Based on the OECD Analytical AMNE database, this paper analyses the domestic linkages of MNE affiliates in host economies in order to get better insights in the role MNEs play across countries.

25/04/2019-Global value chains (GVCs) have sharpened the interdependencies between trade and foreign direct investment (FDI). Using a novel micro-level dataset covering about 27 000 corporate relationships of 147 multinational enterprises (MNEs) in 13 sectors, new evidence is provided on how firms organise their production globally by combining trade with investment, and on a range of non-equity, contract-based partnerships.

This note identifies key findings and policy messages on how small and medium- sized enterprises (SMEs) in Southeast Asia can enhance integration in global value chains (GVCs). The list of policy messages in this note is not intended to be exhaustive but rather to provide a set of concrete and actionable measures.

This paper presents new descriptive evidence on value added generation and sourcing patterns of intermediate inputs for ship construction of major shipbuilding economies. The findings reveal that shipbuilding relies heavily on intermediate inputs as around 70-80% of the final output value of ship production is generated through supplier sectors.

Adopted in 2017, the OECD Due Diligence Guidance for Responsible Supply Chains in the Garment and Footwear Sector establishes a common understanding of due diligence in the sector to help companies meet the due diligence expectations laid out in the OECD Guidelines for Multinational Enterprises.

This paper describes the sources and methods used to produce the indicators in the OECD Trade in Employment database. These indicators were developed, as a complement to Trade in Value Added (TiVA) indicators, to provide broad insights into the impact of global value chains on labour markets.

Embracing new technologies that could enable drastic reductions in GHG emissions will be key to delivering low-emissions pathways for growth, but it is not always obvious what the big breakthroughs will look like. This report looks at how blockchain technology can be applied to support sustainable infrastructure investment that is aligned with climate change objectives.

What is the role of the private sector in greening the agro-food chain? This OECD/BIAC workshop will examine such issues as the role of new technologies in increasing productivity and reducing waste, as well as developing private-public partnerships.

This work addresses the role of global value chains (GVCs), workforce skills, ICT, innovation and industry structure in explaining employment levels of routine and non-routine occupations. The analysis encompasses 28 OECD countries over the period 2000-2011.

Analysis relying on a new OECD measure of the routine intensity of occupations shows the extent to which countries differ in the share of employment accounted for by routine jobs. It finds that while technological innovation is always associated with higher employment, ICTs correlates positively with employment in all occupations but not in high-routine jobs. Finally, offshoring need not hurt routine-intensive workers.

Despite major progress, Turkey still lags behind most comparable countries in terms of exported value added per capita. Its remarkable economic performance over the past 15 years has not been sufficiently backed by gains in export market shares, in particular when measured in value added terms.

Amid a growing debate over the benefits of globalisation, a new OECD report examines how the level and mix of skills in a country’s workforce can affect its chances of winning or losing from the globalised production chains that see workers dotted across different countries contributing to the design, manufacture and sale of a single product

The webinar will specifically be looking at recent developments in alternatives to long chain PFCs. Per- and polyfluorinated chemicals (PFCs) have been in use since the 1950s as ingredients or intermediates of surfactants and surface protectors for assorted industrial and consumer applications.

Considering the same, matter stands adjourned today. List after three weeks on a date to be fixed by the Registry.

JUDGE Comparing Assistant

With a joint announcement alongside CR7 Crunch Fitness, Ronaldo virtually guided fitness fanatics through seven workouts to help them stay in shape during the coronavirus lockdown.

New York, May 10 () Hollywood star Mark Wahlberg and Del Frisco's Double Eagle Steak House have joined hands to provide food to the city's healthcare workers and first responders.The Boston-based burger chain Wahlburgers - run by Wahlberg brothers, Mark, Donnie and Paul - has been shipping its patties to the steak house in Midtown to be cooked up, and the city's legendary firefighter themed sports bar Bravest have been helping deliver the meals."They wanted to honour the hospital workers and first responders," Gerard Fitzgerald, president of the Uniformed Firefighters Association, told Page Six.The meal deliveries started in Manhattan last week and end in Staten Island on Monday.The 'Jason Bourne' star said it was nice to help champion for someone else and give them the credit they deserve.

