In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases--two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord. After years of investigating the diseases' underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.

In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases--two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord. After years of investigating the diseases' underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.

DUSHANBE, 8 June 2016 – A one-year learning course on Border Security and Management for Senior Leadership (BSMSL) was launched with an introductory meeting that took place in Dushanbe from 6-8 June.

The course was designed and developed by the OSCE Border Management Staff College and the Geneva Centre for the Democratic Control of Armed Forces (DCAF), and aims to enhance the knowledge, competencies and leadership potential of mid- to senior-level professionals working in the area of border security and management.

Twenty-four participants from Afghanistan, Bosnia and Herzegovina, Georgia, Jordan, Lithuania, Moldova, Poland, Portugal, Tajikistan, Tunisia and Ukraine will participate in the course, providing a comprehensive insight into the contemporary security environment, leadership and management competencies as well as mechanisms to prevent and combat existing and emerging security threats and challenges.

The course programme is divided in three modules that involve participants in fact-finding, analyzing, decision-making, and management activities. Its format provides an opportunity to draw from various international best practices and expertise, putting emphasis on co-operation between operational and academic approaches and encouraging peer-learning.

Each module is presented through a variety of training and learning methods, including e-learning, face-to-face study, follow-on discussions and follow-up activities, group exercises, and study visits.

“Borders exist to unite people and not to divide them. This course is one of the college’s long-term initiatives aiming to promote and implement the concept of open but secure borders. With the knowledge obtained here participants will not only be able to enhance their professional skills but also be capable to develop and provide analysis and recommendations to improve capacities and the situation at borders,” said Ambassador Marcel Pesko, Director of the OSCE Conflict Prevention Centre, while addressing the BSMSL participants.

Andrus Oovel, Head of the DCAF Border Security Programme added: “This course is a combination of social, political and security science, covering a wide range of academic disciplines on global governance and security, humanities, law, criminal justice and studies which include leadership and management for strategic and operational planning in managing migration, border security, and trade facilitation.”

ALMATY, Kazakhstan, 22 June 2016 – An OSCE-supported train-the-trainer regional course on document security for some 20 border guards from Kazakhstan, Kyrgyzstan, Tajikistan and Uzbekistan began today in Almaty, Kazakhstan.

The three-day event is organized by the OSCE Programme Office in Astana in co-operation with the EU-funded Border Management Programme in Central Asia (BOMCA).

Experts from Latvia and Slovakia will share best practices in international document security, including the identification of falsified travel documents, document control, the use of paper and polymer substrates in document security, conventional printing techniques, photo protection, secondary verification, and profiling techniques to identify potential criminals during the border crossing check-up procedure. The participants will also have an opportunity to work with genuine and falsified travel documents from different countries in order to utilize the new methods learned in the course.

“In order to protect a country’s borders, it is crucial to know what verification methods are used in all travel documents and the common features of forged documents,” said Colin McCullough, Political Officer at the OSCE Programme Office in Astana. “This is best done through consistent familiarization on relevant technology and regular exchange of information and experience with other relevant authorities,”

Gunta Laganovska, a trainer at the seminar and Chief of the Expert Service, Central Department of the State Border Service for the Republic of Latvia, said: “International co-operation between border services is a crucial part of a system to prevent illegal migration. The exchange of information and experience in identifying forged documents enables the growth of the professionalism of all participants in this seminar. The train-the-trainers approach allows for the possibility to transfer new skills to a large number of border guards where they work.”

The seminar is part of the Office’s long-standing efforts to promote the OSCE border security concept and counter transnational crime in the host country.

BISHKEK, 8 July 2016 – As part of the first phase of the two-day military Command-Staff Exercise ‘Barrier 2016’, representatives of the State Border Service (SBS), local authorities and civil society of Osh region focused on border security and management problems during a roundtable discussion and video-conference supported by the OSCE Centre in Bishkek.

