Says troubled marriage inspired her to become a feminist.

Nearly everyone on Earth is familiar with corn. Literally. Around the world, each person eats an average of 70 pounds of the grain each year, with even more grown for animal feed and biofuel.

The platforms, providers, and infrastructures which together make up the contemporary Internet play an increasingly central role in the business of governing human societies. Although the software engineers, administrators, business professionals, and other staff working at these organisations may not have the institutional powers of state organisations such as law enforcement or the civil service, … Continue reading Three Paper Thursday: The role of intermediaries, platforms, and infrastructures in governing crime and abuse →

It's like three buses showing up at once carrying $8bn

India’s largest mobile carrier, Jio, has just scored a third new investor in three weeks!…

IBM today announced that IBM Watson Internet of Things (IoT) has been named a Leader in the IDC MarketScape: Worldwide IoT Platforms 2017 Vendor Assessment (Doc # US42033517, July 2017). The report highlights IBM’s Watson IoT Platform on IBM Cloud, which today is being used by thousands of clients and partners across six continents including BMW, KONE, HARMAN and more.

IBM announced today that Acrow, one of Australia’s leading suppliers of scaffolding and formwork for the construction industry, has selected IBM and IT Easy , to implement a total infrastructure refresh built around IBM Cloud, mobile, and network technology.

IBM today announced that M-Industry, one of the world’s largest private label consumer goods company and subsidiary of Switzerland’s largest retailer and supermarket chain, Migros Group, has launched a new IBM designed mobile offering to transform how product promoters work.

IBM today announced sweeping advances in its all-flash storage solutions and software to significantly drive down the costs of data and extend its solutions for hybrid and private cloud environments.

6月13日(土)開催バースデーライブ！「KIMERU Live 2020 Halloween Party Birthday」の告知動画が完成しました！！ ライブ様子を見るだけでうずうずしますね!チケットをまだお持ちでない方に朗報です♪本日より yahoo!チケット先行 の受付開始★受付期間は4月20日(月)まで！そして、現在 アニメイト特別先行 も受付中！こちらは1週間限定先行で購入者には特典で"サイン入り仮装衣装ブロマイド”が会場にて貰えます!!ライブ当日に着用する仮装衣装のブロマイドに直筆サイン！4月12日までの限定先行なのでこの機会に今すぐお申し込みを！ ハロウィン×KIMERUバースデーのライブ！KIMERUは仮装衣装でのライブ♪ ハロウィンライブは2012年以来のようで、なんと8年ぶり!!前回はドラキュラや早着替えで魔女風仮装をしてました♪今回はどんな衣装で登場するのかお楽しみ!! 6月はみんなで楽しい時間を過ごしましょう★===================KIMERU Live 2020 Halloween Party Birthday◇日程2020年6月13日(土)　OPEN 12:30/START 13:00◇会場青山RizM◇チケット ※別途ドリンク代・スタンディング　 5,500円◇チケットお申込み <先行発売> ※抽選●アニメイト特別先行 <受付中！>申込URL:https://www.animate-onlineshop.jp/pn/pd/1776119/受付期間：4月4日（土）10:00～4月12日（日）23:59当落入金：4月15日（水）～4月19日（日）23:59特典：サイン入り仮装衣装ブロマイド●Yahoo!チケット先行 <受付中！>申込URL：https://ticket.yahoo.co.jp/tour/00004935/受付期間：2020年4月7日(火)15:00～4月20日(月)23:59当落入金：2020年4月25日(土)15:00～4月29日(水)23:59 ===============続きをみる

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6月13日(土)開催のバースデーライブ！「KIMERU Live 2020 Halloween Party Birthday」のyahoo!チケット先行の受付が本日4月20日(月) 23:59まで！まだチケットをお持ちでない方はお申込みを急げ！ 「KIMERU Live 2020 Halloween Party Birthday」◇日程2020年6月13日(土) OPEN 12:30/START 13:00◇会場青山RizM ◇チケット　※別途ドリンク代・スタンディング　 5,500円●Yahoo!チケット先行 <受付中！>申込URL：https://ticket.yahoo続きをみる

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New forms of living, new ideas for cohabitation, new architecture: For the Social Design Award, we are looking for the best projects and ideas for neighborhood-oriented living models. The winner will receive 2,500 euros.