Hollywood star Mark Wahlberg and Del Frisco's Double Eagle Steak House have joined hands to provide food to the city's healthcare workers and first responders. The Boston-based burger chain Wahlburgers - run by Wahlberg brothers, Mark, Donnie and Paul - has been shipping its patties to the steak house in Midtown to be cooked up, and the city's legendary firefighter themed sports bar Bravest have been helping deliver the meals. "They wanted to honour the hospital workers and first responders," Gerard Fitzgerald, president of the Uniformed Firefighters Association, told Page Six. The meal deliveries started in Manhattan last week and end in Staten Island on Monday. The 'Jason Bourne' star said it was nice to help champion for someone else and give them the credit they deserve. "Not being able (to have our restaurants) fully operational these past several weeks has been heartbreaking for our entire organization. But that hasn't stopped our commitment to supporting the communities we ...

Archives, Room Use Only - PS3539.A14 C52 1915

How Lucknow's City Montessori Schools managed to offer comprehensive online education to its 57,000 students during the Covid-19 crisis

A method is presented for the automatic building of nucleotide chains into electron density which is fast enough to be used in interactive model-building software. Likely nucleotides lying in the vicinity of the current view are located and then grown into connected chains in a fraction of a second. When this development is combined with existing tools, assisted manual model building is as simple as or simpler than for proteins.

Chromatin is the complex assembly of nucleic acids and proteins that makes up the physiological form of the eukaryotic genome. The nucleosome is the fundamental repeating unit of chromatin, and is composed of ∼147 bp of DNA wrapped around a histone octamer formed by two copies of each core histone: H2A, H2B, H3 and H4. Prior to nucleosome assembly, and during histone eviction, histones are typically assembled into soluble H2A/H2B dimers and H3/H4 dimers and tetramers. A multitude of factors interact with soluble histone dimers and tetramers, including chaperones, importins, histone-modifying enzymes and chromatin-remodeling enzymes. It is still unclear how many of these proteins recognize soluble histones; therefore, there is a need for new structural tools to study non-nucleosomal histones. Here, a single-chain, tailless Xenopus H2A/H2B dimer was created by directly fusing the C-terminus of H2B to the N-terminus of H2A. It is shown that this construct (termed scH2BH2A) is readily expressed in bacteria and can be purified under non-denaturing conditions. A 1.31 Å resolution crystal structure of scH2BH2A shows that it adopts a conformation that is nearly identical to that of nucleosomal H2A/H2B. This new tool is likely to facilitate future structural studies of many H2A/H2B-interacting proteins.

Fragment-based molecular-replacement methods can solve a macromolecular structure quasi-ab initio. ARCIMBOLDO, using a common secondary-structure or tertiary-structure template or a library of folds, locates these with Phaser and reveals the rest of the structure by density modification and autotracing in SHELXE. The latter stage is challenging when dealing with diffraction data at lower resolution, low solvent content, high β-sheet composition or situations in which the initial fragments represent a low fraction of the total scattering or where their accuracy is low. SEQUENCE SLIDER aims to overcome these complications by extending the initial polyalanine fragment with side chains in a multisolution framework. Its use is illustrated on test cases and previously unknown structures. The selection and order of fragments to be extended follows the decrease in log-likelihood gain (LLG) calculated with Phaser upon the omission of each single fragment. When the starting substructure is derived from a remote homolog, sequence assignment to fragments is restricted by the original alignment. Otherwise, the secondary-structure prediction is matched to that found in fragments and traces. Sequence hypotheses are trialled in a brute-force approach through side-chain building and refinement. Scoring the refined models through their LLG in Phaser may allow discrimination of the correct sequence or filter the best partial structures for further density modification and autotracing. The default limits for the number of models to pursue are hardware dependent. In its most economic implementation, suitable for a single laptop, the main-chain trace is extended as polyserine rather than trialling models with different sequence assignments, which requires a grid or multicore machine. SEQUENCE SLIDER has been instrumental in solving two novel structures: that of MltC from 2.7 Å resolution data and that of a pneumococcal lipoprotein with 638 residues and 35% solvent content.