The discussions, held at the SBS headquarters, aimed to promote co-operation between the military, law enforcement agencies and civil society and improve the existing mechanisms of co-ordination. Participants were able to directly ask border management-related questions to the deputies of Jogorku Kenesh (the parliament), government officials and SBS representatives.

Head of the SBS Colonel Abdikarim Alimbaev detailed the complex measures taken by the Service to strengthen the Kyrgyz-Uzbek and Kyrgyz-Tajik border areas, such as improving the infrastructure of border units and setting additional border barriers and posts. “Through improved relations with neighbouring countries, the strengthening of border security and management will ensure the sovereignty and territorial integrity of the State and in this way safeguard peace and stability in the specific border areas and in the broader Central Asian region,” he said.

Daniele Rumolo, acting Head of the OSCE Centre in Bishkek highlighted the crucial significance of border security for Kyrgyzstan: “Effective counter-efforts to the current challenges remain the most relevant strategic priority for continuous co-operation and also an important aspect of OSCE activities in the framework of transnational threats. The OSCE Centre in Bishkek greatly values its engagement and interaction with the Kyrgyz Government and the SBS, and expresses its readiness to further develop the co-operation in this field.”

Vice Prime-Minister on border issues Jenish Razakov stressed the importance of co-operation between security and law enforcement agencies and local governments, stating that in their absence it would be impossible to resolve border crises. He also noted that in the past two years such joint exercises to enhance the combat readiness of units have demonstrated positive results.

On 8 July, following the roundtable discussion and video-conference in Bishkek, the practical phase of the ‘Barrier 2016’ simulation exercise took place in Osh with the participation of the Special Forces Unit, the SBS, Ministry of Emergency Situations, and the Armed Forces of the Kyrgyz Republic.

The Command-Staff Exercise ‘Barrier 2016’ was held jointly by the SBS and the OSCE Centre in Bishkek as part of the Centre’s project to enhance the ability of the Kyrgyz Government to engage in regional co-operation on border security and management. 

DUSHANBE, 5 August 2016 – Twenty officers  of the Tajik Border Troops, ranked between warrant officer and major, mainly coming from border detachments  on the Afghan and Tajik border, successfully completed a four-week course today on patrolling and leadership at the Gissar Training Centre in Dushanbe.

The course, organized by the OSCE Office in Tajikistan, focused on enhancing participants’ knowledge of conducting observation missions using topographical maps, satellite imagery and other tools. They also learned about reporting and analysis, repelling methods, communications and tactical movement.

Uniforms and common tactical equipment were given to each participant. Separate medical lessons were delivered by trainers from the United States Embassy in Tajikistan. The sessions on gender mainstreaming and demining awareness were delivered by experts of the OSCE Office. Two officers of the Tajik Border Troops, who previously passed the course, also supported the OSCE in delivering the lessons.

OSCE Office in Tajikistan Counter-terrorism and Police issues Adviser Wolfgang Nikolaus, congratulated the officers on completing the course and said: “The OSCE continues supporting efforts to enhance the capacity of Tajik Border Troops Staff by providing such high-quality training courses."

The course is the eighth to be held under the third phase of the Patrol Programming and Leadership Project. The Project aims to increase the capacities of Tajik border staff in detection and interdiction of illegal cross-border movements.

DUSHANBE, 5 August 2016 – Twenty officers  of the Tajik Border Troops, ranked between warrant officer and major, mainly coming from border detachments  on the Afghan and Tajik border, successfully completed a four-week course today on patrolling and leadership at the Gissar Training Centre in Dushanbe.

The course, organized by the OSCE Office in Tajikistan, focused on enhancing participants’ knowledge of conducting observation missions using topographical maps, satellite imagery and other tools. They also learned about reporting and analysis, repelling methods, communications and tactical movement.