We study the trade-offs faced by Internet Service Providers (ISPs) that serve as platforms through which consumers access both television and internet services. As online streaming video improves, these providers may respond by attempting to steer consumers away from streaming video toward their own TV services, or by attempting to capture surplus from this improved internet content. We augment the standard mixed bundling model to demonstrate the trade-offs the ISP faces when dealing with streaming video, and we show how these trade-offs change with the pricing options available to the ISP. Next, we use unique household-level panel data and the introduction of usage-based pricing (UBP) in a subset of markets to measure consumers' responses and to evaluate quantitatively the ISP's trade-offs. We find that the introduction of UBP led consumers to upgrade their internet service plans and lower overall internet usage. Our findings suggest that while steering consumers towards TV services is possible, it is likely costly for the ISP and therefore unlikely to be profitable. This is especially true if the ISP can offer rich pricing menus that allow it to capture some of the surplus generated by a better internet service. The results suggest that policies like UBP can increase ISPs' incentive to maintain open access to new internet content.

Two men accused of violent crimes were freed without bail from Brooklyn Criminal Court on Thursday amid growing concern about the state's new bail reform laws.

NYPD officers made fewer than 150 arrests in city schools between Oct. 1 and Dec. 31, 2019 — about half the number of arrests cops made during the same months last year.

Fisher helped implement the reforms that rebuilt the Los Angeles Police Department after the Rodney G. King scandal and the 1992 riots.

The Brombergs, who immigrated to Israel from São Paulo, Brazil in 2018, play and sing Leonard Cohen’s enduring classic song in English and Hebrew.

UNIVERSAL CREDIT claims have surged in recent weeks, as Britons have begun to feel the impact of the coronavirus crisis. How do earnings affect payments?

UNIVERSAL CREDIT claims have surged in recent weeks, as Britons have begun to feel the impact of the coronavirus crisis. How do earnings affect payments?

As Dallara's Stefano DePonti saw his parent company begin to manufacture parts for ventilators back in Italy, he knew the IndyCar shop needed to step in to help fight COVID-19.

Kevin Jones performs his song, "I Can See The Stars" before the Tom Odell show at the Moroccan Lounge in Los Angeles.

Carmel and IU grad Sage Steele will co-host and star athletes like Drew Brees and Venus Williams will announce winners during the online broadcast.

The owner of FoxGardin in Fortville transformed himself into Joe Exotic to help his workers.

The owner of FoxGardin in Fortville transformed himself into Joe Exotic to help his workers.

Carmel and IU grad Sage Steele will co-host and star athletes like Drew Brees and Venus Williams will announce winners during the online broadcast.

What is a (digital) form? In a broader sense of the meaning, a form, is an interface that collects through interactions, the required information, in a logical, meaningful way, and then passes it to at least one third party entity. Sounds complicated, right?

HNF4α is a nuclear receptor produced as 12 isoforms from two promoters by alternative splicing. To characterize the transcriptional capacities of all 12 HNF4α isoforms, stable lines expressing each isoform were generated. The entire transcriptome associated with each isoform was analyzed as well as their respective interacting proteome. Major differences were noted in the transcriptional function of these isoforms. The α1 and α2 isoforms were the strongest regulators of gene expression whereas the α3 isoform exhibited significantly reduced activity. The α4, α5, and α6 isoforms, which use an alternative first exon, were characterized for the first time, and showed a greatly reduced transcriptional potential with an inability to recognize the consensus response element of HNF4α. Several transcription factors and coregulators were identified as potential specific partners for certain HNF4α isoforms. An analysis integrating the vast amount of omics data enabled the identification of transcriptional regulatory mechanisms specific to certain HNF4α isoforms, hence demonstrating the importance of considering all isoforms given their seemingly diverse functions.

A. Knightly and C. Li
Memoirs of the AMS 224 (2012).
Abstract, references and article information

euromicron AG, a medium-sized technology group and specialist for the digital support of business processes through secure infrastructures, is pooling its digital expertise at KORAMIS GmbH, the group subsidiary that specializes in cyber security and automation. With focus on digital platforms and services KORAMIS’ portfolio will also cover the areas Smart IoT, Smart Building as well as Data Management in the future. For this step the management of KORAMIS GmbH was extended by Andreas Schmidt.