An online knowledge base on the alternate conformations adopted by main-chain and side-chain atoms in protein structures solved by X-ray crystallography is described.

A single-chain, tailless Xenopus laevis H2A/H2B dimer construct (scH2BH2A) was engineered by directly fusing the C-terminus of H2B to the N-terminus of H2A without an artificial linker sequence. A high-resolution crystal structure of scH2BH2A shows that it adopts a nearly identical fold to that of nucleosomal H2A/H2B and may be useful for future structural studies of many H2A/H2B-interacting proteins.

This study presents the crystal structure of a thiol variant of the human mitochondrial branched-chain aminotransferase protein. Human branched-chain aminotransferase (hBCAT) catalyzes the transamination of the branched-chain amino acids leucine, valine and isoleucine and α-ketoglutarate to their respective α-keto acids and glutamate. hBCAT activity is regulated by a CXXC center located approximately 10 Å from the active site. This redox-active center facilitates recycling between the reduced and oxidized states, representing hBCAT in its active and inactive forms, respectively. Site-directed mutagenesis of the redox sensor (Cys315) results in a significant loss of activity, with no loss of activity reported on the mutation of the resolving cysteine (Cys318), which allows the reversible formation of a disulfide bond between Cys315 and Cys318. The crystal structure of the oxidized form of the C318A variant was used to better understand the contributions of the individual cysteines and their oxidation states. The structure reveals the modified CXXC center in a conformation similar to that in the oxidized wild type, supporting the notion that its regulatory mechanism depends on switching the Cys315 side chain between active and inactive conformations. Moreover, the structure reveals conformational differences in the N-terminal and inter-domain region that may correlate with the inactivated state of the CXXC center.

Javad Fahanik-babaei, Bahareh Rezaee, Maryam Nazari, Nihad Torabi, Reza Saghiri, Remy Sauve, and Afsaneh Eliassi

We have determined the electropharmacological properties of a new potassium channel from brain mitochondrial membrane by planar lipid bilayer method. Our results showed the presence of a channel with a conductance of 150 pS at potentials between 0 and –60 mV in 200 cis/50 trans mM KCl solutions.

The channel was voltage-independent, with an open probability value ~0.6 at different voltages. ATP did not affect current amplitude and Po at positive and negative voltages. Notably, adding iberiotoxin, charybdotoxin, lidocaine, and margatoxin had no effect on the channel behavior. Similarly, no changes were observed by decreasing the cis-pH to 6. Interestingly, the channel was inhibited by adding sodium in a dose dependent manner. Our results also indicated a significant increase in mitochondrial complex IV activity and membrane potential and decrease in complex I activity and mitochondrial ROS production in the presence of sodium ions.

We propose that inhibition of mitochondrial K⁺ transport by Na ions on K⁺ channel opening may be important for cell protection and ATP synthesis.

A new report from the National Academies of Sciences, Engineering, and Medicine recommends ways to make supply chains -- the systems that provide populations with critical goods and services, such as food and water, gasoline, and pharmaceuticals and medical supplies – more resilient in the face of hurricanes and other disasters, drawing upon lessons learned from the 2017 hurricanes Harvey, Irma, and Maria.

Tradeshift, a supply...

If we can’t secure the supply chain, eventually everything else will break

The post What happens when the global supply chain breaks? appeared first on WeLiveSecurity

Researchers have discovered high levels of plastic particles and fibres, as well as black carbon (BC), which is formed by the incomplete burning of fossil fuels, in the waters of the Jade Bay, an inshore basin off the coast of Germany in the Southern North Sea. The concentration of suspended particles are of concern because they have the potential to be ingested by fish and other marine life, and enter the food chain.