Uniforms and common tactical equipment were given to each participant. Separate medical lessons were delivered by trainers from the United States Embassy in Tajikistan. The sessions on gender mainstreaming and demining awareness were delivered by experts of the OSCE Office. Two officers of the Tajik Border Troops, who previously passed the course, also supported the OSCE in delivering the lessons.

OSCE Office in Tajikistan Counter-terrorism and Police issues Adviser Wolfgang Nikolaus, congratulated the officers on completing the course and said: “The OSCE continues supporting efforts to enhance the capacity of Tajik Border Troops Staff by providing such high-quality training courses."

The course is the eighth to be held under the third phase of the Patrol Programming and Leadership Project. The Project aims to increase the capacities of Tajik border staff in detection and interdiction of illegal cross-border movements.

Related Stories

• OSCE Office in Tajikistan organizes workshop on verifying the authenticity of security documents
• OSCE Office in Tajikistan donates audio-visual material to enhance interactive teaching at Police Academy
• OSCE Office in Tajikistan support Garm’s local authorities in strengthening referral mechanisms for protecting domestic violence victims

ULAANBAATAR, 30 June 2016 – Election day was orderly and followed a competitive campaign. This, however, did not offset the impact of late fundamental changes to election laws on Mongolia’s democratic development, the international observers concluded in a preliminary statement released today. While the June 29 parliamentary elections were highly contested and freedoms of assembly and association were respected, restrictive campaign provisions, coupled with the media’s subservience to political interests, limited impartial and comprehensive information available to voters, the statement says.

“We were pleased to see that voting took place in a calm and peaceful manner. This was a genuinely competitive contest, with high turnout and no certainty as to which party would win. We applaud the fact Mongolia is a functioning democracy,” said Laima Liucija Andrikienė, Head of the European Parliament delegation. “There were, however, some elements which cause concern, including significant last-minute changes to the election laws, which, among other things, prevented 150,000 Mongolian citizens living outside the country, including diplomats, from voting.”

The observers said the consolidation of election legislation into a new law adopted on 25 December 2015, following an inclusive process, was a positive development toward establishing a cohesive electoral framework. However, changes in May 2016 – from a mixed electoral system to a solely majoritarian one, establishing 76 single-mandate constituencies and approving their boundaries – were introduced by parliament in a process that lacked transparency, public consultation and adherence to established criteria, the observers said. This resulted in profound population discrepancies among constituencies.

A total of 498 candidates, including 69 independents, was registered in a process that was largely inclusive and provided voters with a range of political choices. Contrary to OSCE commitments and other international obligations, however, there are disproportionate restrictions on candidacy rights the statement says. While there was general confidence in the accuracy and inclusiveness of the voting register, the May changes to the election laws also effectively disenfranchised 150,000 citizens living abroad for the parliamentary elections.

“For an election to be meaningful, voters first have to be offered a genuine choice, and voters were given that choice here. That choice also has to be between candidates competing on a level playing field and who have equal access to independent media to explain their platforms. In this, there is still work to do,” said Ambassador Audrey Glover, Head of the OSCE/ODIHR long-term election observation mission. “Elections are about voters, and the main problem for voters was understanding the significant last-minute changes to election laws, which affected the rules of the game profoundly and raised questions about political motivation.” 

Despite undue campaign restrictions, the freedoms of assembly and association were respected and candidates were generally able to convey their messages to the electorate. At times the lines were blurred between parties and the administration at both the national and local levels, the observers said. There were multiple instances of alleged vote-buying, which resulted in a number of formal complaints and the deregistration of two candidates.

The GEC received some 50 pre-election complaints. Courts reviewed 21 cases regarding candidate registration, and the police handled more than 1,000 campaign-related complaints. Although legislation clarifies the complaints and appeals process to some extent, a general lack of formalization and transparency in the process within the election administration and the protracted handling of disputes in courts undermined the right to effective remedy.

