To navigate the dangerous new era, Keir Starmer must end the culture of denial around the biggest strategic mistake of modern times The 35th anniversary of the Berlin Wall coming down was not commemorated much in Britain last weekend. It is no Poppy Day. The unravelling of the iron curtain doesn’t…

Government to order review of rail fare prosecutions The government is set to order an independent review of rail fare prosecutions and enforcement by train companies following reports of disproportionate action against passengers by revenue protection teams. The BBC understands that Transport…

"We Must Do Whatever It Takes!" - Netherlands Reinstates Temporary Border Controls To Curve Illegal Immigration Authored by Thomas Brooke via Remix News, The Netherlands has announced it will reintroduce internal border checks starting Dec. 9 in fresh efforts to manage illegal immigration. The…

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How are borders made? State borders are the product of political conflict, nationalist discourse, unequal economic systems, and, as this essay shows, significant public financial investment. Public policy and political narratives naturalize state borders, often hiding how their origins are arbitrary and violent. State borders often mark space following war and conflict, but they also […]

The Canadian government on Wednesday ordered ByteDance-owned TikTok to dissolve its operations in the country, citing national security risks, but stopped short of instituting a ban on the popular video-sharing platform. "The decision was based on the information and evidence collected over the course of the review and on the advice of Canada's security and intelligence community and other

This marks the launch of various ventures, including a festival project, a therapeutic space with therapy animals, and a holistic health program for women. 

In this video, Armed Scholar expounds on the recent decision by the US Supreme Court concerning our border and the flooding of illegal immigrants, including the Biden administration, through the Department of Homeland Security, concerning programs set up that promised citizenship to illegal aliens. The decision was handed down following the 2024 elections, striking down …

By Jason Cohen Former MSNBC host Chris Matthews on Wednesday criticized Democrats for their “open border” policy following Vice President Kamala Harris’ loss to former President Donald Trump. Trump clinched the required 270 electoral votes early Wednesday, winning Georgia, North Carolina and Pennsylvania, according to multiple forecasters. Matthews, on “Morning Joe,” argued that Democrats’ lenient […]

The post ‘A Lot Of People Are Very Angry’: Chris Matthews Unloads On Dems Over ‘Open Border’ Policy After Harris Loss appeared first on Liberty Unyielding.

By Harold Hutchison Former Acting Secretary of Homeland Security Chad Wolf told CNN host Jim Acosta Tuesday that the incoming Trump administration would “initiate a pretty large program” to locate children the Biden-Harris administration lost track of. At least 85,000 children placed into the custody of the Office of Refugee Resettlement (ORR) are unaccounted for, […]

The post Former Trump Official Reminds Jim Acosta Of ‘Over 330,000 Children’ Biden-Harris Admin Lost Track Of At Border appeared first on Liberty Unyielding.

Lando Norris takes two points out of Max Verstappen's championship lead with victory in the sprint race at the Sao Paulo Grand Prix.

Homan has described the US border as "the biggest national security vulnerability" the nation has seen since 9/11.

A major incident was declared when the blaze broke out in the London Oratory School in Fulham last year.

Donald Trump has riled the left-wing, anti-American Democrats once again, this time by naming Biden critic and immigration expert Thomas D. Homan as his “border czar.” Homan is an excellent choice for this, certainly. No one knows more about fixing border policy better than Homan who ha spent the last 5 years bedeviling the left […]

The post Donald Trump’s New Border Czar Means Business… and Democrats are Furious appeared first on The Lid.

Olivia Nuzzi has withdrawn her protective order request against her ex-fiancé Ryan Lizza months after her relationship with RFK Jr. was made public.

South Africa has closed the Lebombo port of entry to and from Mozambique after 15 officials from the Ressano Garcia border fled to SA on Thursday morning for protection.

It was business as usual at the Lebombo border post between SA and Mozambique on Saturday morning, with vehicles moving freely between both countries after a shutdown earlier this week.