Green supply chain management (GSCM) is a holistic approach to improving environmental performance along the supply chain. A new study by Italian researchers on over 4000 manufacturing facilities in seven developed countries has indicated that GSCM increases environmental performance.

The application to crops of struvite (magnesium ammonium phosphate) recovered from waste water may cause antibiotic resistance genes (ARGs) present in this fertiliser to enter the food chain. Chinese researchers who conducted this study on Brassica plants suggest that ARGs in struvite pass from the soil into the roots of the plant, and from the roots to the leaves, via the bacterial community already present. The results of this research highlight the need for struvite production methods and agricultural practices that minimise the risk of antibiotic-resistance transmission from struvite to humans or animals via the environment.

An analysis of European retailers revealed a range of initiatives being undertaken to improve the environmental performance of product supply chains. However, it appears that very large grocery retailers are less proactive than specialist and cooperative retailers, owing to their complex supply chains and tendency to consider consumers responsible for environmental improvements.

The pressures facing Indian manufacturers to ‘green’ their supply chain have been explored by a recent study. Both international and national pressures from government and consumers were found to play an important role in whether a company adopts green supply chain management principles, with pressures varying to some degree depending on the business’s sector and size.

A recent study from Finland on the carbon footprint of food can help producers and consumers make choices that lower the food chain’s impact on climate change, by highlighting hotspots in the food chain for improvement and revealing food’s overall impact.

Tracing products through the supply chain is a key feature for all businesses and industries; this is currently possible via automated identification systems that link a product to a database to track its progress, and through information-tracing (‘infotracing’) systems that keep accessible records of this progress. A study now introduces blockchain technology as a way to electronically trace timber as it travels from the forest to final product, using an infotracing system based on open source and Radio Frequency Identification (RFID) technology that retains records in a secure, decentralised, distributed ledger.

Mandatory legislation can play an important role in managers’ decisions to keep their supply chains ‘green’, according to a recent survey of Greek businesses which investigated incentives driving investment in green management practices.

Strict lockdown measures around the world has caused severe delays and logistical issues leading to worldwide PC shipments falling by 8%, technology market analyst firm Canalys said.

Biodiversity’s contribution to ecosystem services in grasslands — at different levels of the food chain (known as trophic levels1) — has been assessed in a new study. Higher species diversity across trophic levels — particularly for plants, insects and soil microbial decomposers — is important for the provision of multiple ecosystem services related to food production, recreational benefits, or climate regulation. Species diversity across different trophic groups was also found to be just as important in controlling ecosystem functioning as the management intensity of grasslands and environmental factors, such as climate or soil type.

Long-chain perfluoroalkyl acids (PFAAs) are persistent chemicals with proven toxic effects. This study estimated the emissions and concentrations of two such chemicals, perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), in 11 of Europe's most populated river catchments. Estimated emissions were lowest in the Thames and highest in the Rhine, while the EU environmental quality standard for PFOS was exceeded in all rivers. This study provides a picture of PFAAs contamination in rivers across Europe, and makes recommendations for achieving reductions.

The “hip, cool and tech-oriented” chain will target millennials.

As commerce becomes increasingly global, American corporations are taking steps to develop sustainable supply chains that span the country and the planet.

The Danish capital's urban 'parkipelago' will eventually include a sauna, cafe and mussel farm.

Eco-friendly supply chain. According to a study by management consulting firm Accenture, companies have found that having an eco-friendly supply chain can save

The disintegration of a giant Antarctic ice shelf that had been stable for millennia was caused by a chain reaction of lakes draining on top of the ice.

Rudi Putra takes on powerful palm oil plantations in the name of conservation — and wins.

Health systems in emerging markets have not realized the benefits of data visibility to global health supply-chain operations. To do so, health-system leaders will need to take four critical actions.

Wired's video series, 'Five Levels of Difficulty,' challenges an expert to explain a complicated concept to people at five levels of expertise — and it's cool.