The media offered extensive election coverage, but abandoned their journalistic role, for the most part simply granting direct access to the politicians. Paid political advertisements and free airtime overshadowed editorial content, and campaign material prepared by political parties was also included in news programming, undercutting the credibility of the media. Consequently, voters were deprived of independent and analytical reporting, the observers said.

In preparation for election day, the General Election Commission met key operational deadlines and fulfilled its mandate. At the same time, the observers said, it lacked transparency and accountability to stakeholders, diminishing trust in the credibility of the process. The testing of vote-counting machines was conducted professionally by the Commission in the presence of stakeholders and, to address concerns over the machines’ accuracy and integrity, the law was amended stipulate that up to 50 per cent of polling stations would be subject to manual recounts. The procedures stipulating the manual re-count, however, were only finalized two days prior to the elections.

All parties and coalitions complied with the 20 per cent gender quota provided for by law, and 26 per cent of contestants were women. There were, however, no women candidates in more than one-third of the constituencies. While there is only one woman member of the General Election Commission, women were better represented in lower-level election commissions. Overall, women remain underrepresented in political life.

Election day proceeded in an orderly manner in most of the country and, while the right to vote was respected, the secrecy of the vote was not consistently ensured. The observers’ assessment of the counting and tabulation of votes was a notable exception to the overall positive assessment of voting, mostly as a result of significant procedural errors or omissions. A number of civil society organizations monitored the pre-election environment, including campaign finance and the media, and issued timely statements highlighting key shortcomings.

For further information, contact:
Thomas Rymer, OSCE/ODIHR, +976 95 14 1635 or +48 609 522 266, thomas.rymer@odihr.pl

Tim Boden, European Parliament, +976 99 976294 or +32 473 844431, timothy.boden@europarl.europa.eu

Related Stories

• OSCE/ODIHR opens election observation mission for parliamentary elections in Mongolia
• International election observers in Mongolia to hold press conference on Thursday
• OSCE/ODIHR observers to hold press conference in Ulaanbaatar on Friday

DUSHANBE, 5 August 2016 – Twenty officers  of the Tajik Border Troops, ranked between warrant officer and major, mainly coming from border detachments  on the Afghan and Tajik border, successfully completed a four-week course today on patrolling and leadership at the Gissar Training Centre in Dushanbe.

The course, organized by the OSCE Office in Tajikistan, focused on enhancing participants’ knowledge of conducting observation missions using topographical maps, satellite imagery and other tools. They also learned about reporting and analysis, repelling methods, communications and tactical movement.

Uniforms and common tactical equipment were given to each participant. Separate medical lessons were delivered by trainers from the United States Embassy in Tajikistan. The sessions on gender mainstreaming and demining awareness were delivered by experts of the OSCE Office. Two officers of the Tajik Border Troops, who previously passed the course, also supported the OSCE in delivering the lessons.

OSCE Office in Tajikistan Counter-terrorism and Police issues Adviser Wolfgang Nikolaus, congratulated the officers on completing the course and said: “The OSCE continues supporting efforts to enhance the capacity of Tajik Border Troops Staff by providing such high-quality training courses."

The course is the eighth to be held under the third phase of the Patrol Programming and Leadership Project. The Project aims to increase the capacities of Tajik border staff in detection and interdiction of illegal cross-border movements.

Related Stories

• OSCE Office in Tajikistan organizes workshop on verifying the authenticity of security documents
• OSCE Office in Tajikistan donates audio-visual material to enhance interactive teaching at Police Academy
• OSCE Office in Tajikistan support Garm’s local authorities in strengthening referral mechanisms for protecting domestic violence victims

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If you need any lifting gloves/straps for the gym, I normally purchase a pair of these leather ones every year around this time for around $26 - https://www.thewodlife.com.au/products/twl-leather-gymnastic…

However for an even cheaper price and bigger saving, the (supposedly better/higher quality) karbon version is currently on sale for $20 (which is a $65 saving) - https://www.thewodlife.com.au/products/twl-2-finger-karbon-g…. I actually bought these last week for $26, and now they are even cheaper in price :(

I don't like to wear full gloves, but still like to wear something to prevent too many calluses and also so my hands are not completely black from the dirty gym equipment. They come in a pouch as well so they get aired out and don't come into direct contact with the other items in your gym bag.

