ahuja went for traditional red on her wedding. The diva celebrates her second wedding anniversary today and we can't stop admiring the lehenga that she wore on her wedding. It was a gorgeous lehenga but her red-hued traditional

World Red Cross Day is observed every year on 8 May to mark the birth anniversary of Henry Dunant, the founder of the Red Cross and International Committee of the Red Cross (ICRC). He was born on 8 May 1828 and

Lewis Library - ML3917.A78 M35 2018

Will discuss various issues, including credit off-take

Drug major Dr Reddy’s Laboratories is recalling 1,752 bottles of generic heartburn medicine in the US after the American health regulator found qual

At the first sign of trouble, one should exit credit risk funds: Arvind Chari, Head - Fixed Income and Alternatives, Quantum Advisors

Creates special bureau for liquor, sand

Pain ahead for motor and health business, but focus on profitable segments and market share gains to aid earnings

Pharma major Dr Reddy’s Laboratories Ltd has initiated recall of 1m752 bottles of generic Esomeprazole Magnesium delayed release capsules in the US.A

Many companies, including Samsung, Panasonic, Sony, Whirlpool of India and BSH Home appliances, in the country are getting enquiries from people confined in their homes about such products.

ICICI Bank stock has corrected 37 per cent in three months. But investors should not rush into it

It is said to be the first road accident in Karur district after the lockdown was announced.

News reports suggest that a total of 150 soldiers were involved in the face-off that allegedly took place a few days back.

1. NRL 2020: Erin Molan condemns ‘incredibly dangerous’ Holocaust Instagram post, Bryce Cartwright wife  NEWS.com.au
2. Gold Coast Titans anti-vaccination: Doctor’s warning over flu jab after NRL players stood down  Gold Coast Bulletin
3. NRL 2020, news: Bryce Cartwright’s wife hits out in flu shot storm, Instagram post, anti-vaccination players react  NEWS.com.au
4. NRL: Anti-vaxxers stood down as vaccination debate rages on  news.com.au
5. 'It's a team sport boys': Cronulla skipper Wade Graham calls out anti-vaxxers  Wide World of Sports
6. View Full coverage on Google News

1. The COVIDSafe app – What we know and questions that remain unanswered - Coronavirus (COVID-19) - Australia  Mondaq News Alerts
2. Readers respond to the COVIDSafe app's launch  Sydney Morning Herald
3. COVIDSafe app downloads shoot past five million  Sky News Australia
4. UK contact tracing app source code shared as researchers seek to solve mystery  9to5Mac
5. Lack of honesty on virus app is a problem  9News
6. View Full coverage on Google News

1. This Red Dead Redemption II Mod Lets You Ride A Giant Cougar  Kotaku Australia
2. Red Dead Redemption 2 hog riding mod is even better than it sounds  GamesRadar+ AU
3. Ride tall, handsome hogs in this necessary RDR2 mod  PC Gamer
4. Red Dead Online: How to Enable Autopilot | Screen Rant  Screen Rant
5. This Red Dead Redemption 2 Theory Explains Dutch's Behavior | CBR  CBR - Comic Book Resources
6. View Full coverage on Google News

1. Ten arrested and police officer injured at protest against Victoria’s Covid-19 lockdown laws  The Guardian
2. Hundreds of anti-vaxxers clash with police during protest in Melbourne's CBD  Daily Mail
3. Coronavirus: Anti-lockdown protesters clash with police in Melbourne  NEWS.com.au
4. Ten arrested, police officer injured in anti-lockdown protest  The Age
5. Coronavirus Australia updates: anti-lockdown protest in Melbourne as NSW and WA set to ease Covid-19 restrictions – as it happened  The Guardian
6. View Full coverage on Google News

Sara is a journalist who wholeheartedly throws herself into her work as a journalist for a newspaper in Juarez. Mexico however is a country where journalists sometimes do their work under threats to themselves and their families and going to the police is not always a good idea. Sara soon finds that if she wants to pursue this particular story she could be putting the lives of herself, her younger brother Emiiano and their mother in danger.

Emiliano is a soccer star at his high school and in addition to this he is also a member of a school group called Jiparis who do hikes through the desert in order to build character in the young men, some of whom were involved in unsavory activities before joining the group.