Pietro Mercuri and René Schoof
Math. Comp. 89 (2020), 1969-1991.
Abstract, references and article information

Maciej Bocheński and Aleksy Tralle
Proc. Amer. Math. Soc. 148 (2020), 2743-2744.
Abstract, references and article information

(Institute for Operations Research and the Management Sciences) New research to be published in the INFORMS journal Management Science has found popular rideshare platforms exhibit racial and other biases that penalize under-represented minorities and others seeking to use their services.

Élie Lambert
May 1, 2020; 19:808-827
Research

A data-driven method for respiratory gating in PET has recently been commercially developed. We sought to compare the performance of the algorithm to an external, device-based system for oncological [¹⁸F]-FDG PET/CT imaging. Methods: 144 whole-body [¹⁸F]-FDG PET/CT examinations were acquired using a Discovery D690 or D710 PET/CT scanner (GE Healthcare), with a respiratory gating waveform recorded by an external, device based respiratory gating system. In each examination, two of the bed positions covering the liver and lung bases were acquired with duration of 6 minutes. Quiescent period gating retaining ~50% of coincidences was then able to produce images with an effective duration of 3 minutes for these two bed positions, matching the other bed positions. For each exam, 4 reconstructions were performed and compared: data driven gating (DDG-retro), external device-based gating (RPM Gated), no gating but using only the first 3 minutes of data (Ungated Matched), and no gating retaining all coincidences (Ungated Full). Lesions in the images were quantified and image quality was scored by a radiologist, blinded to the method of data processing. Results: The use of DDG-retro was found to increase SUVmax and to decrease the threshold-defined lesion volume in comparison to each of the other reconstruction options. Compared to RPM-gated, DDG-retro gave an average increase in SUV_max of 0.66 ± 0.1 g/mL (n=87, p<0.0005). Although results from the blinded image evaluation were most commonly equivalent, DDG-retro was preferred over RPM gated in 13% of exams while the opposite occurred in just 2% of exams. This was a significant preference for DDG-retro (p=0.008, n=121). Liver lesions were identified in 23 exams. Considering this subset of data, DDG-retro was ranked superior to Ungated Full in 6/23 (26%) of cases. Gated reconstruction using the external device failed in 16% of exams, while DDG-retro always provided a clinically acceptable image. Conclusion: In this clinical evaluation, the data driven respiratory gating technique provided superior performance as compared to the external device-based system. For the majority of exams the performance was equivalent, but data driven respiratory gating had superior performance in 13% of exams, leading to a significant preference overall.

Research Event

Event participants

Hon. Manuel José Nunes Júnior, Minister of State for Economic Coordination, Republic of Angola
Chair: Dr Alex Vines OBE, Managing Director, Ethics, Risk & Resilience; Director, Africa Programme, Chatham House

Research Event

Event participants

Tutu Alicante, Executive Director, EG Justice
Chair: Dr Alex Vines OBE, Managing Director, Ethics, Risk & Resilience; Director, Africa Programme, Chatham House

HNF4α is a nuclear receptor produced as 12 isoforms from two promoters by alternative splicing. To characterize the transcriptional capacities of all 12 HNF4α isoforms, stable lines expressing each isoform were generated. The entire transcriptome associated with each isoform was analyzed as well as their respective interacting proteome. Major differences were noted in the transcriptional function of these isoforms. The α1 and α2 isoforms were the strongest regulators of gene expression whereas the α3 isoform exhibited significantly reduced activity. The α4, α5, and α6 isoforms, which use an alternative first exon, were characterized for the first time, and showed a greatly reduced transcriptional potential with an inability to recognize the consensus response element of HNF4α. Several transcription factors and coregulators were identified as potential specific partners for certain HNF4α isoforms. An analysis integrating the vast amount of omics data enabled the identification of transcriptional regulatory mechanisms specific to certain HNF4α isoforms, hence demonstrating the importance of considering all isoforms given their seemingly diverse functions.

The millions of customers, the short deadline: how the public service's digital revolution will start.

The Orioles will honor late icon Frank Robinson during Grapefruit League play and will continue to do so throughout the season, with a patch on the sleeves of their uniforms. The patch features Robinson's No. 20 in orange against a black background.