Lots of other deals on like Nano's, Metcon, etc for their Black Friday Sale.

The Swedish automaker has added an entry-level version of the Polestar 3.

On Tuesday’s broadcast of the Fox News Channel’s “Your World,” former Border Patrol Chief Raul Ortiz stated that, during the Biden administration, “One of the things we struggled with when I was the Chief was getting engagement from policy officials

The post Fmr. Biden Border Patrol Chief: Homan Will Fix Many Issues I Had with Biden, Picking Him ‘a Tremendous Step’ appeared first on Breitbart.

SEPM union that represents magazine staff in France alleges that the search giant was going to start testing a scheme under which it would remove from search results some articles from media with which it was clashing over rights for use of online news.

The criminal drug cartels in Mexico are reportedly rushing thousands of illegals across the southern U.WS. border in an effort to get as many criminal operatives inside the country as possible ahead of Donald Trump’s inauguration. With more than 11 million illegals already having crossed into the U.S. thanks to Joe Biden’s disastrous border policies, […]

The post Report: Drug Gangsters Sending Thousands of Illegal Across Border to Beat Trump Inauguration appeared first on The Lid.

Indiana Jones and the Great Circle aims to put you in control of the wild and wacky adventures you’ve seen… Continue reading Indiana Jones and the Great Circle pre-order bonus explained

The post Indiana Jones and the Great Circle pre-order bonus explained appeared first on ReadWrite.

The Border Management Authority has confirmed that it has temporarily suspended operations at the Lebombo port of entry due to ongoing post-election unrest in Mozambique on Wednesday.

Israel suffered one of the deadliest days of its ground offensive against Hezbollah in Lebanon when six of its soldiers were killed in combat near the border.

A new report said that a draft order creating a mechanism for reviewing America’s top military leaders is being considered by President-elect Donald Trump’s transition team. The Wall Street Journal […]

The post Trump Team Prepping 'Warrior Board' Executive Order in Bid to Purge Military of Wokeness: Report appeared first on The Western Journal.

Marco Jansen's late pyrotechnics were not enough to save South Africa as they slid to a 11-run defeat against India in the third T20 at SuperSport Park on Wednesday.

TOKYO, Nov. 13, 2024 — NEC Corporation has received an order for a next-generation supercomputer system from Japan’s National Institutes for Quantum Science and Technology (QST), under the National Research […]

The post NEC Secures Order for Advanced Supercomputer to Drive Fusion Science Research at Japan’s National Institutes appeared first on HPCwire.

Two explosions near Brazil's Supreme Court and Congress forced evacuations Wednesday night with one man found dead in what some authorities are calling a suicide attack.

A judge has temporarily ordered Oakland International Airport in California to stop using the name "San Francisco Bay Oakland International Airport" as the cities' legal battle plays out.

The United States is expanding the number of lanes at the Pacific Highway border crossing from Surrey, B.C., to Blaine, Wash. The $33 million US ($46 million) contract will increase the number of entry lanes from six to 10.

ABC News’ Linsey Davis spoke with Rep. Monica De La Cruz of Texas about securing a second term.

A source says over 1 300 customers have been lured away using data allegedly harvested by a franchise employee.

A Meta lawyer told the FTC’s five commissioners at a hearing Tuesday that the consumer protection agency doesn’t have authority to modify the agreement without the company’s consent.