One part of the Jipari pledge goes , "I will be honest with myself and others". This is easier said than done especially in a city like Juarez. One of the characters tells Emiliano, "everything is a spiderweb" and the speed with which he is enveloped in said web is astounding. Emiliano tells himself that he wants to help his family and friends out but are those his real reasons? Like any teen he wants to be seen as cool and there is also the small matter of a girl he wants to impress.

The first part of the book is told from each character's viewpoint and the author weaves the tale together in a very credible way showing how circumstances

Make no mistake, Disappeared is not a peaches and cream, hunky dory teen novel. It is a gritty and very realistic novel with a ripped from the headlines quality to it. The city of Juarez and the violence there doesn't dominate the headlines as it did a few years ago, but Stork's novel is a timely reminder that evil still exists and that it takes many people working in tandem to defeat it.

1. DFL-preses na coronagevallen bij Dresden: "Geen reden om te twijfelen"  sporza.be
2. Volledige ploeg Dynamo Dresden moet één week voor herstart Duitse competitie in quarantaine: “Kunnen 14 dagen niet spelen”  Het Laatste Nieuws
3. Al 3 spelers besmet: "Niet twijfelen aan de voortzetting 2. Bundesliga"  VoetbalNieuws.be
4. 2 extra besmettingen bij Dresden: team in quarantaine en duel met Hannover uitgesteld  sporza.be
5. Geen twijfels over hervatting Duits voetbal na nieuwe besmettingen: “Vanaf het begin gezegd dat we hierop voorbereid zijn”  Het Laatste Nieuws
6. Hele verhaal bekijken via Google Nieuws

Me oh my, Mr. Fox Friend! What a lovely stare you've got there!

Princeton University Professor of Mathematics John Mather, remembered as a "great mathematician" with a reserved and pleasant demeanor, died Jan. 28 of complications from prostate cancer at his home in Princeton. He was 74.

Since the Middle Ages, alchemists have sought to transmute elements, the most famous example being the long quest to turn lead into gold. Now, Princeton University theorists have proposed a different approach to this ancient ambition — just make one material behave like another. The researchers demonstrate that any two systems can be made to look alike, even if just for the smallest fraction of a second.

WASHINGTON (April 28, 2020) — Today, the U.S.

Environmental News FOR IMMEDIATE RELEASE

Environmental News FOR IMMEDIATE RELEASE

BOSTON – The US Environmental Protection Agency (EPA) is awarding seven local New England organizations with recognition for their work keeping wasted food out of landfills and incinerators and putting it to better use.

DENVER (April 23, 2020)) - Today, the U.S. Environmental Protection Agency (EPA) recognized Sprouts Farmers Market Store #305 in Aurora, CO and Sprouts Farmers Market Store #325 in Englewood, CO, with 2019 Food Recovery Challenge Regional Awards.

DALLAS – (April 23, 2020)  The U.S. Environmental Protection Agency (EPA) announced the 2019 winners of the national WasteWise awards.

Environmental News FOR IMMEDIATE RELEASE

(PHILADELPHIA, April 28, 2020) – The U.S. Environmental Protection Agency (EPA) recognized Towson University in Maryland today with a 2019 Food Recovery Challenge Regional Award.

Environmental News FOR IMMEDIATE RELEASE

Edwin Cabrera, a father of two, was unlocking his e-bike after dropping off a pizza on Fort George Hill near Fairview Ave. on May 3 when two suspects jumped out of the shadows and attacked him around 9 p.m.

There was certainly was stress in the air when health and economic consqeuences of COVID-19 bore down on Brooklyn and the rest of America. But as these pressures grew, constructive hearts and minds prevailed at the BKLYN Commons (BKC) shared workspace operation at 495 Flatbush Ave., in the Prospect-Lefferts Gardens area, which creatively and passionately morphed to adapt to the new normal.

Surrey director of cricket Alec Stewart has reluctantly accepted there could yet be a long-term good for the county game if it is wiped out in 2020.

Two aboriginal scarred trees, photographed today near Stanhope in Victoria.