Mozambican opposition presidential candidate Venancio Mondlane has called for gatherings at ports and borders, and in major cities from Wednesday for what he describes as a fourth round of demonstrations against a stolen election.

The following article, Tom Homan – Trump’s Nominee for the Border, was first published on Conservative Firing Line.

Former Director of ICE Tom Homan is the Trump Nominee for “Border Czar.” But he isn’t the only nominee being named on this Veteran’s Day. Homan is one tough cookie- he will be charged with overseeing the deportations of criminal migrants, as well as the Northern border, aviation security, and maritime security. It’s a tall …

Continue reading Tom Homan – Trump’s Nominee for the Border ...

Team Biden thought it was a clever work-around to open up the border without looking like they were opening the border. Texas took the cheat to court.

The post AMNESTY: Texas & American First Legal Score BIG Win Against Open Border Policy appeared first on Clash Daily.

Investigation by Jeremy Portnoy originally published by RealClearInvestigations and RealClearWire Topline: A $1.4 million state task force created to protect the border between New Hampshire and Canada has not encountered a single illegal border crosser this year, according to data obtained by the American Civil Liberties Union. Key facts: The state has spent $353,425 so …

What is the future of cross-border data flows? 16 September 2024 — 6:00PM TO 7:00PM Anonymous (not verified) 15 August 2024 Chatham House and Online

Navigating long-standing tensions and newfound difficulties for unlocking shared prosperity among modern, digital economies.

Cross-border data flows can unlock shared prosperity among digital economies, advance international security, and address cybercrime and global crises. But ensuring the free flow of data across borders involves navigating complex regulatory, security, trust, political, and technical challenges. Developing effective frameworks and agreements to support data flows is a significant undertaking.

Recent bilateral and multilateral agreements and initiatives have advanced data-sharing, respecting the right to privacy and upholding notions of sovereignty. This has contributed to clearer rules and (potentially) better solutions such as the OECD declaration on government access to data held by companies. Further progress, supportive of public safety and national security, is on the horizon, like G7 support for data free flow with trust and industry-led, trusted cloud principles on protecting human rights and competitiveness.

More work is needed to operationalize commitments and advance ongoing negotiations, like US–EU negotiations on e-evidence in criminal proceedings. This is key for ensuring ‘hard’ legal and regulatory mechanisms complement OECD principles. Stakeholders from law enforcement, national security, data protection and industry must confront tensions between sovereign prerogatives and cooperation. They must also overcome traditional silos between law enforcement and national security work. On the horizon are newfound challenges (for example, in harmonizing legal frameworks and responding to advances in technology). All the while, stakeholders must work together to promote economic interests, data protection, privacy and cybersecurity.

This expert panel discusses the future of cross-border data-sharing, raising questions including:

• What value does cross-border data-sharing bring and where are its current ‘pain points’?
• To enable data free flows, how should principles complement ‘hard’ legal and regulatory mechanisms?
• Beyond states, law enforcement, major industry players and international organizations, what roles should SMEs, the technical community and civil society stakeholders play in shaping and operationalizing principles?
• Looking ahead, where is progress in data-sharing principles and arrangements expected or possible?

A drinks reception follows the event.

This event is supported by Microsoft as part of a project on data sharing. The project has benefited greatly from the insights of a multi-stakeholder taskforce and concludes with an open-access special issue of the Journal of Cyber Policy.

Water, Ecosystems and Energy in South Asia: Making Cross-Border Collaboration Work Research paper sysadmin 29 June 2016

A new paper sets out the factors that have made previous cross-border projects in South Asia successful, arguing that cooperation around water is feasible despite the region’s political differences and economic assymetries.