PORT-AU-PRINCE — Doctors Without Borders (MSF) said on Wednesday that at least two patients were killed when its ambulance was stopped and attacked earlier this week in Haiti's capital Port-au-Prince.  The MSF staff said they were violently attacked on Monday after "members of a vigilante group and law enforcement officers" stopped the ambulance.  The ambulance, transporting three young people with gunshot wounds, was halted about 100 meters from the MSF hospital in the Drouillard area of the capital and forced to transfer the patients to a public hospital, MSF said.  The group said police attempted to arrest the patients before escorting the ambulance to the hospital, where "law enforcement officers and members of a self-defense group surrounded the ambulance, slashed the tires, and tear-gassed MSF staff inside the vehicle to force them out."  The wounded patients were taken a short distance away and at least two were executed, the group said.  "The act is a shocking display of violence and it seriously calls into question MSF's ability to continue delivering essential care to the Haitian people," said Christophe Garnier, MSF's head of mission.

If an executive order is enacted, it could fast-track removal of admirals

President-elect Trump has chosen South Dakota Gov. Kristi Noem to lead the Department of Homeland Security. This is what to know about her background.

More than a thousand kids taken from their parents at the border still have not been reunited. The man Trump has named his next border czar has been described as the family separation architect.

1. 'Australia, we have arrived!': Team India announces as Border-Gavaskar Trophy prep in full swing  The Times of India
2. Watch: Virat, Bumrah and others grind hard in Perth ahead of 1st Test vs Australia  India Today
3. 'Australia, We Have Arrived': After Claims Of Secrecy, India Release Video Of Training Session And Send Mes  News18
4. Black veil of secrecy: India begin training in privacy in Perth  ESPNcricinfo
5. 'Practice Session Open To All': BCCI Refutes Aussie Media's Reports Of Closed Door Sessions  Times Now

U.S. president-elect Donald Trump's border czar says there is an "extreme national security vulnerability" along the Canada-U.S. border that he plans to deal with the moment the new Republican administration takes power.

Donald Trump's second administration is filling up with some of his most loyal supporters and many of the people landing top jobs have been critical of Prime Minister Justin Trudeau and security at Canada's border.

The Delhi High Court has ordered the Bureau of Immigration to cancel a Look Out Circular (LOC) issued against BharatPe's former Managing Director Ashneer Grover and his wife Madhuri Jain Grover.

All India Majlis-e-Ittehadul Muslimeen (AIMIM) President Asaduddin Owaisi on Wednesday welcomed the Supreme Court order on 'bulldozer justice'.

Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre

On the govt.’s allegation of his being involved in “anti-India activities”, the court says the notice lacks specific details or evidence supporting these claims

Saatvik Green Energy partners with Maharashtra State Electricity Distribution Company to supply solar submersible pumps, supporting sustainable irrigation solutions.

The knives have come out. CNN is hosting many of these right wing Democrats who make millions off the party and its members and then use right wing rhetoric to take it down after their own failures.

I put up the entire transcript of his sleepwalking nonsense of what the Democratic party is. Reiness' version of what what he perceives the party is comes right out of the the dead hands of Roger Ailes.

It's ludicrous. Every "woke" complaint he has comes right out of the mouth of Christopher Rufo. Anus Reiness has taken Kellyanne Conway's alternative facts nonsense to the extreme. How CNN believes this man speaks for the party is beyond me.

REINESS: Either way, here's the problem, I'm not concerned right now what the right thinks about the Democratic Party.

I'm concerned about what I think about the Democratic Party. I don't like to echo the congressmen, all three of them, I don't like the fact that a small portion of our party is pretty much dictating where we are. That they are pretty much, we are being branded as the most extreme of us. It is not only politically problematic, as we just saw, because none of this stuff helped the other day.

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Tim and Sophie, an Australian couple with OM in Paris, experienced life in North Africa, and its many different needs and difficulties, through Transform 2012.

A group of 32 Salvadorians recently crossed borders to share the gospel with people in Belize.

Australia batter Usman Khawaja has laughed off the subject of Nathan McSweeney's strike rate of 41.92 being lower than his in Tests 48.3.