The following article, NYC Nurse Steals Credit Card From 70-Yr-Old Dying COVID-19 Patient On Ventilator, was first published on 100PercentFedUp.com.

"She is a despicable human being"

Continue reading: NYC Nurse Steals Credit Card From 70-Yr-Old Dying COVID-19 Patient On Ventilator ...

6 March 2014

Lethal infections by strains of the highly-pathogenic avian influenza virus (HPAIV) H5N1 pose serious threats to both the poultry industry and public health worldwide. A lack of confirmed HPAIV epitopes recognized by cytotoxic T lymphocytes (CTLs) has hindered the utilization of CD8+ T-cell–mediated immunity and has precluded the development of effectively diversified epitope-based vaccination approaches. In particular, an HPAIV H5N1 CTL-recognized epitope based on the peptide MHC-I–β2m (pMHC-I) complex has not yet been designed. Here, screening a collection of selected peptides of several HPAIV strains against a specific pathogen-free pMHC-I (pBF2*1501), we identified a highly-conserved HPAIV H5N1 CTL epitope, named HPAIV–PA123–130. We determined the structure of the BF2*1501–PA123–130 complex at 2.1 Å resolution to elucidate the molecular mechanisms of a preferential presentation of the highly-conserved PA123–130 epitope in the chicken B15 lineage. Conformational characteristics of the PA123–130 epitope with a protruding Tyr-7 residue indicated that this epitope has great potential to be recognized by specific TCRs. Moreover, significantly increased numbers of CD8+ T cells specific for the HPAIV–PA123–130 epitope in peptide-immunized chickens indicated that a repertoire of CD8+ T cells can specifically respond to this epitope. We anticipate that the identification and structural characterization of the PA123–130 epitope reported here could enable further studies of CTL immunity against HPAIV H5N1. Such studies may aid in the development of vaccine development strategies using well-conserved internal viral antigens in chickens.

Protease-activated receptor 2 (PAR-2) is activated by secreted proteases from immune cells or fungi. PAR-2 is normally expressed basolaterally in differentiated nasal ciliated cells. We hypothesized that epithelial remodeling during diseases characterized by cilial loss and squamous metaplasia may alter PAR-2 polarization. Here, using a fluorescent arrestin assay, we confirmed that the common fungal airway pathogen Aspergillus fumigatus activates heterologously-expressed PAR-2. Endogenous PAR-2 activation in submerged airway RPMI 2650 or NCI–H520 squamous cells increased intracellular calcium levels and granulocyte macrophage–colony-stimulating factor, tumor necrosis factor α, and interleukin (IL)-6 secretion. RPMI 2650 cells cultured at an air–liquid interface (ALI) responded to apically or basolaterally applied PAR-2 agonists. However, well-differentiated primary nasal epithelial ALIs responded only to basolateral PAR-2 stimulation, indicated by calcium elevation, increased cilia beat frequency, and increased fluid and cytokine secretion. We exposed primary cells to disease-related modifiers that alter epithelial morphology, including IL-13, cigarette smoke condensate, and retinoic acid deficiency, at concentrations and times that altered epithelial morphology without causing breakdown of the epithelial barrier to model early disease states. These altered primary cultures responded to both apical and basolateral PAR-2 stimulation. Imaging nasal polyps and control middle turbinate explants, we found that nasal polyps, but not turbinates, exhibit apical calcium responses to PAR-2 stimulation. However, isolated ciliated cells from both polyps and turbinates maintained basolateral PAR-2 polarization, suggesting that the calcium responses originated from nonciliated cells. Altered PAR-2 polarization in disease-remodeled epithelia may enhance apical responses and increase sensitivity to inhaled proteases.

This final report summarizes and reflects upon the key findings of the Improving EU and U.S. Immigration Systems: Learning from Experience comparative research project undertaken by MPI and the European University Institute through a grant from the European Commission.

THE LAST two months have been two of the worst in the life of former national netball star Nichala Gibson. She lives in New York City, the epicentre for the COVID-19 virus in the United States. Gibson and her sister suffered, then recovered from...

A Manchester corporal is now on sick leave after receiving several blows to his face allegedly by a woman police inspector at work yesterday. It is reported that the incident happened in the guard room of the Mandeville Police Station.