• The countries of South Asia share some of the world’s major river basins – the Ganga (or Ganges), the Brahmaputra and the Indus. These rivers and their tributaries flow through seven countries, support more than 1 billion people, irrigate millions of hectares of land and are of cultural importance to many of those who rely on them.
• River management presents common challenges across the region. These include physical factors such as droughts, flooding, cyclones and climate change, as well political and institutional factors impeding the development of solutions and policies to improve resource management and reduce vulnerability. Water is increasingly seen as a source of competition, with population growth, industrialization and urbanization exacerbating the pressures on supply.
• Although South Asian examples of regional cooperation in general are limited, there is a clear positive trend. In areas such as disaster response and cross-border power trading, regional and bilateral engagement is beginning to take place. Multilateral official arrangements exist for trade and other economic issues, but there is none on water or ecosystems. However, as the benefits from cooperation become proven, its desirability is likely to gradually enter mainstream policy thinking on water issues.
• This research paper sets out the factors that have enabled cooperation, and the processes adopted, in previous successful cross-border projects. It focuses on four categories of cooperation: development of early-warning systems for natural disasters, in particular floods; protection of cross-border ecosystems; sharing of learning, through the showcasing of innovative approaches in one country that can be adopted by others; and power trading, in particular the development of hydropower in Bhutan and its export to India.
• The paper argues that cooperation around water in South Asia is feasible despite political differences and economic asymmetries. Different forms of collective action, and common understanding of both the threats and the shared benefits from cooperation, are required to foster more partnerships within the river basin states.

Japan’s G7 leadership: Defending the liberal order amid crisis 28 February 2023 — 9:00AM TO 10:00AM Anonymous (not verified) 20 February 2023 Online

How G7 countries should best respond to global economic and security challenges in order to defend the liberal international order.

In May 2023 Japan hosts the G7 summit in Hiroshima, where leaders of the US, UK, Canada, France, Germany and Italy come to discuss the most urgent challenges facing the world.

This year’s summit takes place against a backdrop of continued global economic and political instability from the war in Ukraine to intensifying competition between China and the West.

The speakers discuss Japanese Prime Minister Fumio Kishida’s priorities at the summit and consider how G7 countries should best respond to global economic and security challenges in order to defend the liberal international order.

This event is the third of a three-part series held in partnership with Japan House London.

Watch the first event which looked at Africa-Japan relations here, and the second event, on the UK and Japan’s engagement with Southeast Asia, here.

New essay anthology examines the future of the international order News release jon.wallace 7 May 2021

Featuring a new essay by Robin Niblett, Chief Executive of Chatham House, and Leslie Vinjamuri, Director of the US and Americas programme.

“Anchoring the World”, a new anthology, features an important new essay by Robin Niblett, Chief Executive of Chatham House, and Leslie Vinjamuri, Director of the US and Americas programme. The essay, “The Liberal Order Begins At Home”, argues powerfully for the revival of a liberal international order.

The essay collection has been produced by the Lloyd George Study Group on World Order, and celebrates the centennial years of Chatham House, Georgetown University’s School of Foreign Service, and the Council on Foreign Relations.

Robin Niblett said:

“In this excellent collection, some authors argue that the United Nations should continue to anchor the international system, while others argue for the creation of a new Concert of Powers.

“Our essay argues that it is both necessary and possible to revive the idea of a liberal international order: necessary (and urgent) because of heightened global competition with China, and possible only if western democracies repair their deep social and economic problems at home.

“We hope this volume carries forward the fortitude and creative spirit that the School of Foreign Service, Chatham House, and the Council on Foreign Relations have brought to the study and practice of international affairs over the past century.”

The Lloyd George Study Group and book were made possible by the generosity of the family of Robert Lloyd George, the great-grandson of British Prime Minister, David Lloyd George.

Anchoring the World is published by Foreign Affairs magazine.

Cross-border conflict, evidence, policy and trends (XCEPT)

This five-year policy-focused research programme seeks to respond to the challenges of long-term cross-border conflicts by exploring the drivers behind them.

dora.popova 26 August 2021

Protracted conflicts in the Middle East and North Africa, Horn of Africa and parts of Asia, although usually arising from intra-state disputes, rarely remain contained within national borders. Their effects reverberate outward and external actors are drawn in.

The longer these wars last, the more difficult they are to resolve as the interests of international actors collide and the web of economic and political interactions which sustain violence and connect conflict across borders expand and deepen.

The Cross-border conflict, evidence, policy and trends (XCEPT) research programme brings together world-leading experts to examine conflict-affected borderlands, how conflicts connect across borders, and the drivers of violent and peaceful behaviour.

Chatham House provides research leadership to the programme, as part of the wider consortium, and our research explores:

• the intersection of conflict supply chains which sustain and embed violence
• coping supply chains for survival-based economic activity which occurs in the context of violence

Three geographic case studies will be supported by cross-cutting workstreams on gender and social inclusion, livelihoods, and border security. Each will produce analysis and recommendations to inform international policy responses to conflict across borders.

These case studies will focus on:

• armed actors and financial flows through Iraq and the Levant
• human smuggling across Libya, East and West Africa
• gold mining and weapons flows across Sudanese borderlands

The consortium is made up of a range of other organizations, including the Asia Foundation, the Malcolm H. Kerr Carnegie Middle East Center, the Rift Valley Institute, Chemonics UK and King’s College London.

XCEPT is funded by UK Aid from the UK government.

Evolving Turkey–Iran relations and implications for regional reordering

This project examines the nature of the bilateral relationship between Turkey and Iran in relation to Middle Eastern countries and in the context of broader regional dynamics.

LJefferson 16 October 2024

The 2016–21 period in Turkish–Iranian relations, which was marked by both sides’ structured cooperation through the Astana Process and Sochi summits on conflict management in Syria, and their largely shared opposition to US policy in Syria and at the broader regional level, to Iraqi Kurdistan’s independence referendum, and to the blockade of Qatar, has run its course. 

However, the new shape of these bilateral relations remains undefined, and understanding them is essential to effective policymaking in the region. How they will evolve will have direct ramifications for Iraq, Syria, regional Kurdish geopolitics, and the process of regional reordering and connectivity in the Middle East and South Caucasus. They will also have direct implications for US and European policymaking and role in the region. 

This project studies the evolving nature of Turkish–Iranian relations through Iraq, Syria and regional Kurdish politics. It examines how Turkey and Iran approach regional connectivity projects and major regional initiatives, and how ongoing regional developments, including the war in Gaza, have and may impact Turkey–Iran relations and EU, US and UK security considerations and policy towards the two countries.

The Centre for Applied Turkey Studies (CATS) at the Stiftung Wissenschaft und Politik (SWP) in Berlin is funded by Stiftung Mercator and the Federal Foreign Office. CATS is the curator of the CATS Network, an international network of think-tanks and research institutions working on Turkey. 

Evolving Turkey–Iran Relations and Implications for Regional Reordering is a project of the CATS Network.

Linda J. Pike
Apr 1, 2003; 44:655-667
Thematic Reviews

Expert

Dr Yu Jie

Constantin Carle and Marlis Hochbruck
Math. Comp. 93 (), 2611-2641.
Abstract, references and article information

Buyang Li, Zongze Yang and Zhi Zhou
Math. Comp. 93 (), 2557-2586.
Abstract, references and article information

Dylan Langharst and Dongmeng Xi
Proc. Amer. Math. Soc. 152 (), 5299-5311.
Abstract, references and article information

Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from an initial low affinity to a higher affinity. However, little is known about the molecular changes in the binding mechanism that would facilitate such a transition. We previously showed that the interaction between two intrinsically disordered domains, NCBD and CID, likely emerged in an ancestral deuterostome organism as a low-affinity interaction that subsequently evolved into a higher-affinity interaction before the radiation of modern vertebrate groups. Here we map native contacts in the transition states of the low-affinity ancestral and high-affinity human NCBD/CID interactions. We show that the coupled binding and folding mechanism is overall similar but with a higher degree of native hydrophobic contact formation in the transition state of the ancestral complex and more heterogeneous transient interactions, including electrostatic pairings, and an increased disorder for the human complex. Adaptation to new binding partners may be facilitated by this ability to exploit multiple alternative transient interactions while retaining the overall binding and folding pathway.